ATE258986T1 - Sekretorischer rekombinanter bcg impfstoff gegen aids - Google Patents

Sekretorischer rekombinanter bcg impfstoff gegen aids

Info

Publication number
ATE258986T1
ATE258986T1 AT95926523T AT95926523T ATE258986T1 AT E258986 T1 ATE258986 T1 AT E258986T1 AT 95926523 T AT95926523 T AT 95926523T AT 95926523 T AT95926523 T AT 95926523T AT E258986 T1 ATE258986 T1 AT E258986T1
Authority
AT
Austria
Prior art keywords
antigen
fused protein
alpha
bcg
vaccine against
Prior art date
Application number
AT95926523T
Other languages
English (en)
Inventor
Kazuhiro Matsuo
Yoshitomo Chujo
Akihiro Yamazaki
Mitsuo Honda
Shudo Yamazaki
Hiromichi Tasaka
Original Assignee
Ajinomoto Kk
Agency Nat Inst Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk, Agency Nat Inst Health filed Critical Ajinomoto Kk
Application granted granted Critical
Publication of ATE258986T1 publication Critical patent/ATE258986T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/473—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used alpha-Glycoproteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
    • C12N15/03—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT95926523T 1994-07-29 1995-07-31 Sekretorischer rekombinanter bcg impfstoff gegen aids ATE258986T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP17846294 1994-07-29
PCT/JP1995/001515 WO1996004009A1 (fr) 1994-07-29 1995-07-31 Vaccin b.c.g. de recombinaison secretoire contre le sida

Publications (1)

Publication Number Publication Date
ATE258986T1 true ATE258986T1 (de) 2004-02-15

Family

ID=16048947

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95926523T ATE258986T1 (de) 1994-07-29 1995-07-31 Sekretorischer rekombinanter bcg impfstoff gegen aids

Country Status (6)

Country Link
EP (1) EP0745386B1 (de)
KR (1) KR100217809B1 (de)
CN (1) CN1136280A (de)
AT (1) ATE258986T1 (de)
DE (1) DE69532524D1 (de)
WO (1) WO1996004009A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0917866A1 (de) 1997-11-12 1999-05-26 The Procter & Gamble Company Damenbinde mit einem gestuften Klebestreifen
JP2002114708A (ja) * 2000-10-06 2002-04-16 Puraimyuun Corporation:Kk Ｄｎａワチンに対するアジュバント剤
ES2370885T3 (es) * 2004-12-01 2011-12-23 Aeras Global Tuberculosis Vaccine Foundation Electroporación de mycobacterium y sobreexpresión de antígenos en micobacterias.
CN101456905B (zh) * 2008-12-05 2013-01-16 中国科学院海洋研究所 一种细菌五型分泌蛋白及其构建方法和应用
CN103497926B (zh) * 2013-10-21 2016-02-10 深圳大学 表达分泌人类p53蛋白的重组BCG活菌菌株、活菌疫苗及其构建方法和应用
CN108823232A (zh) * 2018-04-20 2018-11-16 中国科学院广州生物医药与健康研究院 一种艾滋病疫苗及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2903414B2 (ja) * 1989-05-31 1999-06-07 味の素株式会社 抗酸菌分泌発現ベクター及び抗酸菌
EP0400973B1 (de) * 1989-05-31 1996-07-31 Ajinomoto Co., Inc. Sekretorische Expressionsvektoren für Mycobakterien sowie Transformanten

Also Published As

Publication number Publication date
EP0745386B1 (de) 2004-02-04
CN1136280A (zh) 1996-11-20
EP0745386A1 (de) 1996-12-04
DE69532524D1 (de) 2004-03-11
KR960704570A (ko) 1996-10-09
WO1996004009A1 (fr) 1996-02-15
EP0745386A4 (de) 1999-07-14
KR100217809B1 (ko) 1999-09-01

Similar Documents

Publication Publication Date Title
ATE70717T1 (de) Vermehrung der antigenimmunogenizitaet.
PT88329A (pt) Bacterias nao virulentas contra infeccoes estreptococicas
DE69838383D1 (de) Kulturmedium mit sojabohnenextrakt als aminosäuren-quelle und ohne proteinkomplexe tierischen ursprungs
DE69019609D1 (de) Proteine und deren Herstellung.
ATE132195T1 (de) Rekombinant-mykobakterielle impfstoffe
IL102687A (en) Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them
CA2079463A1 (en) Live vaccines
DK0732937T3 (da) Ikke-toxisk slimhindeadjuvans
WO2001096368A3 (en) Use of coiled-coil structural scaffold to generate structure-specific peptides
DK371087D0 (da) Mamalialt interleukin-4
ES531986A0 (es) Un metodo de producir una forma geneticamente estable de vidrio cholerae
ES2196155T3 (es) Pprocedimientos para inducir la produccion de anticuerpos contra las bacterias de la familia cs4-cfa/1 de e. coli.
ATE258986T1 (de) Sekretorischer rekombinanter bcg impfstoff gegen aids
DE69737413D1 (en) Bakterioferritin aus helicobacter pylori
ATE457352T1 (de) Subtilisin-carlsberg-proteine mit verminderter immunogenität
CA2089753A1 (en) Interleukin-2-leukotoxin gene fusions and uses therefor
ATE302016T1 (de) Peptide, verwendet als träger in immunogenen konstrukten, die in der entwicklung synthetischer impfstoffe geeignet sind
ES2080024A1 (es) Vacuna subunitaria recombinante contra la enfermedad hemorragica virica de los conejos.
ES2081864T3 (es) Metodo para purificar una proteina de la membrana exterior de haemophilus influenzae.
ATE356217T1 (de) Rekombinante mikroorganismen
AU1321988A (en) The cloning of malaria-specific dna sequences: isolation of the gene for the 140 kd protein
Poff-Reichow Development of Brucella abortus RB51 as a Vaccine to Protect Against Brucellosis and Anthrax
DE68926294D1 (de) Antigen gegen diabetes
DE69128095D1 (de) Azelluläre impfstoffe
DK0575462T3 (da) Fremgangsmåde til fremstilling af chymosin

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties