ATE229501T1 - Substituierte n-arylmethylamino-cyclobuten-3,4- dion-derivate - Google Patents
Substituierte n-arylmethylamino-cyclobuten-3,4- dion-derivateInfo
- Publication number
- ATE229501T1 ATE229501T1 AT97936050T AT97936050T ATE229501T1 AT E229501 T1 ATE229501 T1 AT E229501T1 AT 97936050 T AT97936050 T AT 97936050T AT 97936050 T AT97936050 T AT 97936050T AT E229501 T1 ATE229501 T1 AT E229501T1
- Authority
- AT
- Austria
- Prior art keywords
- arylmethylamino
- cyclobutene
- substituted
- dione derivatives
- angina
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/20—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/41—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/24—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68220796A | 1996-07-17 | 1996-07-17 | |
US68427896A | 1996-07-17 | 1996-07-17 | |
US67843096A | 1996-07-17 | 1996-07-17 | |
US68427996A | 1996-07-17 | 1996-07-17 | |
US08/889,164 US5763474A (en) | 1996-07-17 | 1997-07-07 | Substituted N-arylmethylamino derivatives of cyclobutene-3,4-diones |
US08/889,165 US5846999A (en) | 1996-07-17 | 1997-07-07 | Substituted N-arylmethylamino derivatives of cyclobutene-3,4-diones |
US08/889,163 US5750574A (en) | 1996-07-17 | 1997-07-07 | Fluorinated N-arylmethylamino derivatives of cyclobutene-3,4-diones |
US08/889,166 US5780505A (en) | 1996-07-17 | 1997-07-07 | Substituted N-arylmethylamino derivatives of cyclobutene-3, 4-diones |
PCT/US1997/011992 WO1998002413A1 (en) | 1996-07-17 | 1997-07-16 | Substituted n-arylmethylamino derivatives of cyclobutene-3,4-diones |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE229501T1 true ATE229501T1 (de) | 2002-12-15 |
Family
ID=27575501
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97936050T ATE229501T1 (de) | 1996-07-17 | 1997-07-16 | Substituierte n-arylmethylamino-cyclobuten-3,4- dion-derivate |
Country Status (8)
Country | Link |
---|---|
EP (2) | EP0934257B1 (de) |
JP (1) | JP2000513729A (de) |
KR (1) | KR20000023769A (de) |
CN (1) | CN1230173A (de) |
AT (1) | ATE229501T1 (de) |
CA (1) | CA2261072A1 (de) |
DE (1) | DE69717841T2 (de) |
WO (1) | WO1998002413A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ290178B6 (cs) | 1999-07-22 | 2002-06-12 | Sankyo Company Limited | Deriváty cyklobutenu |
US6495576B2 (en) | 2001-02-07 | 2002-12-17 | Abbott Laboratories | Aminal diones as potassium channel openers |
US20040106794A1 (en) * | 2001-04-16 | 2004-06-03 | Schering Corporation | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
CN106631843A (zh) * | 2016-11-23 | 2017-05-10 | 山东友帮生化科技有限公司 | 一种3‑氧代环丁基氨的制备方法 |
CN116640071A (zh) * | 2023-05-04 | 2023-08-25 | 四川青木制药有限公司 | 一种制备2-甲基4-甲醛肟基苯甲酸及其酯类衍生物的方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI832520L (fi) * | 1982-07-12 | 1984-01-13 | Bristol Myers Co | Farmaceutiska foerfaranden och sammansaettningar |
US5168103A (en) * | 1991-01-22 | 1992-12-01 | American Home Products Corporation | [[2-(amino-3,4-dioxo-1-cyclobuten-1-yl) amino]alkyl]-acid derivatives |
JPH0692915A (ja) * | 1992-07-28 | 1994-04-05 | Sumitomo Metal Ind Ltd | 1,2−ジアミノシクロブテン−3,4−ジオン誘導体及びその用途 |
US5466712A (en) * | 1994-11-04 | 1995-11-14 | American Home Products Corporation | Substituted n-aryl-1,2-diaminocyclobutene-3,4-diones |
-
1997
- 1997-07-16 EP EP97936050A patent/EP0934257B1/de not_active Expired - Lifetime
- 1997-07-16 AT AT97936050T patent/ATE229501T1/de not_active IP Right Cessation
- 1997-07-16 EP EP01119663A patent/EP1151990A1/de not_active Withdrawn
- 1997-07-16 CA CA002261072A patent/CA2261072A1/en not_active Abandoned
- 1997-07-16 CN CN97197755A patent/CN1230173A/zh active Pending
- 1997-07-16 DE DE69717841T patent/DE69717841T2/de not_active Expired - Fee Related
- 1997-07-16 JP JP10506136A patent/JP2000513729A/ja active Pending
- 1997-07-16 WO PCT/US1997/011992 patent/WO1998002413A1/en active IP Right Grant
-
1999
- 1999-01-14 KR KR1019997000239A patent/KR20000023769A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2261072A1 (en) | 1998-01-22 |
EP0934257B1 (de) | 2002-12-11 |
EP0934257A1 (de) | 1999-08-11 |
WO1998002413A1 (en) | 1998-01-22 |
DE69717841T2 (de) | 2003-05-28 |
CN1230173A (zh) | 1999-09-29 |
KR20000023769A (ko) | 2000-04-25 |
EP1151990A1 (de) | 2001-11-07 |
JP2000513729A (ja) | 2000-10-17 |
DE69717841D1 (de) | 2003-01-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |