ATE222958T1 - Behandlung von glucanen mit enzymen - Google Patents
Behandlung von glucanen mit enzymenInfo
- Publication number
- ATE222958T1 ATE222958T1 AT95914485T AT95914485T ATE222958T1 AT E222958 T1 ATE222958 T1 AT E222958T1 AT 95914485 T AT95914485 T AT 95914485T AT 95914485 T AT95914485 T AT 95914485T AT E222958 T1 ATE222958 T1 AT E222958T1
- Authority
- AT
- Austria
- Prior art keywords
- glucan
- treatment
- yeast
- glucans
- enzymes
- Prior art date
Links
- 229920001503 Glucan Polymers 0.000 title abstract 5
- 102000004190 Enzymes Human genes 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 title 1
- 210000005253 yeast cell Anatomy 0.000 abstract 3
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 2
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 abstract 2
- 241000235070 Saccharomyces Species 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 210000000987 immune system Anatomy 0.000 abstract 1
- 230000007928 solubilization Effects 0.000 abstract 1
- 238000005063 solubilization Methods 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/42—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0208—Specific bacteria not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- General Engineering & Computer Science (AREA)
- Mycology (AREA)
- Inorganic Chemistry (AREA)
- Food Science & Technology (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Fodder In General (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO941581A NO300692B1 (no) | 1994-04-29 | 1994-04-29 | Solubilisert forgrenet ß-1,3-glukan og anvendelse derav samt anvendelse av usolubilisert forgrenet ß-1,3-glukan |
PCT/IB1995/000265 WO1995030022A1 (en) | 1994-04-29 | 1995-04-18 | Enzyme treatment of glucans |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE222958T1 true ATE222958T1 (de) | 2002-09-15 |
Family
ID=19897060
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95914485T ATE222958T1 (de) | 1994-04-29 | 1995-04-18 | Behandlung von glucanen mit enzymen |
Country Status (12)
Country | Link |
---|---|
US (3) | US7883875B2 (de) |
EP (1) | EP0759089B1 (de) |
JP (3) | JP3992730B2 (de) |
AT (1) | ATE222958T1 (de) |
AU (1) | AU703251B2 (de) |
CA (1) | CA2189010C (de) |
DE (1) | DE69527955T2 (de) |
DK (1) | DK0759089T3 (de) |
ES (1) | ES2182898T3 (de) |
FI (1) | FI114807B (de) |
NO (1) | NO300692B1 (de) |
WO (1) | WO1995030022A1 (de) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO300692B1 (no) | 1994-04-29 | 1997-07-07 | Biotec Mackzymal As | Solubilisert forgrenet ß-1,3-glukan og anvendelse derav samt anvendelse av usolubilisert forgrenet ß-1,3-glukan |
US5786343A (en) * | 1997-03-05 | 1998-07-28 | Immudyne, Inc. | Phagocytosis activator compositions and their use |
US8912165B2 (en) | 1999-03-12 | 2014-12-16 | Biotec Pharmacon Asa | Methods of skin treatment and use of water-soluble β-(1,3) glucans as active agents for producing therapeutic skin treatment agents |
US6875754B1 (en) | 1999-03-12 | 2005-04-05 | Biotec Asa | Use of water-soluble β-(1,3) glucans as agents for producing therapeutic skin treatment agents |
DE19911055A1 (de) * | 1999-03-12 | 2000-09-21 | Cognis Deutschland Gmbh | Verwendung von oberflächenaktiven Gemischen |
DE19911052A1 (de) | 1999-03-12 | 2000-09-21 | Cognis Deutschland Gmbh | Sonnenschutzmittel |
DE19911058B4 (de) * | 1999-03-12 | 2004-09-30 | Biotec Asa | Verwendung von nanoskaligen wasserlöslichen β-(1,3)-Glucanen |
US8501710B2 (en) * | 1999-03-12 | 2013-08-06 | Biotec Pharmacon Asa | Methods of skin treatment and use of water-soluble β-(1,3) glucans as active agents for producing therapeutic skin treatment agents |
DE19911057C2 (de) * | 1999-03-12 | 2001-01-25 | Cognis Deutschland Gmbh | Haarkosmetische Zubereitungen |
DE19911056B9 (de) * | 1999-03-12 | 2005-09-08 | Biotec Asa | Kosmetische Zubereitungen und deren Verwendung |
DE19911053B4 (de) | 1999-03-12 | 2004-10-28 | Biotec Asa | Kosmetische und/oder pharmazeutische Zubereitungen |
DE19917743C2 (de) * | 1999-04-20 | 2003-08-14 | Biotec Asa | Desodorierende Zubereitungen |
DE19917744A1 (de) * | 1999-04-20 | 2000-10-26 | Cognis Deutschland Gmbh | Dekorative kosmetische Zubereitungen |
DE19920557B4 (de) * | 1999-05-05 | 2004-09-09 | Biotec Asa | Verfahren zur Herstellung von Kollagenfreien kosmetischen Zubereitungen |
US20020009463A1 (en) * | 2000-02-23 | 2002-01-24 | Jan Raa | Novel, non-antigenic, mucosal adjuvant formulation which enhances the effects of substances, including vaccine antigens, in contact with mucosal body surfaces |
US7906492B2 (en) | 2001-01-16 | 2011-03-15 | Sloan-Kettering Institute For Cancer Research | Therapy-enhancing glucan |
US7507724B2 (en) | 2001-01-16 | 2009-03-24 | Sloan-Kettering Institute For Cancer Research | Therapy-enhancing glucan |
BE1014638A6 (fr) | 2002-02-12 | 2004-02-03 | Univ Liege | Methode de preparation de derives de la paroi cellulaire a partir de biomasse. |
GB0211118D0 (en) | 2002-05-15 | 2002-06-26 | Polonelli Luciano | Vaccines |
US7018986B2 (en) * | 2002-09-20 | 2006-03-28 | Immudyne | Use of beta glucans for the treatment of osteoporosis and other diseases of bone resorption |
US20050180964A1 (en) | 2003-03-17 | 2005-08-18 | Puntenney Steven B. | Methods and compositions for the inhibition of growth of infectious Aspergillus fumigatus and other mycotic organisms in the gut of mammalian and avian species |
JP2004210895A (ja) * | 2002-12-27 | 2004-07-29 | Immudyne Japan:Kk | 免疫機能を有する可能性β−グルカンの製造方法及び用途 |
DE602004020117D1 (de) | 2004-02-13 | 2009-04-30 | Alpron Co Ltd | Verfahren zur herstellung von aus hefe stammendem glucan |
US20050220846A1 (en) | 2004-04-05 | 2005-10-06 | Puntenney Steven B | Use of beta-1,3 (4)-endoglucanohydrolase, beta-1,3 (4) glucan, diatomaceous earth, mineral clay and glucomannan to augment immune function |
AU2004218698B2 (en) * | 2004-10-08 | 2011-06-09 | Biotec BetaGlucans AS | Method |
JP4570949B2 (ja) * | 2004-12-13 | 2010-10-27 | 株式会社アルプロン | 酵母由来グルカンの製造方法 |
BRPI0520481B1 (pt) * | 2005-08-10 | 2020-11-10 | Steven Bruce Puntenney | composição de b-1, 3 (4) - endoglucanohidrolase, b-1, 3 (4) glucanas, terra diatomácea, argila mineral e glucomananas e método de uso para aumentar a função imunológica |
EP1984004A4 (de) * | 2006-01-17 | 2010-03-03 | Sloan Kettering Inst Cancer | Die therapie verstärkendes glucan |
US8323644B2 (en) | 2006-01-17 | 2012-12-04 | Sloan-Kettering Institute For Cancer Research | Therapy-enhancing glucan |
US8142798B2 (en) | 2006-04-26 | 2012-03-27 | OmniGen Research, L.L.C. | Augmentation of titer for vaccination in animals |
US8580253B2 (en) * | 2006-11-06 | 2013-11-12 | Whitehead Institute | Immunomodulating compositions and methods of use |
US9457047B2 (en) | 2006-11-06 | 2016-10-04 | Whitehead Institute | Immunomodulating compositions and methods of use thereof |
WO2008102151A1 (en) * | 2007-02-21 | 2008-08-28 | Biotec Pharmacon Asa | Medical uses of glucans |
CN101711112B (zh) * | 2007-05-08 | 2015-11-25 | 生物高聚物工程公司Dba生物治疗公司 | 粒状可溶的葡聚糖制备 |
FI20070471A0 (fi) * | 2007-06-13 | 2007-06-13 | Glykos Finland Oy | Ravinnelisäkompositiota |
EP2211900A1 (de) * | 2007-11-19 | 2010-08-04 | Calanus AS | Bioaktive ruderfusskrebs-zusammensetzungen, verfahren zu ihrer herstellung und ihre verwendung zur verhinderung oder behandlung der infektion von wirten durch phylogenetisch ähnliche ektoparasiten |
US9439954B2 (en) | 2007-11-26 | 2016-09-13 | Glaxosmithkline Biologicals Sa | Conjugated beta-1,3-linked glucans |
BRPI0900639C1 (pt) * | 2009-02-13 | 2011-12-20 | Hebron Farmaceutica Pesquisa Desenvolvimento E Inovacao Tecnologica Ltda | composição farmacêutica e uso desta para tratamento e/ou prevenção de doenças do trato respiratório |
PT3130396T (pt) | 2009-03-27 | 2021-05-12 | Bend Res Inc | Processo de secagem por pulverização |
WO2012014978A1 (ja) * | 2010-07-29 | 2012-02-02 | 国立大学法人北海道大学 | 免疫アジュバント |
WO2012031129A2 (en) | 2010-09-03 | 2012-03-08 | Bend Research, Inc. | Spray-drying apparatus and methods of using the same |
US9084944B2 (en) | 2010-09-03 | 2015-07-21 | Bend Research, Inc. | Spray-drying apparatus and methods of using the same |
EP2618924A1 (de) | 2010-09-24 | 2013-07-31 | Bend Research, Inc. | Hochtemperatur-sprühtrocknungsverfahren und verfahren |
GB201020193D0 (en) | 2010-11-29 | 2011-01-12 | Biotec Pharmacon Asa | Glucan compositions |
GB201020191D0 (en) | 2010-11-29 | 2011-01-12 | Biotec Pharmacon Asa | Glucan gels |
GB201020190D0 (en) | 2010-11-29 | 2011-01-12 | Biotec Pharmacon Asa | Glucans |
WO2012120290A2 (en) | 2011-03-04 | 2012-09-13 | Sana Pharma As | Cosmetic formulations |
FR2981075A1 (fr) | 2011-10-11 | 2013-04-12 | Kitozyme | Procede de preparation de glucans a partir d'aspergillus niger |
MD4329C1 (ro) * | 2013-10-30 | 2015-09-30 | Институт Микробиологии И Биотехнологии Академии Наук Молдовы | Procedeu de cultivare a tulpinii de levuri Saccharomyces cerevisiae CNMN-Y-20 |
WO2015123456A1 (en) | 2014-02-12 | 2015-08-20 | OmniGen Research, L.L.C. | Composition and method for promoting reduction of heat stress in animals |
CA2962719A1 (en) | 2014-10-31 | 2016-05-06 | Bend Research Inc. | Process for forming active domains dispersed in a matrix |
WO2017044832A1 (en) | 2015-09-09 | 2017-03-16 | Omnigen Research, Llc | A composition and/or combination for aquaculture |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2764463A (en) | 1953-05-26 | 1956-09-25 | Underwood Corp | Magnetic recording system |
US3954979A (en) * | 1972-11-24 | 1976-05-04 | Ceres Products Company, Inc. | Process for preparing stabilized yeast and compositions and tableting composition and method |
JPS5432076B2 (de) | 1973-09-14 | 1979-10-11 | ||
JPS54138115A (en) * | 1978-04-17 | 1979-10-26 | Kirin Brewery | Antiicancer agent |
GB2076418A (en) | 1980-05-22 | 1981-12-02 | Sankyo Co | Hydrolyzed polysaccharide |
JPS6019619B2 (ja) | 1980-09-19 | 1985-05-17 | 株式会社日立製作所 | X線管用回転陽極 |
SE456911B (sv) | 1983-12-19 | 1988-11-14 | Olle Larm | Vattenloeslig, aminerad beta-1,3-bunden d-glukan och makrofagstimulerande komposition innehaallande densamma |
JPS60196195A (ja) | 1984-03-21 | 1985-10-04 | Dainippon Seito Kk | イ−ストグルカンの製造法 |
US4992540A (en) | 1984-11-28 | 1991-02-12 | Massachusetts Institute Of Technology | Glucan composition and process for preparation thereof |
US5082936A (en) | 1984-11-28 | 1992-01-21 | Massachusetts Institute Of Technology | Glucan composition and process for preparation thereof |
US5028703A (en) * | 1988-03-11 | 1991-07-02 | Massachusetts Institute Of Technology | Glucan composition and process for preparation thereof |
US4810646A (en) | 1984-11-28 | 1989-03-07 | Massachusetts Institute Of Technology | Glucan compositions and process for preparation thereof |
US5057503A (en) * | 1989-01-23 | 1991-10-15 | The Brigham And Women's Hospital | Derivativized polysaccharides with biologic activity, method of their isolation, and uses therefor |
CA1330303C (en) | 1989-02-20 | 1994-06-21 | Libor Henry Nikl | Composition and process to enhance the efficacy of a fish vaccine |
US5488040A (en) * | 1989-09-08 | 1996-01-30 | Alpha-Beta Technology, Inc. | Use of neutral soluble glucan preparations to stimulate platelet production |
US5622939A (en) * | 1992-08-21 | 1997-04-22 | Alpha-Beta Technology, Inc. | Glucan preparation |
JPH05502018A (ja) * | 1989-09-08 | 1993-04-15 | アルファ ベータ テクノロジー,インコーポレイティッド | 免疫系活性化方法 |
JPH05503952A (ja) * | 1989-09-08 | 1993-06-24 | アルファ ベータ テクノロジー,インコーポレイティッド | 可溶性グルカン類の製造方法 |
US6020324A (en) * | 1989-10-20 | 2000-02-01 | The Collaborative Group, Ltd. | Glucan dietary additives |
CA2040374C (en) * | 1990-07-06 | 1998-06-16 | Gunnar Rorstad | Process for enhancing the resistance of aquatic animals to disease |
NO300692B1 (no) | 1994-04-29 | 1997-07-07 | Biotec Mackzymal As | Solubilisert forgrenet ß-1,3-glukan og anvendelse derav samt anvendelse av usolubilisert forgrenet ß-1,3-glukan |
-
1994
- 1994-04-29 NO NO941581A patent/NO300692B1/no not_active IP Right Cessation
-
1995
- 1995-04-18 ES ES95914485T patent/ES2182898T3/es not_active Expired - Lifetime
- 1995-04-18 DE DE69527955T patent/DE69527955T2/de not_active Expired - Lifetime
- 1995-04-18 JP JP52809395A patent/JP3992730B2/ja not_active Expired - Lifetime
- 1995-04-18 WO PCT/IB1995/000265 patent/WO1995030022A1/en active IP Right Grant
- 1995-04-18 AU AU21464/95A patent/AU703251B2/en not_active Ceased
- 1995-04-18 CA CA2189010A patent/CA2189010C/en not_active Expired - Lifetime
- 1995-04-18 AT AT95914485T patent/ATE222958T1/de active
- 1995-04-18 DK DK95914485T patent/DK0759089T3/da active
- 1995-04-18 EP EP95914485A patent/EP0759089B1/de not_active Expired - Lifetime
-
1996
- 1996-10-28 FI FI964339A patent/FI114807B/fi not_active IP Right Cessation
-
2005
- 2005-03-30 US US11/093,427 patent/US7883875B2/en not_active Expired - Fee Related
-
2007
- 2007-05-16 JP JP2007130872A patent/JP2007228974A/ja active Pending
- 2007-12-06 US US11/951,811 patent/US8142785B2/en not_active Expired - Fee Related
-
2008
- 2008-11-13 JP JP2008290653A patent/JP2009051863A/ja active Pending
-
2010
- 2010-12-27 US US12/978,923 patent/US8252295B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
NO300692B1 (no) | 1997-07-07 |
JP2009051863A (ja) | 2009-03-12 |
JP3992730B2 (ja) | 2007-10-17 |
EP0759089A1 (de) | 1997-02-26 |
CA2189010C (en) | 2010-07-13 |
US8142785B2 (en) | 2012-03-27 |
DK0759089T3 (da) | 2003-01-06 |
FI964339A0 (fi) | 1996-10-28 |
NO941581D0 (de) | 1994-04-29 |
ES2182898T3 (es) | 2003-03-16 |
AU2146495A (en) | 1995-11-29 |
WO1995030022A1 (en) | 1995-11-09 |
FI964339A (fi) | 1996-10-28 |
AU703251B2 (en) | 1999-03-25 |
US8252295B2 (en) | 2012-08-28 |
FI114807B (fi) | 2004-12-31 |
DE69527955D1 (de) | 2002-10-02 |
US20080124349A1 (en) | 2008-05-29 |
JPH09512708A (ja) | 1997-12-22 |
US7883875B2 (en) | 2011-02-08 |
DE69527955T2 (de) | 2003-04-10 |
US20050255565A1 (en) | 2005-11-17 |
JP2007228974A (ja) | 2007-09-13 |
EP0759089B1 (de) | 2002-08-28 |
NO941581L (no) | 1995-10-30 |
CA2189010A1 (en) | 1995-11-09 |
US20110104208A1 (en) | 2011-05-05 |
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