ATE256293T1 - Verfahren zur bilderzeugung mit magnetischer resonanz - Google Patents

Verfahren zur bilderzeugung mit magnetischer resonanz

Info

Publication number
ATE256293T1
ATE256293T1 AT98900104T AT98900104T ATE256293T1 AT E256293 T1 ATE256293 T1 AT E256293T1 AT 98900104 T AT98900104 T AT 98900104T AT 98900104 T AT98900104 T AT 98900104T AT E256293 T1 ATE256293 T1 AT E256293T1
Authority
AT
Austria
Prior art keywords
hyperpolarizable
imaging agent
gas
magnetic resonance
generating image
Prior art date
Application number
AT98900104T
Other languages
English (en)
Inventor
Jan Henrik Ardenkjaer-Larsen
Oskar Axelsson
Klaes Golman
Georg Hansson
Ib Leunbach
Stefan Pettersson
Lars Goeran Wistrand
Original Assignee
Amersham Health As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9700256.2A external-priority patent/GB9700256D0/en
Priority claimed from GBGB9724590.6A external-priority patent/GB9724590D0/en
Priority claimed from GBGB9725364.5A external-priority patent/GB9725364D0/en
Application filed by Amersham Health As filed Critical Amersham Health As
Application granted granted Critical
Publication of ATE256293T1 publication Critical patent/ATE256293T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent

Landscapes

  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • General Health & Medical Sciences (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Compounds Of Iron (AREA)
AT98900104T 1997-01-08 1998-01-05 Verfahren zur bilderzeugung mit magnetischer resonanz ATE256293T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9700256.2A GB9700256D0 (en) 1997-01-08 1997-01-08 Method
GBGB9724590.6A GB9724590D0 (en) 1997-11-20 1997-11-20 Method
GBGB9725364.5A GB9725364D0 (en) 1997-11-28 1997-11-28 Method
PCT/GB1998/000021 WO1998030918A1 (en) 1997-01-08 1998-01-05 Method of magnetic resonance imaging

Publications (1)

Publication Number Publication Date
ATE256293T1 true ATE256293T1 (de) 2003-12-15

Family

ID=27268659

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98900104T ATE256293T1 (de) 1997-01-08 1998-01-05 Verfahren zur bilderzeugung mit magnetischer resonanz

Country Status (7)

Country Link
US (1) US6453188B1 (de)
EP (1) EP0951650B1 (de)
JP (1) JP2001513661A (de)
AT (1) ATE256293T1 (de)
AU (1) AU5335298A (de)
DE (1) DE69820415T2 (de)
WO (1) WO1998030918A1 (de)

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US5545396A (en) * 1994-04-08 1996-08-13 The Research Foundation Of State University Of New York Magnetic resonance imaging using hyperpolarized noble gases
RU2186405C2 (ru) * 1996-03-29 2002-07-27 Лоренс Беркли Нэшнл Лэборэтори Усиление ядерного магнитного резонанса (ямр) и магниторезонансной визуализации (мрв) в присутствии гиперполяризованных благородных газов
US8765099B2 (en) * 1996-04-08 2014-07-01 Koninklijke Philips N.V. Magnetic resonance imaging hyperpolarization of liquids or solids by light with orbital angular momentum
US6278893B1 (en) * 1998-01-05 2001-08-21 Nycomed Imaging As Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent
FI105447B (fi) * 1998-11-03 2000-08-31 Raimo Pentti Juhani Joensuu Järjestely kohteen tutkimiseen
GB9828853D0 (en) * 1998-12-30 1999-02-17 Nycomed Amersham Plc Nmr spectroscopy method
GB9911681D0 (en) * 1999-05-19 1999-07-21 Nycomed Imaging As Process
US6408849B1 (en) * 1999-06-18 2002-06-25 Aeronex, Inc. Recovery and purification of gases used in medical processes
US6338836B1 (en) 1999-09-28 2002-01-15 Siemens Aktiengesellschaft Asthma analysis method employing hyperpolarized gas and magnetic resonance imaging
US6630126B2 (en) * 2000-03-13 2003-10-07 Medi-Physics, Inc. Diagnostic procedures using direct injection of gaseous hyperpolarized 129Xe and associated systems and products
US6845262B2 (en) 2000-03-29 2005-01-18 The Brigham And Women's Hospital, Inc. Low-field MRI
GB0009353D0 (en) * 2000-04-14 2000-05-31 Nycomed Imaging As Method
US7850152B2 (en) 2001-04-24 2010-12-14 Medi Physics, Inc. Methods and devices for moisturizing hyperpolarized noble gases and associated moisturized pharmaceutical grade inhalable hyperpolarized gas products
US7126332B2 (en) * 2001-07-20 2006-10-24 Baker Hughes Incorporated Downhole high resolution NMR spectroscopy with polarization enhancement
GB0122049D0 (en) * 2001-09-12 2001-10-31 Nycomed Imaging As Method
JP2007508092A (ja) * 2003-10-13 2007-04-05 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 磁気共鳴画像化システム及び方法
PL1824523T3 (pl) * 2004-11-19 2013-12-31 Ge Healthcare As Sposób obrazowania serca przy zastosowaniu hiperspolaryzowanego 13C-pirogronianu
JP4696262B2 (ja) * 2005-05-18 2011-06-08 独立行政法人産業技術総合研究所 超偏極希ガス製造装置及び超偏極希ガスを用いた核磁気共鳴分光装置並びに磁気共鳴イメージング装置
JP2007021008A (ja) * 2005-07-20 2007-02-01 Hitachi Ltd Ｄｎｐ過分極手段を備えた磁気共鳴イメージング装置
US20070025918A1 (en) * 2005-07-28 2007-02-01 General Electric Company Magnetic resonance imaging (MRI) agents: water soluble carbon-13 enriched fullerene and carbon nanotubes for use with dynamic nuclear polarization
WO2007038626A2 (en) * 2005-09-28 2007-04-05 President And Fellows Of Harvard College Hyperpolarized solid materials with long spin relaxation times for use as imaging agents in magnetic resonance imaging
ES2654520T3 (es) * 2005-10-11 2018-02-14 Huntington Medical Research Institutes Agentes de formación de imágenes y métodos de uso de los mismos
AU2006326596A1 (en) * 2005-12-10 2007-06-21 The President And Fellows Of Harvard College In situ hyperpolarization of imaging agents
US20090252686A1 (en) * 2006-01-11 2009-10-08 President And Fellows Of Harvard College Ex Vivo Hyperpolarization of Imaging Agents
US8703102B2 (en) * 2008-04-04 2014-04-22 Millikelvin Technologies Llc Systems and methods for producing hyperpolarized materials and mixtures thereof
US9207298B2 (en) 2011-03-23 2015-12-08 Millikelvin Technologies Llc Techniques, systems and machine readable programs for magnetic resonance
AU2007254464B2 (en) * 2006-02-21 2013-02-21 Avrum Belzer Hyperpolarization methods, systems and compositions
WO2007149454A2 (en) * 2006-06-19 2007-12-27 Beth Isreal Deaconess Medical Center, Inc. Imaging agents for use in magnetic resonance blood flow/perfusion imaging
EP2117607A4 (de) 2007-01-11 2012-08-08 Huntington Medical Res Inst Abbildungswirkstoffe und verfahren zu ihrer verwendung
WO2009046457A2 (en) * 2007-10-05 2009-04-09 Huntington Medical Research Institutes Imaging of genetic material with magnetic resonance
FR2924826B1 (fr) * 2007-12-11 2010-03-05 Commissariat Energie Atomique Horloge atomique a correction du champ magnetique ambiant
EP2902041A1 (de) * 2007-12-19 2015-08-05 GE Healthcare Limited Zusammensetzung und Verfahren zur Erzeugung eines metabolischen Profils bei Verwendung von 13C-MR
WO2009129265A1 (en) * 2008-04-14 2009-10-22 Huntington Medical Research Institutes Methods and apparatus for pasadena hyperpolarization
WO2009133169A1 (en) 2008-05-02 2009-11-05 General Electric Company Method of determining alanine transaminase (alt) activity by 13c-mr detection using hyperpolarised 13c-pyruvate
EP2315883A4 (de) 2008-06-06 2014-07-09 Bayer Medical Care Inc Vorrichtungen und verfahren zur verabreichung von flüssigkeitsinjektionsboli an patienten und handhabung von schädlichen flüssigkeiten
US9289518B2 (en) * 2008-08-22 2016-03-22 The Brigham And Women's Hospital Enhanced 13C NMR by thermal mixing with hyperpolarized 129XE
US20100092390A1 (en) * 2008-10-09 2010-04-15 President And Fellows Of Harvard College Methods for Making Particles Having Long Spin-Lattice Relaxation Times
BRPI1013677A2 (pt) 2009-04-02 2016-04-26 Ge Healthcare Ltd método para detectar inflamação ou infecção, e, usos de um 13c-piruvato hiperpolarizado, e de um meio de formação de imagem.
EP2443444A1 (de) * 2009-06-19 2012-04-25 Koninklijke Philips Electronics N.V. Mri-thermometrie in kombination mit einer hyperpolarisationsvorrichtung mit photonen mit bahndrehimpuls
US20120150019A1 (en) * 2009-08-11 2012-06-14 Koninklijke Philips Electronics N.V. Mri by direct transverse hyperpolarization using light endowed with orbital angular momentum
SG178927A1 (en) * 2009-08-31 2012-04-27 Millikelvin Technologies Llc Systems and methods for producing hyperpolarized materials and mixtures thereof
EP2476009A1 (de) 2009-09-10 2012-07-18 GE Healthcare UK Limited 13c-mr-detektion mit hyperpolarisierter 13-c-fructose
US8970217B1 (en) 2010-04-14 2015-03-03 Hypres, Inc. System and method for noise reduction in magnetic resonance imaging
AU2011250012B2 (en) 2010-05-03 2016-02-25 Ge Healthcare Limited Hyperpolarized lactate contrast agent for determination of LDH activity
US9714995B2 (en) 2011-03-23 2017-07-25 Millikelvin Technologies Llc Techniques, systems and machine readable programs for magnetic resonance
US9889288B2 (en) 2012-06-07 2018-02-13 Bayer Healthcare Llc Tubing connectors
US9393441B2 (en) 2012-06-07 2016-07-19 Bayer Healthcare Llc Radiopharmaceutical delivery and tube management system
US9125976B2 (en) 2012-06-07 2015-09-08 Bayer Medical Care Inc. Shield adapters
EP2863229A1 (de) 2013-10-15 2015-04-22 Technische Universität München pH-Biosensoren auf Basis von Verbindungen mit pH-sensiblen Enolgruppen zur Magnetresonanzbildgebung und Spektroskopie und deren Verwendungen
EP2891500B1 (de) 2014-01-07 2018-08-01 Cambridge Enterprise Limited Kontrastmittel zur Bestimmung von Aldehyd-Dehydrogenase-(ALDH)-Aktivität
EP3015855A1 (de) 2014-10-27 2016-05-04 Klinikum rechts der Isar der Technischen Universität München Metall-Biosensoren auf Basis von Verbindungen mit metallempfindlichen chemischen Verschiebungen für magnetische Resonanzspektroskopie und Magnetresonanzbildgebung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5545396A (en) * 1994-04-08 1996-08-13 The Research Foundation Of State University Of New York Magnetic resonance imaging using hyperpolarized noble gases
USH1968H1 (en) * 1995-06-07 2001-06-05 General Electric Company Hyperpolarized MR imaging using pulse sequence with progressively increasing flip angle
US5617859A (en) * 1995-10-02 1997-04-08 General Electric Company Apparatus and methods for magnetic resonance (MR) imaging of cavities using fluids polarized at low temperatures
US6278893B1 (en) * 1998-01-05 2001-08-21 Nycomed Imaging As Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent

Also Published As

Publication number Publication date
AU5335298A (en) 1998-08-03
US6453188B1 (en) 2002-09-17
EP0951650A1 (de) 1999-10-27
JP2001513661A (ja) 2001-09-04
DE69820415D1 (de) 2004-01-22
WO1998030918A1 (en) 1998-07-16
EP0951650B1 (de) 2003-12-10
DE69820415T2 (de) 2004-09-16

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