ATE241978T1 - Therapeutische anwendung von dioxabicyclo(3.3.0)oktan-verbindungen - Google Patents
Therapeutische anwendung von dioxabicyclo(3.3.0)oktan-verbindungenInfo
- Publication number
- ATE241978T1 ATE241978T1 AT97112930T AT97112930T ATE241978T1 AT E241978 T1 ATE241978 T1 AT E241978T1 AT 97112930 T AT97112930 T AT 97112930T AT 97112930 T AT97112930 T AT 97112930T AT E241978 T1 ATE241978 T1 AT E241978T1
- Authority
- AT
- Austria
- Prior art keywords
- sup
- dioxabicyclo
- octane
- methoxy
- methylenedioxyphenyl
- Prior art date
Links
- XNWFXTOHNKPYMK-UHFFFAOYSA-N 3,3a,4,5,6,6a-hexahydrocyclopenta[c]dioxole Chemical class C1OOC2CCCC21 XNWFXTOHNKPYMK-UHFFFAOYSA-N 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- PEYUIKBAABKQKQ-AFHBHXEDSA-N (+)-sesamin Chemical compound C1=C2OCOC2=CC([C@H]2OC[C@H]3[C@@H]2CO[C@@H]3C2=CC=C3OCOC3=C2)=C1 PEYUIKBAABKQKQ-AFHBHXEDSA-N 0.000 abstract 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- PEYUIKBAABKQKQ-UHFFFAOYSA-N epiasarinin Natural products C1=C2OCOC2=CC(C2OCC3C2COC3C2=CC=C3OCOC3=C2)=C1 PEYUIKBAABKQKQ-UHFFFAOYSA-N 0.000 abstract 2
- -1 octane compound Chemical class 0.000 abstract 2
- ZZMNWJVJUKMZJY-AFHBHXEDSA-N Sesamolin Chemical compound C1=C2OCOC2=CC([C@H]2OC[C@H]3[C@@H]2CO[C@@H]3OC2=CC=C3OCOC3=C2)=C1 ZZMNWJVJUKMZJY-AFHBHXEDSA-N 0.000 abstract 1
- ZZMNWJVJUKMZJY-UHFFFAOYSA-N Sesamolin Natural products C1=C2OCOC2=CC(C2OCC3C2COC3OC2=CC=C3OCOC3=C2)=C1 ZZMNWJVJUKMZJY-UHFFFAOYSA-N 0.000 abstract 1
- VBIRCRCPHNUJAS-UHFFFAOYSA-N Xanthoxylol Chemical compound C1=C(O)C(OC)=CC(C2C3C(C(OC3)C=3C=C4OCOC4=CC=3)CO2)=C1 VBIRCRCPHNUJAS-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000003908 liver function Effects 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- HGXBRUKMWQGOIE-UHFFFAOYSA-N pinoresinol Chemical compound C1=C(O)C(OC)=CC(C2C3C(C(OC3)C=3C=C(OC)C(O)=CC=3)CO2)=C1 HGXBRUKMWQGOIE-UHFFFAOYSA-N 0.000 abstract 1
- VRMHCMWQHAXTOR-CMOCDZPBSA-N sesamin Natural products C1=C2OCOC2=CC([C@@H]2OC[C@@]3(C)[C@H](C=4C=C5OCOC5=CC=4)OC[C@]32C)=C1 VRMHCMWQHAXTOR-CMOCDZPBSA-N 0.000 abstract 1
- KQRXQIPRDKVZPW-ISZNXKAUSA-N sesaminol Chemical compound C1=C2OCOC2=CC([C@H]2OC[C@H]3[C@@H]2CO[C@@H]3C2=CC=3OCOC=3C=C2O)=C1 KQRXQIPRDKVZPW-ISZNXKAUSA-N 0.000 abstract 1
- KQRXQIPRDKVZPW-UHFFFAOYSA-N sesaminol Natural products C1=C2OCOC2=CC(C2OCC3C2COC3C2=CC=3OCOC=3C=C2O)=C1 KQRXQIPRDKVZPW-UHFFFAOYSA-N 0.000 abstract 1
- OJVGWDJIYBTWDS-UHFFFAOYSA-N sesamolinol Chemical compound C1=C(O)C(OC)=CC(OC2C3C(C(OC3)C=3C=C4OCOC4=CC=3)CO2)=C1 OJVGWDJIYBTWDS-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
- A23D7/00—Edible oil or fat compositions containing an aqueous phase, e.g. margarines
- A23D7/005—Edible oil or fat compositions containing an aqueous phase, e.g. margarines characterised by ingredients other than fatty acid triglycerides
- A23D7/0056—Spread compositions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/60—Salad dressings; Mayonnaise; Ketchup
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Epidemiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Finger-Pressure Massage (AREA)
- Cosmetics (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1187497A JP3001589B2 (ja) | 1989-07-21 | 1989-07-21 | リグナン類含有飲食物 |
| JP8750090 | 1990-04-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE241978T1 true ATE241978T1 (de) | 2003-06-15 |
Family
ID=26428763
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97112930T ATE241978T1 (de) | 1989-07-21 | 1990-07-20 | Therapeutische anwendung von dioxabicyclo(3.3.0)oktan-verbindungen |
| AT90307978T ATE208195T1 (de) | 1989-07-21 | 1990-07-20 | Mittel zur verbesserung der leberfunktion |
| AT97112931T ATE285765T1 (de) | 1989-07-21 | 1990-07-20 | Kapsel, enthaltend ein dioxabicyclo(3.3.0)oktan |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90307978T ATE208195T1 (de) | 1989-07-21 | 1990-07-20 | Mittel zur verbesserung der leberfunktion |
| AT97112931T ATE285765T1 (de) | 1989-07-21 | 1990-07-20 | Kapsel, enthaltend ein dioxabicyclo(3.3.0)oktan |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5180588A (de) |
| EP (3) | EP0818196B1 (de) |
| AT (3) | ATE241978T1 (de) |
| CA (2) | CA2172855C (de) |
| DE (3) | DE69034084T2 (de) |
| DK (3) | DK0409654T3 (de) |
| ES (3) | ES2235205T3 (de) |
| SG (1) | SG42967A1 (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3183664B2 (ja) * | 1990-10-22 | 2001-07-09 | サントリー株式会社 | コレステロール及び胆汁酸の代謝阻害剤 |
| JP3283274B2 (ja) * | 1991-06-15 | 2002-05-20 | サントリー株式会社 | 新規組成物 |
| US20020031563A1 (en) * | 1992-09-30 | 2002-03-14 | Hodge Thomas W. | Method of inhibiting tumor necrosis factor |
| US5397778A (en) * | 1994-02-25 | 1995-03-14 | New England Deaconess Hospital Corporation | Enteral formulations for treatment of inflammation and infection |
| AU1928295A (en) * | 1994-02-25 | 1995-09-11 | New England Deaconess Hospital Corporation | Anti-inflammatory and infection protective effects of sesamin-based lignans |
| JP3818680B2 (ja) * | 1994-05-12 | 2006-09-06 | サントリー株式会社 | アレルギー症状の予防又は改善剤 |
| JPH08268887A (ja) * | 1995-02-01 | 1996-10-15 | Suntory Ltd | 高血圧症又はそれに起因する医学的症状の予防又は改善剤 |
| CN1073825C (zh) * | 1995-07-04 | 2001-10-31 | 三得利公司 | 二氧杂二环[3.3.0]辛烷衍生物的新用途 |
| FR2738828B1 (fr) * | 1995-09-20 | 1997-10-17 | Commissariat Energie Atomique | Utilisation de cyclodextrines naturelles et de leurs derives pour la solubilisation d'agents anti-agregants plaquettaires de la famille des ginkgolides |
| AU7068896A (en) * | 1995-11-09 | 1997-05-15 | Corunum Corporation | Protein composition derived from sesame seed and use thereof |
| US5811313A (en) * | 1997-06-17 | 1998-09-22 | King Pharmaceuticals, Inc. | Identification test for highly refined sesame oil |
| CA2461661A1 (en) * | 2001-10-19 | 2003-05-01 | Maxim Pharmaceuticals, Inc. | Use of histamine to treat liver disease |
| JP4388248B2 (ja) * | 2001-10-29 | 2009-12-24 | 株式会社日立製作所 | 最適ポートフォリオ決定方法および装置 |
| FI114917B (fi) * | 2002-08-29 | 2005-01-31 | Hormos Nutraceutical Oy Ltd | Lignaanikomplekseja |
| TW200633696A (en) * | 2004-12-28 | 2006-10-01 | Suntory Ltd | Sesamin/episesamin compositions |
| CN101404995B (zh) * | 2005-03-31 | 2013-07-31 | 三得利控股株式会社 | 含木脂素类化合物水包油滴型乳剂及含有其的组合物 |
| CN1939921B (zh) | 2005-09-30 | 2012-08-29 | 三得利控股株式会社 | 高含量表芝麻素的组合物的制造方法 |
| JP5069416B2 (ja) * | 2006-03-15 | 2012-11-07 | サントリーホールディングス株式会社 | 吸湿性の改善された飲食品用組成物 |
| KR101451438B1 (ko) | 2006-03-15 | 2014-10-15 | 산토리 홀딩스 가부시키가이샤 | 리보플라빈과 세사민류를 함유하는 조성물 |
| CN101404996B (zh) | 2006-03-31 | 2011-05-18 | 三得利控股株式会社 | 含有木脂素类化合物的组合物 |
| CA2680751C (en) * | 2007-03-15 | 2016-01-26 | Suntory Holdings Limited | Use of dioxabicyclo[3.3.0]octane derivatives as anti-fatigue agents |
| EP2189160A4 (de) * | 2007-09-19 | 2010-10-13 | Suntory Holdings Ltd | Zusammensetzung mit einer sesamin-komponente und einer vitamin-b1-komponente |
| KR101528380B1 (ko) * | 2007-09-19 | 2015-06-11 | 산토리 홀딩스 가부시키가이샤 | 세사민류와 아라키돈산류를 함유하는 조성물 |
| JP6156795B2 (ja) * | 2013-07-05 | 2017-07-05 | 公立大学法人大阪市立大学 | 脂肪細胞分化の抑制用、脂肪細胞の脂肪蓄積量低減用および/または脂肪細胞のアディポネクチン分泌促進用組成物 |
| CN104804012B (zh) * | 2015-04-24 | 2017-06-30 | 沈阳药科大学 | 一种具有抗耐药菌活性的化合物止泻木脂素a及其用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4427694A (en) * | 1982-06-11 | 1984-01-24 | The Vinoxen Company, Inc. | Sesamin as a psychotropic agent |
| DE3788043T2 (de) * | 1986-06-13 | 1994-03-03 | Tsumura & Co | Biphenylabkömmlinge, verfahren zur herstellung und verwendung. |
| JPH01135892A (ja) * | 1987-11-20 | 1989-05-29 | Kuki Sangyo Kk | 抗酸化性物質の製造方法 |
| US4868207A (en) * | 1988-07-28 | 1989-09-19 | Taisho Pharmaceutical Co., Ltd. | Bis (methylenedioxy) biphenyl compounds useful for the treatment of liver diseases |
| JP3070611B2 (ja) * | 1989-03-07 | 2000-07-31 | サントリー株式会社 | △▲上5▼―不飽和化酵素阻害剤 |
| JPH02255616A (ja) * | 1989-03-27 | 1990-10-16 | Rooman Kogyo:Kk | 肝臓疾患用剤 |
-
1990
- 1990-07-20 DE DE69034084T patent/DE69034084T2/de not_active Expired - Lifetime
- 1990-07-20 SG SG1996001570A patent/SG42967A1/en unknown
- 1990-07-20 CA CA002172855A patent/CA2172855C/en not_active Expired - Lifetime
- 1990-07-20 EP EP97112931A patent/EP0818196B1/de not_active Expired - Lifetime
- 1990-07-20 EP EP97112930A patent/EP0826369B1/de not_active Expired - Lifetime
- 1990-07-20 ES ES97112931T patent/ES2235205T3/es not_active Expired - Lifetime
- 1990-07-20 CA CA002021714A patent/CA2021714C/en not_active Expired - Lifetime
- 1990-07-20 AT AT97112930T patent/ATE241978T1/de not_active IP Right Cessation
- 1990-07-20 EP EP90307978A patent/EP0409654B1/de not_active Expired - Lifetime
- 1990-07-20 AT AT90307978T patent/ATE208195T1/de not_active IP Right Cessation
- 1990-07-20 DK DK90307978T patent/DK0409654T3/da active
- 1990-07-20 ES ES90307978T patent/ES2161680T3/es not_active Expired - Lifetime
- 1990-07-20 DE DE69033848T patent/DE69033848T2/de not_active Expired - Lifetime
- 1990-07-20 DK DK97112930T patent/DK0826369T3/da active
- 1990-07-20 US US07/555,586 patent/US5180588A/en not_active Expired - Lifetime
- 1990-07-20 AT AT97112931T patent/ATE285765T1/de not_active IP Right Cessation
- 1990-07-20 DK DK97112931T patent/DK0818196T3/da active
- 1990-07-20 ES ES97112930T patent/ES2195058T3/es not_active Expired - Lifetime
- 1990-07-20 DE DE69034181T patent/DE69034181T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69034084T2 (de) | 2003-12-04 |
| DK0818196T3 (da) | 2005-05-02 |
| SG42967A1 (en) | 1997-10-17 |
| ES2235205T3 (es) | 2005-07-01 |
| DK0409654T3 (da) | 2001-12-27 |
| US5180588A (en) | 1993-01-19 |
| DE69033848D1 (de) | 2001-12-13 |
| DE69034181D1 (de) | 2005-02-03 |
| DE69034084D1 (de) | 2003-07-10 |
| ES2195058T3 (es) | 2003-12-01 |
| CA2172855A1 (en) | 1991-01-22 |
| DE69034181T2 (de) | 2006-01-26 |
| ES2161680T3 (es) | 2001-12-16 |
| EP0409654B1 (de) | 2001-11-07 |
| EP0826369A1 (de) | 1998-03-04 |
| DK0826369T3 (da) | 2003-09-29 |
| EP0818196B1 (de) | 2004-12-29 |
| DE69033848T2 (de) | 2002-04-04 |
| EP0409654A3 (en) | 1992-05-27 |
| CA2172855C (en) | 2000-02-15 |
| EP0409654A2 (de) | 1991-01-23 |
| CA2021714A1 (en) | 1991-01-22 |
| ATE208195T1 (de) | 2001-11-15 |
| CA2021714C (en) | 1996-07-23 |
| ATE285765T1 (de) | 2005-01-15 |
| EP0826369B1 (de) | 2003-06-04 |
| EP0818196A1 (de) | 1998-01-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0826369 Country of ref document: EP |
|
| EELA | Cancelled due to lapse of time |