ATE260102T1 - Benzamidin-derivate - Google Patents
Benzamidin-derivateInfo
- Publication number
- ATE260102T1 ATE260102T1 AT00979969T AT00979969T ATE260102T1 AT E260102 T1 ATE260102 T1 AT E260102T1 AT 00979969 T AT00979969 T AT 00979969T AT 00979969 T AT00979969 T AT 00979969T AT E260102 T1 ATE260102 T1 AT E260102T1
- Authority
- AT
- Austria
- Prior art keywords
- blood
- coagulation
- inhibiting
- benzamidine derivatives
- effect
- Prior art date
Links
- PXXJHWLDUBFPOL-UHFFFAOYSA-N benzamidine Chemical class NC(=N)C1=CC=CC=C1 PXXJHWLDUBFPOL-UHFFFAOYSA-N 0.000 title 1
- 230000023555 blood coagulation Effects 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 208000005189 Embolism Diseases 0.000 abstract 1
- 108010074860 Factor Xa Proteins 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000003937 benzamidines Chemical class 0.000 abstract 1
- 239000003130 blood coagulation factor inhibitor Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP34850499 | 1999-12-08 | ||
| PCT/JP2000/008656 WO2001042254A1 (fr) | 1999-12-08 | 2000-12-07 | Derives benzamidine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE260102T1 true ATE260102T1 (de) | 2004-03-15 |
Family
ID=18397469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00979969T ATE260102T1 (de) | 1999-12-08 | 2000-12-07 | Benzamidin-derivate |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6784191B2 (de) |
| EP (1) | EP1236735B1 (de) |
| JP (1) | JP4446145B2 (de) |
| AT (1) | ATE260102T1 (de) |
| AU (1) | AU1733101A (de) |
| DE (1) | DE60008584T2 (de) |
| WO (1) | WO2001042254A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4900238B2 (ja) * | 2005-02-02 | 2012-03-21 | 味の素株式会社 | 新規ベンズアミジン化合物 |
| SG10201605495UA (en) * | 2011-07-05 | 2016-09-29 | Becton Dickinson Co | Coagulation controlling agents and devices comprising the same |
| CN103933488A (zh) * | 2013-01-17 | 2014-07-23 | 赵明义 | 用于治疗脑血栓的配方 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5952307A (en) * | 1994-01-21 | 1999-09-14 | Georgia Tech Research Corp. | Basic α-aminoalkylphosphonate derivatives |
| JPH11140040A (ja) * | 1997-11-06 | 1999-05-25 | Kissei Pharmaceut Co Ltd | ３−アミジノフェニルエーテル誘導体、活性化血液凝固第ｘ因子阻害剤およびそれらの製造中間体 |
| DE69839246T2 (de) | 1997-12-12 | 2009-03-19 | Sony Corp. | Optische platte aufzeichnungs/wiedergabeverfahren, optische platte und optischeplattenvorrichtung |
| KR20010052694A (ko) * | 1998-06-08 | 2001-06-25 | 에가시라 구니오 | 벤즈아미딘 유도체 |
| AU1651201A (en) * | 1999-12-06 | 2001-06-18 | Ajinomoto Co., Inc. | Amidinophenylpyruvic acid derivative |
-
2000
- 2000-12-07 EP EP00979969A patent/EP1236735B1/de not_active Expired - Lifetime
- 2000-12-07 JP JP2001543552A patent/JP4446145B2/ja not_active Expired - Fee Related
- 2000-12-07 DE DE60008584T patent/DE60008584T2/de not_active Expired - Lifetime
- 2000-12-07 AU AU17331/01A patent/AU1733101A/en not_active Abandoned
- 2000-12-07 WO PCT/JP2000/008656 patent/WO2001042254A1/ja active IP Right Grant
- 2000-12-07 AT AT00979969T patent/ATE260102T1/de not_active IP Right Cessation
-
2002
- 2002-06-10 US US10/164,623 patent/US6784191B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU1733101A (en) | 2001-06-18 |
| JP4446145B2 (ja) | 2010-04-07 |
| EP1236735A4 (de) | 2002-10-29 |
| EP1236735B1 (de) | 2004-02-25 |
| DE60008584D1 (de) | 2004-04-01 |
| EP1236735A1 (de) | 2002-09-04 |
| US20020193348A1 (en) | 2002-12-19 |
| WO2001042254A1 (fr) | 2001-06-14 |
| US6784191B2 (en) | 2004-08-31 |
| DE60008584T2 (de) | 2004-11-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |