ATE181965T1 - Reagenzien, die einen nichtspezifischen bindungshemmer in einem ioneneinfang-assay enthalten - Google Patents
Reagenzien, die einen nichtspezifischen bindungshemmer in einem ioneneinfang-assay enthaltenInfo
- Publication number
- ATE181965T1 ATE181965T1 AT92913618T AT92913618T ATE181965T1 AT E181965 T1 ATE181965 T1 AT E181965T1 AT 92913618 T AT92913618 T AT 92913618T AT 92913618 T AT92913618 T AT 92913618T AT E181965 T1 ATE181965 T1 AT E181965T1
- Authority
- AT
- Austria
- Prior art keywords
- solid phase
- reagent
- capture reagent
- capture
- nonspecific binding
- Prior art date
Links
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 10
- 230000009871 nonspecific binding Effects 0.000 title abstract 4
- 238000003556 assay Methods 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 title 1
- 239000007790 solid phase Substances 0.000 abstract 4
- 239000012491 analyte Substances 0.000 abstract 3
- 239000000463 material Substances 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- NBTMNFYXJYCQHQ-UHFFFAOYSA-N (2,3,4,5,6-pentasulfooxycyclohexyl) hydrogen sulfate Chemical compound OS(=O)(=O)OC1C(OS(O)(=O)=O)C(OS(O)(=O)=O)C(OS(O)(=O)=O)C(OS(O)(=O)=O)C1OS(O)(=O)=O NBTMNFYXJYCQHQ-UHFFFAOYSA-N 0.000 abstract 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 abstract 1
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- 229920002307 Dextran Polymers 0.000 abstract 1
- 239000001116 FEMA 4028 Substances 0.000 abstract 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 1
- 125000000129 anionic group Chemical group 0.000 abstract 1
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 abstract 1
- 235000011175 beta-cyclodextrine Nutrition 0.000 abstract 1
- 229960004853 betadex Drugs 0.000 abstract 1
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 abstract 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 abstract 1
- 229940105329 carboxymethylcellulose Drugs 0.000 abstract 1
- 125000002091 cationic group Chemical group 0.000 abstract 1
- 230000002860 competitive effect Effects 0.000 abstract 1
- 229960002086 dextran Drugs 0.000 abstract 1
- 229960000633 dextran sulfate Drugs 0.000 abstract 1
- 229960002897 heparin Drugs 0.000 abstract 1
- 229920000669 heparin Polymers 0.000 abstract 1
- 230000002452 interceptive effect Effects 0.000 abstract 1
- -1 pentosan polysulfate Chemical compound 0.000 abstract 1
- 229940043138 pentosan polysulfate Drugs 0.000 abstract 1
- 230000009870 specific binding Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
- G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70737291A | 1991-05-30 | 1991-05-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE181965T1 true ATE181965T1 (de) | 1999-07-15 |
Family
ID=24841445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92913618T ATE181965T1 (de) | 1991-05-30 | 1992-04-10 | Reagenzien, die einen nichtspezifischen bindungshemmer in einem ioneneinfang-assay enthalten |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0586590B1 (de) |
| JP (1) | JP3267613B2 (de) |
| AT (1) | ATE181965T1 (de) |
| CA (1) | CA2109924A1 (de) |
| DE (1) | DE69229551T2 (de) |
| ES (1) | ES2136090T3 (de) |
| WO (1) | WO1992021769A1 (de) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5670381A (en) * | 1988-01-29 | 1997-09-23 | Abbott Laboratories | Devices for performing ion-capture binding assays |
| WO1995025282A1 (en) * | 1994-03-15 | 1995-09-21 | Abbott Laboratories | Ion-capture reagents and methods for performing binding assays |
| US5707799A (en) * | 1994-09-30 | 1998-01-13 | Abbott Laboratories | Devices and methods utilizing arrays of structures for analyte capture |
| FR2751989B1 (fr) * | 1996-08-01 | 1998-10-30 | Soc D Rech Et De Dev En Activa | Methode d'identification de cellules eucaryotes par fixation desdites cellules sur un support et support pour mettre en oeuvre ladite methode |
| IL121116A (en) * | 1997-06-19 | 2000-12-06 | Savyon Diagnostics Ltd | Stabilization of polypeptides for use in immunoassay procedures |
| DE10013794A1 (de) * | 2000-03-15 | 2001-10-11 | Gluesenkamp Karl Heinz | Herstellung, Stabilisierung und Anwendung einer neuen Art von chemisch aktivierten Oberflächen |
| AU2001273264A1 (en) * | 2000-07-21 | 2002-02-05 | Cuno, Incorporated | Improved blocking chemistries for nylon membrane |
| FR2825700B1 (fr) * | 2001-06-12 | 2003-09-05 | Centre Nat Rech Scient | Procede d'immobilisation reversible de macromolecules biologiques et dispositif pour sa mise en oeuvre |
| US7947467B2 (en) | 2001-07-19 | 2011-05-24 | Common Sense Ltd. | Methods for monitoring pathological conditions in a female subject |
| US6837171B1 (en) | 2002-04-29 | 2005-01-04 | Palmer/Snyder Furniture Company | Lightweight table with unitized table top |
| US7285424B2 (en) | 2002-08-27 | 2007-10-23 | Kimberly-Clark Worldwide, Inc. | Membrane-based assay devices |
| US7314763B2 (en) | 2002-08-27 | 2008-01-01 | Kimberly-Clark Worldwide, Inc. | Fluidics-based assay devices |
| US7432105B2 (en) | 2002-08-27 | 2008-10-07 | Kimberly-Clark Worldwide, Inc. | Self-calibration system for a magnetic binding assay |
| US7781172B2 (en) | 2003-11-21 | 2010-08-24 | Kimberly-Clark Worldwide, Inc. | Method for extending the dynamic detection range of assay devices |
| US7247500B2 (en) | 2002-12-19 | 2007-07-24 | Kimberly-Clark Worldwide, Inc. | Reduction of the hook effect in membrane-based assay devices |
| US20040197819A1 (en) | 2003-04-03 | 2004-10-07 | Kimberly-Clark Worldwide, Inc. | Assay devices that utilize hollow particles |
| US7851209B2 (en) | 2003-04-03 | 2010-12-14 | Kimberly-Clark Worldwide, Inc. | Reduction of the hook effect in assay devices |
| GB0312403D0 (en) * | 2003-05-29 | 2003-07-02 | Axis Shield Asa | Assay |
| US7943395B2 (en) | 2003-11-21 | 2011-05-17 | Kimberly-Clark Worldwide, Inc. | Extension of the dynamic detection range of assay devices |
| US7713748B2 (en) | 2003-11-21 | 2010-05-11 | Kimberly-Clark Worldwide, Inc. | Method of reducing the sensitivity of assay devices |
| US7943089B2 (en) | 2003-12-19 | 2011-05-17 | Kimberly-Clark Worldwide, Inc. | Laminated assay devices |
| US7521226B2 (en) | 2004-06-30 | 2009-04-21 | Kimberly-Clark Worldwide, Inc. | One-step enzymatic and amine detection technique |
| WO2006041392A1 (en) * | 2004-10-13 | 2006-04-20 | Biacore Ab | Preparation and use of a reactive solid support surface |
| SE0402476D0 (sv) | 2004-10-13 | 2004-10-13 | Biacore Ab | Preparation and use of a reactive solid support surface |
| CA2667992A1 (en) * | 2006-10-31 | 2008-05-08 | Sru Biosystems, Inc. | Method for blocking non-specific protein binding on a functionalized surface |
| US8617820B2 (en) * | 2007-08-28 | 2013-12-31 | Ortho-Clinical Diagnostics, Inc. | Use of glycosaminoglycans to reduce non-specific binding in immunoassays |
| CN101424682B (zh) * | 2007-10-30 | 2013-01-02 | 江苏三联生物工程有限公司 | 一种生物芯片片基处理方法 |
| EP3925533B1 (de) | 2009-04-30 | 2024-04-10 | DexCom, Inc. | Mit kontinuierlichen sensordaten aus mehreren analysezeiträumen assoziierte leistungsberichte |
| WO2011057347A1 (en) | 2009-11-12 | 2011-05-19 | Tgr Biosciences Pty Ltd | Analyte detection |
| US9651549B2 (en) * | 2012-07-13 | 2017-05-16 | Genisphere, Llc | Lateral flow assays using DNA dendrimers |
| JP6182896B2 (ja) * | 2013-02-22 | 2017-08-23 | 東洋紡株式会社 | イムノアッセイ方法 |
| JP6346265B2 (ja) | 2013-03-21 | 2018-06-20 | ジェニスフィア・エルエルシー | Ｄｎａインターカレーティング剤の細胞送達 |
| EP2981258B8 (de) * | 2013-04-05 | 2020-11-11 | scPharmaceuticals Inc. | Pharmazeutische formulierungen zur subkutanen verabreichung von furosemid |
| CN105277656B (zh) | 2014-07-01 | 2018-12-25 | 科蒙森斯公司 | 用于鉴定羊水的诊断组合物 |
| IL260983B (en) | 2016-02-19 | 2022-07-01 | Genisphere Llc | Nucleic acid carriers and methods of medical use |
| US11422128B2 (en) * | 2016-04-13 | 2022-08-23 | Lsi Medience Corporation | Immunoassay employing sulfated polysaccharide |
| EP3260489B1 (de) | 2016-06-24 | 2019-12-25 | Borealis AG | Neuartige polypropylenzusammensetzungen mit niedriger verschleierung |
| KR102271108B1 (ko) | 2016-08-23 | 2021-06-29 | 후지필름 가부시키가이샤 | 발광성 입자 및 화합물 |
| CN110520732A (zh) | 2017-03-30 | 2019-11-29 | 富士胶片株式会社 | 用于对测定对象物质进行测定的试剂盒、方法及试剂 |
| WO2018181800A1 (ja) | 2017-03-30 | 2018-10-04 | 富士フイルム株式会社 | 生体試料中の測定対象物質を測定するためのキット及び方法 |
| KR20190120325A (ko) | 2017-03-30 | 2019-10-23 | 후지필름 가부시키가이샤 | 생체 시료 중의 측정 대상 물질을 측정하기 위한 키트 및 방법 |
| JP7203034B2 (ja) * | 2017-10-02 | 2023-01-12 | 大塚製薬株式会社 | アナライトの検出方法 |
| JP7355742B2 (ja) | 2018-01-18 | 2023-10-03 | フレッド ハッチンソン キャンサー センター | 細胞活性状態を調節することにより免疫細胞の炎症状態をインビボで変更すること |
| CN111758031B (zh) | 2018-02-22 | 2024-03-19 | 富士胶片株式会社 | 孕酮测定试剂盒、孕酮的测定方法及孕酮测定试剂 |
| ES3041602T3 (en) | 2018-12-10 | 2025-11-13 | Sq Innovation Ag | Pharmaceutical compositions of furosemide and uses thereof |
| US12397005B2 (en) | 2019-01-04 | 2025-08-26 | Sq Innovation Ag | Pharmaceutical compositions of torsemide and uses thereof |
| ES3058386T3 (es) | 2019-01-04 | 2026-03-10 | Sq Innovation Ag | Composiciones farmacéuticas de furosemida |
| JP7465881B2 (ja) | 2019-01-31 | 2024-04-11 | エスシーファーマシューティカルズ インコーポレイテッド | フロセミドの濃縮液体医薬製剤及びそれを投与する方法 |
| WO2020162474A1 (ja) * | 2019-02-06 | 2020-08-13 | 富士フイルム株式会社 | 測定対象物質を測定するためのキットおよび測定対象物質を測定する方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4121975A (en) * | 1976-08-20 | 1978-10-24 | Syva Company | Pretreatment of samples for polyiodothyronine assays |
| JPS57182169A (en) * | 1981-05-02 | 1982-11-09 | Mitsubishi Chem Ind Ltd | Measuring method for antigen-antibody reaction |
| US4530900A (en) * | 1982-09-13 | 1985-07-23 | Seragen Diagnostics Inc. | Soluble insoluble polymers in enzymeimmunoassay |
| JPS60500548A (ja) * | 1982-12-03 | 1985-04-18 | イ−・アイ・デユポン・ド・ネモア−ス・アンド・コンパニ− | 発色性支持体免疫測定法 |
| US4780409A (en) * | 1985-05-02 | 1988-10-25 | Genetic Systems Corporation | Thermally induced phase separation immunoassay |
| US4935147A (en) * | 1985-12-20 | 1990-06-19 | Syntex (U.S.A.) Inc. | Particle separation method |
| AU609241B2 (en) * | 1988-01-29 | 1991-04-26 | Abbott Laboratories | Ion-capture assays and devices |
| US5051356A (en) * | 1988-06-13 | 1991-09-24 | Eastman Kodak Company | Specific binding composition comprising a low pI protein or carbohydrate and a diagnostic test kit and method of use |
| US5094962A (en) * | 1988-06-13 | 1992-03-10 | Eastman Kodak Company | Microporous article having a stabilized specific binding reagent, a method for its use and a diagnostic test kit |
| JPH0750110B2 (ja) * | 1988-12-22 | 1995-05-31 | 積水化学工業株式会社 | 免疫測定法 |
| JPH0750108B2 (ja) * | 1988-12-26 | 1995-05-31 | 積水化学工業株式会社 | 免疫反応測定法 |
| CA1341592C (en) * | 1989-07-07 | 2009-04-14 | Abbott Laboratories | Ion capture reagents and methods for performing binding assays |
-
1992
- 1992-04-10 ES ES92913618T patent/ES2136090T3/es not_active Expired - Lifetime
- 1992-04-10 EP EP92913618A patent/EP0586590B1/de not_active Expired - Lifetime
- 1992-04-10 JP JP50039393A patent/JP3267613B2/ja not_active Expired - Fee Related
- 1992-04-10 AT AT92913618T patent/ATE181965T1/de not_active IP Right Cessation
- 1992-04-10 CA CA002109924A patent/CA2109924A1/en not_active Abandoned
- 1992-04-10 WO PCT/US1992/002979 patent/WO1992021769A1/en not_active Ceased
- 1992-04-10 DE DE69229551T patent/DE69229551T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69229551D1 (de) | 1999-08-12 |
| EP0586590B1 (de) | 1999-07-07 |
| CA2109924A1 (en) | 1992-12-10 |
| DE69229551T2 (de) | 2000-01-27 |
| JP3267613B2 (ja) | 2002-03-18 |
| EP0586590A4 (en) | 1996-01-17 |
| JPH06508210A (ja) | 1994-09-14 |
| WO1992021769A1 (en) | 1992-12-10 |
| EP0586590A1 (de) | 1994-03-16 |
| ES2136090T3 (es) | 1999-11-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |