ATE199146T1 - Verfahren zur herstellung von chinolon und naphthyridin carbonsäure als freie basen - Google Patents

Verfahren zur herstellung von chinolon und naphthyridin carbonsäure als freie basen

Info

Publication number
ATE199146T1
ATE199146T1 AT96913229T AT96913229T ATE199146T1 AT E199146 T1 ATE199146 T1 AT E199146T1 AT 96913229 T AT96913229 T AT 96913229T AT 96913229 T AT96913229 T AT 96913229T AT E199146 T1 ATE199146 T1 AT E199146T1
Authority
AT
Austria
Prior art keywords
carboxylic acid
acid salt
naphthyridine
quinolone
naphthyridine carboxylic
Prior art date
Application number
AT96913229T
Other languages
English (en)
Inventor
Gary Jay Dozeman
Kenneth Thomas Porter
James Norton Wemple
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of ATE199146T1 publication Critical patent/ATE199146T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
AT96913229T 1995-05-26 1996-04-26 Verfahren zur herstellung von chinolon und naphthyridin carbonsäure als freie basen ATE199146T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/452,208 US5602254A (en) 1995-05-26 1995-05-26 Method for making quinoline carboxylic acids or naphthyridine carboxylic acids in free base form
PCT/US1996/005899 WO1996037475A1 (en) 1995-05-26 1996-04-26 Method for making quinolone carboxylic acids or naphthyridine carboxylic acids in free base form

Publications (1)

Publication Number Publication Date
ATE199146T1 true ATE199146T1 (de) 2001-02-15

Family

ID=23795530

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96913229T ATE199146T1 (de) 1995-05-26 1996-04-26 Verfahren zur herstellung von chinolon und naphthyridin carbonsäure als freie basen

Country Status (18)

Country Link
US (2) US5602254A (de)
EP (1) EP0828714B1 (de)
JP (1) JPH11505835A (de)
AT (1) ATE199146T1 (de)
CA (1) CA2220080C (de)
CZ (1) CZ289107B6 (de)
DE (1) DE69611782T2 (de)
DK (1) DK0828714T3 (de)
EE (1) EE03522B1 (de)
ES (1) ES2156277T3 (de)
GR (1) GR3035818T3 (de)
HU (1) HUP9901338A3 (de)
MX (1) MX9708562A (de)
NZ (1) NZ307053A (de)
PL (1) PL184063B1 (de)
PT (1) PT828714E (de)
SK (1) SK282666B6 (de)
WO (1) WO1996037475A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19716684B4 (de) * 1997-04-21 2009-11-26 Deep Blue Technology Ag Anker-/Ankerketten-Überwachungsvorrichtung
WO2000054811A1 (fr) 1999-03-17 2000-09-21 Daiichi Pharmaceutical Co., Ltd. Compositions medicamenteuses
JPWO2006004028A1 (ja) * 2004-07-02 2008-04-24 第一製薬株式会社 キノロン含有医薬組成物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53141286A (en) * 1977-05-16 1978-12-08 Kyorin Seiyaku Kk Novel substituted quinolinecarboxylic acid
DE3248507A1 (de) * 1982-12-29 1984-07-05 Bayer Ag, 5090 Leverkusen Mikrobizide mittel auf chinoloncarbonsaeure basis
US4822801A (en) * 1984-07-20 1989-04-18 Warner-Lambert Company 4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivative as antibacterial agents
US4771054A (en) * 1985-01-23 1988-09-13 Warner-Lambert Company Antibacterial agents
DE3713672A1 (de) * 1987-04-24 1988-11-17 Bayer Ag Verfahren zur herstellung von parenteral verabreichbaren chinoloncarbonsaeuren
US4851418A (en) * 1987-08-21 1989-07-25 Warner-Lambert Company Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent
RO101477A2 (ro) * 1988-06-01 1991-11-18 Intreprinderea Textila, Timisoara, Judetul Timis, Ro Procedeu de obtinere a 3,3'-imino-bis-propionamidei
US4950787A (en) * 1988-08-24 1990-08-21 Monsanto Company Chemical process
US4867901A (en) * 1988-08-24 1989-09-19 Bosch Richard J Improved process for reacting salts of D,L-tartaric and maleic acid in the production of ether carboxylate mixtures
US5290794A (en) * 1992-10-27 1994-03-01 Warner Lambert Co. Soluble calcium lactate antibacterial complexes as non-irritating parenteral forms

Also Published As

Publication number Publication date
HUP9901338A2 (hu) 2000-04-28
HUP9901338A3 (en) 2002-10-28
ES2156277T3 (es) 2001-06-16
US5783585A (en) 1998-07-21
SK156497A3 (en) 1998-03-04
JPH11505835A (ja) 1999-05-25
EE9700290A (et) 1998-06-15
CZ366797A3 (cs) 1998-05-13
CZ289107B6 (cs) 2001-11-14
PT828714E (pt) 2001-05-31
GR3035818T3 (en) 2001-07-31
WO1996037475A1 (en) 1996-11-28
NZ307053A (en) 1998-12-23
CA2220080C (en) 2006-11-21
CA2220080A1 (en) 1996-11-28
AU5630996A (en) 1996-12-11
PL184063B1 (pl) 2002-08-30
SK282666B6 (sk) 2002-11-06
MX9708562A (es) 1997-12-31
AU698104B2 (en) 1998-10-22
PL323527A1 (en) 1998-03-30
EP0828714B1 (de) 2001-02-14
EE03522B1 (et) 2001-10-15
DE69611782T2 (de) 2001-06-21
EP0828714A1 (de) 1998-03-18
DE69611782D1 (de) 2001-03-22
DK0828714T3 (da) 2001-03-26
US5602254A (en) 1997-02-11

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee