ATE237583T1 - Verfahren zur herstellung von depsipeptiden und zwischenprodukten davon - Google Patents

Verfahren zur herstellung von depsipeptiden und zwischenprodukten davon

Info

Publication number
ATE237583T1
ATE237583T1 AT97941241T AT97941241T ATE237583T1 AT E237583 T1 ATE237583 T1 AT E237583T1 AT 97941241 T AT97941241 T AT 97941241T AT 97941241 T AT97941241 T AT 97941241T AT E237583 T1 ATE237583 T1 AT E237583T1
Authority
AT
Austria
Prior art keywords
producing
depsipeptids
intermediate products
represent
lower alkyl
Prior art date
Application number
AT97941241T
Other languages
English (en)
Inventor
Ryo Yamanishi
Masaru Ohgaki
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Application granted granted Critical
Publication of ATE237583T1 publication Critical patent/ATE237583T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D273/00Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/12Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT97941241T 1996-10-07 1997-09-24 Verfahren zur herstellung von depsipeptiden und zwischenprodukten davon ATE237583T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP28604796 1996-10-07
PCT/JP1997/003417 WO1998015523A1 (fr) 1996-10-07 1997-09-24 Procede de production de derives de depsideptides et leurs nouveaux intermediaires

Publications (1)

Publication Number Publication Date
ATE237583T1 true ATE237583T1 (de) 2003-05-15

Family

ID=17699289

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97941241T ATE237583T1 (de) 1996-10-07 1997-09-24 Verfahren zur herstellung von depsipeptiden und zwischenprodukten davon

Country Status (12)

Country Link
US (1) US6235875B1 (de)
EP (1) EP0953563B1 (de)
JP (1) JP4035852B2 (de)
CN (1) CN1205177C (de)
AT (1) ATE237583T1 (de)
BR (1) BR9712279A (de)
CA (1) CA2267376C (de)
DE (1) DE69721055T2 (de)
DK (1) DK0953563T3 (de)
ES (1) ES2191852T3 (de)
PT (1) PT953563E (de)
WO (1) WO1998015523A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU755709B2 (en) * 1997-11-10 2002-12-19 Astellas Pharma Inc. Novel crystal of depsipeptide derivative and process for producing the same
AU2005307814A1 (en) * 2004-11-17 2006-05-26 The University Of Chicago Histone deacetylase inhibitors and methods of use
BR112017024773A2 (pt) 2015-05-20 2018-11-06 Merial, Inc. compostos depsipeptídeos anti-helmínticos
CA3009867C (en) 2015-12-28 2022-05-31 Merial, Inc. Anthelmintic cyclic depsipeptide compounds
WO2018093920A1 (en) 2016-11-16 2018-05-24 Merial, Inc. Anthelmintic depsipeptide compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2874342B2 (ja) 1992-03-17 1999-03-24 藤沢薬品工業株式会社 デプシペプチド誘導体,その製法およびその用途
DE4317432A1 (de) * 1993-05-26 1994-12-01 Bayer Ag Octacyclodepsipeptide mit endoparasitizider Wirkung
DE4317457A1 (de) * 1993-05-26 1994-12-01 Bayer Ag Octacyclodepsipeptide mit endoparasitizider Wirkung
WO1995007272A1 (en) 1993-09-06 1995-03-16 Fujisawa Pharmaceutical Co., Ltd. Cyclodepsipeptide compound
ATE425973T1 (de) 1995-06-30 2009-04-15 Astellas Pharma Inc Depsipeptid-derivat, verfahren zu dessen herstellung und zwischenprodukt dafur

Also Published As

Publication number Publication date
CN1232446A (zh) 1999-10-20
CN1205177C (zh) 2005-06-08
BR9712279A (pt) 1999-08-31
US6235875B1 (en) 2001-05-22
PT953563E (pt) 2003-08-29
WO1998015523A1 (fr) 1998-04-16
CA2267376A1 (en) 1998-04-16
CA2267376C (en) 2006-11-14
EP0953563A1 (de) 1999-11-03
DK0953563T3 (da) 2003-07-28
ES2191852T3 (es) 2003-09-16
EP0953563B1 (de) 2003-04-16
DE69721055D1 (de) 2003-05-22
EP0953563A4 (de) 2001-05-16
JP4035852B2 (ja) 2008-01-23
DE69721055T2 (de) 2004-02-19

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