ATE187338T1 - Zusammensetzung die sowohl eine lösliche als auch eine unlösliche form eines immunogens beinhaltet - Google Patents
Zusammensetzung die sowohl eine lösliche als auch eine unlösliche form eines immunogens beinhaltetInfo
- Publication number
- ATE187338T1 ATE187338T1 AT93307185T AT93307185T ATE187338T1 AT E187338 T1 ATE187338 T1 AT E187338T1 AT 93307185 T AT93307185 T AT 93307185T AT 93307185 T AT93307185 T AT 93307185T AT E187338 T1 ATE187338 T1 AT E187338T1
- Authority
- AT
- Austria
- Prior art keywords
- immunogen
- antigen
- forms
- soluble
- composition including
- Prior art date
Links
- 230000002163 immunogen Effects 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000000427 antigen Substances 0.000 abstract 7
- 102000036639 antigens Human genes 0.000 abstract 7
- 108091007433 antigens Proteins 0.000 abstract 7
- 230000028993 immune response Effects 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 1
- 241000712461 unidentified influenza virus Species 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0225—Spirochetes, e.g. Treponema, Leptospira, Borrelia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55588—Adjuvants of undefined constitution
- A61K2039/55594—Adjuvants of undefined constitution from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6018—Lipids, e.g. in lipopeptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Radar Systems Or Details Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
- Jib Cranes (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94317392A | 1992-09-14 | 1992-09-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE187338T1 true ATE187338T1 (de) | 1999-12-15 |
Family
ID=25479200
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT93307185T ATE187338T1 (de) | 1992-09-14 | 1993-09-13 | Zusammensetzung die sowohl eine lösliche als auch eine unlösliche form eines immunogens beinhaltet |
Country Status (15)
Country | Link |
---|---|
US (4) | US5662909A (de) |
EP (1) | EP0588578B2 (de) |
JP (1) | JP2512689B2 (de) |
AT (1) | ATE187338T1 (de) |
AU (1) | AU677592B2 (de) |
CA (1) | CA2105629A1 (de) |
DE (1) | DE69327214T3 (de) |
DK (1) | DK0588578T4 (de) |
ES (1) | ES2141750T5 (de) |
FI (1) | FI110234B (de) |
GR (1) | GR3032543T3 (de) |
IL (2) | IL106968A (de) |
NO (1) | NO313178B1 (de) |
PT (1) | PT588578E (de) |
ZA (1) | ZA936629B (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6967088B1 (en) * | 1995-03-16 | 2005-11-22 | Allergan, Inc. | Soluble recombinant botulinum toxin proteins |
ZA964896B (en) * | 1995-06-07 | 1997-01-08 | Connaught Lab | Expression of lipoproteins |
US6251405B1 (en) * | 1995-06-07 | 2001-06-26 | Connaught Laboratories, Inc. | Immunological combination compositions and methods |
CA2358385C (en) | 1998-12-31 | 2013-08-06 | Chiron Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
US7935805B1 (en) * | 1998-12-31 | 2011-05-03 | Novartis Vaccines & Diagnostics, Inc | Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof |
EP1141313A2 (de) | 1998-12-31 | 2001-10-10 | Chiron Corporation | Verbesserte exprimierung von hiv polypeptiden und herstellung von virusähnliche partikeln |
AU2596600A (en) | 1998-12-31 | 2000-07-31 | Chiron Corporation | Modified hiv env polypeptides |
US20050106137A1 (en) * | 2000-05-05 | 2005-05-19 | Stephen Grimes | Chimeric peptide immunogens |
CA2708703C (en) * | 2000-12-27 | 2012-12-04 | Alan Bruce Montgomery | Inhalable aztreonam for treatment and prevention of pulmonary bacterial infections |
EP1411770A4 (de) | 2001-07-05 | 2006-05-10 | Chiron Corp | Polynukleotide, die für antigene hiv-polypeptide des c-typs codieren, polypeptide und ihre verwendung |
EP2280074A3 (de) * | 2001-07-05 | 2011-06-22 | Novartis Vaccines and Diagnostics, Inc. | Antigene typ-b- und/oder typ-c-hiv-polypeptide codierende polynukleotide, polypeptide und deren verwendungen |
US20030170614A1 (en) * | 2001-08-31 | 2003-09-11 | Megede Jan Zur | Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof |
WO2003020876A2 (en) * | 2001-08-31 | 2003-03-13 | Chiron Corporation | Polynucleotides encoding antigenic hiv type b polypeptides, polypeptides and uses thereof |
US7211258B2 (en) * | 2002-04-10 | 2007-05-01 | Protalex, Inc. | Protein A compositions and methods of use |
US7425331B2 (en) * | 2002-04-10 | 2008-09-16 | Protalex, Inc. | Protein A methods of use |
US6814729B2 (en) | 2002-06-27 | 2004-11-09 | Technovision Gmbh | Laser vision correction apparatus and control method |
AU2011230619C1 (en) | 2010-03-25 | 2016-06-23 | Oregon Health & Science University | CMV glycoproteins and recombinant vectors |
LT2691530T (lt) | 2011-06-10 | 2018-08-10 | Oregon Health & Science University | Cmv glikoproteinai ir rekombinantiniai vektoriai |
US20130189754A1 (en) | 2011-09-12 | 2013-07-25 | International Aids Vaccine Initiative | Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies |
US9402894B2 (en) | 2011-10-27 | 2016-08-02 | International Aids Vaccine Initiative | Viral particles derived from an enveloped virus |
EP2679596B1 (de) | 2012-06-27 | 2017-04-12 | International Aids Vaccine Initiative | HIV-1 Env-proteinvariante |
US20150065381A1 (en) | 2013-09-05 | 2015-03-05 | International Aids Vaccine Initiative | Methods of identifying novel hiv-1 immunogens |
US10058604B2 (en) | 2013-10-07 | 2018-08-28 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
US10174292B2 (en) | 2015-03-20 | 2019-01-08 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
EP3072901A1 (de) | 2015-03-23 | 2016-09-28 | International Aids Vaccine Initiative | Lösliche hiv-1-hüllglykoproteintrimere |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4496538A (en) * | 1982-07-06 | 1985-01-29 | Connaught Laboratories, Inc. | Haemophilus influenzae b polysaccharide-diphtheria toxoid conjugate vaccine |
US4619828A (en) * | 1982-07-06 | 1986-10-28 | Connaught Laboratories, Inc. | Polysaccharide exotoxoid conjugate vaccines |
GB8610983D0 (en) * | 1986-05-06 | 1986-06-11 | Connaught Lab | Enhancement of antigen immunogenicity |
US4946676A (en) * | 1986-08-27 | 1990-08-07 | De Staat Der Nederlanden | Vaccine comprising an immunogenic protein and, as an adjuvant, a substantially non-immunogenic, sequentially homologous peptide |
EP0270295A3 (de) * | 1986-12-03 | 1989-08-02 | Connaught Laboratories Limited | Konjugat-Impfstoff |
DK425789A (da) * | 1988-08-31 | 1990-03-01 | Smithkline Beecham Corp | Vaccinale polypeptider |
JPH0678245B2 (ja) * | 1989-07-04 | 1994-10-05 | 東興薬品工業株式会社 | 鼻腔内噴霧投与用インフルエンザワクチンゲル製剤 |
WO1992000055A1 (en) * | 1990-06-15 | 1992-01-09 | Yale University | Compositions and methods for the prevention and diagnosis of lyme disease |
PT100980B (pt) * | 1991-10-18 | 1999-07-30 | Connaught Lab | Proteinas recombinantes de borrelia, seu processo de producao, vacina contra infeccao por borrelia e agente de imunodiagnostico para a sua deteccao |
-
1993
- 1993-09-07 CA CA002105629A patent/CA2105629A1/en not_active Abandoned
- 1993-09-08 AU AU46226/93A patent/AU677592B2/en not_active Ceased
- 1993-09-08 ZA ZA936629A patent/ZA936629B/xx unknown
- 1993-09-10 IL IL10696893A patent/IL106968A/en not_active IP Right Cessation
- 1993-09-13 DK DK93307185T patent/DK0588578T4/da active
- 1993-09-13 ES ES93307185T patent/ES2141750T5/es not_active Expired - Lifetime
- 1993-09-13 NO NO19933261A patent/NO313178B1/no unknown
- 1993-09-13 PT PT93307185T patent/PT588578E/pt unknown
- 1993-09-13 DE DE69327214T patent/DE69327214T3/de not_active Expired - Fee Related
- 1993-09-13 EP EP93307185A patent/EP0588578B2/de not_active Expired - Lifetime
- 1993-09-13 AT AT93307185T patent/ATE187338T1/de not_active IP Right Cessation
- 1993-09-14 JP JP5229041A patent/JP2512689B2/ja not_active Expired - Lifetime
- 1993-09-14 FI FI934013A patent/FI110234B/fi not_active IP Right Cessation
-
1995
- 1995-02-08 US US08/385,587 patent/US5662909A/en not_active Expired - Fee Related
- 1995-06-06 US US08/470,278 patent/US5837264A/en not_active Expired - Lifetime
-
1997
- 1997-02-18 US US08/801,152 patent/US5853736A/en not_active Expired - Fee Related
-
1998
- 1998-11-17 US US09/193,682 patent/US6024963A/en not_active Expired - Lifetime
-
1999
- 1999-05-23 IL IL13007599A patent/IL130075A0/xx unknown
-
2000
- 2000-02-02 GR GR20000400239T patent/GR3032543T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0588578B2 (de) | 2005-04-13 |
FI934013A (fi) | 1994-03-15 |
AU4622693A (en) | 1994-03-24 |
EP0588578B1 (de) | 1999-12-08 |
ES2141750T5 (es) | 2005-12-01 |
CA2105629A1 (en) | 1994-03-15 |
DK0588578T4 (da) | 2005-07-25 |
GR3032543T3 (en) | 2000-05-31 |
DK0588578T3 (da) | 2000-03-27 |
DE69327214D1 (de) | 2000-01-13 |
FI934013A0 (fi) | 1993-09-14 |
IL106968A0 (en) | 1993-12-28 |
FI110234B (fi) | 2002-12-31 |
IL130075A0 (en) | 2000-02-29 |
ZA936629B (en) | 1994-03-30 |
US5662909A (en) | 1997-09-02 |
JPH06192125A (ja) | 1994-07-12 |
AU677592B2 (en) | 1997-05-01 |
DE69327214T2 (de) | 2000-09-07 |
DE69327214T3 (de) | 2005-12-01 |
EP0588578A1 (de) | 1994-03-23 |
JP2512689B2 (ja) | 1996-07-03 |
PT588578E (pt) | 2000-05-31 |
ES2141750T3 (es) | 2000-04-01 |
US6024963A (en) | 2000-02-15 |
NO933261D0 (no) | 1993-09-13 |
NO933261L (no) | 1994-03-15 |
NO313178B1 (no) | 2002-08-26 |
US5853736A (en) | 1998-12-29 |
US5837264A (en) | 1998-11-17 |
IL106968A (en) | 1999-10-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
UEP | Publication of translation of european patent specification |
Ref document number: 0588578 Country of ref document: EP |
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REN | Ceased due to non-payment of the annual fee |