ATE13669T1 - 4-aryloxy-3-phenylpiperidin-derivate, zwischenprodukte, verfahren zur herstellung solcher verbindungen und ihre verwendung als arzneimittel. - Google Patents

4-aryloxy-3-phenylpiperidin-derivate, zwischenprodukte, verfahren zur herstellung solcher verbindungen und ihre verwendung als arzneimittel.

Info

Publication number
ATE13669T1
ATE13669T1 AT80104877T AT80104877T ATE13669T1 AT E13669 T1 ATE13669 T1 AT E13669T1 AT 80104877 T AT80104877 T AT 80104877T AT 80104877 T AT80104877 T AT 80104877T AT E13669 T1 ATE13669 T1 AT E13669T1
Authority
AT
Austria
Prior art keywords
compounds
aryloxy
preparation
products
processes
Prior art date
Application number
AT80104877T
Other languages
English (en)
Inventor
Solomon Samuel Klioze
Frederick Jacob Ehrgott
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Application granted granted Critical
Publication of ATE13669T1 publication Critical patent/ATE13669T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/54—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT80104877T 1980-02-19 1980-08-16 4-aryloxy-3-phenylpiperidin-derivate, zwischenprodukte, verfahren zur herstellung solcher verbindungen und ihre verwendung als arzneimittel. ATE13669T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/117,532 US4312876A (en) 1979-02-23 1980-02-19 Antidepressive and analgesic 4-aryloxy- and 4-arylthio-3-phenylpiperidines
EP80104877A EP0034647B1 (de) 1980-02-19 1980-08-16 4-Aryloxy-3-phenylpiperidin-Derivate, Zwischenprodukte, Verfahren zur Herstellung solcher Verbindungen und ihre Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
ATE13669T1 true ATE13669T1 (de) 1985-06-15

Family

ID=22373434

Family Applications (1)

Application Number Title Priority Date Filing Date
AT80104877T ATE13669T1 (de) 1980-02-19 1980-08-16 4-aryloxy-3-phenylpiperidin-derivate, zwischenprodukte, verfahren zur herstellung solcher verbindungen und ihre verwendung als arzneimittel.

Country Status (7)

Country Link
US (1) US4312876A (de)
EP (1) EP0034647B1 (de)
JP (1) JPS56118062A (de)
AT (1) ATE13669T1 (de)
CA (1) CA1160231A (de)
DE (1) DE3070735D1 (de)
ES (1) ES493888A0 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4387229A (en) * 1977-09-13 1983-06-07 Pfizer Inc. 3-[2-Hydroxy-4-(substituted)phenyl]azacycloalkanols and derivatives thereof
US4496732A (en) * 1983-03-14 1985-01-29 Hoechst-Roussel Pharmaceuticals Inc. Stereoselective reduction of 2- or 3-substituted 4-piperidones with sodium borohydride
GB8321157D0 (en) * 1983-08-05 1983-09-07 Fordonal Sa Piperidine derivatives
ZA9610741B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
EP1748984A1 (de) * 2004-05-12 2007-02-07 Pfizer Products Inc. Piperidinderivate als nk1- und nk3-antagonisten
US20070099237A1 (en) * 2005-10-31 2007-05-03 The Regents Of The University Of Michigan Reaction co-crystallization of molecular complexes or co-crystals

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3260723A (en) * 1963-08-27 1966-07-12 Parke Davis & Co 4-phenoxy piperidines; alpha4-phenoxy piperideines
US3542794A (en) * 1969-11-07 1970-11-24 Grover Cleveland Helsley 1-carbamoyl-4-phenoxypiperidines
DE2116316A1 (de) * 1970-04-08 1971-10-28 Sandoz Ag, Basel (Schweiz) Verfahren zur Herstellung neuer heterocyclischer Verbindungen
US3743645A (en) * 1970-10-19 1973-07-03 Robins Co Inc A H 1-substituted-4-phenoxypiperidines
US4132709A (en) * 1976-12-20 1979-01-02 Ayerst, Mckenna & Harrison, Ltd. [2]Benzopyrano[4,3-c]pyridine derivatives and process therefor
US4147872A (en) * 1977-09-13 1979-04-03 Pfizer Inc. 3-[2-Hydroxy-4-(substituted)-phenyl]azacycloalkanes and derivatives thereof as analgesic agents and intermediates therefor
US4216218A (en) * 1979-02-23 1980-08-05 American Hoechst Corporation Antidepressant and analgesic 4-aryloxy- and 4-arylthio-3-phenylpiperidines

Also Published As

Publication number Publication date
US4312876A (en) 1982-01-26
EP0034647A2 (de) 1981-09-02
JPS56118062A (en) 1981-09-16
JPH0243741B2 (de) 1990-10-01
ES8105711A1 (es) 1981-06-16
DE3070735D1 (en) 1985-07-11
EP0034647B1 (de) 1985-06-05
ES493888A0 (es) 1981-06-16
EP0034647A3 (en) 1982-03-03
CA1160231A (en) 1984-01-10

Similar Documents

Publication Publication Date Title
DE58907280D1 (de) 7-Substituierte Derivate der 3,5-Dihydroxyhept-6-insäure, Verfahren zu ihrer Herstellung, ihre Verwendung als Arzneimittel, sowie Zwischenprodukte.
ATE62683T1 (de) Labdanderivate, verfahren zu deren herstellung und deren verwendung als arzneimittel.
ATE120732T1 (de) Pyrrolidin- und thiazolidinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
ATE151764T1 (de) Neue benzopyran-derivate, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltenden zubereitungen
DE3775882D1 (de) Substituierte 6-fluor-4-oxo-1,4-dihydrochinolin-3-carbonsaeuren ; deren derivate; diese verbindung enthaltende pharmazeutische zubereitungen und verfahren zur herstellung dieser verbindungen.
ATE1192T1 (de) Verfahren zur herstellung von beta-lactam-derivaten, die so erhaltenen neuen derivate sowie diese derivate enthaltende pharmazeutische zusammensetzungen.
DE3581566D1 (de) Oxindol-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und zwischenprodukte.
ATE104271T1 (de) 2-(2-hydroxy-3phenoxypropylamino)ethylphenoxyacetamide, verfahren und zwischenprodukte zu deren herstellung.
LU78804A1 (de) N-substituierte w-aminoalkanoyl-w-aminoalkansaeuren,ihre verwendung und verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
NO933200L (no) Substituerte cykloheksanderivater, fremgangsmåte til fremstilling derav og anvendelsen av forbindelsene til behandling av sykdommer
ATE4642T1 (de) 2-hydroxyalkyl-3,4,5-trihydroxypiperidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
ATE4203T1 (de) 4-aryloxy- und 4-arylthio-3-phenylpiperidinderivate, verfahren zur herstellung solcher verbindungen und diese enthaltende pharmazeutische zusammensetzungen.
ATE13669T1 (de) 4-aryloxy-3-phenylpiperidin-derivate, zwischenprodukte, verfahren zur herstellung solcher verbindungen und ihre verwendung als arzneimittel.
ATE139777T1 (de) 20-21-dinoreburnamenin-derivate, verfahren zu ihrer herstellung und zwischenverbindungen, ihre anwendung als arzneimittel und diese enthaltende zusammenstellungen
ATE4117T1 (de) Pseudotrisaccharide, ihre herstellung und verwendung als arzneimittel.
ATE124039T1 (de) Durch azetidine substituierte derivate von pyridon-carboxylsäure, ihre herstellung und verwendung als arzneimittel.
ATE81499T1 (de) 2-acyloxypropylamin-derivate, verfahren zur herstellung und diese enthaltende arzneimittel.
ATE9330T1 (de) Phenethanolamin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
ATE181832T1 (de) Pyrido-pyrimidindione, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3678478D1 (de) Beta-lactam-antibiotika, verfahren zur herstellung und ihre verwendung als arzneimittel.
DE3886950D1 (de) Platin-verbindungen, geeignet zur verwendung als arzneimittel.
ATE8621T1 (de) 6-keto-pge1- und pgi1-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
PT70560A (de) 1,3,4-thiadiazol-2-carbonsaure-derivate verfahren zur herstellung dieser verbindungen sowie diese enthaltende fungizide und nematizide mittel
ATE100102T1 (de) Substituierte derivate von 20,21dinoreburnamenin, verfahren zur herstellung und so hergestellte zwischenprodukte, ihre verwendung als arzneimittel und diese enthaltende pharmazeutische zusammenstellungen.
ATE119149T1 (de) Pyrrolidonderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee