ATE225518T1 - Verfahren zur elektronspinresonanz-verstärkten magnetresonanzabbildung (esremri) mit dynamischer ex vivo kernpolarisation einer magnetresonanzabbildungssubstanz - Google Patents

Verfahren zur elektronspinresonanz-verstärkten magnetresonanzabbildung (esremri) mit dynamischer ex vivo kernpolarisation einer magnetresonanzabbildungssubstanz

Info

Publication number
ATE225518T1
ATE225518T1 AT97930621T AT97930621T ATE225518T1 AT E225518 T1 ATE225518 T1 AT E225518T1 AT 97930621 T AT97930621 T AT 97930621T AT 97930621 T AT97930621 T AT 97930621T AT E225518 T1 ATE225518 T1 AT E225518T1
Authority
AT
Austria
Prior art keywords
magnetic resonance
resonance imaging
esremri
dynamic
electron spin
Prior art date
Application number
AT97930621T
Other languages
English (en)
Inventor
Ib Leunbach
Ian Young
Goesta Ehnholm
Georg Hansson
Stefan Petersson
Lars-Goran Wistrand
Klaes Golman
Original Assignee
Amersham Health As
Picker Nordstar Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham Health As, Picker Nordstar Oy filed Critical Amersham Health As
Application granted granted Critical
Publication of ATE225518T1 publication Critical patent/ATE225518T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/282—Means specially adapted for hyperpolarisation or for hyperpolarised contrast agents, e.g. for the generation of hyperpolarised gases using optical pumping cells, for storing hyperpolarised contrast agents or for the determination of the polarisation of a hyperpolarised contrast agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/62—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using double resonance

Landscapes

  • Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Semiconductor Lasers (AREA)
AT97930621T 1996-07-05 1997-07-03 Verfahren zur elektronspinresonanz-verstärkten magnetresonanzabbildung (esremri) mit dynamischer ex vivo kernpolarisation einer magnetresonanzabbildungssubstanz ATE225518T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9614139.5A GB9614139D0 (en) 1996-07-05 1996-07-05 Method
PCT/GB1997/001804 WO1998001766A1 (en) 1996-07-05 1997-07-03 Method of electron spin resonance enhanced magnetic resonance imaging (esremri) with ex vivo dynamic nuclear polarisaton of an mr imaging agent

Publications (1)

Publication Number Publication Date
ATE225518T1 true ATE225518T1 (de) 2002-10-15

Family

ID=10796408

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97930621T ATE225518T1 (de) 1996-07-05 1997-07-03 Verfahren zur elektronspinresonanz-verstärkten magnetresonanzabbildung (esremri) mit dynamischer ex vivo kernpolarisation einer magnetresonanzabbildungssubstanz

Country Status (9)

Country Link
US (1) US6008644A (de)
EP (1) EP0909392B1 (de)
JP (1) JP4109719B2 (de)
AT (1) ATE225518T1 (de)
AU (1) AU3450497A (de)
DE (1) DE69716069T2 (de)
ES (1) ES2187794T3 (de)
GB (1) GB9614139D0 (de)
WO (1) WO1998001766A1 (de)

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GB9706282D0 (en) * 1997-03-26 1997-05-14 Nycomed Imaging As Method
AU8119298A (en) * 1997-06-19 1999-01-04 Nycomed Imaging As Overhauser magnetic resonance imaging (ormi) method comprising ex vivo polarization of a magnetic resonance (mr) imaging agent
US6278893B1 (en) 1998-01-05 2001-08-21 Nycomed Imaging As Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent
DE19911043A1 (de) * 1999-03-12 2000-09-14 Philips Corp Intellectual Pty MR-Verfahren
GB9911679D0 (en) * 1999-05-19 1999-07-21 Nycomed Imaging As Magnetic resonance imaging
US6318146B1 (en) 1999-07-14 2001-11-20 Wisconsin Alumni Research Foundation Multi-imaging modality tissue mimicking materials for imaging phantoms
GB0006207D0 (en) 2000-03-16 2000-05-03 Picker Nordstar Oy Nuclear magnetic resonance apparatus and method
US20040067591A1 (en) * 2002-10-04 2004-04-08 Wisconsin Alumni Research Foundation Tissue mimicking elastography phantoms
US7370656B2 (en) * 2003-04-15 2008-05-13 Koninklijke Philips Electronics N.V. Method and arrangement for influencing magnetic particles and detecting interfering material
EP1886278B1 (de) * 2004-12-14 2018-02-21 Philips Intellectual Property & Standards GmbH Verfahren zur bestimmung der räumlichen verteilung von magnetpartikeln
US20070025918A1 (en) * 2005-07-28 2007-02-01 General Electric Company Magnetic resonance imaging (MRI) agents: water soluble carbon-13 enriched fullerene and carbon nanotubes for use with dynamic nuclear polarization
US20090264732A1 (en) * 2005-10-11 2009-10-22 Huntington Medical Research Institutes Imaging agents and methods of use thereof
AU2007254464B2 (en) 2006-02-21 2013-02-21 Avrum Belzer Hyperpolarization methods, systems and compositions
US8703102B2 (en) 2008-04-04 2014-04-22 Millikelvin Technologies Llc Systems and methods for producing hyperpolarized materials and mixtures thereof
US7205764B1 (en) * 2006-04-11 2007-04-17 Varian, Inc. Method and apparatus for increasing the detection sensitivity in a high resolution NMR analysis
EP2117607A4 (de) 2007-01-11 2012-08-08 Huntington Medical Res Inst Abbildungswirkstoffe und verfahren zu ihrer verwendung
US20100233089A1 (en) * 2007-10-05 2010-09-16 Huntington Medical Research Institutes Imaging of genetic material with magnetic resonance
WO2009129265A1 (en) * 2008-04-14 2009-10-22 Huntington Medical Research Institutes Methods and apparatus for pasadena hyperpolarization
DK2349350T3 (en) * 2008-10-03 2017-02-27 Bracco Imaging Spa PROCEDURE FOR PREPARING Aqueous SOLUTIONS OF HYPERPOLARIZED MOLECULES
KR20120101339A (ko) 2009-08-31 2012-09-13 밀리켈빈 테크놀로지스 엘엘씨 과분극 물질 및 그 혼합물의 제조용 시스템 및 제조방법
US8970217B1 (en) 2010-04-14 2015-03-03 Hypres, Inc. System and method for noise reduction in magnetic resonance imaging
WO2014009240A1 (en) 2012-07-13 2014-01-16 Bracco Imaging Spa Triarylmethyl radicals
US9874622B2 (en) 2013-09-27 2018-01-23 General Electric Company Hyperpolarized media transport vessel
ES2745529T3 (es) 2013-10-28 2020-03-02 Bracco Imaging Spa Procedimiento para la preparación de compuestos de carboxilato hiperpolarizado
US10126438B2 (en) 2014-09-19 2018-11-13 University Of Virginia Patent Foundation Systems and methods for polarized nuclear imaging and spectroscopy
US11754652B2 (en) 2016-09-15 2023-09-12 University Of Virginia Patent Foundation Systems and methods for polarized nuclear imaging and spectroscopy
US10520561B2 (en) 2017-09-27 2019-12-31 General Electric Company System and method for hyperpolarizing a substance and quenching radicals therein
US10942237B2 (en) 2019-05-07 2021-03-09 GE Precision Healthcare LLC System and method for hyperpolarizing a substance
CN117148233B (zh) * 2023-10-31 2024-01-12 中国科学院精密测量科学与技术创新研究院 一种针对esr非均匀展宽的弱磁测量装置与方法

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FI85193C (fi) * 1989-11-27 1992-03-10 Instrumentarium Oy Undersoekningsfoerfarande och - anordning.
GB9024528D0 (en) * 1990-11-12 1991-01-02 Instrumentarium Corp Improvements in and relating to magnetic resonance imaging
GB9216597D0 (en) * 1992-08-05 1992-09-16 British Tech Group Method of obtaining images representing the distribution of paramagnetic material in solution
US5479925A (en) * 1994-06-23 1996-01-02 General Electric Company Magnetic resonance (MR) angiography in a low-field imaging magnet
DE19600241C2 (de) * 1995-01-13 2002-08-01 Bruker Biospin Gmbh Verfahren und Vorrichtung zum Auffinden von Edelsteinen in einer umgebenden Substanz mittels magnetischer Kernresonanz
US5678548A (en) * 1995-07-20 1997-10-21 The United States Of America As Represented By The Department Of Health And Human Services System and method for performing in vivo imaging and oxymetry and FT microscopy by pulsed radiofrequency electron paramagnetic resonance

Also Published As

Publication number Publication date
AU3450497A (en) 1998-02-02
EP0909392B1 (de) 2002-10-02
WO1998001766A1 (en) 1998-01-15
DE69716069D1 (de) 2002-11-07
JP4109719B2 (ja) 2008-07-02
JP2000513979A (ja) 2000-10-24
DE69716069T2 (de) 2003-06-26
ES2187794T3 (es) 2003-06-16
US6008644A (en) 1999-12-28
GB9614139D0 (en) 1996-09-04
EP0909392A1 (de) 1999-04-21

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