ATE200023T1 - Arzneizubereitung - Google Patents
ArzneizubereitungInfo
- Publication number
- ATE200023T1 ATE200023T1 AT94928043T AT94928043T ATE200023T1 AT E200023 T1 ATE200023 T1 AT E200023T1 AT 94928043 T AT94928043 T AT 94928043T AT 94928043 T AT94928043 T AT 94928043T AT E200023 T1 ATE200023 T1 AT E200023T1
- Authority
- AT
- Austria
- Prior art keywords
- pharmaceutically acceptable
- mixture
- medicinal preparation
- acceptable organic
- solid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13040993A | 1993-10-01 | 1993-10-01 | |
US26727394A | 1994-06-28 | 1994-06-28 | |
US08/297,004 US5559158A (en) | 1993-10-01 | 1994-08-31 | Pharmaceutical composition |
PCT/US1994/010096 WO1995009614A1 (en) | 1993-10-01 | 1994-09-09 | Pharmaceutical composition |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE200023T1 true ATE200023T1 (de) | 2001-04-15 |
Family
ID=27384007
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT94928043T ATE200023T1 (de) | 1993-10-01 | 1994-09-09 | Arzneizubereitung |
Country Status (14)
Country | Link |
---|---|
US (2) | US5559158A (de) |
EP (1) | EP0721330B1 (de) |
JP (1) | JPH09503501A (de) |
KR (1) | KR100330442B1 (de) |
AT (1) | ATE200023T1 (de) |
AU (1) | AU685509B2 (de) |
CA (1) | CA2167413A1 (de) |
DE (1) | DE69426984T2 (de) |
DK (1) | DK0721330T3 (de) |
ES (1) | ES2156904T3 (de) |
GR (1) | GR3036091T3 (de) |
IL (1) | IL110915A (de) |
PT (1) | PT721330E (de) |
WO (1) | WO1995009614A1 (de) |
Families Citing this family (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE143262T1 (de) * | 1992-12-29 | 1996-10-15 | Abbott Lab | Inhibitoren der retroviralen protease |
US5786500A (en) * | 1993-10-22 | 1998-07-28 | Abbott Laboratories | Process for the preparation of a substituted 2.5-diamino-3-hydroxyhexane |
US6037157A (en) | 1995-06-29 | 2000-03-14 | Abbott Laboratories | Method for improving pharmacokinetics |
US5914332A (en) | 1995-12-13 | 1999-06-22 | Abbott Laboratories | Retroviral protease inhibiting compounds |
EP2314598A1 (de) | 1996-10-18 | 2011-04-27 | Vertex Pharmaceuticals Incorporated | Inhibitoren von NS3-Serinprotease aus dem Virus des Hepatitis C |
ZA9710071B (en) * | 1996-11-21 | 1998-05-25 | Abbott Lab | Pharmaceutical composition. |
US6232333B1 (en) | 1996-11-21 | 2001-05-15 | Abbott Laboratories | Pharmaceutical composition |
US6045829A (en) * | 1997-02-13 | 2000-04-04 | Elan Pharma International Limited | Nanocrystalline formulations of human immunodeficiency virus (HIV) protease inhibitors using cellulosic surface stabilizers |
WO1998035666A1 (en) * | 1997-02-13 | 1998-08-20 | Nanosystems Llc | Formulations of nanoparticle naproxen tablets |
WO1998057648A1 (en) * | 1997-06-16 | 1998-12-23 | Vertex Pharmaceuticals Incorporated | Methods of increasing the bioavailability of stable crystal polymorphs of a compound |
MY145265A (en) * | 1998-07-20 | 2012-01-13 | Abbott Lab | Amorphous ritonavir |
US6894171B1 (en) | 1998-07-20 | 2005-05-17 | Abbott Laboratories | Polymorph of a pharmaceutical |
US7141593B1 (en) | 1999-06-04 | 2006-11-28 | Abbott Laboratories | Pharmaceutical formulations |
SI1183026T1 (sl) * | 1999-06-04 | 2006-10-31 | Abbott Lab | Izboljsane farmacevtske spojine, vsebujoce ritonavir |
IT1313624B1 (it) * | 1999-09-21 | 2002-09-09 | Archimica Spa Ora Clariant Lif | Procedimento per la sintesi del ritonavir |
US7364752B1 (en) | 1999-11-12 | 2008-04-29 | Abbott Laboratories | Solid dispersion pharamaceutical formulations |
CA2359945C (en) * | 1999-11-12 | 2011-04-26 | Abbott Laboratories | Inhibitors of crystallization in a solid dispersion |
AU2084801A (en) * | 1999-12-09 | 2001-06-18 | Alza Corporation | Antiviral medication |
SI1248600T1 (sl) | 2000-01-19 | 2008-08-31 | Abbott Lab | Izboljšane farmacevtske formulacije inhibitorjev proteaze HIV |
DE10026698A1 (de) * | 2000-05-30 | 2001-12-06 | Basf Ag | Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung |
SV2003000617A (es) | 2000-08-31 | 2003-01-13 | Lilly Co Eli | Inhibidores de la proteasa peptidomimetica ref. x-14912m |
US6911214B2 (en) | 2000-09-05 | 2005-06-28 | Abbott Laboratories | Flavoring systems for pharmaceutical compositions and methods of making such compositions |
OA12625A (en) * | 2001-06-22 | 2006-06-12 | Pfizer Prod Inc | Pharmaceutical compositions of adsorbates of amorphous drug. |
DE60320940D1 (de) * | 2002-02-01 | 2008-06-26 | Pfizer Prod Inc | Pharmazeutische zusammensetzungen amorpher dispersionen von wirkstoffen und lipophiler mikrophasenbildender materialien |
PT1480679E (pt) * | 2002-02-26 | 2007-07-18 | Astrazeneca Ab | Fórmulação farmacêutica de iressa compreendendo um derivado de celulose solúvel em água |
GB0317663D0 (en) * | 2003-07-29 | 2003-09-03 | Astrazeneca Ab | Pharmaceutical composition |
BRPI0413277A (pt) | 2003-08-04 | 2006-10-10 | Pfizer Prod Inc | composições farmacêuticas de adsorvatos de medicamentos amorfos e materiais que formam microfases lipofìlicas |
US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
PE20050374A1 (es) | 2003-09-05 | 2005-05-30 | Vertex Pharma | Inhibidores de proteasas de serina, en particular proteasa ns3-ns4a del vhc |
US20050071270A1 (en) * | 2003-09-26 | 2005-03-31 | Ramirez Christopher W. | Process for remote recovery and creation of machine specific authentication keys for systems |
NZ546663A (en) | 2003-10-10 | 2010-01-29 | Vertex Pharma | Inhibitors of serine proteases, particularly HCV NS3-NS4A protease |
EP1944042A1 (de) | 2003-10-27 | 2008-07-16 | Vertex Pharmceuticals Incorporated | Kombinationen für die HCV-Behandlung |
AU2004285019B9 (en) | 2003-10-27 | 2011-11-24 | Vertex Pharmaceuticals Incorporated | HCV NS3-NS4A protease resistance mutants |
JP2008505849A (ja) | 2004-02-04 | 2008-02-28 | バーテックス ファーマシューティカルズ インコーポレイテッド | セリンプロテアーゼ、特に、hcv、ns3−ns4aプロテアーゼの阻害剤 |
CN1938004B (zh) * | 2004-03-30 | 2011-12-21 | 欧洲凯尔特公司 | 包含吸附剂和不利剂的抗篡改剂型 |
US8075910B2 (en) | 2004-05-20 | 2011-12-13 | Pbm Pharmaceuticals, Inc. | Oral compositions comprising edible oils and vitamins and/or minerals and methods for making oral compositions |
AU2005291918A1 (en) | 2004-10-01 | 2006-04-13 | Vertex Pharmaceuticals Incorporated | HCV NS3-NS4A protease inhibition |
TWI437990B (zh) | 2004-10-29 | 2014-05-21 | Vertex Pharma | Vx-950之醫藥用途 |
WO2006090264A1 (en) * | 2005-02-28 | 2006-08-31 | Ranbaxy Laboratories Limited | A process for the synthesis of 2-amino-5-protected amino-3-hydroxy-1, 6-diphenylhexane or a salt thereof - an intermediate for antiviral drugs |
DK1912996T3 (da) | 2005-07-29 | 2012-09-17 | Janssen R & D Ireland | Makrocykliske inhibitorer af hepatitis C-virus |
ES2359939T3 (es) | 2005-07-29 | 2011-05-30 | Tibotec Pharmaceuticals | Inhibidores macrocíclicos del virus de la hepatitis c. |
PE20070210A1 (es) | 2005-07-29 | 2007-04-16 | Tibotec Pharm Ltd | Compuestos macrociclicos como inhibidores del virus de hepatitis c |
CN101273027B (zh) | 2005-07-29 | 2015-12-02 | 爱尔兰詹森科学公司 | 丙型肝炎病毒的大环抑制剂 |
JO2768B1 (en) | 2005-07-29 | 2014-03-15 | تيبوتيك فارماسيوتيكالز ليمتد | Large cyclic inhibitors of hepatitis C virus |
AR054882A1 (es) | 2005-07-29 | 2007-07-25 | Tibotec Pharm Ltd | Inhibidores macrociclicos del virus de la hepatitis c |
PE20070211A1 (es) | 2005-07-29 | 2007-05-12 | Medivir Ab | Compuestos macrociclicos como inhibidores del virus de hepatitis c |
RU2436787C2 (ru) | 2005-07-29 | 2011-12-20 | Тиботек Фармасьютикалз Лтд. | Макроциклические ингибиторы вируса гепатита с |
SI1912997T1 (sl) | 2005-07-29 | 2012-02-29 | Tibotec Pharm Ltd | Makrociklični inhibitorji virusa hepatitis C |
WO2007016589A2 (en) | 2005-08-02 | 2007-02-08 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases |
AR055395A1 (es) | 2005-08-26 | 2007-08-22 | Vertex Pharma | Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c |
US7964624B1 (en) | 2005-08-26 | 2011-06-21 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases |
US7705138B2 (en) | 2005-11-11 | 2010-04-27 | Vertex Pharmaceuticals Incorporated | Hepatitis C virus variants |
CA2629343A1 (en) | 2005-11-11 | 2007-05-24 | Vertex Pharmaceuticals, Inc. | Hepatitis c virus variants |
EP2340836A1 (de) | 2006-02-27 | 2011-07-06 | Vertex Pharmceuticals Incorporated | Co-kristalle enthaltend VX-950 und deren pharmazeutische Zusammensetzungen |
BRPI0709567A2 (pt) * | 2006-03-16 | 2011-07-12 | Vertex Pharma | inibidores deuterados de protease de hepatite c |
RU2008143179A (ru) * | 2006-03-31 | 2010-05-10 | Новартис АГ (CH) | Органические соединения |
TW200826932A (en) * | 2006-10-31 | 2008-07-01 | Wyeth Corp | Semi-solid formulations of phospholipase enzyme inhibitors |
JP2010508357A (ja) * | 2006-10-31 | 2010-03-18 | ワイス エルエルシー | ホスホリパーゼ酵素阻害剤の処方 |
US20100113443A1 (en) * | 2006-10-31 | 2010-05-06 | Wyeth | Liquid formulations of phospholipase enzyme inhibitors |
US20080181948A1 (en) * | 2006-11-15 | 2008-07-31 | Abbott Laboratories | Solid pharmaceutical dosage formulations |
WO2008059046A1 (en) | 2006-11-17 | 2008-05-22 | Tibotec Pharmaceuticals Ltd. | Macrocyclic inhibitors of hepatitis c virus |
AU2008212758B2 (en) | 2007-02-08 | 2014-01-30 | Medivir Ab | Pyrimidine substituted macrocyclic HCV inhibitors |
GEP20125645B (en) | 2007-02-27 | 2012-09-25 | Vertex Pharma | Co-crystals and pharmaceutical compositions comprising the same |
AU2008219704A1 (en) | 2007-02-27 | 2008-09-04 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases |
WO2008137126A2 (en) | 2007-05-04 | 2008-11-13 | Vertex Pharmaceuticals Incorporated | Combination therapy for the treatment of hcv infection |
CN101835774B (zh) * | 2007-08-30 | 2014-09-17 | 弗特克斯药品有限公司 | 共晶体和包含该共晶体的药物组合物 |
US10039718B2 (en) * | 2008-05-02 | 2018-08-07 | Gilead Sciences, Inc. | Use of solid carrier particles to improve the processability of a pharmaceutical agent |
KR101016899B1 (ko) | 2008-06-03 | 2011-02-22 | 삼성에스디아이 주식회사 | 배터리 팩 및 그 충전 방법 |
TW201012814A (en) | 2008-07-01 | 2010-04-01 | Centocor Ortho Biotech Products L P | Cyclopropyl polymerase inhibitors |
WO2010070611A1 (en) | 2008-12-18 | 2010-06-24 | Ranbaxy Laboratories Limited | Atazanavir formulations |
JP2012517478A (ja) | 2009-02-12 | 2012-08-02 | バーテックス ファーマシューティカルズ インコーポレイテッド | ペグ化インターフェロン、リバビリンおよびテラプレビルを含む、hcv組合せ治療剤 |
US8945735B2 (en) | 2009-02-23 | 2015-02-03 | Samsung Sdi Co., Ltd. | Built-in charge circuit for secondary battery and secondary battery with the built-in charge circuit |
MX351185B (es) | 2009-04-25 | 2017-10-04 | Hoffmann La Roche | Procedimientos para mejorar la farmocinetica. |
TW201130502A (en) | 2010-01-29 | 2011-09-16 | Vertex Pharma | Therapies for treating hepatitis C virus infection |
CN102917695A (zh) * | 2010-04-09 | 2013-02-06 | 百时美施贵宝公司 | 具有改进的pH效应的阿扎那韦硫酸盐制剂 |
WO2012109646A1 (en) | 2011-02-11 | 2012-08-16 | Vertex Pharmaceuticals Incorporated | Treatment of hcv in hiv infection patients |
WO2012164575A2 (en) | 2011-05-27 | 2012-12-06 | Hetero Research Foundation | Amorphous ritonavir co-precipitated |
UA117375C2 (uk) | 2013-09-04 | 2018-07-25 | Медівір Аб | Інгібітори полімерази hcv |
US20160271160A1 (en) | 2013-10-17 | 2016-09-22 | Medivir Ab | Hcv polymerase inhibitors |
JP6466433B2 (ja) * | 2013-10-24 | 2019-02-06 | ビーブ・ヘルスケア・ユーケイ・(ナンバー5)・リミテッドViiV Healthcare UK (No.5) Limited | ヒト免疫不全ウイルス複製の阻害剤 |
CN106749085B (zh) * | 2016-12-23 | 2019-05-24 | 东北制药集团股份有限公司 | 一种制备利托那韦的方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3903297A (en) * | 1973-11-01 | 1975-09-02 | Upjohn Co | Method of treatment and prophylaxis of gastric hypersecretion and gastric and duodenal ulcers using prostaglandin analogs |
HU9301447D0 (en) * | 1990-11-19 | 1993-11-29 | Monsanto Co | Inhibitors of retrovirus protease |
IE913840A1 (en) * | 1990-11-20 | 1992-05-20 | Abbott Lab | Retroviral protease inhibiting compounds |
CA2056911C (en) * | 1990-12-11 | 1998-09-22 | Yuuichi Nagano | Hiv protease inhibitors |
EP0532466A3 (en) * | 1991-09-12 | 1993-06-16 | Ciba-Geigy Ag | Derivatives of 5-amino-4-hydroxy-hexanoic acid and their therapeutical use |
BR9206623A (pt) * | 1991-10-11 | 1995-05-02 | Du Pont Merck Pharma | Uréias cíclicas e análogas úteis como inibidoras da protease retroviral |
IL103613A (en) * | 1991-11-08 | 1999-05-09 | Merck & Co Inc | VIH protease inhibitors, and the process of preparing intermediates and pharmaceutical preparations containing them. |
US5206219A (en) * | 1991-11-25 | 1993-04-27 | Applied Analytical Industries, Inc. | Oral compositions of proteinaceous medicaments |
IS2334B (is) * | 1992-09-08 | 2008-02-15 | Vertex Pharmaceuticals Inc., (A Massachusetts Corporation) | Aspartyl próteasi hemjari af nýjum flokki súlfonamíða |
ATE143262T1 (de) * | 1992-12-29 | 1996-10-15 | Abbott Lab | Inhibitoren der retroviralen protease |
-
1994
- 1994-08-31 US US08/297,004 patent/US5559158A/en not_active Expired - Lifetime
- 1994-09-09 KR KR1019960700481A patent/KR100330442B1/ko not_active IP Right Cessation
- 1994-09-09 WO PCT/US1994/010096 patent/WO1995009614A1/en active IP Right Grant
- 1994-09-09 AT AT94928043T patent/ATE200023T1/de not_active IP Right Cessation
- 1994-09-09 CA CA002167413A patent/CA2167413A1/en not_active Abandoned
- 1994-09-09 AU AU77229/94A patent/AU685509B2/en not_active Ceased
- 1994-09-09 EP EP94928043A patent/EP0721330B1/de not_active Expired - Lifetime
- 1994-09-09 PT PT94928043T patent/PT721330E/pt unknown
- 1994-09-09 ES ES94928043T patent/ES2156904T3/es not_active Expired - Lifetime
- 1994-09-09 DK DK94928043T patent/DK0721330T3/da active
- 1994-09-09 JP JP7510810A patent/JPH09503501A/ja not_active Ceased
- 1994-09-09 DE DE69426984T patent/DE69426984T2/de not_active Expired - Fee Related
- 1994-09-11 IL IL11091594A patent/IL110915A/xx not_active IP Right Cessation
-
1996
- 1996-05-22 US US08/650,261 patent/US5610193A/en not_active Expired - Fee Related
-
2001
- 2001-06-19 GR GR20010400936T patent/GR3036091T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0721330B1 (de) | 2001-03-28 |
GR3036091T3 (en) | 2001-09-28 |
IL110915A (en) | 1999-12-22 |
DK0721330T3 (da) | 2001-06-25 |
WO1995009614A1 (en) | 1995-04-13 |
US5559158A (en) | 1996-09-24 |
DE69426984T2 (de) | 2001-11-22 |
CA2167413A1 (en) | 1995-04-13 |
AU685509B2 (en) | 1998-01-22 |
JPH09503501A (ja) | 1997-04-08 |
KR100330442B1 (ko) | 2002-08-21 |
US5610193A (en) | 1997-03-11 |
PT721330E (pt) | 2001-09-28 |
IL110915A0 (en) | 1994-11-28 |
EP0721330A1 (de) | 1996-07-17 |
DE69426984D1 (de) | 2001-05-03 |
KR960703567A (ko) | 1996-08-31 |
ES2156904T3 (es) | 2001-08-01 |
AU7722994A (en) | 1995-05-01 |
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UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |