PT893999E - Processo para a producao para a producao de preparacoes de cloridrato de efonidipina - Google Patents
Processo para a producao para a producao de preparacoes de cloridrato de efonidipinaInfo
- Publication number
- PT893999E PT893999E PT97907336T PT97907336T PT893999E PT 893999 E PT893999 E PT 893999E PT 97907336 T PT97907336 T PT 97907336T PT 97907336 T PT97907336 T PT 97907336T PT 893999 E PT893999 E PT 893999E
- Authority
- PT
- Portugal
- Prior art keywords
- treatment
- production
- efonidipine
- mixture
- water
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8886896 | 1996-03-18 | ||
JP8886996 | 1996-03-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT893999E true PT893999E (pt) | 2002-12-31 |
Family
ID=26430207
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT97907336T PT893999E (pt) | 1996-03-18 | 1997-03-17 | Processo para a producao para a producao de preparacoes de cloridrato de efonidipina |
Country Status (11)
Country | Link |
---|---|
US (1) | US6171599B1 (pt) |
EP (1) | EP0893999B8 (pt) |
KR (1) | KR100457273B1 (pt) |
AT (1) | ATE223722T1 (pt) |
AU (1) | AU1941897A (pt) |
CA (1) | CA2248582C (pt) |
DE (1) | DE69715395T2 (pt) |
ES (1) | ES2184063T3 (pt) |
PT (1) | PT893999E (pt) |
TW (1) | TW487574B (pt) |
WO (1) | WO1997034610A1 (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT901786E (pt) | 1997-08-11 | 2007-08-07 | Pfizer Prod Inc | Disperções farmacêuticas sólidas com biodisponibilidade melhorada |
NZ531890A (en) * | 2002-02-28 | 2006-02-24 | Japan Tobacco Inc | Ester compound and medicinal use thereof |
WO2005021486A1 (ja) * | 2003-08-29 | 2005-03-10 | Japan Tobacco Inc. | エステル誘導体及びその医薬用途 |
US20060030623A1 (en) * | 2004-07-16 | 2006-02-09 | Noboru Furukawa | Agent for the treatment or prevention of diabetes, obesity or arteriosclerosis |
JP4509118B2 (ja) * | 2004-10-06 | 2010-07-21 | エルメッド エーザイ株式会社 | 医薬組成物及びその製造方法、並びに医薬組成物におけるジヒドロピリジン系化合物の安定化方法 |
US8101774B2 (en) * | 2004-10-18 | 2012-01-24 | Japan Tobacco Inc. | Ester derivatives and medicinal use thereof |
CA2582767C (en) * | 2004-10-25 | 2011-05-24 | Japan Tobacco Inc. | Solid formulation with improved solubility and stability and method for producing said formulation |
WO2006118210A1 (ja) * | 2005-04-28 | 2006-11-09 | Eisai R & D Management Co., Ltd. | ジヒドロピリジン系化合物の分解を防止する方法 |
JPWO2007108463A1 (ja) | 2006-03-23 | 2009-08-06 | 塩野義製薬株式会社 | 溶解性が改善された固形製剤 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1016063B (zh) * | 1986-01-22 | 1992-04-01 | 日产化学工业株式会社 | 二氢吡啶-5-膦酸环亚丙基酯的制备 |
JP2528706B2 (ja) * | 1988-05-30 | 1996-08-28 | ゼリア新薬工業株式会社 | ジヒドロピリジン化合物の製剤組成物 |
-
1997
- 1997-03-17 DE DE69715395T patent/DE69715395T2/de not_active Expired - Fee Related
- 1997-03-17 KR KR10-1998-0707339A patent/KR100457273B1/ko not_active IP Right Cessation
- 1997-03-17 ES ES97907336T patent/ES2184063T3/es not_active Expired - Lifetime
- 1997-03-17 TW TW086103291A patent/TW487574B/zh not_active IP Right Cessation
- 1997-03-17 AT AT97907336T patent/ATE223722T1/de not_active IP Right Cessation
- 1997-03-17 AU AU19418/97A patent/AU1941897A/en not_active Abandoned
- 1997-03-17 EP EP97907336A patent/EP0893999B8/en not_active Expired - Lifetime
- 1997-03-17 PT PT97907336T patent/PT893999E/pt unknown
- 1997-03-17 CA CA002248582A patent/CA2248582C/en not_active Expired - Fee Related
- 1997-03-17 US US09/142,208 patent/US6171599B1/en not_active Expired - Fee Related
- 1997-03-17 WO PCT/JP1997/000842 patent/WO1997034610A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2248582C (en) | 2005-06-14 |
AU1941897A (en) | 1997-10-10 |
ES2184063T3 (es) | 2003-04-01 |
ATE223722T1 (de) | 2002-09-15 |
EP0893999B1 (en) | 2002-09-11 |
US6171599B1 (en) | 2001-01-09 |
DE69715395D1 (de) | 2002-10-17 |
KR20000064632A (ko) | 2000-11-06 |
KR100457273B1 (ko) | 2005-04-08 |
CA2248582A1 (en) | 1997-09-25 |
DE69715395T2 (de) | 2003-05-15 |
TW487574B (en) | 2002-05-21 |
EP0893999B8 (en) | 2003-01-02 |
EP0893999A1 (en) | 1999-02-03 |
WO1997034610A1 (en) | 1997-09-25 |
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