ATE185271T1 - Behandlung von durch talgdrüse verursachten erkrankungen mit inhibitoren der acyl coa cholesterin acyltransferase - Google Patents

Behandlung von durch talgdrüse verursachten erkrankungen mit inhibitoren der acyl coa cholesterin acyltransferase

Info

Publication number
ATE185271T1
ATE185271T1 AT95305594T AT95305594T ATE185271T1 AT E185271 T1 ATE185271 T1 AT E185271T1 AT 95305594 T AT95305594 T AT 95305594T AT 95305594 T AT95305594 T AT 95305594T AT E185271 T1 ATE185271 T1 AT E185271T1
Authority
AT
Austria
Prior art keywords
diseases caused
acyl coa
coa cholesterol
inhibitors
treatment
Prior art date
Application number
AT95305594T
Other languages
English (en)
Inventor
James T Mayne
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE185271T1 publication Critical patent/ATE185271T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
AT95305594T 1994-08-31 1995-08-10 Behandlung von durch talgdrüse verursachten erkrankungen mit inhibitoren der acyl coa cholesterin acyltransferase ATE185271T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/298,735 US6133326A (en) 1994-08-31 1994-08-31 Compositions and methods for decreasing sebum production

Publications (1)

Publication Number Publication Date
ATE185271T1 true ATE185271T1 (de) 1999-10-15

Family

ID=23151816

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95305594T ATE185271T1 (de) 1994-08-31 1995-08-10 Behandlung von durch talgdrüse verursachten erkrankungen mit inhibitoren der acyl coa cholesterin acyltransferase

Country Status (9)

Country Link
US (2) US6133326A (de)
EP (1) EP0699439B1 (de)
JP (2) JP3266473B2 (de)
AT (1) ATE185271T1 (de)
CA (1) CA2157142C (de)
DE (1) DE69512589T2 (de)
DK (1) DK0699439T3 (de)
ES (1) ES2136252T3 (de)
GR (1) GR3031917T3 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6080408A (en) * 1994-08-22 2000-06-27 Connaught Laboratories Limited Human immunodeficiency virus type 1 nucleic acids devoid of long terminal repeats capable of encoding for non-infectious, immunogenic, retrovirus-like particles
KR20010099975A (ko) * 1998-12-28 2001-11-09 우에하라 아끼라 외용제
US20030077301A1 (en) * 1999-12-16 2003-04-24 Maibach Howard I. Topical pharmaceutical composition for the treatment of inflammatory dermatoses
ATE295724T1 (de) * 2000-02-02 2005-06-15 Warner Lambert Co Der duale inhibitor der cholesterylester und wachsester synthese avasimibe zur behandlung von erkrankungen des talgdrüse
EP1408902A4 (de) * 2001-06-22 2008-02-13 Millard Marsden Mershon Zusammensetzungen und verfahren zur reduzierung des flüssigkeits- und blutverlustes aus offenen wunden
EP1281399A3 (de) * 2001-08-01 2004-02-11 Warner-Lambert Company Hemmer mit doppelter Wirkung auf Wachsester- und Cholesterylestersynthese zur Hemmung der Sebumproduktion
PT1485080E (pt) * 2002-03-12 2009-07-31 Galderma Res & Dev Utilização de adapaleno para o tratamento de desordens dermatológicas
JP2009102358A (ja) * 2003-07-29 2009-05-14 Rohto Pharmaceut Co Ltd 皮膚外用剤
JP2005060386A (ja) * 2003-07-29 2005-03-10 Rohto Pharmaceut Co Ltd 皮膚外用剤
WO2005034931A1 (en) 2003-10-09 2005-04-21 Warner-Lambert Company Llc Pharmaceutical compositions comprising malonamide derivatives for decreasing sebum production
AU2006217529C1 (en) * 2005-02-24 2013-03-07 Medicis Pharmaceutical Corporation Crystalline ACAT inhibitor
FR2918889B1 (fr) * 2007-07-19 2009-10-23 Galderma Res & Dev Utilisation de l'eflucimibe pour la preparation d'un medicament destine a prevenir ou a traiter une maladie due a un dysfonctionnement des glandes sebacees chez l'homme ou l'animal
FR2918890A1 (fr) * 2007-07-19 2009-01-23 Galderma Res & Dev Utilisation du pactimibe pour la preparation d'un medicament destine a prevenir ou a traiter une maladie due a un dysfonctionnement des glandes sebacees chez l'homme ou l'animal
FR2920769B1 (fr) 2007-09-06 2009-10-30 Galderma Res & Dev Nouveaux derives de n-phenyl acetamide, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contenant
FR2920771B1 (fr) * 2007-09-06 2009-10-30 Galderma Res & Dev Nouveaux derives de phenylurees, inhibiteurs de l'enzymes soat-1, compositions pharmaceutiques et cosmetiques les contenant
CN101502541B (zh) * 2008-02-04 2011-12-28 成都地奥九泓制药厂 安息香属植物及其提取物的用途
FR2946340B1 (fr) 2009-06-05 2011-06-24 Galderma Res & Dev Nouveaux n-phenyl acetamie, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contenant.
FR2946345B1 (fr) 2009-06-05 2011-05-20 Galderma Res & Dev Nouveaux derives dioxo-imidazolidine, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contenant.
FR2946346B1 (fr) 2009-06-05 2011-05-20 Galderma Res & Dev Nouveaux derives dioxo-imidazolidine, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contenant.
FR2946342B1 (fr) 2009-06-05 2011-06-24 Galderma Res & Dev Nouveaux derives de dioxo-imidazolidine, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contenant.
US11865113B2 (en) 2016-06-06 2024-01-09 Lipidio Pharmaceuticals Inc. Methods of treating a patient afflicted with non-alcoholic steatohepatitis (NASH)

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3729568A (en) 1969-09-23 1973-04-24 Johnson & Johnson Acne treatment
US4302456A (en) * 1977-04-13 1981-11-24 The Upjohn Company Process for therapeutic treatment
US4514385A (en) * 1981-10-05 1985-04-30 Alcon Laboratories, Inc. Anti-acne compositions
EP0170105B1 (de) 1984-07-07 1990-10-17 Koichi Prof. Dr. Shudo Benzoesäurederivate
LU86258A1 (fr) 1986-01-21 1987-09-03 Rech Dermatologiques C I R D S Composes benzamido aromatique,leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique
US4751026A (en) 1986-03-24 1988-06-14 Warner-Lambert Company Substituted anilides of oleic, linoleic, or linolenic acid as inhibitors of acyl-coa:cholesterol acyltransferase
US4722927A (en) 1986-04-28 1988-02-02 Warner-Lambert Company Pyrimidine amides of oleic or linoleic acid, composition containing them and their use as inhibitors of acyl-CoA cholesterol acyltransferase
EP0252524A3 (de) 1986-07-11 1989-04-19 Warner-Lambert Company Aryl- und Aralkylamid-Derivate von Omega-(substituiertes phenyloxy)-alkansäuren als Acyl-CoA: Cholesterol-Acyltransferasehemmer und diese enthaltende pharmazeutische Zusammensetzungen
US4716175A (en) * 1987-02-24 1987-12-29 Warner-Lambert Company Saturated fatty acid amides as inhibitors of acyl-CoA:cholesterol acyltransferase
US4743605A (en) 1987-02-24 1988-05-10 Warner-Lambert Company Saturated fatty acid amides as inhibitors of acyl-coa:cholesterol acyltransferase
IE61716B1 (en) 1987-06-02 1994-11-30 Warner Lambert Co Antihyperlipidemic and antiatherosclerotic urea compounds
US5015644A (en) 1987-06-02 1991-05-14 Warner-Lambert Company Antihyperlipidemic and antiatherosclerotic urea and carbamate compounds
DE3861988D1 (en) 1987-07-02 1991-04-18 Warner Lambert Co N-((2,6-disubstituierte)-phenyl)-harnstoff und -carbamat-inhibitoren der acyl-coenzym a:cholesterol-acyltransferase.
US5116848A (en) 1988-03-30 1992-05-26 Warner-Lambert Company N-(((2,6-disubstituted)phenyl)-n-diarylalkyl)ureas as antihyperlipidemic and antiatherosclerotic agents
US4868210A (en) 1988-03-30 1989-09-19 Warner-Lambert Company Antihyperlipidemic and antiatherosclerotic compounds and compositions
US5155127A (en) 1989-02-09 1992-10-13 Warner-Lambert Company N-(substituted aryl)-n'-(substituted alkoxy)-ureas and thioureas as antihypercholesterolemic and antiatherosclerotic agents
US4994465A (en) * 1989-02-17 1991-02-19 Warner-Lambert Company Antihyperlipidemic and antiatherosclerotic trisubstituted urea compounds
US5204093A (en) * 1989-04-06 1993-04-20 Victor Steven A Shaving cream composition for the treatment of acne vulgaris and pseudofolliculitis barbae and method of producing and using same
AU632809B2 (en) 1989-05-25 1993-01-14 Takeda Chemical Industries Ltd. Benzocycloalkane benzopyran and benzothiopyran urea derivatives and production thereof
CA2022346A1 (en) 1989-08-04 1991-02-05 Mitsubishi Chemical Corporation 1-phenylalkyl-3-phenylurea derivatives
MX22406A (es) 1989-09-15 1994-01-31 Pfizer Nuevos derivados de n-aril y n-heteroarilamidas y urea como inhibidores de acil coenzima a: acil transferasa del colesterol (acat).
TW205037B (de) 1989-10-06 1993-05-01 Takeda Pharm Industry Co Ltd
JPH05310678A (ja) 1990-01-22 1993-11-22 Mitsubishi Kasei Corp １−フェニルアルキル−３−フェニル尿素誘導体
JP2668163B2 (ja) * 1992-01-23 1997-10-27 ファイザー インク． コレステロール血症および抗アテローム動脈硬化症薬としての４−アリール−３−（ヘテロアリールウレイド）−１，２−ジヒドロ−２−オキソ−キノリン誘導体
CA2134359C (en) * 1992-05-28 1997-07-01 Ernest S. Hamanaka New n-aryl and n-heteroarylurea derivatives as inhibitors of acyl coenzyme a: cholesterol acyl transferase (acat)
US5902805A (en) * 1996-04-22 1999-05-11 L'oreal Method for treatment of acne and/or the effects of ageing using HMG-coenzyme A-reductase inhibitor and compositions for performing the same
US5965553A (en) * 1996-06-20 1999-10-12 Pfizer Inc. Squalene synthetase inhibitors
US5834480A (en) * 1997-06-13 1998-11-10 Elkhoury; George F. Topical application of opioids for treatment of acne and sebaceous gland disorders
US5994330A (en) * 1998-11-09 1999-11-30 El Khoury; Georges F. Topical application of muscarinic agents such as neostigmine for treatment of acne and other inflammatory conditions
US9206485B2 (en) 2011-08-19 2015-12-08 J. Edwin Roy Portable sugar mill
US9303539B1 (en) 2012-06-10 2016-04-05 Ags I-Prop, Llc Universal drain plug system and method
US9210886B2 (en) 2014-03-27 2015-12-15 Monsanto Technology Llc Plants and seeds of corn variety CV410274

Also Published As

Publication number Publication date
GR3031917T3 (en) 2000-03-31
EP0699439A3 (de) 1996-06-26
US6133326A (en) 2000-10-17
ES2136252T3 (es) 1999-11-16
CA2157142A1 (en) 1996-03-01
JP2002053494A (ja) 2002-02-19
JPH0899903A (ja) 1996-04-16
US6271268B1 (en) 2001-08-07
DK0699439T3 (da) 1999-12-27
EP0699439B1 (de) 1999-10-06
DE69512589T2 (de) 2000-01-27
JP3266473B2 (ja) 2002-03-18
EP0699439A2 (de) 1996-03-06
CA2157142C (en) 1998-06-09
DE69512589D1 (de) 1999-11-11

Similar Documents

Publication Publication Date Title
ATE185271T1 (de) Behandlung von durch talgdrüse verursachten erkrankungen mit inhibitoren der acyl coa cholesterin acyltransferase
ATE332687T1 (de) Liponsäure in topischen mittel
UY25322A1 (es) Compuestos de tiourea y benzamida,composiciones y metodos para tratar y prevenir enfermedades inflamatorias y aterosclerosis
DE69939651D1 (de) Behandlung hyperproliferativer erkrankungen
BR9809115A (pt) Métodos para tratar inflamação e doenças inflamatórias usando inibidores de padprt
ATE173630T1 (de) Behandlung von entzündlichen darmerkrankungen mit interferon-gamma-inhibitoren
PT971713E (pt) Utilizacao de inibidores da colinesterase para tratamento de desordens da atencao
EA199900137A1 (ru) Замещенные пиридины в качестве избирательных ингибиторов циклооксигеназы-2
DE69529690D1 (de) Diaryl-2(5h)-fuaranone als cox-2-inhibitoren
DE69617469D1 (de) Behandlung von multipler sklerose
GEP20033044B (en) Method for Treating Atherosclerosis
CA2002859A1 (en) Method of treating epithelial disorders
BR9712792A (pt) Inibidores de metaloprotease bidentada.
WO1992019617A3 (en) Substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
DE59608698D1 (de) Pharmazeutische Zubereitung zur Behandlung akuter Rhinitiden, enthaltend Sympthomimeticum und Pantothenol und/oder Pantothensäure
ES2106531T3 (es) Compuestos de dibenzoxazepina substituidos en 2, 3, 4, 5, 6, 7, 8, 9 y/o 10, composiciones farmaceuticas y metodos de uso.
EA199800717A1 (ru) Способ лечения заболеваний млекопитающих и цвиттерионная композиция
BR0110396A (pt) Métodos para prevenir e tratar alopecia induzida por quimioterapia ou radioterapia
DE69736945D1 (de) Biphenylverbindungen sowie ihre anwendung als östrogene mittel
ATE251631T1 (de) Dipohosphonsäuresalze für die behandlung von osteoporose
DE69822626D1 (de) Verwendung eines nitroxids oder seiner prodrugs zur prophylaktischen und therapeutischen behandlung von krebs
BR0107954A (pt) Inibidores duplos de sìntese de éster de colesterol e éster de cera para distúrbios de glândula sebácea
DE69829861D1 (de) 2-aminopyridine als inhibitoren von cyclooxygenase-2
NO923198L (no) Terapeutiske midler
GEP20032956B (en) Miticide Composition

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee