ATE194607T1 - Amorph piretanide, polymorphe davon, verfahren zur dessen herstellung und ihre verwendung - Google Patents
Amorph piretanide, polymorphe davon, verfahren zur dessen herstellung und ihre verwendungInfo
- Publication number
- ATE194607T1 ATE194607T1 AT96904993T AT96904993T ATE194607T1 AT E194607 T1 ATE194607 T1 AT E194607T1 AT 96904993 T AT96904993 T AT 96904993T AT 96904993 T AT96904993 T AT 96904993T AT E194607 T1 ATE194607 T1 AT E194607T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- sec
- peak
- piretanide
- date
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- UJEWTUDSLQGTOA-UHFFFAOYSA-N Piretanide Chemical compound C=1C=CC=CC=1OC=1C(S(=O)(=O)N)=CC(C(O)=O)=CC=1N1CCCC1 UJEWTUDSLQGTOA-UHFFFAOYSA-N 0.000 abstract 2
- 229960001085 piretanide Drugs 0.000 abstract 2
- 230000009102 absorption Effects 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 238000000862 absorption spectrum Methods 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 238000000634 powder X-ray diffraction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Epoxy Compounds (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Glass Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP03321595A JP3532987B2 (ja) | 1995-02-22 | 1995-02-22 | 新規な無晶形ピレタニドおよびその製造方法 |
| JP03321695A JP3532988B2 (ja) | 1995-02-22 | 1995-02-22 | ピレタニドの新規な結晶多形およびその製造方法 |
| PCT/IB1996/000254 WO1996026197A1 (en) | 1995-02-22 | 1996-02-12 | Amorphous piretanide, piretanide polymorphs, process for their preparation and their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE194607T1 true ATE194607T1 (de) | 2000-07-15 |
Family
ID=26371876
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96904993T ATE194607T1 (de) | 1995-02-22 | 1996-02-12 | Amorph piretanide, polymorphe davon, verfahren zur dessen herstellung und ihre verwendung |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6096779A (de) |
| EP (1) | EP0812320B1 (de) |
| KR (1) | KR100419355B1 (de) |
| CN (1) | CN1072215C (de) |
| AT (1) | ATE194607T1 (de) |
| BR (1) | BR9607295A (de) |
| CA (1) | CA2213693C (de) |
| DE (1) | DE69609314T2 (de) |
| DK (1) | DK0812320T3 (de) |
| ES (1) | ES2150105T3 (de) |
| GR (1) | GR3034605T3 (de) |
| MX (1) | MX9706339A (de) |
| PT (1) | PT812320E (de) |
| WO (1) | WO1996026197A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW403740B (en) | 1997-06-10 | 2000-09-01 | Novartis Ag | Novel crystal modifications of the compound 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide |
| DE10013289A1 (de) * | 2000-03-17 | 2001-09-20 | Knoll Ag | Torasemid enthaltende pharmazeutische Zubereitungen |
| HRP20000162B1 (en) * | 2000-03-20 | 2004-06-30 | Pliva D D | Amorphous torasemide modification |
| AU2003271740B2 (en) * | 2002-05-16 | 2010-05-13 | Janssen R&D Ireland | Pseudopolymorphic forms of a HIV protease inhibitor |
| EP1734931A2 (de) * | 2004-03-24 | 2006-12-27 | Actavis Group | Formulierungen von ramipril |
| GB2431579A (en) * | 2005-10-28 | 2007-05-02 | Arrow Int Ltd | Ramipril formulations |
| US20070098782A1 (en) * | 2005-10-28 | 2007-05-03 | Selamine Limited | Ramipril Formulation |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2419970C3 (de) * | 1974-04-25 | 1980-06-12 | Hoechst Ag, 6000 Frankfurt | 3-<l-Pyrrolidinyl)-4-phenoxy-5sulfamoylbenzoesäure und Verfahren zu ihrer Herstellung |
| JPS5283547A (en) * | 1976-01-01 | 1977-07-12 | Hoechst Ag | Tertiary cyclic amine |
| DE2655331A1 (de) * | 1976-12-07 | 1978-06-08 | Hoechst Ag | Zubereitungsformen von 3-n-pyrrolidino-4-phenoxy-5-sulfamyl-benzoesaeure und verfahren zu ihrer herstellung |
| ATE66157T1 (de) * | 1986-04-29 | 1991-08-15 | Hoechst Roussel Pharma | Schichtenstruktur fuer die verabreichung von chemikalien mit kontrollierter abgaberate. |
| EP0465841A3 (en) * | 1990-06-13 | 1992-10-14 | Hoechst Aktiengesellschaft | Quick acting pharmaceutical inhalation forms of diuretics |
| JPH05230044A (ja) * | 1992-02-21 | 1993-09-07 | Hoechst Japan Ltd | ピレタニドの新規な結晶多形 |
-
1996
- 1996-02-12 EP EP96904993A patent/EP0812320B1/de not_active Expired - Lifetime
- 1996-02-12 CN CN96192081A patent/CN1072215C/zh not_active Expired - Lifetime
- 1996-02-12 PT PT96904993T patent/PT812320E/pt unknown
- 1996-02-12 ES ES96904993T patent/ES2150105T3/es not_active Expired - Lifetime
- 1996-02-12 KR KR1019970705772A patent/KR100419355B1/ko not_active Expired - Lifetime
- 1996-02-12 WO PCT/IB1996/000254 patent/WO1996026197A1/en not_active Ceased
- 1996-02-12 US US08/894,412 patent/US6096779A/en not_active Expired - Lifetime
- 1996-02-12 DE DE69609314T patent/DE69609314T2/de not_active Expired - Lifetime
- 1996-02-12 CA CA002213693A patent/CA2213693C/en not_active Expired - Lifetime
- 1996-02-12 DK DK96904993T patent/DK0812320T3/da active
- 1996-02-12 BR BR9607295A patent/BR9607295A/pt not_active IP Right Cessation
- 1996-02-12 AT AT96904993T patent/ATE194607T1/de active
-
1997
- 1997-08-20 MX MX9706339A patent/MX9706339A/es unknown
-
2000
- 2000-10-12 GR GR20000402289T patent/GR3034605T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1996026197A1 (en) | 1996-08-29 |
| DK0812320T3 (da) | 2003-04-14 |
| EP0812320B1 (de) | 2000-07-12 |
| DE69609314T2 (de) | 2001-06-13 |
| KR100419355B1 (ko) | 2004-06-04 |
| MX9706339A (es) | 1998-07-31 |
| KR19980702374A (ko) | 1998-07-15 |
| CA2213693A1 (en) | 1996-08-29 |
| ES2150105T3 (es) | 2000-11-16 |
| DE69609314D1 (de) | 2000-08-17 |
| BR9607295A (pt) | 1997-11-25 |
| HK1006783A1 (en) | 1999-03-19 |
| GR3034605T3 (en) | 2001-01-31 |
| US6096779A (en) | 2000-08-01 |
| CA2213693C (en) | 2008-04-15 |
| EP0812320A1 (de) | 1997-12-17 |
| CN1072215C (zh) | 2001-10-03 |
| PT812320E (pt) | 2000-12-29 |
| CN1175948A (zh) | 1998-03-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEIH | Change in the person of patent owner | ||
| UEP | Publication of translation of european patent specification |
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