ATE247962T1 - Wässrige zusammensetzungen mit ciprofloxacin, verfahren zu deren herstellung und deren verwendung - Google Patents
Wässrige zusammensetzungen mit ciprofloxacin, verfahren zu deren herstellung und deren verwendungInfo
- Publication number
- ATE247962T1 ATE247962T1 AT96924896T AT96924896T ATE247962T1 AT E247962 T1 ATE247962 T1 AT E247962T1 AT 96924896 T AT96924896 T AT 96924896T AT 96924896 T AT96924896 T AT 96924896T AT E247962 T1 ATE247962 T1 AT E247962T1
- Authority
- AT
- Austria
- Prior art keywords
- compositions containing
- aqueous compositions
- production
- containing ciprofloxacin
- ciprofloxacine
- Prior art date
Links
- MYSWGUAQZAJSOK-UHFFFAOYSA-N ciprofloxacin Chemical compound C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 MYSWGUAQZAJSOK-UHFFFAOYSA-N 0.000 title abstract 4
- 229960003405 ciprofloxacin Drugs 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000007853 buffer solution Substances 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- CVAGXMIIJWVUAF-UHFFFAOYSA-N hypochlorous acid;hydrate Chemical compound O.ClO CVAGXMIIJWVUAF-UHFFFAOYSA-N 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- 239000002562 thickening agent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES09501578A ES2106680B1 (es) | 1995-08-03 | 1995-08-03 | Composiciones acuosas conteniendo ciprofloxacino y utilizacion y procedimiento correspondientes. |
| PCT/ES1996/000155 WO1997005880A1 (es) | 1995-08-03 | 1996-07-26 | Composiciones acuosas conteniendo ciprofloxacino y utilizacion y procedimiento correspondientes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE247962T1 true ATE247962T1 (de) | 2003-09-15 |
Family
ID=8291281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96924896T ATE247962T1 (de) | 1995-08-03 | 1996-07-26 | Wässrige zusammensetzungen mit ciprofloxacin, verfahren zu deren herstellung und deren verwendung |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5786363A (de) |
| EP (1) | EP0806206B1 (de) |
| JP (1) | JP4081521B2 (de) |
| AT (1) | ATE247962T1 (de) |
| AU (1) | AU701697B2 (de) |
| CA (1) | CA2200760C (de) |
| DE (1) | DE69629664T2 (de) |
| DK (1) | DK0806206T3 (de) |
| ES (2) | ES2106680B1 (de) |
| PT (1) | PT806206E (de) |
| RU (1) | RU2165755C2 (de) |
| WO (1) | WO1997005880A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2160090B1 (es) * | 2000-03-16 | 2002-07-01 | Vita Invest Sa | Composiciones acuosas de ciprofloxacino, contenidas en envases monodosis y su utilizacion. |
| US8318817B2 (en) | 2008-07-21 | 2012-11-27 | Otonomy, Inc. | Controlled release antimicrobial compositions and methods for the treatment of otic disorders |
| MX2011000862A (es) * | 2008-07-21 | 2011-03-15 | Otonomy Inc | Composiciones antimicrobianas de liberacion controlada y metodos para el tratamiento de trastornos oticos. |
| EP2366408B1 (de) * | 2010-03-01 | 2012-07-18 | Laboratorios SALVAT, S.A. | Wässrige klare Lösungen aus Fluocinolon-Acetonid zur Behandlung von Ohrentzündungen |
| WO2018053173A1 (en) | 2016-09-16 | 2018-03-22 | Otonomy, Inc. | Otic gel formulations for treating otitis externa |
| CN112986468B (zh) * | 2019-12-13 | 2024-05-03 | 武汉九州钰民医药科技有限公司 | 检测盐酸环丙沙星片中氯代环丙沙星的分析方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4670444B1 (en) * | 1980-09-03 | 1999-02-09 | Bayer Ag | and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds |
| DE3537761A1 (de) * | 1985-10-24 | 1987-04-30 | Bayer Ag | Infusionsloesungen der 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-chinolin-3-carbonsaeure |
| DE3632222A1 (de) * | 1986-09-23 | 1988-04-07 | Bayer Ag | Topisch anwendbare zubereitungen von gyrase-inhibitoren |
| DE69224071T2 (de) * | 1991-09-17 | 1998-05-07 | Alcon Lab Inc | Chinolan-antibiotika und polystyrolsulfonat enthaltende zusammensetzungen |
| WO1993017664A1 (en) * | 1992-03-02 | 1993-09-16 | Alcon Laboratories, Inc. | Combinations of cellulosic polymers and carboxy vinyl polymers and their use in pharmaceutical compositions |
-
1995
- 1995-08-03 ES ES09501578A patent/ES2106680B1/es not_active Expired - Fee Related
-
1996
- 1996-07-26 AU AU65201/96A patent/AU701697B2/en not_active Ceased
- 1996-07-26 JP JP50814597A patent/JP4081521B2/ja not_active Expired - Fee Related
- 1996-07-26 US US08/809,622 patent/US5786363A/en not_active Expired - Fee Related
- 1996-07-26 DK DK96924896T patent/DK0806206T3/da active
- 1996-07-26 ES ES96924896T patent/ES2205048T3/es not_active Expired - Lifetime
- 1996-07-26 AT AT96924896T patent/ATE247962T1/de active
- 1996-07-26 EP EP96924896A patent/EP0806206B1/de not_active Expired - Lifetime
- 1996-07-26 DE DE69629664T patent/DE69629664T2/de not_active Expired - Lifetime
- 1996-07-26 PT PT96924896T patent/PT806206E/pt unknown
- 1996-07-26 WO PCT/ES1996/000155 patent/WO1997005880A1/es active IP Right Grant
- 1996-07-26 RU RU97107154/14A patent/RU2165755C2/ru not_active IP Right Cessation
- 1996-07-26 CA CA002200760A patent/CA2200760C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP4081521B2 (ja) | 2008-04-30 |
| ES2106680B1 (es) | 1998-07-01 |
| CA2200760C (en) | 2007-09-11 |
| DE69629664D1 (de) | 2003-10-02 |
| DE69629664T2 (de) | 2004-06-24 |
| RU2165755C2 (ru) | 2001-04-27 |
| JPH11500740A (ja) | 1999-01-19 |
| PT806206E (pt) | 2004-01-30 |
| CA2200760A1 (en) | 1997-02-20 |
| WO1997005880A1 (es) | 1997-02-20 |
| AU701697B2 (en) | 1999-02-04 |
| DK0806206T3 (da) | 2003-12-08 |
| AU6520196A (en) | 1997-03-05 |
| EP0806206A1 (de) | 1997-11-12 |
| ES2106680A1 (es) | 1997-11-01 |
| ES2205048T3 (es) | 2004-05-01 |
| EP0806206B1 (de) | 2003-08-27 |
| US5786363A (en) | 1998-07-28 |
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| EEIH | Change in the person of patent owner | ||
| UEP | Publication of translation of european patent specification |
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