ATE196252T1 - Behandlung von hornincontinenz durch verwendung von (s)-oxybutynin und (s)-desethyloxybutynin - Google Patents

Behandlung von hornincontinenz durch verwendung von (s)-oxybutynin und (s)-desethyloxybutynin

Info

Publication number
ATE196252T1
ATE196252T1 AT96906202T AT96906202T ATE196252T1 AT E196252 T1 ATE196252 T1 AT E196252T1 AT 96906202 T AT96906202 T AT 96906202T AT 96906202 T AT96906202 T AT 96906202T AT E196252 T1 ATE196252 T1 AT E196252T1
Authority
AT
Austria
Prior art keywords
desethyloxybutynin
oxybutynin
incontinence
horn
treatment
Prior art date
Application number
AT96906202T
Other languages
German (de)
English (en)
Inventor
Gunnar Aberg
Cullough John R Mc
Yue Fang
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/381,542 external-priority patent/US5532278A/en
Application filed by Sepracor Inc filed Critical Sepracor Inc
Application granted granted Critical
Publication of ATE196252T1 publication Critical patent/ATE196252T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT96906202T 1995-01-31 1996-01-25 Behandlung von hornincontinenz durch verwendung von (s)-oxybutynin und (s)-desethyloxybutynin ATE196252T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/381,542 US5532278A (en) 1995-01-31 1995-01-31 Methods and compositions for treating urinary incontinence using optically pure (S)-oxybutynin
US08/480,194 US5677346A (en) 1995-01-31 1995-06-07 Treating urinary incontinence using (S)-desethyloxybutynin
PCT/US1996/001053 WO1996023492A1 (en) 1995-01-31 1996-01-25 Treating urinary incontinence using (s)-oxybutynin and (s)-desethyloxybutynin

Publications (1)

Publication Number Publication Date
ATE196252T1 true ATE196252T1 (de) 2000-09-15

Family

ID=27009434

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96906202T ATE196252T1 (de) 1995-01-31 1996-01-25 Behandlung von hornincontinenz durch verwendung von (s)-oxybutynin und (s)-desethyloxybutynin

Country Status (24)

Country Link
US (1) US5677346A (cs)
EP (1) EP0806948B1 (cs)
JP (1) JPH11511730A (cs)
KR (1) KR100390271B1 (cs)
CN (1) CN1151786C (cs)
AT (1) ATE196252T1 (cs)
AU (1) AU706741B2 (cs)
BR (1) BR9607001A (cs)
CA (1) CA2211400C (cs)
CZ (1) CZ290093B6 (cs)
DE (1) DE69610290T2 (cs)
DK (1) DK0806948T3 (cs)
ES (1) ES2150663T3 (cs)
FI (1) FI973163L (cs)
GR (1) GR3034974T3 (cs)
HU (1) HUP9800794A3 (cs)
NO (1) NO315927B1 (cs)
NZ (1) NZ303372A (cs)
PL (1) PL182768B1 (cs)
PT (1) PT806948E (cs)
RU (1) RU2181589C2 (cs)
SK (1) SK283313B6 (cs)
UA (1) UA45387C2 (cs)
WO (1) WO1996023492A1 (cs)

Families Citing this family (49)

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US5736577A (en) * 1995-01-31 1998-04-07 Sepracor, Inc. Methods and compositions for treating urinary incontinence using optically pure (S)-oxybutynin
US6171298B1 (en) 1996-05-03 2001-01-09 Situs Corporation Intravesical infuser
WO1998011888A1 (en) * 1996-09-19 1998-03-26 American Home Products Corporation Method of treating urinary incontinence
US6123961A (en) * 1996-09-25 2000-09-26 Bridge Pharma, Inc. Treating urinary incontinence with (R)-desethyloxybutynin and (R)-oxybutynin
EP1041981A2 (en) * 1997-12-31 2000-10-11 Sepracor, Inc. $i(S)-PROCYCLIDINE FOR TREATING URINARY INCONTINENCE
US6183461B1 (en) 1998-03-11 2001-02-06 Situs Corporation Method for delivering a medication
US6013830A (en) * 1998-03-30 2000-01-11 Sepracor Inc. Asymmetric grignard synthesis with cyclic 1,2 aminoalcohols
ME00850B (me) * 1998-08-27 2008-08-07 Pfizer Health Ab Nove perle sa kontrolisanim oslobađanjem, postupak za njihovu proizvodnju i višestruka jedinična formulacija koja ih sadrži
WO2000071108A2 (en) 1999-05-20 2000-11-30 Sepracor Inc. Methods for treatment of asthma using s-oxybutynin
US6432446B2 (en) * 2000-02-03 2002-08-13 Bridge Pharma, Inc. Non-arrhythmogenic metabolite of oxybutynin
US6521724B2 (en) 2000-03-10 2003-02-18 E. I. Du Pont De Nemours And Company Polymerization process
US6436428B1 (en) 2000-03-21 2002-08-20 Enhance Pharmaceuticals, Inc. Device and method for treating urinary incontinence in females
US7029694B2 (en) 2000-04-26 2006-04-18 Watson Laboratories, Inc. Compositions and methods for transdermal oxybutynin therapy
BR0110381A (pt) 2000-04-26 2003-12-30 Watson Pharmaceuticals Inc Minimizando experiência adversa associada com terapia com oxibutinina
US7179483B2 (en) * 2000-04-26 2007-02-20 Watson Pharmaceuticals, Inc. Compositions and methods for transdermal oxybutynin therapy
US20030124177A1 (en) * 2000-04-26 2003-07-03 Watson Pharmaceuticals, Inc. Compositions and methods for transdermal oxybutynin therapy
AU2000255966B2 (en) * 2000-06-07 2005-03-24 Allergan Sales, Llc Treating smooth muscle hyperactivity with (r)-oxybutynin and (r)- desethyloxybutynin
ES2283425T3 (es) * 2000-08-03 2007-11-01 Antares Pharma Ipl Ag Nueva composicion para la administracion transdermica y/o transmucosa de compuestos activos que asegura niveles terapeutiocos adecuados.
US7198801B2 (en) 2000-08-03 2007-04-03 Antares Pharma Ipl Ag Formulations for transdermal or transmucosal application
WO2005039531A1 (en) 2003-10-10 2005-05-06 Antares Pharma Ipl Ag Transdermal pharmaceutical formulation for minimizing skin residues
US8980290B2 (en) 2000-08-03 2015-03-17 Antares Pharma Ipl Ag Transdermal compositions for anticholinergic agents
DE10041478A1 (de) 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
DE10060550C1 (de) * 2000-12-06 2002-04-18 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit dem Wirkstoff Oxybutynin und Verfahren zur Herstellung Oxybutynin enthaltender Wirkstoffschichten
DE10103262A1 (de) * 2001-01-25 2002-08-01 Axel Schmidt-Dossi Arzneimittel gegen Blasenfunktionsstörung
DE60234318D1 (de) * 2001-02-08 2009-12-24 Ono Pharmaceutical Co Mittel zur behandlung von harnwegserkrankungen, umfassend mittel zur kontrolle des lpa-rezeptors
CN1536986B (zh) * 2001-03-27 2012-07-04 沃纳奇尔科特(爱尔兰)有限公司 用于抗微生物剂给药的阴道内药物递送装置
US20030027856A1 (en) * 2001-06-29 2003-02-06 Aberg A.K. Gunnar Tolterodine metabolites
BR0206300A (pt) * 2001-11-05 2008-04-08 Upjohn Co composição farmacêutica para tratar distúrbio urinário em um mamìfero e uso
US20030185882A1 (en) * 2001-11-06 2003-10-02 Vergez Juan A. Pharmaceutical compositions containing oxybutynin
US7921999B1 (en) * 2001-12-20 2011-04-12 Watson Laboratories, Inc. Peelable pouch for transdermal patch and method for packaging
JP2005516992A (ja) * 2001-12-21 2005-06-09 ブリッジ ファーマ、インコーポレイテッド オキシブチニンの非心律動異常惹起性代謝物
DK1426049T3 (da) * 2002-12-02 2005-08-22 Sanol Arznei Schwarz Gmbh Iontophoretisk tilförsel af rotigotin til behandling af Parkinsons sygdom
RU2241442C1 (ru) * 2003-09-17 2004-12-10 Научный центр акушерства, гинекологии и перинатологии РАМН Вагинальные суппозитории для лечения императивного недержания мочеиспускания
US7425340B2 (en) * 2004-05-07 2008-09-16 Antares Pharma Ipl Ag Permeation enhancing compositions for anticholinergic agents
WO2007124250A2 (en) 2006-04-21 2007-11-01 Antares Pharma Ipl Ag Methods of treating hot flashes with formulations for transdermal or transmucosal application
WO2006125642A1 (en) 2005-05-27 2006-11-30 Antares Pharma Ipl Ag Methods and apparatus for transdermal or transmucosal application of testosterone
US8415390B2 (en) 2008-05-30 2013-04-09 Microdose Therapeutx, Inc. Methods and compositions for administration of oxybutynin
BRPI0812000A2 (pt) * 2007-05-30 2014-11-18 Microdose Therapeutx Inc Métodos e composições para administração de oxibutinina
US9119777B2 (en) 2008-05-30 2015-09-01 Microdose Therapeutx, Inc. Methods and compositions for administration of oxybutynin
US8920392B2 (en) 2009-05-05 2014-12-30 Watson Laboratories, Inc. Method for treating overactive bladders and a device for storage and administration of topical oxybutynin compositions
US9907767B2 (en) 2010-08-03 2018-03-06 Velicept Therapeutics, Inc. Pharmaceutical compositions and the treatment of overactive bladder
PH12013500221A1 (en) 2010-08-03 2017-08-23 Altherx Inc Combinations of beta - 3 adrenergic receptor agonists and muscarinic receptor antagonists for treating overactive bladder
AR089957A1 (es) 2012-02-09 2014-10-01 Altherx Inc Combinaciones farmaceuticas, combinaciones sinergicas
JP2012176958A (ja) * 2012-04-20 2012-09-13 Watson Pharmaceuticals Inc （ｒ）−オキシブチニンおよび（ｒ）−デスエチルオキシブチニンによる平滑筋機能亢進の処置
US20160151321A1 (en) 2012-11-13 2016-06-02 Dinesh C. Patel Methods for the treatment of sialorrhea
US20140135392A1 (en) * 2012-11-13 2014-05-15 NeuRx Pharmaceuticals LLC Methods for the treatment of sialorrhea
CN104116760A (zh) * 2014-07-14 2014-10-29 玉庆花 一种治疗遗尿的口服液
CN107205964A (zh) 2014-12-03 2017-09-26 威力塞帕特治疗股份有限公司 使用调节释放索拉贝隆用于下尿路症状的组合物和方法
EP3365321B1 (en) 2015-10-23 2023-12-13 B3AR Therapeutics, Inc. Solabegron zwitterion and uses thereof

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* Cited by examiner, † Cited by third party
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NL267508A (cs) * 1960-07-26
BE902605A (fr) * 1985-06-06 1985-09-30 Therabel Res S A N V Composition pharmaceutique utilisable dans le traitement des maladies des voies urinaires, son procede de preparation et methode d'utilisation de cette composition.
MX9202350A (es) * 1991-05-20 1992-11-01 Alza Corp Composiciones de incrementador de penetracion a la piel que usan monolinoleato de glicerol.
JP3066515B2 (ja) * 1992-11-11 2000-07-17 久光製薬株式会社 尿失禁治療用経皮投与製剤
US5750137A (en) * 1993-09-29 1998-05-12 Taskovich; Lina Tormen Monoglyceride/lactate ester permeation enhancer

Also Published As

Publication number Publication date
MX9705820A (es) 1997-10-31
US5677346A (en) 1997-10-14
WO1996023492A1 (en) 1996-08-08
DE69610290T2 (de) 2001-03-29
BR9607001A (pt) 1997-10-28
SK103597A3 (en) 1999-03-12
ES2150663T3 (es) 2000-12-01
GR3034974T3 (en) 2001-02-28
HUP9800794A3 (en) 1999-05-28
AU706741B2 (en) 1999-06-24
FI973163A7 (fi) 1997-09-30
RU2181589C2 (ru) 2002-04-27
CA2211400C (en) 2007-01-23
HK1017986A1 (en) 1999-12-10
NZ303372A (en) 1999-01-28
HUP9800794A2 (hu) 1998-07-28
DK0806948T3 (da) 2000-12-18
PL321498A1 (en) 1997-12-08
FI973163A0 (fi) 1997-07-30
SK283313B6 (sk) 2003-05-02
EP0806948B1 (en) 2000-09-13
NO973516D0 (no) 1997-07-30
PT806948E (pt) 2001-02-28
CZ290093B6 (cs) 2002-05-15
PL182768B1 (pl) 2002-02-28
AU4966496A (en) 1996-08-21
CN1151786C (zh) 2004-06-02
NO315927B1 (no) 2003-11-17
CZ242197A3 (en) 1997-12-17
NO973516L (no) 1997-08-07
DE69610290D1 (de) 2000-10-19
FI973163L (fi) 1997-09-30
CA2211400A1 (en) 1996-08-08
EP0806948A1 (en) 1997-11-19
UA45387C2 (uk) 2002-04-15
KR100390271B1 (ko) 2003-10-04
CN1179714A (zh) 1998-04-22
JPH11511730A (ja) 1999-10-12

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