ATE262033T1 - Methode für die selektive protektion der proliferation der normalen zellen und der selektiven beseitigung der tumorzellen, die eine inaktivierte p53 pathway haben - Google Patents

Methode für die selektive protektion der proliferation der normalen zellen und der selektiven beseitigung der tumorzellen, die eine inaktivierte p53 pathway haben

Info

Publication number
ATE262033T1
ATE262033T1 AT00964630T AT00964630T ATE262033T1 AT E262033 T1 ATE262033 T1 AT E262033T1 AT 00964630 T AT00964630 T AT 00964630T AT 00964630 T AT00964630 T AT 00964630T AT E262033 T1 ATE262033 T1 AT E262033T1
Authority
AT
Austria
Prior art keywords
selective
pathway
cells
tumor cells
inactivated
Prior art date
Application number
AT00964630T
Other languages
English (en)
Inventor
Franco Tato'
Antonio Zanetti
Milena Grossi
Original Assignee
Uni Degli Studi Di Roma Sla Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uni Degli Studi Di Roma Sla Sa filed Critical Uni Degli Studi Di Roma Sla Sa
Application granted granted Critical
Publication of ATE262033T1 publication Critical patent/ATE262033T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081Purging biological preparations of unwanted cells
    • C12N5/0093Purging against cancer cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
AT00964630T 1999-09-21 2000-09-21 Methode für die selektive protektion der proliferation der normalen zellen und der selektiven beseitigung der tumorzellen, die eine inaktivierte p53 pathway haben ATE262033T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999RM000580A IT1306187B1 (it) 1999-09-21 1999-09-21 Metodo per l'eradicazione selettiva di cellule tumorali aventi lafunzione di p53 inattiva.
PCT/IT2000/000373 WO2001021765A2 (en) 1999-09-21 2000-09-21 Method for the selective protection of proliferating normal cells and the selective eradication of tumor cells having an inactive p53 pathway

Publications (1)

Publication Number Publication Date
ATE262033T1 true ATE262033T1 (de) 2004-04-15

Family

ID=11406961

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00964630T ATE262033T1 (de) 1999-09-21 2000-09-21 Methode für die selektive protektion der proliferation der normalen zellen und der selektiven beseitigung der tumorzellen, die eine inaktivierte p53 pathway haben

Country Status (8)

Country Link
EP (1) EP1214397B1 (de)
AT (1) ATE262033T1 (de)
AU (1) AU7555000A (de)
CA (1) CA2385424A1 (de)
DE (1) DE60009098T2 (de)
ES (1) ES2218224T3 (de)
IT (1) IT1306187B1 (de)
WO (1) WO2001021765A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2003006060A1 (ja) * 2001-07-09 2004-10-28 協和醗酵工業株式会社 Sh3ドメイン結合阻害剤

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03500166A (ja) * 1987-06-19 1991-01-17 シラキューズ ユニバーシティ チトカラシンの精製方法および組成物
GB9518536D0 (en) * 1995-09-11 1995-11-08 Pharma Mar Sa Three new cytotoxic macrolides from a marine sponge

Also Published As

Publication number Publication date
EP1214397A2 (de) 2002-06-19
AU7555000A (en) 2001-04-24
DE60009098D1 (de) 2004-04-22
ITRM990580A0 (it) 1999-09-21
CA2385424A1 (en) 2001-03-29
ES2218224T3 (es) 2004-11-16
IT1306187B1 (it) 2001-05-30
EP1214397B1 (de) 2004-03-17
WO2001021765A3 (en) 2001-10-11
WO2001021765A2 (en) 2001-03-29
DE60009098T2 (de) 2005-03-24
ITRM990580A1 (it) 2001-03-21

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