ATE229979T1 - Transferrinrezeptor protein aus moraxella - Google Patents
Transferrinrezeptor protein aus moraxellaInfo
- Publication number
- ATE229979T1 ATE229979T1 AT96933285T AT96933285T ATE229979T1 AT E229979 T1 ATE229979 T1 AT E229979T1 AT 96933285 T AT96933285 T AT 96933285T AT 96933285 T AT96933285 T AT 96933285T AT E229979 T1 ATE229979 T1 AT E229979T1
- Authority
- AT
- Austria
- Prior art keywords
- receptor protein
- transferrin receptor
- moraxella
- strain
- isolated
- Prior art date
Links
- 102000007238 Transferrin Receptors Human genes 0.000 title abstract 5
- 108010033576 Transferrin Receptors Proteins 0.000 title abstract 5
- 241000588621 Moraxella Species 0.000 title abstract 3
- 241000588655 Moraxella catarrhalis Species 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
- C07K14/212—Moraxellaceae, e.g. Acinetobacter, Moraxella, Oligella, Psychrobacter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/5555—Muramyl dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55588—Adjuvants of undefined constitution
- A61K2039/55594—Adjuvants of undefined constitution from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/540,753 US6290970B1 (en) | 1995-10-11 | 1995-10-11 | Transferrin receptor protein of Moraxella |
| PCT/CA1996/000684 WO1997013785A1 (en) | 1995-10-11 | 1996-10-11 | Transferrin receptor protein of moraxella |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE229979T1 true ATE229979T1 (de) | 2003-01-15 |
Family
ID=24156797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96933285T ATE229979T1 (de) | 1995-10-11 | 1996-10-11 | Transferrinrezeptor protein aus moraxella |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6290970B1 (de) |
| EP (1) | EP0866803B1 (de) |
| JP (2) | JP4005634B2 (de) |
| CN (1) | CN1318446C (de) |
| AT (1) | ATE229979T1 (de) |
| AU (1) | AU711791B2 (de) |
| BR (2) | BR9610872A (de) |
| CA (1) | CA2234409C (de) |
| DE (1) | DE69625513T2 (de) |
| WO (1) | WO1997013785A1 (de) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6290970B1 (en) * | 1995-10-11 | 2001-09-18 | Aventis Pasteur Limited | Transferrin receptor protein of Moraxella |
| US6090576A (en) * | 1996-03-08 | 2000-07-18 | Connaught Laboratories Limited | DNA encoding a transferrin receptor of Moraxella |
| US6440701B1 (en) * | 1996-03-08 | 2002-08-27 | Aventis Pasteur Limited | Transferrin receptor genes of Moraxella |
| PT1005487E (pt) * | 1997-01-31 | 2006-12-29 | Wyeth Corp | A proteína de membrana externa de 74 kilodalton de moraxella catarrhalis |
| GB9810285D0 (en) * | 1998-05-13 | 1998-07-15 | Smithkline Beecham Biolog | Novel compounds |
| EP1880735A3 (de) | 1999-03-19 | 2008-03-12 | GlaxoSmithKline Biologicals S.A. | Impfstoff |
| US7241449B1 (en) | 1999-04-12 | 2007-07-10 | Aventis Pasteur Limited | Transferrin receptor genes of moraxella |
| GB9918038D0 (en) * | 1999-07-30 | 1999-09-29 | Smithkline Beecham Biolog | Novel compounds |
| GB9918279D0 (en) * | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Novel compounds |
| GB9918302D0 (en) | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Novel compounds |
| GB9918208D0 (en) * | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Novel compounds |
| GB9921692D0 (en) * | 1999-09-14 | 1999-11-17 | Smithkline Beecham Sa | Novel compounds |
| GB0022742D0 (en) | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
| GB0103171D0 (en) | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
| ES2541351T3 (es) | 2002-02-25 | 2015-07-17 | Vaxiion Therapeutics, Llc | Composiciones de minicélulas y procedimientos |
| MY149591A (en) | 2002-08-02 | 2013-09-13 | Glaxosmithkline Biolog Sa | Vaccines comprising l2 and/or l3 los from neisseria |
| TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
| GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
| EP3020411A1 (de) | 2005-12-22 | 2016-05-18 | GlaxoSmithKline Biologicals s.a. | Impfstoff |
| CN101374859B (zh) | 2006-01-17 | 2014-11-26 | 阿恩·福斯格伦 | 新的表面外露流感嗜血菌蛋白质(蛋白质E;pE) |
| MX2009013949A (es) | 2007-06-26 | 2010-05-24 | Glaxosmithkline Biolog Sa | Vacuna que comprende conjugados de polisacárido capsular de streptococcus pneumoniae. |
| GB201003922D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Conjugation process |
| GB201003924D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| EP2544714A1 (de) | 2010-03-10 | 2013-01-16 | GlaxoSmithKline Biologicals S.A. | Impfstoffzusammensetzung |
| SI2646470T1 (sl) | 2010-11-30 | 2017-05-31 | F. Hoffmann-La Roche Ag | Protitelesa proti receptorjem antitransferina in njihova uporaba za prenos terapevtskega enoverižnega variabilnega fragmenta (scfv) prek krvno-možganske pregrade |
| GB201103836D0 (en) | 2011-03-07 | 2011-04-20 | Glaxosmithkline Biolog Sa | Conjugation process |
| GB201518684D0 (en) | 2015-10-21 | 2015-12-02 | Glaxosmithkline Biolog Sa | Vaccine |
| GB201621686D0 (en) | 2016-12-20 | 2017-02-01 | Glaxosmithkline Biologicals Sa | Novel methods for inducing an immune response |
| CN111032080A (zh) | 2017-05-30 | 2020-04-17 | 葛兰素史密丝克莱恩生物有限公司 | 用于制造佐剂的新型方法 |
| EP3717001A1 (de) | 2017-12-01 | 2020-10-07 | GlaxoSmithKline Biologicals S.A. | Saponinreinigung |
| CA3107077A1 (en) | 2018-08-07 | 2020-02-13 | Glaxosmithkline Biologicals Sa | Processes and vaccines |
| US20220339282A1 (en) | 2018-11-29 | 2022-10-27 | Glaxosmithkline Biologicals Sa | Methods for manufacturing an adjuvant |
| EP3980044A1 (de) | 2019-06-05 | 2022-04-13 | GlaxoSmithKline Biologicals SA | Saponinreinigung |
| KR102312897B1 (ko) * | 2021-02-26 | 2021-10-15 | 에스케이바이오사이언스(주) | 목적 단백질의 고수율 정제방법 |
| GB202205833D0 (en) | 2022-04-21 | 2022-06-08 | Glaxosmithkline Biologicals Sa | Bacteriophage |
| EP4558170A1 (de) | 2022-07-19 | 2025-05-28 | GlaxoSmithKline Biologicals S.A. | Kontinuierliches verfahren zur herstellung von impfstoffen |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ230747A (en) | 1988-09-30 | 1992-05-26 | Bror Morein | Immunomodulating matrix comprising a complex of at least one lipid and at least one saponin; certain glycosylated triterpenoid saponins derived from quillaja saponaria molina |
| US5292869A (en) | 1989-04-27 | 1994-03-08 | The Board Of Governors Of The University | Method for isolating and purifying transferrin and lactoferrin receptor proteins from bacteria and the preparation of vaccines containing the same |
| WO1991006287A1 (en) | 1989-11-06 | 1991-05-16 | Enzytech, Inc. | Protein microspheres and methods of using them |
| US5443832A (en) * | 1990-04-16 | 1995-08-22 | Institut Swisse De Recherches Experimentales Sur Le Cancer | Hydroxyapatite-antigen conjugates and methods for generating a poly-Ig immune response |
| US5552146A (en) * | 1991-08-15 | 1996-09-03 | Board Of Regents, The University Of Texas System | Methods and compositions relating to useful antigens of Moraxella catarrhalis |
| FR2682114B1 (fr) * | 1991-10-03 | 1996-02-23 | Pasteur Merieux Serums Vacc | Vaccin de sous-unite contre les infections a neisseria meningitidis et sous-unites correspondantes a l'etat purifie. |
| FR2682041B1 (fr) * | 1991-10-03 | 1994-01-14 | Pasteur Merieux Serums Vaccins | Vaccin contre les infections a neisseria meningitidis. |
| FR2692592B1 (fr) * | 1992-06-19 | 1995-03-31 | Pasteur Merieux Serums Vacc | Fragments d'ADN codant pour les sous-unités du récepteur de la transferrine de Neisseria meningitidis et procédés les exprimant. |
| US6358727B1 (en) * | 1993-11-08 | 2002-03-19 | Aventis Pasteur Limited | Haemophilus transferrin receptor genes |
| US5681570A (en) * | 1995-01-12 | 1997-10-28 | Connaught Laboratories Limited | Immunogenic conjugate molecules |
| US6290970B1 (en) * | 1995-10-11 | 2001-09-18 | Aventis Pasteur Limited | Transferrin receptor protein of Moraxella |
| US6090576A (en) * | 1996-03-08 | 2000-07-18 | Connaught Laboratories Limited | DNA encoding a transferrin receptor of Moraxella |
| US5977337A (en) * | 1997-06-03 | 1999-11-02 | Connaught Laboratories Limited | Lactoferrin receptor genes of Moraxella |
-
1995
- 1995-10-11 US US08/540,753 patent/US6290970B1/en not_active Expired - Lifetime
-
1996
- 1996-10-11 DE DE69625513T patent/DE69625513T2/de not_active Expired - Lifetime
- 1996-10-11 JP JP51459297A patent/JP4005634B2/ja not_active Expired - Fee Related
- 1996-10-11 AU AU72082/96A patent/AU711791B2/en not_active Ceased
- 1996-10-11 CA CA002234409A patent/CA2234409C/en not_active Expired - Fee Related
- 1996-10-11 BR BR9610872-0A patent/BR9610872A/pt not_active IP Right Cessation
- 1996-10-11 US US09/051,320 patent/US6190668B1/en not_active Expired - Lifetime
- 1996-10-11 BR BRPI9610872-0B8D patent/BR9610872B8/pt unknown
- 1996-10-11 AT AT96933285T patent/ATE229979T1/de not_active IP Right Cessation
- 1996-10-11 CN CNB96198905XA patent/CN1318446C/zh not_active Expired - Fee Related
- 1996-10-11 WO PCT/CA1996/000684 patent/WO1997013785A1/en not_active Ceased
- 1996-10-11 EP EP96933285A patent/EP0866803B1/de not_active Expired - Lifetime
-
2007
- 2007-06-26 JP JP2007168168A patent/JP2007291128A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE69625513D1 (de) | 2003-01-30 |
| EP0866803A1 (de) | 1998-09-30 |
| CA2234409C (en) | 2005-05-17 |
| US6190668B1 (en) | 2001-02-20 |
| WO1997013785A1 (en) | 1997-04-17 |
| JP2007291128A (ja) | 2007-11-08 |
| CN1204344A (zh) | 1999-01-06 |
| JP4005634B2 (ja) | 2007-11-07 |
| AU7208296A (en) | 1997-04-30 |
| BR9610872B8 (pt) | 2014-08-05 |
| BR9610872A (pt) | 2005-08-09 |
| CN1318446C (zh) | 2007-05-30 |
| DE69625513T2 (de) | 2003-11-06 |
| EP0866803B1 (de) | 2002-12-18 |
| US6290970B1 (en) | 2001-09-18 |
| JPH11500744A (ja) | 1999-01-19 |
| AU711791B2 (en) | 1999-10-21 |
| CA2234409A1 (en) | 1997-04-17 |
| HK1017695A1 (en) | 1999-11-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |