ATE212861T1 - Aminokarboxylat-liganden mit substituierten, aromatischen aminogruppen - Google Patents

Aminokarboxylat-liganden mit substituierten, aromatischen aminogruppen

Info

Publication number
ATE212861T1
ATE212861T1 AT92307091T AT92307091T ATE212861T1 AT E212861 T1 ATE212861 T1 AT E212861T1 AT 92307091 T AT92307091 T AT 92307091T AT 92307091 T AT92307091 T AT 92307091T AT E212861 T1 ATE212861 T1 AT E212861T1
Authority
AT
Austria
Prior art keywords
substituted aromatic
amino
carboxylate ligands
amino groups
aromatic amino
Prior art date
Application number
AT92307091T
Other languages
German (de)
English (en)
Inventor
Radhakrishna Pillai
Edmund R Marinelli
Michael F Tweedle
Ramachandran S Ranganathan
Sang-Ihn Kang
Original Assignee
Bracco Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Int Bv filed Critical Bracco Int Bv
Application granted granted Critical
Publication of ATE212861T1 publication Critical patent/ATE212861T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Hydrogenated Pyridines (AREA)
AT92307091T 1991-08-01 1992-08-03 Aminokarboxylat-liganden mit substituierten, aromatischen aminogruppen ATE212861T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73899891A 1991-08-01 1991-08-01

Publications (1)

Publication Number Publication Date
ATE212861T1 true ATE212861T1 (de) 2002-02-15

Family

ID=24970389

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92307091T ATE212861T1 (de) 1991-08-01 1992-08-03 Aminokarboxylat-liganden mit substituierten, aromatischen aminogruppen

Country Status (17)

Country Link
EP (1) EP0543482B1 (en:Method)
JP (1) JP2538165B2 (en:Method)
KR (1) KR930003911A (en:Method)
CN (1) CN1069027A (en:Method)
AT (1) ATE212861T1 (en:Method)
AU (1) AU2061592A (en:Method)
CA (1) CA2074867A1 (en:Method)
DE (1) DE69232408T2 (en:Method)
ES (1) ES2173862T3 (en:Method)
FI (1) FI923470A7 (en:Method)
HU (1) HUT62906A (en:Method)
IL (1) IL102570A0 (en:Method)
MX (1) MX9204434A (en:Method)
NO (1) NO305126B1 (en:Method)
PL (1) PL295490A1 (en:Method)
TW (1) TW213864B (en:Method)
ZA (1) ZA925521B (en:Method)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5310535A (en) * 1992-04-24 1994-05-10 The Dow Chemical Company Carboxamide modified polyamine chelators and radioactive complexes thereof for conjugation to antibodies
EP0702677A1 (en) * 1994-04-08 1996-03-27 BRACCO International B.V. Aromatic amide compounds and metal chelates thereof
TW319763B (en:Method) 1995-02-01 1997-11-11 Epix Medical Inc
JP4819223B2 (ja) * 1999-02-18 2011-11-24 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 発光マーカーとして使用するためのフタルアミド−ランタニド錯体
FR2802928B1 (fr) * 1999-12-22 2003-01-31 Air Liquide Polyazacycloalcanes eventuellement greffes sur une matrice solide, complexes organometalliques les incorporant comme ligands. utilisation desdits composes a l'extraction de metaux lourds
EP1289571B1 (en) * 2000-05-12 2004-07-21 University Hospital Prochelators of radiometal labeled molecules
FR2827515B1 (fr) * 2001-07-20 2005-06-03 Oreal Composition moussante a base de silice et de polymere cationique
CA2629143A1 (en) * 2005-12-02 2007-06-07 Ge Healthcare As Multimeric magentic resonance contrast agents
RU2425831C2 (ru) * 2005-12-02 2011-08-10 Джи-И Хелткер АС Мультимерные контрастные агенты для магнитного резонанса
IN2014DN03221A (en:Method) * 2011-10-06 2015-05-22 Ihi Corp
CN103073667B (zh) * 2013-01-25 2016-05-11 南京大学 一种双伯胺基螯合树脂及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03203282A (ja) * 1989-12-29 1991-09-04 Nec Kansai Ltd 半導体レーザダイオード
JP2776953B2 (ja) * 1990-04-10 1998-07-16 日本メジフィジックス株式会社 多官能性金属キレート化合物とその用途
DE4035760A1 (de) * 1990-11-08 1992-05-14 Schering Ag Mono-n-substituierte 1,4,7,10-tetraazacyclododecan-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
JP2807852B2 (ja) * 1991-07-18 1998-10-08 株式会社ミドリ十字 新規キレート化剤、該キレート化剤と金属原子との錯化合物及びそれを含む診断剤

Also Published As

Publication number Publication date
FI923470L (fi) 1993-02-02
EP0543482B1 (en) 2002-02-06
PL295490A1 (en) 1993-05-31
FI923470A0 (fi) 1992-07-31
JPH05208920A (ja) 1993-08-20
JP2538165B2 (ja) 1996-09-25
FI923470A7 (fi) 1993-02-02
MX9204434A (es) 1994-06-30
IL102570A0 (en) 1993-01-14
CN1069027A (zh) 1993-02-17
ES2173862T3 (es) 2002-11-01
ZA925521B (en) 1993-04-28
CA2074867A1 (en) 1993-02-02
DE69232408D1 (de) 2002-03-21
DE69232408T2 (de) 2002-09-19
HUT62906A (en) 1993-06-28
KR930003911A (ko) 1993-03-22
TW213864B (en:Method) 1993-10-01
NO923038L (no) 1993-02-02
AU2061592A (en) 1993-02-04
HU9202513D0 (en) 1992-10-28
NO305126B1 (no) 1999-04-06
EP0543482A1 (en) 1993-05-26
NO923038D0 (no) 1992-07-31

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties