ATE246198T1 - Hydrid-anthrazykline aus gentechnisch hergestellten streptomyces galileaus stämmen - Google Patents
Hydrid-anthrazykline aus gentechnisch hergestellten streptomyces galileaus stämmenInfo
- Publication number
- ATE246198T1 ATE246198T1 AT99923618T AT99923618T ATE246198T1 AT E246198 T1 ATE246198 T1 AT E246198T1 AT 99923618 T AT99923618 T AT 99923618T AT 99923618 T AT99923618 T AT 99923618T AT E246198 T1 ATE246198 T1 AT E246198T1
- Authority
- AT
- Austria
- Prior art keywords
- deoxyfucose
- streptomyces
- galileaus
- anthrazyclines
- hydride
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Compounds Of Unknown Constitution (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI981062A FI105554B (fi) | 1998-05-13 | 1998-05-13 | Geenimuunnelluista Streptomyces galilaeus-kannoista saatavat hybridiantrasykliinit |
| PCT/FI1999/000385 WO1999058544A1 (en) | 1998-05-13 | 1999-05-10 | Hybrid anthracyclines from genetically engineered streptomyces galilaeus strains |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE246198T1 true ATE246198T1 (de) | 2003-08-15 |
Family
ID=8551716
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99923618T ATE246198T1 (de) | 1998-05-13 | 1999-05-10 | Hydrid-anthrazykline aus gentechnisch hergestellten streptomyces galileaus stämmen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6399583B1 (de) |
| EP (1) | EP1000078B1 (de) |
| JP (1) | JP2002514399A (de) |
| AT (1) | ATE246198T1 (de) |
| DE (1) | DE69909938T2 (de) |
| DK (1) | DK1000078T3 (de) |
| ES (1) | ES2205825T3 (de) |
| FI (1) | FI105554B (de) |
| WO (1) | WO1999058544A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2350597A1 (en) * | 1998-12-02 | 2000-06-08 | Barbara Ann Foster | Methods and compositions for restoring conformational stability of a protein of the p53 family |
| US7799904B2 (en) * | 2003-06-13 | 2010-09-21 | University Of Kentucky Research Foundation | Gilvocarcin gene cluster, recombinant production and use thereof |
| US20070270504A1 (en) * | 2003-06-20 | 2007-11-22 | Avalon Pharmaceuticals, Inc. | Identification of Therapeutic Agents Using Genetic Fingerprinting |
| JP2007284351A (ja) * | 2004-07-27 | 2007-11-01 | Osaka Bioscience Institute | アミロイド蛋白質の凝集を抑制する物質とその作用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI93860C (fi) | 1991-03-25 | 1995-06-12 | Leiras Oy | Menetelmä antibioottien tuottamiseksi, siinä käyttökelpoisia DNA-jaksoja, yhdistelmä-DNA-konstruktioita ja näitä sisältäviä mikrobikantoja |
| KR0145943B1 (ko) | 1995-02-03 | 1998-08-01 | 김은영 | 아클라비논 c-11 히드록실라제, 그 유전자, 발현벡터 및 이를 이용한 하이브리드 항생제의 제조방법 |
-
1998
- 1998-05-13 FI FI981062A patent/FI105554B/fi not_active IP Right Cessation
-
1999
- 1999-05-10 DK DK99923618T patent/DK1000078T3/da active
- 1999-05-10 AT AT99923618T patent/ATE246198T1/de not_active IP Right Cessation
- 1999-05-10 US US09/462,671 patent/US6399583B1/en not_active Expired - Fee Related
- 1999-05-10 ES ES99923618T patent/ES2205825T3/es not_active Expired - Lifetime
- 1999-05-10 JP JP2000548348A patent/JP2002514399A/ja not_active Withdrawn
- 1999-05-10 DE DE69909938T patent/DE69909938T2/de not_active Expired - Fee Related
- 1999-05-10 EP EP99923618A patent/EP1000078B1/de not_active Expired - Lifetime
- 1999-05-10 WO PCT/FI1999/000385 patent/WO1999058544A1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| FI105554B (fi) | 2000-09-15 |
| JP2002514399A (ja) | 2002-05-21 |
| FI981062A0 (fi) | 1998-05-13 |
| DE69909938T2 (de) | 2004-05-13 |
| DK1000078T3 (da) | 2003-11-17 |
| ES2205825T3 (es) | 2004-05-01 |
| WO1999058544A9 (en) | 2000-01-20 |
| DE69909938D1 (de) | 2003-09-04 |
| EP1000078A1 (de) | 2000-05-17 |
| FI981062A (fi) | 1999-11-14 |
| US6399583B1 (en) | 2002-06-04 |
| WO1999058544A1 (en) | 1999-11-18 |
| EP1000078B1 (de) | 2003-07-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1000078 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |