ATE197952T1 - Neue 1-phenylmethyl-benzimidazol- piperazinderivate - Google Patents
Neue 1-phenylmethyl-benzimidazol- piperazinderivateInfo
- Publication number
- ATE197952T1 ATE197952T1 AT94500089T AT94500089T ATE197952T1 AT E197952 T1 ATE197952 T1 AT E197952T1 AT 94500089 T AT94500089 T AT 94500089T AT 94500089 T AT94500089 T AT 94500089T AT E197952 T1 ATE197952 T1 AT E197952T1
- Authority
- AT
- Austria
- Prior art keywords
- phenylmethyl
- new
- benzimidazole
- piperazine derivatives
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES09301104A ES2072193B1 (es) | 1993-05-21 | 1993-05-21 | Nuevos derivados del1-fenilmetil bencimidazol piperacinas. |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE197952T1 true ATE197952T1 (de) | 2000-12-15 |
Family
ID=8281908
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT94500089T ATE197952T1 (de) | 1993-05-21 | 1994-05-19 | Neue 1-phenylmethyl-benzimidazol- piperazinderivate |
Country Status (5)
Country | Link |
---|---|
US (1) | US5672604A (de) |
EP (1) | EP0628549B1 (de) |
AT (1) | ATE197952T1 (de) |
DE (1) | DE69426372T2 (de) |
ES (1) | ES2072193B1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2731707B1 (fr) * | 1995-03-13 | 1997-04-30 | Synthelabo | Derives de benzimidazole, leur preparation et leur application en therapeutique |
EP0904080A4 (de) * | 1996-04-03 | 2001-08-01 | Merck & Co Inc | Inhibitoren der farnesyl-protein transferase |
US6136807A (en) * | 1998-11-10 | 2000-10-24 | 3M Innovative Properties Company | Composition for the transdermal delivery of lerisetron |
ES2154605B1 (es) * | 1999-09-14 | 2001-11-16 | Univ Madrid Complutense | Nuevos derivados mixtos de bencimidazol-arilpiperazina con afinidad por los receptores serotoninergicos 5-ht1a y 5-ht3 |
US10501421B1 (en) | 2017-01-27 | 2019-12-10 | Vanderbilt University | Substituted benzimidazoles as modulators of Ras signaling |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4941198A (de) * | 1972-09-11 | 1974-04-17 | ||
JPS50126682A (de) * | 1974-03-25 | 1975-10-04 | ||
US4093726A (en) * | 1976-12-02 | 1978-06-06 | Abbott Laboratories | N-(2-benzimidazolyl)-piperazines |
JPS5879983A (ja) * | 1981-11-06 | 1983-05-13 | Kanebo Ltd | 新規なベンズイミダゾ−ル誘導体、その製造法およびその医薬組成物 |
JPH05507702A (ja) * | 1990-05-30 | 1993-11-04 | アメリカン・ホーム・プロダクツ・コーポレイション | 置換アリールスルホンアミド類およびベンズアミド類 |
FR2668150B1 (fr) * | 1990-10-17 | 1994-11-18 | Theramex | Nouveaux derives du terbutylphenyl 1-amino 4-hydroxybutane, leurs procedes de preparation et les compositions pharmaceutiques en renfermant. |
US5248672A (en) * | 1990-11-01 | 1993-09-28 | The Regents Of The University Of Michigan | Polysubstituted benzimidazole nucleosides as antiviral agents |
US5106857A (en) * | 1991-05-09 | 1992-04-21 | A. H. Robins Company, Incorporated | N-(1-methyl-3-pyrrolidinyl)-1-(phenylmethyl)-1H-benzimidazol-2-amine and analogs as antiarrhythmic and muscle relaxing agents |
ES2038532B1 (es) * | 1991-05-10 | 1994-02-16 | Espanola Prod Quimicos | Procedimiento de preparacion de nuevos derivados de 2-piperacinilbecimidazol. |
US5256665A (en) * | 1991-05-10 | 1993-10-26 | Fabrica Espanola De Productos Quimicos Y Farmaceuticos, S.A. | Process for preparing new 2-piperazinylbenzimidazole |
-
1993
- 1993-05-21 ES ES09301104A patent/ES2072193B1/es not_active Expired - Fee Related
-
1994
- 1994-05-19 EP EP94500089A patent/EP0628549B1/de not_active Expired - Lifetime
- 1994-05-19 DE DE69426372T patent/DE69426372T2/de not_active Expired - Fee Related
- 1994-05-19 AT AT94500089T patent/ATE197952T1/de not_active IP Right Cessation
-
1996
- 1996-01-22 US US08/589,651 patent/US5672604A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0628549A1 (de) | 1994-12-14 |
US5672604A (en) | 1997-09-30 |
EP0628549B1 (de) | 2000-12-06 |
DE69426372D1 (de) | 2001-01-11 |
DE69426372T2 (de) | 2001-05-10 |
ES2072193B1 (es) | 1996-02-16 |
ES2072193A1 (es) | 1995-07-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2065895T3 (es) | 2-aminobenzotiazoles sustituidos y derivados de los mismos utiles como agentes cerebrovasculares. | |
FI953968A0 (fi) | Antraniiliset happojohdannaiset | |
ATE140003T1 (de) | 1,8-naphthyridin-2-on-derivate | |
ES2048109B1 (es) | Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol. | |
ATE144511T1 (de) | Tetrahydrobenzimidazol-derivate | |
DE3572170D1 (de) | Quinolonecarboxylic acid derivatives | |
ATE125808T1 (de) | Indolederivate und ihre verwendung als serotonin- antagoniste. | |
DE69122427T2 (de) | Imidazonaphthyridinderivate | |
DE69426372D1 (de) | Neue 1-Phenylmethyl-benzimidazol-piperazinderivate | |
PT97882A (pt) | Processo de preparacao de novos derivados de 2-piperazinilbenzimidazol | |
ATE333447T1 (de) | Cyanoiminochinoxalin-derivate |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |