ATE194606T1 - Diuretische piperidine derivate - Google Patents

Diuretische piperidine derivate

Info

Publication number
ATE194606T1
ATE194606T1 AT96909499T AT96909499T ATE194606T1 AT E194606 T1 ATE194606 T1 AT E194606T1 AT 96909499 T AT96909499 T AT 96909499T AT 96909499 T AT96909499 T AT 96909499T AT E194606 T1 ATE194606 T1 AT E194606T1
Authority
AT
Austria
Prior art keywords
diuretic
piperidine derivatives
alkyl
excretion
increase
Prior art date
Application number
AT96909499T
Other languages
English (en)
Inventor
Stephen J Humphrey
James T Curry
Eric Jon Jacobsen
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of ATE194606T1 publication Critical patent/ATE194606T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT96909499T 1995-04-27 1996-03-11 Diuretische piperidine derivate ATE194606T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42975195A 1995-04-27 1995-04-27
US08/468,129 US5716970A (en) 1995-04-27 1995-06-06 Diuretic compound
PCT/US1996/002321 WO1996033985A1 (en) 1995-04-27 1996-03-11 Piperidine derivatives as diuretic

Publications (1)

Publication Number Publication Date
ATE194606T1 true ATE194606T1 (de) 2000-07-15

Family

ID=27028330

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96909499T ATE194606T1 (de) 1995-04-27 1996-03-11 Diuretische piperidine derivate

Country Status (11)

Country Link
US (1) US5716970A (de)
EP (1) EP0822932B1 (de)
JP (1) JPH11504322A (de)
AT (1) ATE194606T1 (de)
AU (1) AU5297296A (de)
DE (1) DE69609323T2 (de)
DK (1) DK0822932T3 (de)
ES (1) ES2148745T3 (de)
GR (1) GR3034511T3 (de)
PT (1) PT822932E (de)
WO (1) WO1996033985A1 (de)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL254248A (de) * 1959-07-29
IL99320A (en) * 1990-09-05 1995-07-31 Sanofi Sa Arylalkylamines, their preparation and pharmaceutical preparations containing them
GB9310713D0 (en) * 1993-05-24 1993-07-07 Zeneca Ltd Aryl substituted heterocycles

Also Published As

Publication number Publication date
EP0822932B1 (de) 2000-07-12
PT822932E (pt) 2000-10-31
US5716970A (en) 1998-02-10
DE69609323D1 (de) 2000-08-17
ES2148745T3 (es) 2000-10-16
GR3034511T3 (en) 2000-12-29
DK0822932T3 (da) 2000-10-02
EP0822932A1 (de) 1998-02-11
DE69609323T2 (de) 2000-12-14
WO1996033985A1 (en) 1996-10-31
JPH11504322A (ja) 1999-04-20
AU5297296A (en) 1996-11-18

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee