ATE244307T1 - Rekombinante proteine des filamentoesen haemaglutinins von bordetella,im besonderen bordetella pertusis, herstellungsverfahren und ihre verwendung zur herstellung von fremdproteinen oder vakzinen - Google Patents

Rekombinante proteine des filamentoesen haemaglutinins von bordetella,im besonderen bordetella pertusis, herstellungsverfahren und ihre verwendung zur herstellung von fremdproteinen oder vakzinen

Info

Publication number
ATE244307T1
ATE244307T1 AT95918030T AT95918030T ATE244307T1 AT E244307 T1 ATE244307 T1 AT E244307T1 AT 95918030 T AT95918030 T AT 95918030T AT 95918030 T AT95918030 T AT 95918030T AT E244307 T1 ATE244307 T1 AT E244307T1
Authority
AT
Austria
Prior art keywords
bordetella
fha
sequence
proteins
pertussis
Prior art date
Application number
AT95918030T
Other languages
English (en)
Inventor
Camille Locht
Genevieve Renauld
Andre Capron
Gilles Riveau
Franco Menozzi
Francoise Jacob-Dubuisson
Original Assignee
Pasteur Institut
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Institut, Inst Nat Sante Rech Med filed Critical Pasteur Institut
Application granted granted Critical
Publication of ATE244307T1 publication Critical patent/ATE244307T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AT95918030T 1994-04-19 1995-04-19 Rekombinante proteine des filamentoesen haemaglutinins von bordetella,im besonderen bordetella pertusis, herstellungsverfahren und ihre verwendung zur herstellung von fremdproteinen oder vakzinen ATE244307T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9404661A FR2718750B1 (fr) 1994-04-19 1994-04-19 Protéines recombinantes de l'hémagglutinine filamenteuse de Bordetella, notamment, B. Pertussis, production et application à la production de protéines étrangères ou de principes actifs vaccinants.
PCT/FR1995/000512 WO1995028486A2 (fr) 1994-04-19 1995-04-19 Proteines recombinantes de l'hemagglutinine filamenteuse de bordetella, notamment bordetella pertussis, procede pour leur production et leurs applications a la production de proteines etrangeres ou de principes actifs vaccinants

Publications (1)

Publication Number Publication Date
ATE244307T1 true ATE244307T1 (de) 2003-07-15

Family

ID=9462257

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95918030T ATE244307T1 (de) 1994-04-19 1995-04-19 Rekombinante proteine des filamentoesen haemaglutinins von bordetella,im besonderen bordetella pertusis, herstellungsverfahren und ihre verwendung zur herstellung von fremdproteinen oder vakzinen

Country Status (11)

Country Link
US (1) US6841358B1 (de)
EP (1) EP0755447B1 (de)
AT (1) ATE244307T1 (de)
AU (1) AU2412195A (de)
CA (1) CA2202639C (de)
DE (1) DE69531200T2 (de)
DK (1) DK0755447T3 (de)
ES (1) ES2202363T3 (de)
FR (1) FR2718750B1 (de)
PT (1) PT755447E (de)
WO (1) WO1995028486A2 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5932714A (en) * 1995-02-23 1999-08-03 Connaught Laboratories Limited Expression of gene products from genetically manipulated strains of Bordetella
FR2754543B1 (fr) * 1996-10-11 1998-12-31 Pasteur Institut Souche de bordetella deficiente dans la production de toxine et exprimant une proteine hydride, liposomes comprenant de la fha et leurs utilisations comme vaccins, et utilisation de la fha pour stimuler les reponses immunitaires
US7087236B1 (en) * 1998-09-01 2006-08-08 Merrion Research I Limited Method for inducing a cell-mediated immune response and improved parenteral vaccine formulations thereof
FR2793492A1 (fr) * 1999-05-11 2000-11-17 Pasteur Institut Nouveau procede de purification par affinite
EP1994139B1 (de) 2006-03-10 2016-07-13 Institut Pasteur De Lille Lebende abgeschwächte bordetella-stämme als einzeldosisimpfstoff gegen keuchhusten
US9526778B2 (en) 2009-06-15 2016-12-27 Institut Pasteur De Lille Influenza vaccine, composition, and methods of use
AU2012331646B2 (en) 2011-11-02 2017-03-30 Institut National De La Sante Et De La Recherche Medicale (Inserm) Effect of an attenuated Bordetella strain against allergic disease
EP2722338A1 (de) 2012-10-17 2014-04-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Neue rekombinante Bordetella-Stämme
US10968446B2 (en) 2012-11-01 2021-04-06 Massachusetts Institute Of Technology Directed evolution of synthetic gene cluster
US9655959B2 (en) 2014-10-01 2017-05-23 National University Of Singapore Adenylate cyclase deficient bordetella strains
RU2769873C2 (ru) 2015-07-13 2022-04-07 Пивот Байо, Инк. Способы и композиции для улучшения признаков растений
BR112018006800A2 (pt) 2015-10-05 2018-10-23 Massachusetts Inst Technology fixação de nitrogênio usando agrupamento (cluster)s nif reestruturados
EP3436034A1 (de) 2016-03-29 2019-02-06 Institut Pasteur de Lille Mutierte bordetella-stämme und verfahren zur verwendung
JP7234116B2 (ja) 2017-01-12 2023-03-07 ピボット バイオ， インコーポレイテッド 植物形質を改善するための方法および組成物
WO2019032926A1 (en) * 2017-08-09 2019-02-14 Pivot Bio, Inc. METHODS AND COMPOSITIONS FOR ENHANCING MODIFIED MICROBES
AU2018353409A1 (en) 2017-10-18 2020-04-16 Institut National De La Santé Et De La Recherche Médicale (Inserm) Bordetella strains expressing serotype 3 Fimbriae
CA3080172A1 (en) 2017-10-25 2019-05-02 Pivot Bio, Inc. Gene targets for nitrogen fixation targeting for improving plant traits
BR112020008035A2 (pt) 2017-10-25 2020-10-27 Pivot Bio, Inc. métodos e composições para aprimorar micróbios geneticamente modificados que fixam nitrogênio
AU2019291824A1 (en) 2018-06-27 2021-01-14 Pivot Bio, Inc. Agricultural compositions comprising remodeled nitrogen fixing microbes

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341123C (en) * 1988-10-27 2000-10-17 David A. Relman Filamentous hemagglutinin of b. pertussis
US6036960A (en) * 1988-10-27 2000-03-14 Relman; David A. Filamentous hemagglutinin of B. pertussis
GB9008746D0 (en) * 1990-04-18 1990-06-13 Connaught Lab The use of autologous promoters to express gene products in bordetella
DE4111531A1 (de) * 1991-04-09 1992-10-29 Biotechnolog Forschung Gmbh Plasmide zur fha-expression und wirte

Also Published As

Publication number Publication date
EP0755447A1 (de) 1997-01-29
DE69531200T2 (de) 2004-04-15
US6841358B1 (en) 2005-01-11
FR2718750B1 (fr) 1996-06-14
CA2202639C (fr) 2004-08-10
AU2412195A (en) 1995-11-10
EP0755447B1 (de) 2003-07-02
CA2202639A1 (fr) 1995-10-26
DK0755447T3 (da) 2003-10-27
ES2202363T3 (es) 2004-04-01
DE69531200D1 (de) 2003-08-07
WO1995028486A3 (fr) 1996-01-11
PT755447E (pt) 2003-12-31
WO1995028486A2 (fr) 1995-10-26
FR2718750A1 (fr) 1995-10-20

Similar Documents

Publication Publication Date Title
ATE244307T1 (de) Rekombinante proteine des filamentoesen haemaglutinins von bordetella,im besonderen bordetella pertusis, herstellungsverfahren und ihre verwendung zur herstellung von fremdproteinen oder vakzinen
ATE80660T1 (de) Verfahren zur herstellung eines polypeptides.
DE69534822D1 (de) Verfahren zur bakteriellen herstellung von heterologen polypeptiden mit disulfidbrücke
FI965220A (fi) Ei-toksinen, ei-toksigeeninen, ei-patogeeninen Fusarium-ilmentämissysteemi ja siinä käytettävät promootterit ja terminaattorit
ATE121781T1 (de) Verwendung von dns-fragmenten, die ein signalpeptid kodieren zur sekretion von reifen proteinen in rekombinanten hefen, expressions- kassetten, transformierte hefen und verfahren zur herstellung dieser proteine.
ATE207124T1 (de) Für das yap3 signalpeptid kodierendes dna- konstrukt
SE8107812L (sv) Rekombinerade dna-molekyler och forfaranden for framstellning av proteiner
KR920012442A (ko) 피치아 파스토리스 산성 인산효소 유전자의 dna 단편 및 이를 사용하는 방법
DE69119454D1 (de) DNA-Fragment, das ein Polypeptid mit Nitrilhydrataseaktivität kodiert, DNA-Fragment enthaltende Transformante und Verfahren zur Herstellung von Amiden unter Verwendung der Transformante
FI863891A (fi) Menetelmiä sekropiinin ja muiden heterologisten polypeptidien tuottamiseksi bakteeri-isännässä araB-promoottoria käyttäen sekä menetelmissä käyttökelpoisia replikoituvia ekspressiovälineitä, geneettisiä muodostelmia ja bakteereja
DE69532646D1 (de) Verfahren zur herstellung extrazellulärer proteine in bakterien
ATE233321T1 (de) Verbesserungen in der herstellung von proteinen in wirtszellen
EP0952158A4 (de) Modifizierte methylotrophe p. pastoris hefe, welche menschliches wachstumshormon sekretiert
KR870007280A (ko) 바실러스에서의 사람 혈청 알부민의 제조방법
DE3850456D1 (de) Klonierung des isoamylaseenzym kodierenden Gens und seine Verwendung zur Herstellung dieses Enzyms.
GR3024625T3 (es) Calcium-regulated promoter
KINBARA et al. A Skeletal Muscle-Specific Calpain, p94, Exists in Myofibrils Bound to
DE58909205D1 (de) Expressionsvektor und Verfahren zur regulierbaren Herstellung von Proteinen in Eukaryonten.
ATE120236T1 (de) T-pa-mutante gk1l.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0755447

Country of ref document: EP