ATE263559T1 - Zubereitungen enhaltend eine nitroneverbindung für die verwendung bei der behandlung von uveitis - Google Patents
Zubereitungen enhaltend eine nitroneverbindung für die verwendung bei der behandlung von uveitisInfo
- Publication number
- ATE263559T1 ATE263559T1 AT97921289T AT97921289T ATE263559T1 AT E263559 T1 ATE263559 T1 AT E263559T1 AT 97921289 T AT97921289 T AT 97921289T AT 97921289 T AT97921289 T AT 97921289T AT E263559 T1 ATE263559 T1 AT E263559T1
- Authority
- AT
- Austria
- Prior art keywords
- uveitis
- compound
- nitronic
- treatment
- preparations containing
- Prior art date
Links
- 206010046851 Uveitis Diseases 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 206010061218 Inflammation Diseases 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 230000004054 inflammatory process Effects 0.000 abstract 1
- -1 nitrone compound Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C291/00—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00
- C07C291/02—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/24—Oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Ophthalmology & Optometry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1627696P | 1996-04-23 | 1996-04-23 | |
| PCT/US1997/006604 WO1997039751A1 (en) | 1996-04-23 | 1997-04-23 | Compositions comprising a nitrone compound for use in treating ocular inflammation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE263559T1 true ATE263559T1 (de) | 2004-04-15 |
Family
ID=21776304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97921289T ATE263559T1 (de) | 1996-04-23 | 1997-04-23 | Zubereitungen enhaltend eine nitroneverbindung für die verwendung bei der behandlung von uveitis |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US5972977A (de) |
| EP (1) | EP0910370B1 (de) |
| JP (1) | JP2000509375A (de) |
| CN (1) | CN1219130A (de) |
| AT (1) | ATE263559T1 (de) |
| AU (1) | AU721531B2 (de) |
| CA (1) | CA2252494A1 (de) |
| DE (1) | DE69728536T2 (de) |
| IL (1) | IL126725A0 (de) |
| NO (1) | NO984920L (de) |
| NZ (1) | NZ332561A (de) |
| TW (1) | TW450952B (de) |
| WO (1) | WO1997039751A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050107366A1 (en) * | 1991-06-18 | 2005-05-19 | Carney John M. | Spin trapping pharmaceutical compositions and methods for use thereof |
| CN1299278A (zh) * | 1998-03-13 | 2001-06-13 | 桑道药品有限公司 | 血管生成抑制 |
| US6083989A (en) * | 1999-05-18 | 2000-07-04 | Centaur Pharmaceuticals, Inc. | Aryl nitrone therapeutics for the treatment of inflammatory bowel disease |
| SI1077694T1 (en) * | 1998-05-19 | 2004-10-31 | Renovis, Inc. | Aryl nitrone therapeutics for the treatment of inflammatory bowel disease |
| US6194465B1 (en) | 1998-05-19 | 2001-02-27 | Centaur Pharmaceuticals, Inc. | Benzamide therapeutics for the treatment of inflammatory bowel disease |
| ATE267804T1 (de) * | 1998-07-17 | 2004-06-15 | Renovis Inc | Alpha-(2-hydroxyphenyl)nitrone, diese enthaltenden pharmazeutische zubereitungen sowie deren verwendung zur behandlung von entzündungen |
| UA66401C2 (en) * | 1998-12-02 | 2004-05-17 | Sentor Pharmaceuticals Inc | 3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical composition containing the same |
| US6730700B2 (en) * | 1998-12-02 | 2004-05-04 | Renovis, Inc. | 3,4,5,-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing the same |
| WO2000074672A1 (en) * | 1999-06-09 | 2000-12-14 | Department Of The Army, U.S. Government | Method and compositions for treating and preventing retinal damage |
| US20050059638A1 (en) * | 2003-08-04 | 2005-03-17 | Kelly Michael G. | Aryl, heteroaromatic and bicyclic aryl nitrone compounds, prodrugs and pharmaceutical compositions of the same to treat human disorders |
| US20050182060A1 (en) * | 2004-02-13 | 2005-08-18 | Kelly Michael G. | 2-Substituted and 4-substituted aryl nitrone compounds |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4153722A (en) * | 1977-10-06 | 1979-05-08 | William H. Rorer, Inc. | Method of treatment |
| DE69012138T2 (de) * | 1989-10-17 | 1995-04-06 | Oklahoma Med Res Found | Verfahren und zubereitungen zur hemmung von mit oxidativer schädigung assoziierten krankheiten. |
| US5036097A (en) * | 1989-10-17 | 1991-07-30 | Oklahoma Medical Research Foundation | Phenylbutyl nitrone compositions and methods for prevention of gastric ulceration |
| US5025032A (en) * | 1989-10-17 | 1991-06-18 | Oklahoma Medical Research Foundation | Phenyl butyl nitrone compositions and methods for treatment of oxidative tissue damage |
| ATE209908T1 (de) * | 1991-06-18 | 2001-12-15 | Oklahoma Med Res Found | RADIKALFÄNGER (ßSPIN TRAPSß) ZUR BEHANDLUNG VON MIT OXIDATION VON LIPIDEN UND PROTEINEN VERBUNDENEN ERKRANKUNGEN |
| US5455272A (en) * | 1993-10-22 | 1995-10-03 | Oklahoma Medical Research Foundation | Spin trap nitronyl hindered phenols |
-
1997
- 1997-04-23 IL IL12672597A patent/IL126725A0/xx unknown
- 1997-04-23 JP JP9538232A patent/JP2000509375A/ja not_active Ceased
- 1997-04-23 TW TW086105289A patent/TW450952B/zh not_active IP Right Cessation
- 1997-04-23 DE DE69728536T patent/DE69728536T2/de not_active Expired - Fee Related
- 1997-04-23 US US08/847,386 patent/US5972977A/en not_active Expired - Fee Related
- 1997-04-23 NZ NZ332561A patent/NZ332561A/en unknown
- 1997-04-23 WO PCT/US1997/006604 patent/WO1997039751A1/en active IP Right Grant
- 1997-04-23 CN CN97194855A patent/CN1219130A/zh active Pending
- 1997-04-23 EP EP97921289A patent/EP0910370B1/de not_active Expired - Lifetime
- 1997-04-23 AU AU27366/97A patent/AU721531B2/en not_active Ceased
- 1997-04-23 CA CA002252494A patent/CA2252494A1/en not_active Abandoned
- 1997-04-23 AT AT97921289T patent/ATE263559T1/de not_active IP Right Cessation
-
1998
- 1998-10-22 NO NO984920A patent/NO984920L/no not_active Application Discontinuation
-
1999
- 1999-09-20 US US09/399,733 patent/US6140356A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69728536D1 (de) | 2004-05-13 |
| WO1997039751A1 (en) | 1997-10-30 |
| NZ332561A (en) | 2001-01-26 |
| EP0910370B1 (de) | 2004-04-07 |
| DE69728536T2 (de) | 2005-02-24 |
| TW450952B (en) | 2001-08-21 |
| JP2000509375A (ja) | 2000-07-25 |
| AU721531B2 (en) | 2000-07-06 |
| EP0910370A1 (de) | 1999-04-28 |
| NO984920L (no) | 1998-12-23 |
| IL126725A0 (en) | 1999-08-17 |
| AU2736697A (en) | 1997-11-12 |
| US5972977A (en) | 1999-10-26 |
| US6140356A (en) | 2000-10-31 |
| CA2252494A1 (en) | 1997-10-30 |
| NO984920D0 (no) | 1998-10-22 |
| CN1219130A (zh) | 1999-06-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |