ATE203011T1 - Distamycin derivate, verfahren zu ihrer herstellung sowie ihre verwendung als antitumor und antiviral wirkstoffe - Google Patents
Distamycin derivate, verfahren zu ihrer herstellung sowie ihre verwendung als antitumor und antiviral wirkstoffeInfo
- Publication number
- ATE203011T1 ATE203011T1 AT97920753T AT97920753T ATE203011T1 AT E203011 T1 ATE203011 T1 AT E203011T1 AT 97920753 T AT97920753 T AT 97920753T AT 97920753 T AT97920753 T AT 97920753T AT E203011 T1 ATE203011 T1 AT E203011T1
- Authority
- AT
- Austria
- Prior art keywords
- antitumor
- production
- active ingredients
- antiviral active
- distamycin derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9610079.7A GB9610079D0 (en) | 1996-05-14 | 1996-05-14 | Distamycin deriratives process for preparing them and their use as antitumor and antiviral agents |
PCT/EP1997/002158 WO1997043258A1 (en) | 1996-05-14 | 1997-04-24 | Distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE203011T1 true ATE203011T1 (de) | 2001-07-15 |
Family
ID=10793694
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97920753T ATE203011T1 (de) | 1996-05-14 | 1997-04-24 | Distamycin derivate, verfahren zu ihrer herstellung sowie ihre verwendung als antitumor und antiviral wirkstoffe |
Country Status (27)
Country | Link |
---|---|
US (1) | US6177408B1 (de) |
EP (1) | EP0912509B1 (de) |
JP (1) | JP2000510129A (de) |
CN (1) | CN1089755C (de) |
AR (1) | AR007108A1 (de) |
AT (1) | ATE203011T1 (de) |
AU (1) | AU721140B2 (de) |
BR (1) | BR9709451A (de) |
CA (1) | CA2253652A1 (de) |
DE (1) | DE69705622T2 (de) |
DK (1) | DK0912509T3 (de) |
EA (1) | EA002273B1 (de) |
ES (1) | ES2160951T3 (de) |
GB (1) | GB9610079D0 (de) |
GR (1) | GR3036824T3 (de) |
HK (1) | HK1020734A1 (de) |
HU (1) | HUP9901387A3 (de) |
IL (1) | IL126840A (de) |
MY (1) | MY118004A (de) |
NO (1) | NO311886B1 (de) |
NZ (1) | NZ332923A (de) |
PL (1) | PL329878A1 (de) |
PT (1) | PT912509E (de) |
TW (1) | TW498066B (de) |
UA (1) | UA45457C2 (de) |
WO (1) | WO1997043258A1 (de) |
ZA (1) | ZA973883B (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9806692D0 (en) * | 1998-03-27 | 1998-05-27 | Pharmacia & Upjohn Spa | Benzoheterocyclic distamycin derivatives, process for preparing them and their use as antitumour agents |
GB9806689D0 (en) * | 1998-03-27 | 1998-05-27 | Pharmacia & Upjohn Spa | Acryloyl derivatives analogous to distamycin,process for preparing them,and their use as antitumour and antiviral agents |
GB9812211D0 (en) * | 1998-06-05 | 1998-08-05 | Pharmacia & Upjohn Spa | Cinnamoyl distamycin analogous derivatives,process for their preparation,and their use as antitumor agents |
GB9816653D0 (en) * | 1998-07-30 | 1998-09-30 | Pharmacia & Upjohn Spa | Oxidised sulfurated distamycin derivatives process for preparing them and their use as antitumor agents |
GB9816652D0 (en) * | 1998-07-30 | 1998-09-30 | Pharmacia & Upjohn Spa | Sulfurated distamycin derivatives process for preparing them and their use as antitumor agents |
GB9928703D0 (en) * | 1999-12-03 | 2000-02-02 | Pharmacia & Upjohn Spa | Acryloyl peptidic derivatives,process for their preparation and their use as antitumour agents |
US6559125B1 (en) | 2000-01-28 | 2003-05-06 | California Institute Of Technology | Polyamide-alkylator conjugates and related products and method |
GB0011059D0 (en) | 2000-05-08 | 2000-06-28 | Pharmacia & Upjohn Spa | Use of substituted acryloyl distamycin derivatives in the treatment of tumours associated with high levels of glutathione |
GB0015447D0 (en) | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents |
GB0015446D0 (en) | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl distamycin derivates,taxanes and/or antimetabolites |
GB0016447D0 (en) | 2000-07-04 | 2000-08-23 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
GB0017852D0 (en) * | 2000-07-20 | 2000-09-06 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
GB0029004D0 (en) | 2000-11-28 | 2001-01-10 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
EP1470119A4 (de) * | 2001-06-13 | 2005-10-19 | Genesoft Pharmaceuticals Inc | Benzothiophenverbindungen mit antiinfektiver wirkung |
WO2002101007A2 (en) * | 2001-06-13 | 2002-12-19 | Genesoft Pharmaceuticals, Inc | Antipathogenic benzamide compounds |
US6969592B2 (en) | 2001-09-26 | 2005-11-29 | Pharmacia Italia S.P.A. | Method for predicting the sensitivity to chemotherapy |
KR102573190B1 (ko) | 2015-10-16 | 2023-09-01 | 삼성전자주식회사 | 전자장치 및 전자장치 제조방법 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8612218D0 (en) * | 1986-05-20 | 1986-06-25 | Erba Farmitalia | Site specific alkylating agents |
GB9416005D0 (en) * | 1994-08-08 | 1994-09-28 | Erba Carlo Spa | Peptidic compounds analogous to distamycin a and process for their preparation |
-
1996
- 1996-05-14 GB GBGB9610079.7A patent/GB9610079D0/en active Pending
-
1997
- 1997-04-24 AT AT97920753T patent/ATE203011T1/de not_active IP Right Cessation
- 1997-04-24 CN CN97195530A patent/CN1089755C/zh not_active Expired - Fee Related
- 1997-04-24 BR BR9709451A patent/BR9709451A/pt not_active Application Discontinuation
- 1997-04-24 DK DK97920753T patent/DK0912509T3/da active
- 1997-04-24 NZ NZ332923A patent/NZ332923A/xx unknown
- 1997-04-24 EP EP97920753A patent/EP0912509B1/de not_active Expired - Lifetime
- 1997-04-24 WO PCT/EP1997/002158 patent/WO1997043258A1/en active IP Right Grant
- 1997-04-24 PT PT97920753T patent/PT912509E/pt unknown
- 1997-04-24 EA EA199801013A patent/EA002273B1/ru not_active IP Right Cessation
- 1997-04-24 UA UA98126575A patent/UA45457C2/uk unknown
- 1997-04-24 AU AU27016/97A patent/AU721140B2/en not_active Ceased
- 1997-04-24 PL PL97329878A patent/PL329878A1/xx unknown
- 1997-04-24 IL IL12684097A patent/IL126840A/en not_active IP Right Cessation
- 1997-04-24 ES ES97920753T patent/ES2160951T3/es not_active Expired - Lifetime
- 1997-04-24 JP JP09540439A patent/JP2000510129A/ja not_active Withdrawn
- 1997-04-24 CA CA002253652A patent/CA2253652A1/en not_active Abandoned
- 1997-04-24 US US09/147,264 patent/US6177408B1/en not_active Expired - Fee Related
- 1997-04-24 HU HU9901387A patent/HUP9901387A3/hu unknown
- 1997-04-24 DE DE69705622T patent/DE69705622T2/de not_active Expired - Fee Related
- 1997-05-05 TW TW086106038A patent/TW498066B/zh not_active IP Right Cessation
- 1997-05-06 ZA ZA9703883A patent/ZA973883B/xx unknown
- 1997-05-13 MY MYPI97002075A patent/MY118004A/en unknown
- 1997-05-13 AR ARP970101989A patent/AR007108A1/es unknown
-
1998
- 1998-11-13 NO NO19985307A patent/NO311886B1/no unknown
-
1999
- 1999-12-21 HK HK99105996A patent/HK1020734A1/xx not_active IP Right Cessation
-
2001
- 2001-10-08 GR GR20010401685T patent/GR3036824T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2253652A1 (en) | 1997-11-20 |
HUP9901387A3 (en) | 2002-10-28 |
PT912509E (pt) | 2001-12-28 |
JP2000510129A (ja) | 2000-08-08 |
AU2701697A (en) | 1997-12-05 |
EA002273B1 (ru) | 2002-02-28 |
GR3036824T3 (en) | 2002-01-31 |
NO311886B1 (no) | 2002-02-11 |
DK0912509T3 (da) | 2001-10-22 |
HK1020734A1 (en) | 2000-05-19 |
GB9610079D0 (en) | 1996-07-17 |
WO1997043258A1 (en) | 1997-11-20 |
EA199801013A1 (ru) | 1999-06-24 |
CN1089755C (zh) | 2002-08-28 |
DE69705622T2 (de) | 2002-05-08 |
US6177408B1 (en) | 2001-01-23 |
MY118004A (en) | 2004-08-30 |
NO985307D0 (no) | 1998-11-13 |
ES2160951T3 (es) | 2001-11-16 |
AR007108A1 (es) | 1999-10-13 |
UA45457C2 (uk) | 2002-04-15 |
NO985307L (no) | 1999-01-12 |
EP0912509A1 (de) | 1999-05-06 |
IL126840A0 (en) | 1999-09-22 |
EP0912509B1 (de) | 2001-07-11 |
CN1222144A (zh) | 1999-07-07 |
TW498066B (en) | 2002-08-11 |
AU721140B2 (en) | 2000-06-22 |
BR9709451A (pt) | 1999-08-10 |
HUP9901387A2 (hu) | 2000-04-28 |
DE69705622D1 (de) | 2001-08-16 |
IL126840A (en) | 2002-03-10 |
PL329878A1 (en) | 1999-04-12 |
NZ332923A (en) | 2000-03-27 |
ZA973883B (en) | 1997-12-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |