DK1066507T3 - Detektering af et stof gennem brydningsindeksændring - Google Patents

Detektering af et stof gennem brydningsindeksændring

Info

Publication number
DK1066507T3
DK1066507T3 DK99908814T DK99908814T DK1066507T3 DK 1066507 T3 DK1066507 T3 DK 1066507T3 DK 99908814 T DK99908814 T DK 99908814T DK 99908814 T DK99908814 T DK 99908814T DK 1066507 T3 DK1066507 T3 DK 1066507T3
Authority
DK
Denmark
Prior art keywords
substance
refractive index
detection
laser
index change
Prior art date
Application number
DK99908814T
Other languages
English (en)
Inventor
Lars Lading
Lars Lindvold
Original Assignee
Torsana Biosensor As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Torsana Biosensor As filed Critical Torsana Biosensor As
Application granted granted Critical
Publication of DK1066507T3 publication Critical patent/DK1066507T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N21/774—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01D—MEASURING NOT SPECIALLY ADAPTED FOR A SPECIFIC VARIABLE; ARRANGEMENTS FOR MEASURING TWO OR MORE VARIABLES NOT COVERED IN A SINGLE OTHER SUBCLASS; TARIFF METERING APPARATUS; MEASURING OR TESTING NOT OTHERWISE PROVIDED FOR
    • G01D5/00—Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable
    • G01D5/26—Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable characterised by optical transfer means, i.e. using infrared, visible, or ultraviolet light
    • G01D5/268—Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable characterised by optical transfer means, i.e. using infrared, visible, or ultraviolet light using optical fibres
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
    • G01N21/45—Refractivity; Phase-affecting properties, e.g. optical path length using interferometric methods; using Schlieren methods
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N21/7746—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the waveguide coupled to a cavity resonator

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Engineering & Computer Science (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Optical Transform (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK99908814T 1998-01-23 1999-01-22 Detektering af et stof gennem brydningsindeksændring DK1066507T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK9198 1998-01-23
PCT/EP1999/000401 WO1999037996A1 (en) 1998-01-23 1999-01-22 Detection of a substance by refractive index change
US09/624,891 US6493090B1 (en) 1998-01-23 2000-07-24 Detection of a substance by refractive index change

Publications (1)

Publication Number Publication Date
DK1066507T3 true DK1066507T3 (da) 2002-10-28

Family

ID=26063288

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99908814T DK1066507T3 (da) 1998-01-23 1999-01-22 Detektering af et stof gennem brydningsindeksændring

Country Status (8)

Country Link
US (1) US6493090B1 (da)
EP (1) EP1066507B1 (da)
JP (1) JP2002501190A (da)
AT (1) ATE220203T1 (da)
AU (1) AU2829499A (da)
DE (1) DE69902023T2 (da)
DK (1) DK1066507T3 (da)
WO (1) WO1999037996A1 (da)

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US7384797B1 (en) 2000-10-12 2008-06-10 University Of Utah Research Foundation Resonant optical cavities for high-sensitivity high-throughput biological sensors and methods
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US6810066B2 (en) * 2002-02-20 2004-10-26 Agilent Technologies, Inc. Fiber-coupled tunable single-mode long-wavelength vertical-cavity laser
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US7149396B2 (en) * 2003-06-16 2006-12-12 The Regents Of The University Of California Apparatus for optical measurements on low-index non-solid materials based on arrow waveguides
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US8178046B2 (en) * 2005-02-23 2012-05-15 Sierra Sensors Gmbh Microfluidic devices with SPR sensing capabilities
DE102005027023A1 (de) * 2005-06-11 2006-12-14 Gerhart Schroff Verfahren und Anordnung zur integralen Dichtheitsprüfung
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US7218802B1 (en) 2005-11-30 2007-05-15 Corning Incorporated Low drift planar waveguide grating sensor and method for manufacturing same
CN101405084B (zh) 2006-03-20 2011-11-16 皇家飞利浦电子股份有限公司 用于电子微流体设备的系统级封装台
US7428055B2 (en) * 2006-10-05 2008-09-23 General Electric Company Interferometer-based real time early fouling detection system and method
US7652767B2 (en) * 2006-10-19 2010-01-26 Sporian Microsystems, Inc. Optical sensor with chemically reactive surface
US7602496B2 (en) * 2006-10-19 2009-10-13 Sporian Microsystems, Inc. Optical sensor with biologically reactive surface
US7746466B2 (en) * 2007-05-14 2010-06-29 The Regents Of The University Of California System and method for flow cytometry
EP2160590A4 (en) * 2007-05-18 2012-11-21 Univ Vanderbilt SYSTEM AND METHOD FOR ENHANCED INTERFEROMETRIC DETECTION
WO2009039466A1 (en) 2007-09-20 2009-03-26 Vanderbilt University Free solution measurement of molecular interactions by backscattering interferometry
WO2009103339A1 (en) * 2008-02-21 2009-08-27 Valtion Teknillinen Tutkimuskeskus Biosensor and a related manufacturing method
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US9518288B2 (en) 2008-04-11 2016-12-13 University Of Utah Research Foundation Methods and compositions related to quantitative, array based methylation analysis
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CN110514233B (zh) * 2019-10-10 2024-04-26 中国计量大学 一种空腔悬浮通道型光纤线上马赫-曾德干涉仪
CN113092385B (zh) * 2021-05-10 2022-03-22 山东大学 中高层大气折射率测量装置及测量方法
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Also Published As

Publication number Publication date
WO1999037996A1 (en) 1999-07-29
DE69902023T2 (de) 2003-02-27
DE69902023D1 (de) 2002-08-08
JP2002501190A (ja) 2002-01-15
EP1066507A1 (en) 2001-01-10
US6493090B1 (en) 2002-12-10
AU2829499A (en) 1999-08-09
EP1066507B1 (en) 2002-07-03
ATE220203T1 (de) 2002-07-15

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