ATE256293T1 - Verfahren zur bilderzeugung mit magnetischer resonanz - Google Patents
Verfahren zur bilderzeugung mit magnetischer resonanzInfo
- Publication number
- ATE256293T1 ATE256293T1 AT98900104T AT98900104T ATE256293T1 AT E256293 T1 ATE256293 T1 AT E256293T1 AT 98900104 T AT98900104 T AT 98900104T AT 98900104 T AT98900104 T AT 98900104T AT E256293 T1 ATE256293 T1 AT E256293T1
- Authority
- AT
- Austria
- Prior art keywords
- hyperpolarizable
- imaging agent
- gas
- magnetic resonance
- generating image
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
Landscapes
- Physics & Mathematics (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Signal Processing (AREA)
- General Health & Medical Sciences (AREA)
- High Energy & Nuclear Physics (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- General Physics & Mathematics (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Compounds Of Iron (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9700256.2A GB9700256D0 (en) | 1997-01-08 | 1997-01-08 | Method |
GBGB9724590.6A GB9724590D0 (en) | 1997-11-20 | 1997-11-20 | Method |
GBGB9725364.5A GB9725364D0 (en) | 1997-11-28 | 1997-11-28 | Method |
PCT/GB1998/000021 WO1998030918A1 (en) | 1997-01-08 | 1998-01-05 | Method of magnetic resonance imaging |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE256293T1 true ATE256293T1 (de) | 2003-12-15 |
Family
ID=27268659
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98900104T ATE256293T1 (de) | 1997-01-08 | 1998-01-05 | Verfahren zur bilderzeugung mit magnetischer resonanz |
Country Status (7)
Country | Link |
---|---|
US (1) | US6453188B1 (de) |
EP (1) | EP0951650B1 (de) |
JP (1) | JP2001513661A (de) |
AT (1) | ATE256293T1 (de) |
AU (1) | AU5335298A (de) |
DE (1) | DE69820415T2 (de) |
WO (1) | WO1998030918A1 (de) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5545396A (en) * | 1994-04-08 | 1996-08-13 | The Research Foundation Of State University Of New York | Magnetic resonance imaging using hyperpolarized noble gases |
BR9711082A (pt) * | 1996-03-29 | 2000-01-11 | Lawrence Berkeley National Lab | Realce de rmn emri na presença de gases mopbres hiperpolarizados. |
US8765099B2 (en) * | 1996-04-08 | 2014-07-01 | Koninklijke Philips N.V. | Magnetic resonance imaging hyperpolarization of liquids or solids by light with orbital angular momentum |
US6278893B1 (en) | 1998-01-05 | 2001-08-21 | Nycomed Imaging As | Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent |
FI105447B (fi) * | 1998-11-03 | 2000-08-31 | Raimo Pentti Juhani Joensuu | Järjestely kohteen tutkimiseen |
GB9828853D0 (en) * | 1998-12-30 | 1999-02-17 | Nycomed Amersham Plc | Nmr spectroscopy method |
GB9911681D0 (en) * | 1999-05-19 | 1999-07-21 | Nycomed Imaging As | Process |
US6408849B1 (en) * | 1999-06-18 | 2002-06-25 | Aeronex, Inc. | Recovery and purification of gases used in medical processes |
US6338836B1 (en) | 1999-09-28 | 2002-01-15 | Siemens Aktiengesellschaft | Asthma analysis method employing hyperpolarized gas and magnetic resonance imaging |
EP1265527A2 (de) * | 2000-03-13 | 2002-12-18 | Medi-Physics, Inc. | Diagnostische verfahren unter verwendung direkter injizierung von gasförmigem hyperpolarisiertem 129 xenon |
US6845262B2 (en) | 2000-03-29 | 2005-01-18 | The Brigham And Women's Hospital, Inc. | Low-field MRI |
GB0009353D0 (en) * | 2000-04-14 | 2000-05-31 | Nycomed Imaging As | Method |
EP1387700A2 (de) * | 2001-04-24 | 2004-02-11 | Medi-Physics, Inc. | Verfahren und geräte zur befeuchtung hyperpolarisierten edelgasen insbesondere in arzneimitteln |
US7126332B2 (en) * | 2001-07-20 | 2006-10-24 | Baker Hughes Incorporated | Downhole high resolution NMR spectroscopy with polarization enhancement |
GB0122049D0 (en) * | 2001-09-12 | 2001-10-31 | Nycomed Imaging As | Method |
CN1867835B (zh) * | 2003-10-13 | 2010-06-16 | 皇家飞利浦电子股份有限公司 | 磁共振成像系统和方法 |
WO2006054903A2 (en) * | 2004-11-19 | 2006-05-26 | Ge Healthcare As | Method of cardiac imaging with the use of hyperpolarized 13 c-pyruvate |
JP4696262B2 (ja) * | 2005-05-18 | 2011-06-08 | 独立行政法人産業技術総合研究所 | 超偏極希ガス製造装置及び超偏極希ガスを用いた核磁気共鳴分光装置並びに磁気共鳴イメージング装置 |
JP2007021008A (ja) * | 2005-07-20 | 2007-02-01 | Hitachi Ltd | Dnp過分極手段を備えた磁気共鳴イメージング装置 |
US20070025918A1 (en) * | 2005-07-28 | 2007-02-01 | General Electric Company | Magnetic resonance imaging (MRI) agents: water soluble carbon-13 enriched fullerene and carbon nanotubes for use with dynamic nuclear polarization |
JP2009510081A (ja) * | 2005-09-28 | 2009-03-12 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 磁気共鳴イメージングにおける造影剤としての使用のための長いスピン緩和時間を有する過分極化された固形物 |
WO2007044867A2 (en) * | 2005-10-11 | 2007-04-19 | Huntington Medical Research Institutes | Imaging agents and methods of use thereof |
WO2007070466A2 (en) * | 2005-12-10 | 2007-06-21 | The President And Fellows Of Harvard College | In situ hyperpolarization of imaging agents |
JP2009523172A (ja) * | 2006-01-11 | 2009-06-18 | プレジデント・アンド・フエローズ・オブ・ハーバード・カレツジ | 造影剤のエクスビボ過分極 |
US9207298B2 (en) * | 2011-03-23 | 2015-12-08 | Millikelvin Technologies Llc | Techniques, systems and machine readable programs for magnetic resonance |
US8703102B2 (en) * | 2008-04-04 | 2014-04-22 | Millikelvin Technologies Llc | Systems and methods for producing hyperpolarized materials and mixtures thereof |
WO2007136439A2 (en) * | 2006-02-21 | 2007-11-29 | Avrum Belzer | Hyperpolarization methods, systems and compositions |
US8623327B2 (en) * | 2006-06-19 | 2014-01-07 | Beth Israel Deaconess Medical Center, Inc. | Imaging agents for use in magnetic resonance blood flow/perfusion imaging |
US20100092391A1 (en) * | 2007-01-11 | 2010-04-15 | Huntington Medical Research Institutes | Imaging agents and methods of use thereof |
US20100233089A1 (en) * | 2007-10-05 | 2010-09-16 | Huntington Medical Research Institutes | Imaging of genetic material with magnetic resonance |
FR2924826B1 (fr) * | 2007-12-11 | 2010-03-05 | Commissariat Energie Atomique | Horloge atomique a correction du champ magnetique ambiant |
EP2072061A1 (de) | 2007-12-19 | 2009-06-24 | GE Healthcare Limited | Zusammensetzung und Verfahren zur Erzeugung eines metabolischen Profils bei Verwendung von 13C-MR |
WO2009129265A1 (en) * | 2008-04-14 | 2009-10-22 | Huntington Medical Research Institutes | Methods and apparatus for pasadena hyperpolarization |
US20110038802A1 (en) | 2008-05-02 | 2011-02-17 | Zhong-Min Hu | Method of determining alanine transaminase (alt) activity by 13c-mr detection using hyperpolarised 13c-pyruvate |
US9056200B2 (en) * | 2008-06-06 | 2015-06-16 | Bayer Medical Care Inc. | Apparatus and methods for delivery of fluid injection boluses to patients and handling harmful fluids |
US9289518B2 (en) * | 2008-08-22 | 2016-03-22 | The Brigham And Women's Hospital | Enhanced 13C NMR by thermal mixing with hyperpolarized 129XE |
US20100092390A1 (en) * | 2008-10-09 | 2010-04-15 | President And Fellows Of Harvard College | Methods for Making Particles Having Long Spin-Lattice Relaxation Times |
CN102388317B (zh) | 2009-04-02 | 2015-11-25 | 通用电气健康护理有限公司 | 包含超极化13c丙酮酸盐的磁共振成像介质用于检测炎症或感染的用途 |
WO2010146517A1 (en) * | 2009-06-19 | 2010-12-23 | Koninklijke Philips Electronics N.V. | Mri thermometry combined with hyperpolarisation device using photons with orbital angular momentum |
US20120150019A1 (en) * | 2009-08-11 | 2012-06-14 | Koninklijke Philips Electronics N.V. | Mri by direct transverse hyperpolarization using light endowed with orbital angular momentum |
CA2772190A1 (en) * | 2009-08-31 | 2011-03-03 | Millikelvin Technologies Llc | Systems and methods for producing hyperpolarized materials and mixtures thereof |
US8968703B2 (en) | 2009-09-10 | 2015-03-03 | Ge Healthcare Limited | 13C-MR detection using hyperpolarised 13C-fructose |
US8970217B1 (en) | 2010-04-14 | 2015-03-03 | Hypres, Inc. | System and method for noise reduction in magnetic resonance imaging |
WO2011138269A1 (en) | 2010-05-03 | 2011-11-10 | Ge Healthcare Limited | Hyperpolarized lactate contrast agent for determination of ldh activity |
US9714995B2 (en) | 2011-03-23 | 2017-07-25 | Millikelvin Technologies Llc | Techniques, systems and machine readable programs for magnetic resonance |
US9125976B2 (en) | 2012-06-07 | 2015-09-08 | Bayer Medical Care Inc. | Shield adapters |
US9889288B2 (en) | 2012-06-07 | 2018-02-13 | Bayer Healthcare Llc | Tubing connectors |
US9393441B2 (en) | 2012-06-07 | 2016-07-19 | Bayer Healthcare Llc | Radiopharmaceutical delivery and tube management system |
EP2863229A1 (de) | 2013-10-15 | 2015-04-22 | Technische Universität München | pH-Biosensoren auf Basis von Verbindungen mit pH-sensiblen Enolgruppen zur Magnetresonanzbildgebung und Spektroskopie und deren Verwendungen |
EP2891500B1 (de) | 2014-01-07 | 2018-08-01 | Cambridge Enterprise Limited | Kontrastmittel zur Bestimmung von Aldehyd-Dehydrogenase-(ALDH)-Aktivität |
EP3015855A1 (de) | 2014-10-27 | 2016-05-04 | Klinikum rechts der Isar der Technischen Universität München | Metall-Biosensoren auf Basis von Verbindungen mit metallempfindlichen chemischen Verschiebungen für magnetische Resonanzspektroskopie und Magnetresonanzbildgebung |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5545396A (en) * | 1994-04-08 | 1996-08-13 | The Research Foundation Of State University Of New York | Magnetic resonance imaging using hyperpolarized noble gases |
USH1968H1 (en) * | 1995-06-07 | 2001-06-05 | General Electric Company | Hyperpolarized MR imaging using pulse sequence with progressively increasing flip angle |
US5617859A (en) * | 1995-10-02 | 1997-04-08 | General Electric Company | Apparatus and methods for magnetic resonance (MR) imaging of cavities using fluids polarized at low temperatures |
US6278893B1 (en) * | 1998-01-05 | 2001-08-21 | Nycomed Imaging As | Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent |
-
1998
- 1998-01-05 JP JP53062798A patent/JP2001513661A/ja active Pending
- 1998-01-05 AT AT98900104T patent/ATE256293T1/de not_active IP Right Cessation
- 1998-01-05 DE DE69820415T patent/DE69820415T2/de not_active Expired - Fee Related
- 1998-01-05 AU AU53352/98A patent/AU5335298A/en not_active Abandoned
- 1998-01-05 WO PCT/GB1998/000021 patent/WO1998030918A1/en active IP Right Grant
- 1998-01-05 EP EP98900104A patent/EP0951650B1/de not_active Expired - Lifetime
-
1999
- 1999-06-16 US US09/333,910 patent/US6453188B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2001513661A (ja) | 2001-09-04 |
DE69820415D1 (de) | 2004-01-22 |
AU5335298A (en) | 1998-08-03 |
US6453188B1 (en) | 2002-09-17 |
DE69820415T2 (de) | 2004-09-16 |
EP0951650B1 (de) | 2003-12-10 |
EP0951650A1 (de) | 1999-10-27 |
WO1998030918A1 (en) | 1998-07-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |