ATE2273T1 - Verfahren zur chemischen abspaltung des acylrestes von cephalosporinen und penicillinen. - Google Patents
Verfahren zur chemischen abspaltung des acylrestes von cephalosporinen und penicillinen.Info
- Publication number
- ATE2273T1 ATE2273T1 AT80302107T AT80302107T ATE2273T1 AT E2273 T1 ATE2273 T1 AT E2273T1 AT 80302107 T AT80302107 T AT 80302107T AT 80302107 T AT80302107 T AT 80302107T AT E2273 T1 ATE2273 T1 AT E2273T1
- Authority
- AT
- Austria
- Prior art keywords
- penicillins
- cephalosporins
- acyl residue
- chemical removal
- acyl
- Prior art date
Links
- 229930186147 Cephalosporin Natural products 0.000 title abstract 2
- 229930182555 Penicillin Natural products 0.000 title abstract 2
- 229940124587 cephalosporin Drugs 0.000 title abstract 2
- 150000002960 penicillins Chemical class 0.000 title abstract 2
- HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 title 1
- VRVRGVPWCUEOGV-UHFFFAOYSA-N 2-aminothiophenol Chemical compound NC1=CC=CC=C1S VRVRGVPWCUEOGV-UHFFFAOYSA-N 0.000 abstract 1
- 150000003855 acyl compounds Chemical class 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- JSYGRUBHOCKMGQ-UHFFFAOYSA-N dichloramine Chemical compound ClNCl JSYGRUBHOCKMGQ-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/055,250 US4252973A (en) | 1979-07-06 | 1979-07-06 | Process for chemically removing the acyl sidechain from cephalosporins and penicillins |
| EP80302107A EP0022326B1 (de) | 1979-07-06 | 1980-06-23 | Verfahren zur chemischen Abspaltung des Acylrestes von Cephalosporinen und Penicillinen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE2273T1 true ATE2273T1 (de) | 1983-02-15 |
Family
ID=21996667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT80302107T ATE2273T1 (de) | 1979-07-06 | 1980-06-23 | Verfahren zur chemischen abspaltung des acylrestes von cephalosporinen und penicillinen. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4252973A (de) |
| EP (1) | EP0022326B1 (de) |
| JP (1) | JPS5625186A (de) |
| AT (1) | ATE2273T1 (de) |
| CA (1) | CA1146538A (de) |
| DE (1) | DE3061676D1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT378774B (de) * | 1982-08-06 | 1985-09-25 | Biochemie Gmbh | Verfahren zur deacylierung von penicillinen und cephalosporinen |
| US5159071A (en) * | 1990-09-06 | 1992-10-27 | Ranbaxy Laboratories Limited | Process for the manufacture of 7-amino-3-exomethylene-3-cepham-4-carboxylic acid ester |
| US5604222A (en) * | 1993-12-27 | 1997-02-18 | Lupin Laboratories, Ltd. | Method for the preparation of 2-chloro sulfinyl azetidinones |
| US5578721A (en) * | 1994-07-11 | 1996-11-26 | Lupin Laboratories Limited | Process for preparation of 3-exomethylene cepham sulfoxide esters |
| JP4383557B2 (ja) | 1998-07-01 | 2009-12-16 | 大塚化学株式会社 | ３−セフェム化合物の製造方法 |
| JP2002316991A (ja) * | 2001-04-18 | 2002-10-31 | Otsuka Chem Co Ltd | ペニシリン及びセファロスポリン化合物 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3697515A (en) * | 1963-02-18 | 1972-10-10 | Ciba Geigy Corp | Process for splitting the 7-n-acyl group from cephalosporin compounds |
| US3875151A (en) * | 1963-02-18 | 1975-04-01 | Ciba Geigy Corp | Process for the manufacture of amino-compounds |
| US3499909A (en) * | 1966-05-18 | 1970-03-10 | Koninklijke Gist Spiritus | Process for production of 6-aminopenicillanic acid |
| US3549628A (en) * | 1967-07-07 | 1970-12-22 | Lilly Co Eli | Side chain cleavage in desacetoxycephalosporin esters |
| US3575970A (en) * | 1967-08-07 | 1971-04-20 | Koninklijke Gist Spiritus | Process for preparation of 7-amino-cephalosporanic acid compounds |
| US3573296A (en) * | 1968-07-01 | 1971-03-30 | Bristol Myers Co | Process for the preparation of 7-aminocephalosporanic acid |
| US3573295A (en) * | 1968-07-01 | 1971-03-30 | Bristol Myers Co | Process for the preparation of 7-aminocephalosporanic acid |
| US3920638A (en) * | 1968-08-20 | 1975-11-18 | Ciba Geigy Corp | Process for preparation of 7-amino-cephalosporanic acid compound |
| CH594684A5 (de) | 1971-09-13 | 1978-01-31 | Takeda Chemical Industries Ltd | |
| US3840532A (en) * | 1972-05-01 | 1974-10-08 | Lilly Co Eli | Process for cleaving cephalosporin compounds |
| JPS5626674B2 (de) * | 1973-12-27 | 1981-06-19 | ||
| US4068071A (en) * | 1973-12-28 | 1978-01-10 | Takeda Chemical Industries, Ltd. | Process for producing 6-aminopenicillanic acid or 7-aminocephalosporanic acid derivatives |
| US3932392A (en) * | 1974-01-14 | 1976-01-13 | Bristol-Myers Company | Process for the preparation of 7-aminocephalosporanic acids |
| US4031087A (en) * | 1975-06-27 | 1977-06-21 | Shell Oil Company | 3,4,7,8-Tetrahydro-9-nitro-7-substituted-2H,6H-pyrimido-(4,3-b)(1,3)thiazines |
-
1979
- 1979-07-06 US US06/055,250 patent/US4252973A/en not_active Expired - Lifetime
-
1980
- 1980-06-19 CA CA000354388A patent/CA1146538A/en not_active Expired
- 1980-06-23 EP EP80302107A patent/EP0022326B1/de not_active Expired
- 1980-06-23 DE DE8080302107T patent/DE3061676D1/de not_active Expired
- 1980-06-23 AT AT80302107T patent/ATE2273T1/de not_active IP Right Cessation
- 1980-07-05 JP JP9218780A patent/JPS5625186A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0022326B1 (de) | 1983-01-19 |
| CA1146538A (en) | 1983-05-17 |
| US4252973A (en) | 1981-02-24 |
| JPS5625186A (en) | 1981-03-10 |
| EP0022326A1 (de) | 1981-01-14 |
| DE3061676D1 (en) | 1983-02-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |