ATE250457T1 - Chromatographische adsorbenden, die merkaptoheterozyklische liganden anwenden - Google Patents

Chromatographische adsorbenden, die merkaptoheterozyklische liganden anwenden

Info

Publication number
ATE250457T1
ATE250457T1 AT95919182T AT95919182T ATE250457T1 AT E250457 T1 ATE250457 T1 AT E250457T1 AT 95919182 T AT95919182 T AT 95919182T AT 95919182 T AT95919182 T AT 95919182T AT E250457 T1 ATE250457 T1 AT E250457T1
Authority
AT
Austria
Prior art keywords
mercaptoheterocyclic
ligands
chromatographic adsorbents
cr1r2
nch3
Prior art date
Application number
AT95919182T
Other languages
English (en)
Inventor
Alexander Schwarz
Meir Department Of Bio Wilchek
Original Assignee
Biosepra Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biosepra Inc filed Critical Biosepra Inc
Application granted granted Critical
Publication of ATE250457T1 publication Critical patent/ATE250457T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204—Inorganic carriers, supports or substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004—Sorbent size or size distribution, e.g. particle size
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/3092—Packing of a container, e.g. packing a cartridge or column
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/3212—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
    • B01J20/3255—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such comprising a cyclic structure containing at least one of the heteroatoms nitrogen, oxygen or sulfur, e.g. heterocyclic or heteroaromatic structures
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/40—Aspects relating to the composition of sorbent or filter aid materials
    • B01J2220/46—Materials comprising a mixture of inorganic and organic materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/58—Use in a single column

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Immunology (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT95919182T 1994-05-16 1995-05-16 Chromatographische adsorbenden, die merkaptoheterozyklische liganden anwenden ATE250457T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/243,861 US5502022A (en) 1994-05-16 1994-05-16 Chromatography adsorbents utilizing mercapto heterocyclic ligands
PCT/US1995/006014 WO1995031279A1 (en) 1994-05-16 1995-05-16 Chromatography adsorbents utilizing mercapto heterocyclic ligands

Publications (1)

Publication Number Publication Date
ATE250457T1 true ATE250457T1 (de) 2003-10-15

Family

ID=22920423

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95919182T ATE250457T1 (de) 1994-05-16 1995-05-16 Chromatographische adsorbenden, die merkaptoheterozyklische liganden anwenden

Country Status (7)

Country Link
US (3) US5502022A (de)
EP (1) EP0764048B1 (de)
JP (1) JP3844496B2 (de)
AT (1) ATE250457T1 (de)
AU (1) AU681035B2 (de)
DE (1) DE69531826T2 (de)
WO (1) WO1995031279A1 (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU672794B2 (en) * 1992-05-07 1996-10-17 Affitech As Immunoglobulin binding proteins derived from L protein and their uses
SE9401960L (sv) * 1994-06-07 1995-12-08 Sven Oscarsson Alkalibeständigt proteinadsorbent
US5652348A (en) * 1994-09-23 1997-07-29 Massey University Chromatographic resins and methods for using same
US5789578A (en) * 1996-01-11 1998-08-04 Massey University Methods for the preparation of resins with ligands attached thereto through a linking group comprising sulfide, sulfoxide or sulfone functionality
DE19623131C2 (de) * 1996-06-10 2001-10-31 Gerhard Harry Scholz Konjugat, Verfahren zu dessen Herstellung sowie dessen Verwendung zur Bindung von Substanzen
WO1998008603A1 (en) * 1996-08-30 1998-03-05 Upfront Chromatography A/S Isolation of immunoglobulins
NZ516848A (en) * 1997-06-20 2004-03-26 Ciphergen Biosystems Inc Retentate chromatography apparatus with applications in biology and medicine
DE10011482B4 (de) * 2000-03-09 2004-06-09 Fresenius Hemocare Gmbh Verfahren zum Herstellen eines Adsorbens zum Absenken der Konzentration von Fibrinogen und/oder Fibrin, Adsorbens und Verwendung des Adsorbens zur Herstellung eines Adsorbers
WO2002076503A1 (en) * 2000-06-20 2002-10-03 Mayo Foundation For Medical Education And Research Treatment of central nervous system diseases by antibodies against glatiramer acetate
US20040226052A1 (en) * 2000-10-13 2004-11-11 Meade Harry M. Methods of producing a target molecule in a transgenic animal and purification of the target molecule
GB2377447B (en) 2001-04-18 2003-06-25 Amersham Biosciences Ab Isolation of dna molecules
US6690956B2 (en) * 2001-09-28 2004-02-10 Bellsouth Intellectual Property Corporation System and method for enabling safe hands-free operation of a wireless telephone in a vehicle
US20030082560A1 (en) * 2001-10-29 2003-05-01 Yingjian Wang Method of making interactive protein arrays
ATE475883T1 (de) * 2001-12-04 2010-08-15 Teva Pharma Verfahren zur messung der wirkstärke von glatirameracetat
FR2834227A1 (fr) * 2001-12-27 2003-07-04 Chiralsep Sarl Materiaux supports optiquement actifs, leur procede de preparation et leurs utilisations
EP1508042A4 (de) * 2002-05-02 2008-04-02 Bio Rad Laboratories Biochips mit mit hydrogelen auf polysaccharidbasis beschichteten oberflächen
EP1527345A2 (de) * 2002-07-29 2005-05-04 Axxima Pharmaceuticals AG Verfahren zur abtrennung von atp-bindenden proteinen durch immobilisierte inhibitoren
WO2004024318A1 (en) 2002-09-13 2004-03-25 Pall Corporation Preparation and use of mixed mode solid substrates for chromatography adsorbents and biochip arrays
US7045366B2 (en) 2003-09-12 2006-05-16 Ciphergen Biosystems, Inc. Photocrosslinked hydrogel blend surface coatings
US20050272917A1 (en) * 2004-05-14 2005-12-08 Hematech, Llc Methods for immunoglobulin purification
EP3127916A1 (de) 2004-06-07 2017-02-08 Therapure Biopharma Inc. Isolierung von plasma- oder serumproteinen
WO2006110350A2 (en) * 2005-03-29 2006-10-19 The Board Of Trustees Of The Leland Stanford Junior University Method of fabricating lipid bilayer membranes on solid supports
US20080220968A1 (en) 2005-07-05 2008-09-11 Ge Healthcare Bio-Sciences Ab [1, 2, 4] Triazolo [1, 5-A] Pyrimidine Derivatives as Chromatographic Adsorbent for the Selective Adsorption of Igg
CN1325516C (zh) * 2005-10-20 2007-07-11 上海交通大学 卵黄免疫球蛋白的仿生亲和纯化方法
ITMO20060182A1 (it) * 2006-06-09 2007-12-10 Generon S R L Apparato per la purificazione di molecole organiche e relativo metodo di realizzazione
SG144809A1 (en) * 2007-01-11 2008-08-28 Millipore U K Ltd Benzimidazole compounds and their use as chromatographic ligands
WO2009007993A2 (en) * 2007-04-23 2009-01-15 Arvind Mallinath Lali A process for purification of immunoglobulins using a pseudobioaffinity adsorbent
EP2265129B1 (de) * 2008-04-08 2015-10-28 Bio-Rad Laboratories, Inc. Chromatographiereinigung von antikörpern
SG178173A1 (en) 2009-07-28 2012-03-29 Instraction Gmbh Specific sorbent for binding proteins and peptides, and separation method using the same
KR101847405B1 (ko) 2010-07-30 2018-04-10 이엠디 밀리포어 코포레이션 크로마토그래피 매질 및 방법
MX352199B (es) * 2010-09-03 2017-11-13 Cabot Corp Star Agentes de relleno modificados y compuestos elastomericos que comprenden los mismos.
JP6038774B2 (ja) * 2011-03-24 2016-12-07 株式会社カネカ タンパク性物質結合性低分子化合物
CN102285941B (zh) * 2011-09-01 2013-03-13 信诺美（北京）化工科技有限公司 2-巯基-4,5-二甲基-1,3,4-噻二唑、其锂盐与二倍体及其合成方法
JP2013193039A (ja) * 2012-03-21 2013-09-30 Swing Corp 焼却飛灰に用いる重金属固定化剤及び焼却飛灰の安定化処理方法
WO2015005361A1 (ja) * 2013-07-08 2015-01-15 国立大学法人京都工芸繊維大学 分離剤
CN106794389A (zh) 2014-09-02 2017-05-31 Emd密理博公司 具有纳米原纤化表面特征的高表面积纤维介质
EP3230299A1 (de) 2014-12-08 2017-10-18 EMD Millipore Corporation Mischbettionenaustauschadsorber
JP6911681B2 (ja) * 2017-09-28 2021-07-28 昭和電工マテリアルズ株式会社 吸着材及び標的物質の精製方法
CN108339539A (zh) * 2018-02-09 2018-07-31 安徽师范大学 新型亲和嗜硫硅球色谱材料及其制备方法和应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3785822A (en) * 1971-06-30 1974-01-15 Witt Overman J De Photographic emulsions and developers containing 2-mercapto heterocyclic compounds
US4631270A (en) * 1978-11-20 1986-12-23 Research Corporation Therapeutically useful pseudopeptides, compositions containing the same and methods of preparation and use
US4381239A (en) * 1981-02-10 1983-04-26 Tanabe Seiyaku Co., Ltd. Method for reducing the pyrogen content of or removing pyrogens from substances contaminated therewith
US4406792A (en) * 1981-11-16 1983-09-27 Glad Magnus J Separation agent
SE451802B (sv) * 1984-05-10 1987-11-02 Jerker Porath Produkt for adsorption av metalljoner
SE470261B (sv) * 1984-05-17 1993-12-20 Jerker Porath Adsorbent för separation och immobilisering av proteiner, sätt att framställa ett adsorbent, samt dess användning för biopolymer fraktionering
SE470099B (sv) * 1984-05-17 1993-11-08 Jerker Porath Sulfonaktiverade tioeteradsorbenter för separation av t ex protein
US4810786A (en) * 1985-04-08 1989-03-07 Nitto Chemical Industry Co., Ltd. Stabilization of xanthan gum in aqueous solution
SE500574C2 (sv) * 1986-02-13 1994-07-18 Gel Innovation Handelsbolag Nitrilofor adsorbent för separation och immobilisering av proteiner, sätt att framställa adsorbentet, samt dess användning för fraktionering och immobilisering av biopolymerer
FR2620062B1 (fr) * 1987-09-08 1992-07-24 Aerospatiale Machine a chanfreiner perfectionnee
WO1989011871A1 (en) 1988-06-01 1989-12-14 Cetus Corporation One-step chromatographic purification of immunotoxin conjugates using a thiophilic matrix
US5215889A (en) * 1988-11-18 1993-06-01 The Regents Of The University Of California Catalytic and reactive polypeptides and methods for their preparation and use
SE466534B (sv) * 1988-12-30 1992-03-02 Exploaterings Ab Tbf Adsorptionsmedel foer metalljoner, proteiner och andra oorganiska och organiska substanser
SE465155B (sv) * 1989-12-19 1991-08-05 Exploaterings Ab Tbf Metallkelatbildande hydrofil polymer foer adsorption etc samt ett saett foer framstaellning av polymeren
US5652348A (en) * 1994-09-23 1997-07-29 Massey University Chromatographic resins and methods for using same
US5656707A (en) * 1995-06-16 1997-08-12 Regents Of The University Of Minnesota Highly cross-linked polymeric supports

Also Published As

Publication number Publication date
AU681035B2 (en) 1997-08-14
WO1995031279A1 (en) 1995-11-23
EP0764048A1 (de) 1997-03-26
AU2514395A (en) 1995-12-05
US6610630B2 (en) 2003-08-26
EP0764048B1 (de) 2003-09-24
EP0764048A4 (de) 1998-03-18
DE69531826T2 (de) 2004-07-08
JP3844496B2 (ja) 2006-11-15
DE69531826D1 (de) 2003-10-30
US20010014649A1 (en) 2001-08-16
US5502022A (en) 1996-03-26
JPH10500615A (ja) 1998-01-20
US5719269A (en) 1998-02-17

Similar Documents

Publication Publication Date Title
ATE250457T1 (de) Chromatographische adsorbenden, die merkaptoheterozyklische liganden anwenden
US4510193B1 (de)
ATE150176T1 (de) Chromatographisches material
DE69815428D1 (de) Adsorptionsreaktor mit radialer Strömung
GR3024489T3 (de)
SE9502084L (sv) Regenererbart adsorptionsfilterskikt
DE59814468D1 (de) Verwendung monolithischer sorbentien für präparative chromatographische trennverfahren
DE69111990D1 (de) Schnellgastrennung durch Druckwechsel-Adsorptionsverfahren.
ES2171755T3 (es) Procedimiento de hidrocianacion de diolefinas.
EP0972530A4 (de) Adsorptionsmittel zum elimineren des hepatitis-c-virus,adsorber und adsorptionsverfahren
NO953484D0 (no) Hydrogengjenvinning ved adsorbent
TR199600608A2 (tr) Azotun diger gazlardan adsorpsiyonla ayrilmasi.
BR0005812A (pt) Processo e composição para adsorção seletiva de um componente de uma mistura gasosa, e, processo para adsorção seletiva de oxigênio de uma mistura gasosa
ATE248859T1 (de) Metallion-ligand koordinationskomplexe, antikorper dagegen und tests die solche antikorper verwenden
FR2635685B1 (fr) Matieres de regeneration du periodonte
ATE219531T1 (de) Technische gewebe für airbags
AU7372291A (en) Purifying fluids by adsorption
GR3004359T3 (de)
DE69114538D1 (de) Gasfeder-betriebenes Spannelement für diverse Werkstücke.
CA2190379A1 (en) Chromatography adsorbents utilizing mercapto heterocyclic ligands
EP0972012A4 (de) Immunsuppression
DK156790A (da) Selebaand til sikkerhedsseler
KR960018097U (ko) 자동차의 가변식 가스 스프링
ATE14845T1 (de) Biologischer filter.
ES1015632U (es) Utensilio para la manicura.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties