PT893999E - Processo para a producao para a producao de preparacoes de cloridrato de efonidipina - Google Patents
Processo para a producao para a producao de preparacoes de cloridrato de efonidipinaInfo
- Publication number
- PT893999E PT893999E PT97907336T PT97907336T PT893999E PT 893999 E PT893999 E PT 893999E PT 97907336 T PT97907336 T PT 97907336T PT 97907336 T PT97907336 T PT 97907336T PT 893999 E PT893999 E PT 893999E
- Authority
- PT
- Portugal
- Prior art keywords
- treatment
- production
- efonidipine
- mixture
- water
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8886896 | 1996-03-18 | ||
| JP8886996 | 1996-03-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT893999E true PT893999E (pt) | 2002-12-31 |
Family
ID=26430207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97907336T PT893999E (pt) | 1996-03-18 | 1997-03-17 | Processo para a producao para a producao de preparacoes de cloridrato de efonidipina |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6171599B1 (pt) |
| EP (1) | EP0893999B8 (pt) |
| KR (1) | KR100457273B1 (pt) |
| AT (1) | ATE223722T1 (pt) |
| AU (1) | AU1941897A (pt) |
| CA (1) | CA2248582C (pt) |
| DE (1) | DE69715395T2 (pt) |
| ES (1) | ES2184063T3 (pt) |
| PT (1) | PT893999E (pt) |
| TW (1) | TW487574B (pt) |
| WO (1) | WO1997034610A1 (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0901786T3 (da) | 1997-08-11 | 2007-10-08 | Pfizer Prod Inc | Faste farmaceutiske dispersioner med foröget biotilgængelighed |
| KR100717098B1 (ko) * | 2002-02-28 | 2007-05-10 | 니뽄 다바코 산교 가부시키가이샤 | 에스테르 화합물 및 그 의약 용도 |
| EP1669345A4 (en) * | 2003-08-29 | 2008-02-20 | Japan Tobacco Inc | ESTER DERIVATIVE AND MEDICAL USE THEREOF |
| US20060030623A1 (en) * | 2004-07-16 | 2006-02-09 | Noboru Furukawa | Agent for the treatment or prevention of diabetes, obesity or arteriosclerosis |
| DE602005018387D1 (de) * | 2004-10-06 | 2010-01-28 | Eisai R&D Man Co Ltd | Medizinische zusammensetzung, verfahren zu ihrer hdihydropyridin-verbindung in einer medizinischen zusammensetzung |
| US8101774B2 (en) * | 2004-10-18 | 2012-01-24 | Japan Tobacco Inc. | Ester derivatives and medicinal use thereof |
| MX2007004973A (es) * | 2004-10-25 | 2007-06-14 | Japan Tobacco Inc | Formulacion solida con solubilidad y estabilidad mejoradas y metodo para producir la formulacion. |
| WO2006118210A1 (ja) * | 2005-04-28 | 2006-11-09 | Eisai R & D Management Co., Ltd. | ジヒドロピリジン系化合物の分解を防止する方法 |
| US8133513B2 (en) | 2006-03-23 | 2012-03-13 | Shionogi & Co., Ltd. | Solid preparation having improved solubility |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1016063B (zh) | 1986-01-22 | 1992-04-01 | 日产化学工业株式会社 | 二氢吡啶-5-膦酸环亚丙基酯的制备 |
| JP2528706B2 (ja) | 1988-05-30 | 1996-08-28 | ゼリア新薬工業株式会社 | ジヒドロピリジン化合物の製剤組成物 |
-
1997
- 1997-03-17 WO PCT/JP1997/000842 patent/WO1997034610A1/en not_active Application Discontinuation
- 1997-03-17 EP EP97907336A patent/EP0893999B8/en not_active Expired - Lifetime
- 1997-03-17 AT AT97907336T patent/ATE223722T1/de not_active IP Right Cessation
- 1997-03-17 DE DE69715395T patent/DE69715395T2/de not_active Expired - Fee Related
- 1997-03-17 TW TW086103291A patent/TW487574B/zh not_active IP Right Cessation
- 1997-03-17 KR KR10-1998-0707339A patent/KR100457273B1/ko not_active IP Right Cessation
- 1997-03-17 AU AU19418/97A patent/AU1941897A/en not_active Abandoned
- 1997-03-17 US US09/142,208 patent/US6171599B1/en not_active Expired - Fee Related
- 1997-03-17 ES ES97907336T patent/ES2184063T3/es not_active Expired - Lifetime
- 1997-03-17 CA CA002248582A patent/CA2248582C/en not_active Expired - Fee Related
- 1997-03-17 PT PT97907336T patent/PT893999E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2248582A1 (en) | 1997-09-25 |
| CA2248582C (en) | 2005-06-14 |
| ES2184063T3 (es) | 2003-04-01 |
| ATE223722T1 (de) | 2002-09-15 |
| DE69715395T2 (de) | 2003-05-15 |
| WO1997034610A1 (en) | 1997-09-25 |
| TW487574B (en) | 2002-05-21 |
| EP0893999B1 (en) | 2002-09-11 |
| EP0893999B8 (en) | 2003-01-02 |
| KR100457273B1 (ko) | 2005-04-08 |
| DE69715395D1 (de) | 2002-10-17 |
| KR20000064632A (ko) | 2000-11-06 |
| EP0893999A1 (en) | 1999-02-03 |
| AU1941897A (en) | 1997-10-10 |
| US6171599B1 (en) | 2001-01-09 |
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