DE3061676D1 - Process for chemically removing the acyl sidechain from cephalosporins and penicillins - Google Patents

Process for chemically removing the acyl sidechain from cephalosporins and penicillins

Info

Publication number
DE3061676D1
DE3061676D1 DE8080302107T DE3061676T DE3061676D1 DE 3061676 D1 DE3061676 D1 DE 3061676D1 DE 8080302107 T DE8080302107 T DE 8080302107T DE 3061676 T DE3061676 T DE 3061676T DE 3061676 D1 DE3061676 D1 DE 3061676D1
Authority
DE
Germany
Prior art keywords
penicillins
cephalosporins
chemically removing
acyl
sidechain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080302107T
Other languages
English (en)
Inventor
William A Slusarchyk
Christopher M Cimarusti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Application granted granted Critical
Publication of DE3061676D1 publication Critical patent/DE3061676D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DE8080302107T 1979-07-06 1980-06-23 Process for chemically removing the acyl sidechain from cephalosporins and penicillins Expired DE3061676D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/055,250 US4252973A (en) 1979-07-06 1979-07-06 Process for chemically removing the acyl sidechain from cephalosporins and penicillins

Publications (1)

Publication Number Publication Date
DE3061676D1 true DE3061676D1 (en) 1983-02-24

Family

ID=21996667

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080302107T Expired DE3061676D1 (en) 1979-07-06 1980-06-23 Process for chemically removing the acyl sidechain from cephalosporins and penicillins

Country Status (6)

Country Link
US (1) US4252973A (de)
EP (1) EP0022326B1 (de)
JP (1) JPS5625186A (de)
AT (1) ATE2273T1 (de)
CA (1) CA1146538A (de)
DE (1) DE3061676D1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT378774B (de) * 1982-08-06 1985-09-25 Biochemie Gmbh Verfahren zur deacylierung von penicillinen und cephalosporinen
US5159071A (en) * 1990-09-06 1992-10-27 Ranbaxy Laboratories Limited Process for the manufacture of 7-amino-3-exomethylene-3-cepham-4-carboxylic acid ester
US5604222A (en) * 1993-12-27 1997-02-18 Lupin Laboratories, Ltd. Method for the preparation of 2-chloro sulfinyl azetidinones
US5578721A (en) * 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters
JP4383557B2 (ja) * 1998-07-01 2009-12-16 大塚化学株式会社 ３−セフェム化合物の製造方法
JP2002316991A (ja) * 2001-04-18 2002-10-31 Otsuka Chem Co Ltd ペニシリン及びセファロスポリン化合物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3875151A (en) * 1963-02-18 1975-04-01 Ciba Geigy Corp Process for the manufacture of amino-compounds
US3697515A (en) * 1963-02-18 1972-10-10 Ciba Geigy Corp Process for splitting the 7-n-acyl group from cephalosporin compounds
US3499909A (en) * 1966-05-18 1970-03-10 Koninklijke Gist Spiritus Process for production of 6-aminopenicillanic acid
US3549628A (en) * 1967-07-07 1970-12-22 Lilly Co Eli Side chain cleavage in desacetoxycephalosporin esters
US3575970A (en) * 1967-08-07 1971-04-20 Koninklijke Gist Spiritus Process for preparation of 7-amino-cephalosporanic acid compounds
US3573296A (en) * 1968-07-01 1971-03-30 Bristol Myers Co Process for the preparation of 7-aminocephalosporanic acid
US3573295A (en) * 1968-07-01 1971-03-30 Bristol Myers Co Process for the preparation of 7-aminocephalosporanic acid
US3920638A (en) * 1968-08-20 1975-11-18 Ciba Geigy Corp Process for preparation of 7-amino-cephalosporanic acid compound
US3840532A (en) * 1972-05-01 1974-10-08 Lilly Co Eli Process for cleaving cephalosporin compounds
JPS5626674B2 (de) * 1973-12-27 1981-06-19
US4068071A (en) * 1973-12-28 1978-01-10 Takeda Chemical Industries, Ltd. Process for producing 6-aminopenicillanic acid or 7-aminocephalosporanic acid derivatives
US3932392A (en) * 1974-01-14 1976-01-13 Bristol-Myers Company Process for the preparation of 7-aminocephalosporanic acids
US4031087A (en) * 1975-06-27 1977-06-21 Shell Oil Company 3,4,7,8-Tetrahydro-9-nitro-7-substituted-2H,6H-pyrimido-(4,3-b)(1,3)thiazines

Also Published As

Publication number Publication date
JPS5625186A (en) 1981-03-10
EP0022326A1 (de) 1981-01-14
US4252973A (en) 1981-02-24
EP0022326B1 (de) 1983-01-19
CA1146538A (en) 1983-05-17
ATE2273T1 (de) 1983-02-15

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee