ATE220203T1 - Nachweis einer substanz durch brechzahländerung - Google Patents

Nachweis einer substanz durch brechzahländerung

Info

Publication number
ATE220203T1
ATE220203T1 AT99908814T AT99908814T ATE220203T1 AT E220203 T1 ATE220203 T1 AT E220203T1 AT 99908814 T AT99908814 T AT 99908814T AT 99908814 T AT99908814 T AT 99908814T AT E220203 T1 ATE220203 T1 AT E220203T1
Authority
AT
Austria
Prior art keywords
substance
laser
detection
change
laser cavity
Prior art date
Application number
AT99908814T
Other languages
English (en)
Inventor
Lars Lading
Lars Lindvold
Original Assignee
Torsana Biosensor As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Torsana Biosensor As filed Critical Torsana Biosensor As
Application granted granted Critical
Publication of ATE220203T1 publication Critical patent/ATE220203T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N21/774—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01D—MEASURING NOT SPECIALLY ADAPTED FOR A SPECIFIC VARIABLE; ARRANGEMENTS FOR MEASURING TWO OR MORE VARIABLES NOT COVERED IN A SINGLE OTHER SUBCLASS; TARIFF METERING APPARATUS; MEASURING OR TESTING NOT OTHERWISE PROVIDED FOR
    • G01D5/00—Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable
    • G01D5/26—Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable characterised by optical transfer means, i.e. using infrared, visible, or ultraviolet light
    • G01D5/268—Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable characterised by optical transfer means, i.e. using infrared, visible, or ultraviolet light using optical fibres
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
    • G01N21/45—Refractivity; Phase-affecting properties, e.g. optical path length using interferometric methods; using Schlieren methods
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N21/7746—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the waveguide coupled to a cavity resonator
AT99908814T 1998-01-23 1999-01-22 Nachweis einer substanz durch brechzahländerung ATE220203T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK9198 1998-01-23
PCT/EP1999/000401 WO1999037996A1 (en) 1998-01-23 1999-01-22 Detection of a substance by refractive index change
US09/624,891 US6493090B1 (en) 1998-01-23 2000-07-24 Detection of a substance by refractive index change

Publications (1)

Publication Number Publication Date
ATE220203T1 true ATE220203T1 (de) 2002-07-15

Family

ID=26063288

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99908814T ATE220203T1 (de) 1998-01-23 1999-01-22 Nachweis einer substanz durch brechzahländerung

Country Status (8)

Country Link
US (1) US6493090B1 (de)
EP (1) EP1066507B1 (de)
JP (1) JP2002501190A (de)
AT (1) ATE220203T1 (de)
AU (1) AU2829499A (de)
DE (1) DE69902023T2 (de)
DK (1) DK1066507T3 (de)
WO (1) WO1999037996A1 (de)

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US7384797B1 (en) 2000-10-12 2008-06-10 University Of Utah Research Foundation Resonant optical cavities for high-sensitivity high-throughput biological sensors and methods
US7267797B1 (en) * 2000-11-14 2007-09-11 Cornell Research Foundation, Inc. Nanofabricated photon tunneling based sensor
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US6810066B2 (en) * 2002-02-20 2004-10-26 Agilent Technologies, Inc. Fiber-coupled tunable single-mode long-wavelength vertical-cavity laser
JP2004016609A (ja) * 2002-06-19 2004-01-22 Omron Healthcare Co Ltd 体液成分濃度測定方法及び体液成分濃度測定装置
AU2003265261A1 (en) * 2002-07-08 2004-01-23 Regents Of The University Of Colorado Optical olfactory sensor with holographic readout
US7619739B1 (en) * 2002-08-29 2009-11-17 Science Applications International Corporation Detection and identification of biological agents using Bragg filters
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US7149396B2 (en) * 2003-06-16 2006-12-12 The Regents Of The University Of California Apparatus for optical measurements on low-index non-solid materials based on arrow waveguides
US7447391B2 (en) * 2004-05-11 2008-11-04 Tel Aviv University Future Technology Ltd. Planar-resonator based optical chemo- and biosensor
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WO2006047408A2 (en) * 2004-10-22 2006-05-04 Vanderbilt University On-chip polarimetry for high-throughput screening of nanoliter and smaller sample volumes
US8178046B2 (en) * 2005-02-23 2012-05-15 Sierra Sensors Gmbh Microfluidic devices with SPR sensing capabilities
DE102005027023A1 (de) * 2005-06-11 2006-12-14 Gerhart Schroff Verfahren und Anordnung zur integralen Dichtheitsprüfung
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US7218802B1 (en) 2005-11-30 2007-05-15 Corning Incorporated Low drift planar waveguide grating sensor and method for manufacturing same
EP1998891B1 (de) 2006-03-20 2016-08-31 Koninklijke Philips N.V. System-in-package-plattform für elektronische mikrofluidische vorrichtungen
US7428055B2 (en) * 2006-10-05 2008-09-23 General Electric Company Interferometer-based real time early fouling detection system and method
US7602496B2 (en) * 2006-10-19 2009-10-13 Sporian Microsystems, Inc. Optical sensor with biologically reactive surface
US7652767B2 (en) * 2006-10-19 2010-01-26 Sporian Microsystems, Inc. Optical sensor with chemically reactive surface
US7746466B2 (en) * 2007-05-14 2010-06-29 The Regents Of The University Of California System and method for flow cytometry
US7835013B2 (en) * 2007-05-18 2010-11-16 Vanderbilt University Interferometric detection system and method
US8445217B2 (en) 2007-09-20 2013-05-21 Vanderbilt University Free solution measurement of molecular interactions by backscattering interferometry
WO2009103339A1 (en) * 2008-02-21 2009-08-27 Valtion Teknillinen Tutkimuskeskus Biosensor and a related manufacturing method
US7489835B1 (en) * 2008-03-28 2009-02-10 General Electric Company Sensing system with fiber gas sensor
EP2274445A2 (de) 2008-04-11 2011-01-19 University of Utah Research Foundation Verfahren und zusammensetzungen zur methylierungsanalyse auf basis eines quantitativen arrays
WO2010008789A2 (en) * 2008-06-23 2010-01-21 University Of South Florida Interferometric chemical sensor array
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DE102009013878B3 (de) * 2009-03-16 2010-05-20 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Sensoranordnung und Detektionsverfahren
JP5373478B2 (ja) * 2009-05-27 2013-12-18 日本航空電子工業株式会社 化学物質センサ
CN101694463B (zh) * 2009-10-19 2011-07-20 浙江大学 半导体激光内腔光微流生物传感器
US9772284B2 (en) 2010-04-20 2017-09-26 President And Fellows Of Harvard College Biomedical and chemical sensing with nanobeam photonic crystal cavities using optical bistability
US9638632B2 (en) 2010-06-11 2017-05-02 Vanderbilt University Multiplexed interferometric detection system and method
US8798414B2 (en) 2010-09-29 2014-08-05 President And Fellows Of Harvard College High quality factor photonic crystal nanobeam cavity and method of designing and making same
US9562853B2 (en) 2011-02-22 2017-02-07 Vanderbilt University Nonaqueous backscattering interferometric methods
US9273949B2 (en) 2012-05-11 2016-03-01 Vanderbilt University Backscattering interferometric methods
CN103018200B (zh) * 2012-11-30 2015-02-18 清华大学 透明介质折射率的监测装置及监测方法
US9553419B2 (en) 2014-08-22 2017-01-24 Bae Systems Information And Electronic Systems Integration Inc. Shared multi-wavelength laser resonator with gain selected output coupling
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CN107064012B (zh) 2017-04-11 2019-06-25 山西大学 基于拍频效应的石英增强光声光谱气体检测装置及方法
EP3821505A4 (de) * 2018-07-13 2022-07-06 The Government of the United States of America as represented by the Secretary of the Navy Hochstabile halbleiterlaser und sensoren für iii-v- und silicium-photonische integrierte schaltungen
WO2020023496A1 (en) * 2018-07-23 2020-01-30 The University Of Chicago Resonator-based ion-selective sensor
CN110514233B (zh) * 2019-10-10 2024-04-26 中国计量大学 一种空腔悬浮通道型光纤线上马赫-曾德干涉仪
CN113092385B (zh) * 2021-05-10 2022-03-22 山东大学 中高层大气折射率测量装置及测量方法
DE102021131644A1 (de) 2021-12-01 2023-06-01 Carl Zeiss Ag Diffraktiver PIC Sensor

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Also Published As

Publication number Publication date
JP2002501190A (ja) 2002-01-15
WO1999037996A1 (en) 1999-07-29
AU2829499A (en) 1999-08-09
EP1066507A1 (de) 2001-01-10
DE69902023T2 (de) 2003-02-27
EP1066507B1 (de) 2002-07-03
DE69902023D1 (de) 2002-08-08
DK1066507T3 (da) 2002-10-28
US6493090B1 (en) 2002-12-10

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