ATE197952T1 - Neue 1-phenylmethyl-benzimidazol- piperazinderivate - Google Patents

Neue 1-phenylmethyl-benzimidazol- piperazinderivate

Info

Publication number
ATE197952T1
ATE197952T1 AT94500089T AT94500089T ATE197952T1 AT E197952 T1 ATE197952 T1 AT E197952T1 AT 94500089 T AT94500089 T AT 94500089T AT 94500089 T AT94500089 T AT 94500089T AT E197952 T1 ATE197952 T1 AT E197952T1
Authority
AT
Austria
Prior art keywords
phenylmethyl
new
benzimidazole
piperazine derivatives
group
Prior art date
Application number
AT94500089T
Other languages
English (en)
Inventor
Aurelio Orjaves-Venero
Rosa Rodes-Solanes
Original Assignee
Espanola Prod Quimicos
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Espanola Prod Quimicos filed Critical Espanola Prod Quimicos
Application granted granted Critical
Publication of ATE197952T1 publication Critical patent/ATE197952T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT94500089T 1993-05-21 1994-05-19 Neue 1-phenylmethyl-benzimidazol- piperazinderivate ATE197952T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09301104A ES2072193B1 (es) 1993-05-21 1993-05-21 Nuevos derivados del1-fenilmetil bencimidazol piperacinas.

Publications (1)

Publication Number Publication Date
ATE197952T1 true ATE197952T1 (de) 2000-12-15

Family

ID=8281908

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94500089T ATE197952T1 (de) 1993-05-21 1994-05-19 Neue 1-phenylmethyl-benzimidazol- piperazinderivate

Country Status (5)

Country Link
US (1) US5672604A (de)
EP (1) EP0628549B1 (de)
AT (1) ATE197952T1 (de)
DE (1) DE69426372T2 (de)
ES (1) ES2072193B1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2731707B1 (fr) * 1995-03-13 1997-04-30 Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique
WO1997036592A1 (en) * 1996-04-03 1997-10-09 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US6136807A (en) * 1998-11-10 2000-10-24 3M Innovative Properties Company Composition for the transdermal delivery of lerisetron
ES2154605B1 (es) * 1999-09-14 2001-11-16 Univ Madrid Complutense Nuevos derivados mixtos de bencimidazol-arilpiperazina con afinidad por los receptores serotoninergicos 5-ht1a y 5-ht3
US10501421B1 (en) 2017-01-27 2019-12-10 Vanderbilt University Substituted benzimidazoles as modulators of Ras signaling

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4941198A (de) * 1972-09-11 1974-04-17
JPS50126682A (de) * 1974-03-25 1975-10-04
US4093726A (en) * 1976-12-02 1978-06-06 Abbott Laboratories N-(2-benzimidazolyl)-piperazines
JPS5879983A (ja) * 1981-11-06 1983-05-13 Kanebo Ltd 新規なベンズイミダゾ−ル誘導体、その製造法およびその医薬組成物
JPH05507702A (ja) * 1990-05-30 1993-11-04 アメリカン・ホーム・プロダクツ・コーポレイション 置換アリールスルホンアミド類およびベンズアミド類
FR2668150B1 (fr) * 1990-10-17 1994-11-18 Theramex Nouveaux derives du terbutylphenyl 1-amino 4-hydroxybutane, leurs procedes de preparation et les compositions pharmaceutiques en renfermant.
US5248672A (en) * 1990-11-01 1993-09-28 The Regents Of The University Of Michigan Polysubstituted benzimidazole nucleosides as antiviral agents
US5106857A (en) * 1991-05-09 1992-04-21 A. H. Robins Company, Incorporated N-(1-methyl-3-pyrrolidinyl)-1-(phenylmethyl)-1H-benzimidazol-2-amine and analogs as antiarrhythmic and muscle relaxing agents
US5256665A (en) * 1991-05-10 1993-10-26 Fabrica Espanola De Productos Quimicos Y Farmaceuticos, S.A. Process for preparing new 2-piperazinylbenzimidazole
ES2038532B1 (es) * 1991-05-10 1994-02-16 Espanola Prod Quimicos Procedimiento de preparacion de nuevos derivados de 2-piperacinilbecimidazol.

Also Published As

Publication number Publication date
US5672604A (en) 1997-09-30
DE69426372D1 (de) 2001-01-11
EP0628549B1 (de) 2000-12-06
ES2072193A1 (es) 1995-07-01
EP0628549A1 (de) 1994-12-14
ES2072193B1 (es) 1996-02-16
DE69426372T2 (de) 2001-05-10

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties