ATE227277T1 - Isoxazoline derivate und ihre verwendung als antimikroben - Google Patents

Isoxazoline derivate und ihre verwendung als antimikroben

Info

Publication number
ATE227277T1
ATE227277T1 AT97937156T AT97937156T ATE227277T1 AT E227277 T1 ATE227277 T1 AT E227277T1 AT 97937156 T AT97937156 T AT 97937156T AT 97937156 T AT97937156 T AT 97937156T AT E227277 T1 ATE227277 T1 AT E227277T1
Authority
AT
Austria
Prior art keywords
antimicrobes
isoxazoline derivatives
isoxazoline
derivatives
formula
Prior art date
Application number
AT97937156T
Other languages
German (de)
English (en)
Inventor
Michael R Barbachyn
Richard C Thomas
Gary J Cleek
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of ATE227277T1 publication Critical patent/ATE227277T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT97937156T 1996-08-21 1997-08-15 Isoxazoline derivate und ihre verwendung als antimikroben ATE227277T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2428796P 1996-08-21 1996-08-21
PCT/US1997/013934 WO1998007708A1 (en) 1996-08-21 1997-08-15 Isoxazoline derivatives useful as antimicrobials

Publications (1)

Publication Number Publication Date
ATE227277T1 true ATE227277T1 (de) 2002-11-15

Family

ID=21819822

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97937156T ATE227277T1 (de) 1996-08-21 1997-08-15 Isoxazoline derivate und ihre verwendung als antimikroben

Country Status (10)

Country Link
US (2) US5990136A (OSRAM)
EP (1) EP0920421B1 (OSRAM)
JP (1) JP2000516245A (OSRAM)
AT (1) ATE227277T1 (OSRAM)
AU (1) AU3973697A (OSRAM)
DE (1) DE69716925T2 (OSRAM)
DK (1) DK0920421T3 (OSRAM)
ES (1) ES2186916T3 (OSRAM)
PT (1) PT920421E (OSRAM)
WO (1) WO1998007708A1 (OSRAM)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9609919D0 (en) * 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
RU2208613C2 (ru) 1997-05-30 2003-07-20 Фармация Энд Апджон Компани Оксазолидиноновые антибактериальные агенты, содержащие тиокарбонильную функциональную группу
US6255304B1 (en) 1997-05-30 2001-07-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
DE69902634T2 (de) * 1998-02-13 2003-04-24 Pharmacia & Upjohn Co., Kalamazoo Substituierte aminophenylisoxazolinderivate verwendbar als antimikrobielle agenzien
CA2318762A1 (en) * 1998-02-25 1999-09-02 Richard Charles Thomas Substituted aminomethyl isoxazoline derivatives useful as antimicrobials
CA2333332A1 (en) 1998-06-05 1999-12-16 Astrazeneca Ab Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
US6420349B1 (en) 1998-08-24 2002-07-16 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
TW572757B (en) * 1998-08-24 2004-01-21 Bristol Myers Squibb Co Novel isoxazolinone antibacterial agents
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
US6465456B2 (en) 2000-06-29 2002-10-15 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
ES2256331T3 (es) 2000-12-21 2006-07-16 PHARMACIA & UPJOHN COMPANY LLC Derivados de quinolina antimicrobianos y uso de los mismos para tratar infecciones bacterianas.
JPWO2002053523A1 (ja) * 2000-12-26 2004-04-30 財団法人乙卯研究所 トロポロン誘導体
US7022705B2 (en) 2001-10-25 2006-04-04 Astrazeneca Ab Isoxazoline derivatives useful as antimicrobials
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
US7141588B2 (en) * 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
WO2004069832A2 (en) * 2003-02-07 2004-08-19 Warner-Lambert Company Llc Antibacterial agents
JP2006516989A (ja) * 2003-02-07 2006-07-13 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 抗菌剤として使用するための二環式環によりｎ−置換されたオキサゾリジノン誘導体
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
WO2005082900A2 (en) * 2004-01-28 2005-09-09 Pharmacia & Upjohn Company Llc Oxazolidinone amidoximes as antibacterial agents
EP1781643A1 (en) * 2004-08-06 2007-05-09 Pharmacia & Upjohn Company LLC Oxindole oxazolidinones as antibacterial agents
RU2392273C2 (ru) * 2004-09-10 2010-06-20 Синджента Лимитед Замещенные изоксазолы в качестве фунгицидов
PH12013500164A1 (en) * 2010-08-05 2015-07-08 Zoetis Services Llc Isoxazoline derivatives as antiparasitic agents
CA2822357A1 (en) 2010-12-22 2012-06-28 Abbvie Inc. Hepatitis c inhibitors and uses thereof
AU2013327663B2 (en) * 2012-10-03 2016-03-10 Shell Internationale Research Maatschappij B.V. Optimizing performance of a drilling assembly
WO2021000297A1 (en) 2019-07-03 2021-01-07 Merck Sharp & Dohme Corp. Compounds and methods of use thereof as antibacterial agents

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL137326C (OSRAM) * 1967-08-26
US4283403A (en) * 1976-06-14 1981-08-11 Eli Lilly And Company Substituted isoxazolines for control of plant phytopathogens
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
CZ288788B6 (cs) * 1992-12-08 2001-09-12 Pharmacia & Upjohn Company Antibakteriální fenyloxazolidinony substituované troponem
DE69422061T2 (de) * 1993-11-26 2000-03-30 Pfizer, Inc. 3-phenyl-2-isoxazoline derivate als entzündugshemmende mittel
DE4425612A1 (de) * 1994-07-20 1996-04-04 Bayer Ag 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
DE4425613A1 (de) * 1994-07-20 1996-01-25 Bayer Ag 5-gliedrige Heteroaryl-oxazolidinone
US5710159A (en) * 1996-05-09 1998-01-20 The Dupont Merck Pharmaceutical Company Integrin receptor antagonists

Also Published As

Publication number Publication date
US6093736A (en) 2000-07-25
EP0920421B1 (en) 2002-11-06
AU3973697A (en) 1998-03-06
DE69716925T2 (de) 2003-09-11
DK0920421T3 (da) 2003-03-10
JP2000516245A (ja) 2000-12-05
WO1998007708A1 (en) 1998-02-26
DE69716925D1 (de) 2002-12-12
PT920421E (pt) 2003-03-31
US5990136A (en) 1999-11-23
ES2186916T3 (es) 2003-05-16
EP0920421A1 (en) 1999-06-09

Similar Documents

Publication Publication Date Title
ATE227277T1 (de) Isoxazoline derivate und ihre verwendung als antimikroben
ATE269850T1 (de) 3-thiocarbamoylpyrazol-derivate als pestiziden
NO995846D0 (no) Oksazolidinon-antibakterielle midler med en tiokarbonylfunksjonalitet
ATE241621T1 (de) Arylsulfonyle als faktor xa inhibitoren
UY26551A1 (es) " agentes antibacterianos de 3-aminoquinazolin-2,4,dionas".
DE69823344D1 (de) Substituierte benzimidazol-derivaten und ihre verwendung zur behandlung retroviraler infektionen
PT1453512E (pt) Derivados de acetileno tendo actividade antagonistica do mglur 5
DE69910831D1 (de) Epothilonderivate und ihre verwendung als antitumormittel
DE60001241D1 (de) Heterocyclisch substituierte Isoxazolidine und ihre Verwendung als Fungizide
BG106390A (en) Novel spiro compounds
TR200201205T2 (tr) N-ikame edilmiş karbamoiloksialkil-azolyum türevleri.
ATE302775T1 (de) Carbolinderivate
ATE427300T1 (de) Heterocyclisch substituierte amide als calpainhemmer
ATE230392T1 (de) Amidinophenyl-pyrrolidine, -pyrroline und - isoxazolidine und ihre derivate
BR9711586A (pt) Compostos e uso dos mesmo
DE60121461D1 (de) Kondensierte pyridoindolderivate
ATE346067T1 (de) Carbolinderivate
ES2195397T3 (es) Quinazolin-2,4-dionas sustituidas en posicion 7 utiles como agentes antibacterianos.
DK0971922T3 (da) Tetrahydropyrido-forbindelser
DE60112960D1 (de) Kondensierte pyridoindolderivate
BG105710A (en) 5ht1 antagonists for antidepressant therapy
ATE321760T1 (de) N-aryl-2-oxazolidinone und deren derivate
ATE218138T1 (de) N-substituierte azabicycloheptan-derivate, ihre herstellung und verwendung
DE59810106D1 (de) Substituierte 2,4-diamino-1,3,5-triazine
DE69915688D1 (de) Benzonaphtyridin-1,8 derivate

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0920421

Country of ref document: EP

REN Ceased due to non-payment of the annual fee