ATE223722T1 - Verfahren zur herstellung von efonidipinhaltigen arzneimitteln - Google Patents
Verfahren zur herstellung von efonidipinhaltigen arzneimittelnInfo
- Publication number
- ATE223722T1 ATE223722T1 AT97907336T AT97907336T ATE223722T1 AT E223722 T1 ATE223722 T1 AT E223722T1 AT 97907336 T AT97907336 T AT 97907336T AT 97907336 T AT97907336 T AT 97907336T AT E223722 T1 ATE223722 T1 AT E223722T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- mixture
- water
- efonidipine
- efonidipine hydrochloride
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8886896 | 1996-03-18 | ||
| JP8886996 | 1996-03-18 | ||
| PCT/JP1997/000842 WO1997034610A1 (en) | 1996-03-18 | 1997-03-17 | Process for producing efonidipine hydrochloride preparations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE223722T1 true ATE223722T1 (de) | 2002-09-15 |
Family
ID=26430207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97907336T ATE223722T1 (de) | 1996-03-18 | 1997-03-17 | Verfahren zur herstellung von efonidipinhaltigen arzneimitteln |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6171599B1 (de) |
| EP (1) | EP0893999B8 (de) |
| KR (1) | KR100457273B1 (de) |
| AT (1) | ATE223722T1 (de) |
| AU (1) | AU1941897A (de) |
| CA (1) | CA2248582C (de) |
| DE (1) | DE69715395T2 (de) |
| ES (1) | ES2184063T3 (de) |
| PT (1) | PT893999E (de) |
| TW (1) | TW487574B (de) |
| WO (1) | WO1997034610A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0901786B1 (de) | 1997-08-11 | 2007-06-13 | Pfizer Products Inc. | Feste pharmazeutische Dispersionen mit erhöhter Bioverfügbarkeit |
| ZA200502496B (en) * | 2002-02-28 | 2005-10-12 | Japan Tobacco Inc | Ester compound and medicinal use thereof. |
| EP1669345A4 (de) * | 2003-08-29 | 2008-02-20 | Japan Tobacco Inc | Esterderivate und deren medizinische verwendung |
| US20060030623A1 (en) * | 2004-07-16 | 2006-02-09 | Noboru Furukawa | Agent for the treatment or prevention of diabetes, obesity or arteriosclerosis |
| JP4509118B2 (ja) * | 2004-10-06 | 2010-07-21 | エルメッド エーザイ株式会社 | 医薬組成物及びその製造方法、並びに医薬組成物におけるジヒドロピリジン系化合物の安定化方法 |
| US8101774B2 (en) * | 2004-10-18 | 2012-01-24 | Japan Tobacco Inc. | Ester derivatives and medicinal use thereof |
| WO2006046623A1 (ja) * | 2004-10-25 | 2006-05-04 | Japan Tobacco Inc. | 溶解性及び安定性の改善された固形製剤及びその製造方法 |
| WO2006118210A1 (ja) * | 2005-04-28 | 2006-11-09 | Eisai R & D Management Co., Ltd. | ジヒドロピリジン系化合物の分解を防止する方法 |
| WO2007108463A1 (ja) | 2006-03-23 | 2007-09-27 | Shionogi & Co., Ltd. | 溶解性が改善された固形製剤 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1016063B (zh) | 1986-01-22 | 1992-04-01 | 日产化学工业株式会社 | 二氢吡啶-5-膦酸环亚丙基酯的制备 |
| JP2528706B2 (ja) * | 1988-05-30 | 1996-08-28 | ゼリア新薬工業株式会社 | ジヒドロピリジン化合物の製剤組成物 |
-
1997
- 1997-03-17 US US09/142,208 patent/US6171599B1/en not_active Expired - Fee Related
- 1997-03-17 DE DE69715395T patent/DE69715395T2/de not_active Expired - Fee Related
- 1997-03-17 KR KR10-1998-0707339A patent/KR100457273B1/ko not_active IP Right Cessation
- 1997-03-17 PT PT97907336T patent/PT893999E/pt unknown
- 1997-03-17 AU AU19418/97A patent/AU1941897A/en not_active Abandoned
- 1997-03-17 ES ES97907336T patent/ES2184063T3/es not_active Expired - Lifetime
- 1997-03-17 CA CA002248582A patent/CA2248582C/en not_active Expired - Fee Related
- 1997-03-17 AT AT97907336T patent/ATE223722T1/de not_active IP Right Cessation
- 1997-03-17 TW TW086103291A patent/TW487574B/zh not_active IP Right Cessation
- 1997-03-17 EP EP97907336A patent/EP0893999B8/de not_active Expired - Lifetime
- 1997-03-17 WO PCT/JP1997/000842 patent/WO1997034610A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR100457273B1 (ko) | 2005-04-08 |
| KR20000064632A (ko) | 2000-11-06 |
| EP0893999A1 (de) | 1999-02-03 |
| PT893999E (pt) | 2002-12-31 |
| WO1997034610A1 (en) | 1997-09-25 |
| EP0893999B1 (de) | 2002-09-11 |
| DE69715395D1 (de) | 2002-10-17 |
| CA2248582C (en) | 2005-06-14 |
| DE69715395T2 (de) | 2003-05-15 |
| US6171599B1 (en) | 2001-01-09 |
| EP0893999B8 (de) | 2003-01-02 |
| ES2184063T3 (es) | 2003-04-01 |
| AU1941897A (en) | 1997-10-10 |
| CA2248582A1 (en) | 1997-09-25 |
| TW487574B (en) | 2002-05-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69600622D1 (de) | Bilden von lösungen von cellulose in wässrigem tertiärem aminoxid | |
| ATE223722T1 (de) | Verfahren zur herstellung von efonidipinhaltigen arzneimitteln | |
| FI971932A (fi) | Menetelmä pesu- ja puhdistusainetablettien valmistamiseksi mikroaalto- ja kuumailmakäsittelyllä | |
| ATE88062T1 (de) | Verfahren zur herstellung von getrockneten teigwaren. | |
| JPS6437274A (en) | Tobacco leave treatment method and apparatus | |
| ATE375236T2 (de) | Verfahren zur herstellung von gehärteten produkten | |
| DE3778073D1 (de) | Verfahren zur herstellung von kohle- oder koksbriketts. | |
| KR950024707A (ko) | 홍삼제조방법 | |
| PT1144169E (pt) | Dispositivo e processo destinado ao tratamento de material plastico | |
| DE69600958T2 (de) | Verfahren zur Herstellung von 1-Beta-D-Arabinofuranosylcytosine | |
| KR950011928B1 (ko) | 사문석을 주제로한 흡착제 제조방법 | |
| KR970033018A (ko) | 코크스공장의 부산물을 이용한 흡착제 제조방법 | |
| DE69113480D1 (de) | Verfahren zur Herstellung von getrocknetem Kollagen. | |
| DE68900524D1 (de) | Verfahren zur herstellung von benzylmerkaptan. | |
| KR890001464A (ko) | 제라틴을 이용한 건포류의 연질화 방법 | |
| ES482750A1 (es) | Procedimiento para fabricar carbon activo | |
| GB2000146A (en) | Stabilisation of nitrocellulose after pressure boiling | |
| ATE3399T1 (de) | Verfahren und vorrichtung zur behandlung eines einer dampfreformierung zu unterwerfenden kohlenwasserstoffstromes. | |
| JPS61199798A (ja) | カルサミンの製造方法 | |
| SE8101258L (sv) | Forfarande for framstellning av sjelvupplosande kirurgiska tradar | |
| SE9804024L (sv) | Förfarande för behandling av svartlut | |
| BG51518A1 (en) | Method for cellulose controlled destruction |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |