ATE254287T1 - Verfahren zum nachweis beta-amyloid-reduzierenden-agenzien - Google Patents
Verfahren zum nachweis beta-amyloid-reduzierenden-agenzienInfo
- Publication number
- ATE254287T1 ATE254287T1 AT98911801T AT98911801T ATE254287T1 AT E254287 T1 ATE254287 T1 AT E254287T1 AT 98911801 T AT98911801 T AT 98911801T AT 98911801 T AT98911801 T AT 98911801T AT E254287 T1 ATE254287 T1 AT E254287T1
- Authority
- AT
- Austria
- Prior art keywords
- amyloid
- reducing agents
- beta
- detecting beta
- present
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4709—Amyloid plaque core protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/821,876 US6221670B1 (en) | 1997-03-21 | 1997-03-21 | Methods to identify β-amyloid reducing agents |
PCT/US1998/005363 WO1998043094A1 (en) | 1997-03-21 | 1998-03-19 | METHODS TO IDENTIFY β-AMYLOID REDUCING AGENTS |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE254287T1 true ATE254287T1 (de) | 2003-11-15 |
Family
ID=25234504
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98911801T ATE254287T1 (de) | 1997-03-21 | 1998-03-19 | Verfahren zum nachweis beta-amyloid-reduzierenden-agenzien |
Country Status (9)
Country | Link |
---|---|
US (1) | US6221670B1 (de) |
EP (1) | EP0970379B1 (de) |
JP (1) | JP2002508834A (de) |
AT (1) | ATE254287T1 (de) |
AU (1) | AU6567198A (de) |
CA (1) | CA2284261A1 (de) |
DE (1) | DE69819696T2 (de) |
ES (1) | ES2212277T3 (de) |
WO (1) | WO1998043094A1 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE343562T1 (de) * | 2000-03-23 | 2006-11-15 | Elan Pharm Inc | Verbindungen und verfahren zur behandlung der alzheimerschen krankheit |
US6992081B2 (en) | 2000-03-23 | 2006-01-31 | Elan Pharmaceuticals, Inc. | Compounds to treat Alzheimer's disease |
GB0010565D0 (en) * | 2000-05-02 | 2000-06-21 | Medical Res Council | Assay for acetylcholinesterase inhibitors |
PE20020276A1 (es) | 2000-06-30 | 2002-04-06 | Elan Pharm Inc | COMPUESTOS DE AMINA SUSTITUIDA COMO INHIBIDORES DE ß-SECRETASA PARA EL TRATAMIENTO DE ALZHEIMER |
US20030096864A1 (en) * | 2000-06-30 | 2003-05-22 | Fang Lawrence Y. | Compounds to treat alzheimer's disease |
US6846813B2 (en) * | 2000-06-30 | 2005-01-25 | Pharmacia & Upjohn Company | Compounds to treat alzheimer's disease |
CN1217920C (zh) | 2000-06-30 | 2005-09-07 | 艾兰制药公司 | 治疗早老性痴呆的化合物 |
MXPA04000140A (es) * | 2001-06-27 | 2004-06-03 | Elan Pharm Inc | Derivados de beta-hidroxiamina utiles en el tratamiento de enfermedad de alzheimer. |
US20070213407A1 (en) * | 2001-06-29 | 2007-09-13 | Elan Pharmaceuticals And Pharmacia & Upjohn Company Llc | Compounds to treat Alzheimer's disease |
US6846641B2 (en) * | 2002-04-23 | 2005-01-25 | Agy Therapeutics, Inc. | In vitro ischemia model |
CA2501945A1 (en) * | 2002-10-09 | 2004-04-22 | Rinat Neuroscience Corp. | Methods of treating alzheimer's disease using antibodies directed against amyloid beta peptide and compositions thereof |
EA016357B1 (ru) * | 2004-07-30 | 2012-04-30 | Ринат Ньюросайенс Корп. | Антитела, направленные против бета-амилоидного пептида, и способы их применения |
MY148086A (en) * | 2005-04-29 | 2013-02-28 | Rinat Neuroscience Corp | Antibodies directed against amyloid-beta peptide and methods using same |
CL2007002908A1 (es) | 2007-10-09 | 2008-05-30 | Univ Concepcion | Procedimiento electroquimico in vitro para evaluar capacidad neurotoxica de estructuras, principios activos y/o compuestos de interes en celulas vivas y que comprende medir y cuantificar los parametros electricos en membranas expuestas a dichos agreg |
EP2560008B1 (de) | 2011-08-18 | 2016-11-30 | Korea Institute of Science and Technology | Pharmazeutische Zusammensetzungen zum Verhindern oder Behandeln einer regenerativen Hirnerkrankung und Verfahren zum Screening davon |
US9638548B2 (en) | 2012-05-07 | 2017-05-02 | Infineon Technologies Ag | Output switching systems and methods for magnetic field sensors |
US10102992B2 (en) | 2014-02-25 | 2018-10-16 | Infineon Technologies Ag | Switching apparatus, switching system and switching method |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5385915A (en) | 1990-05-16 | 1995-01-31 | The Rockefeller University | Treatment of amyloidosis associated with Alzheimer disease using modulators of protein phosphorylation |
US5766846A (en) * | 1992-07-10 | 1998-06-16 | Athena Neurosciences | Methods of screening for compounds which inhibit soluble β-amyloid peptide production |
-
1997
- 1997-03-21 US US08/821,876 patent/US6221670B1/en not_active Expired - Lifetime
-
1998
- 1998-03-19 ES ES98911801T patent/ES2212277T3/es not_active Expired - Lifetime
- 1998-03-19 DE DE69819696T patent/DE69819696T2/de not_active Expired - Lifetime
- 1998-03-19 AU AU65671/98A patent/AU6567198A/en not_active Abandoned
- 1998-03-19 AT AT98911801T patent/ATE254287T1/de not_active IP Right Cessation
- 1998-03-19 EP EP98911801A patent/EP0970379B1/de not_active Expired - Lifetime
- 1998-03-19 WO PCT/US1998/005363 patent/WO1998043094A1/en active Search and Examination
- 1998-03-19 JP JP54579598A patent/JP2002508834A/ja not_active Ceased
- 1998-03-19 CA CA002284261A patent/CA2284261A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2284261A1 (en) | 1998-10-01 |
EP0970379A1 (de) | 2000-01-12 |
ES2212277T3 (es) | 2004-07-16 |
DE69819696T2 (de) | 2004-09-16 |
WO1998043094A1 (en) | 1998-10-01 |
EP0970379B1 (de) | 2003-11-12 |
AU6567198A (en) | 1998-10-20 |
US6221670B1 (en) | 2001-04-24 |
JP2002508834A (ja) | 2002-03-19 |
DE69819696D1 (de) | 2003-12-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |