ATE176728T1 - Substrat für oberflächenverstärkte verfahren und für spezifische verfahren hergestellte substrate - Google Patents
Substrat für oberflächenverstärkte verfahren und für spezifische verfahren hergestellte substrateInfo
- Publication number
- ATE176728T1 ATE176728T1 AT92917226T AT92917226T ATE176728T1 AT E176728 T1 ATE176728 T1 AT E176728T1 AT 92917226 T AT92917226 T AT 92917226T AT 92917226 T AT92917226 T AT 92917226T AT E176728 T1 ATE176728 T1 AT E176728T1
- Authority
- AT
- Austria
- Prior art keywords
- substrate
- binding partner
- processes
- coupling agent
- procedures
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
- G01N33/553—Metal or metal coated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Inorganic Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Laminated Bodies (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Reinforced Plastic Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73372891A | 1991-07-22 | 1991-07-22 | |
US85816392A | 1992-03-27 | 1992-03-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE176728T1 true ATE176728T1 (de) | 1999-02-15 |
Family
ID=27112619
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT92917226T ATE176728T1 (de) | 1991-07-22 | 1992-07-21 | Substrat für oberflächenverstärkte verfahren und für spezifische verfahren hergestellte substrate |
Country Status (6)
Country | Link |
---|---|
US (1) | US5527712A (de) |
EP (1) | EP0598003B1 (de) |
JP (1) | JPH07500413A (de) |
AT (1) | ATE176728T1 (de) |
DE (1) | DE69228421D1 (de) |
WO (1) | WO1993002362A1 (de) |
Families Citing this family (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5837552A (en) * | 1991-07-22 | 1998-11-17 | Medifor, Ltd. | Surface-enhanced analytical procedures and substrates |
AT403961B (de) * | 1995-03-17 | 1998-07-27 | Avl Verbrennungskraft Messtech | Optochemisches messsystem mit einem fluoreszenzsensor |
EP0795752B1 (de) * | 1996-03-13 | 2001-10-10 | F.Hoffmann-La Roche Ag | Optochemisches Verfahren und Messanordnung zur Messung der Konzentration eines Analyten |
US5945345A (en) * | 1996-08-27 | 1999-08-31 | Metrika, Inc. | Device for preventing assay interference using silver or lead to remove the interferant |
WO1999044045A1 (en) * | 1998-02-27 | 1999-09-02 | Massachusetts Institute Of Technology | Single molecule detection with surface-enhanced raman scattering and applications in dna or rna sequencing |
US6226082B1 (en) * | 1998-06-25 | 2001-05-01 | Amira Medical | Method and apparatus for the quantitative analysis of a liquid sample with surface enhanced spectroscopy |
US7123359B2 (en) * | 1999-05-17 | 2006-10-17 | Arrowhead Center, Inc. | Optical devices and methods employing nanoparticles, microcavities, and semicontinuous metal films |
US6608716B1 (en) | 1999-05-17 | 2003-08-19 | New Mexico State University Technology Transfer Corporation | Optical enhancement with nanoparticles and microcavities |
US20040023293A1 (en) * | 1999-09-27 | 2004-02-05 | Kreimer David I. | Biochips for characterizing biological processes |
US20030232388A1 (en) * | 1999-09-27 | 2003-12-18 | Kreimer David I. | Beads having identifiable Raman markers |
US20020132371A1 (en) * | 1999-09-27 | 2002-09-19 | Kreimer David I. | Amplification of analyte detection by substrates having particle structures with receptors |
US20010053521A1 (en) * | 1999-09-27 | 2001-12-20 | Kreimer David I. | Amplification of analyte detection by substrates having particle structures with receptors |
US6623977B1 (en) * | 1999-11-05 | 2003-09-23 | Real-Time Analyzers, Inc. | Material for surface-enhanced Raman spectroscopy, and SER sensors and method for preparing same |
US6406777B1 (en) * | 2000-06-14 | 2002-06-18 | The United States Of America As Represented By The Secretary Of The Navy | Metal and glass structure for use in surface enhanced Raman spectroscopy and method for fabricating same |
US20040126900A1 (en) * | 2001-04-13 | 2004-07-01 | Barry Stephen E | High affinity peptide- containing nanoparticles |
US8213007B2 (en) * | 2003-05-27 | 2012-07-03 | Optotrace Technologies, Inc. | Spectrally sensing chemical and biological substances |
US7242469B2 (en) * | 2003-05-27 | 2007-07-10 | Opto Trace Technologies, Inc. | Applications of Raman scattering probes |
US8031335B2 (en) * | 2003-05-27 | 2011-10-04 | Opto Trace Technologies, Inc. | Non-invasive disease diagnosis using light scattering probe |
US8102525B2 (en) * | 2008-10-07 | 2012-01-24 | OptoTrace (SuZhou) Technologies, Inc. | Systems and methods for detecting chemical and biological substances |
US7956997B2 (en) * | 2003-05-27 | 2011-06-07 | Optotrace Technologies, Inc. | Systems and methods for food safety detection |
US8081308B2 (en) * | 2003-05-27 | 2011-12-20 | Optotrace Technologies, Inc. | Detecting chemical and biological impurities by nano-structure based spectral sensing |
US20060240573A1 (en) * | 2003-07-29 | 2006-10-26 | Lamdagen, Llc | Optical system including nanostructures for biological or chemical sensing |
US7462496B2 (en) * | 2003-09-08 | 2008-12-09 | American Environmental System, Inc. | Plasmon-enhanced marking of fragile materials and other applications thereof |
DE102004037882A1 (de) * | 2003-12-19 | 2005-07-14 | Boraglas Gmbh | Glas mit geringer Eigenfloureszenz und hoher Strahlungsabsorption |
US7906344B2 (en) * | 2004-03-31 | 2011-03-15 | Omron Corporation | Localized plasmon resonance sensor and examining device |
US7307719B2 (en) * | 2004-09-14 | 2007-12-11 | Hewlett-Packard Development Company, L.P. | Wavelength-tunable excitation radiation amplifying structure and method |
US7177021B2 (en) * | 2004-09-14 | 2007-02-13 | Hewlett-Packard Development Company, L.P. | Integrated radiation sources and amplifying structures, and methods of using the same |
US7339666B2 (en) * | 2004-09-14 | 2008-03-04 | Hewlett-Packard Development Company, L.P. | Light-amplifying structures and methods for surface-enhanced Raman spectroscopy |
US7321422B2 (en) * | 2004-09-16 | 2008-01-22 | Hewlett-Packard Development Company, L.P. | SERS-active structures having nanoscale dimensions |
US7158219B2 (en) * | 2004-09-16 | 2007-01-02 | Hewlett-Packard Development Company, L.P. | SERS-active structures including nanowires |
US7332329B2 (en) * | 2004-09-24 | 2008-02-19 | Wisconsin Alumni Research Foundation | Versatile substrate for SPR detection |
US7245370B2 (en) * | 2005-01-06 | 2007-07-17 | Hewlett-Packard Development Company, L.P. | Nanowires for surface-enhanced Raman scattering molecular sensors |
US7236242B2 (en) * | 2005-01-27 | 2007-06-26 | Hewlett-Packard Development Company, L.P. | Nano-enhanced Raman spectroscopy-active nanostructures including elongated components and methods of making the same |
US7397558B2 (en) * | 2005-03-17 | 2008-07-08 | Hewlett-Packard Development Company, L.P. | Ordered array of nanoparticles for efficient nanoenhanced Raman scattering detection and methods of forming the same |
US7292334B1 (en) * | 2005-03-25 | 2007-11-06 | Hewlett-Packard Development Company, L.P. | Binary arrays of nanoparticles for nano-enhanced Raman scattering molecular sensors |
EP1902151A2 (de) * | 2005-07-14 | 2008-03-26 | 3M Innovative Properties Company | Wasserlösliches polymeres substrat mit metallnanopartikelbeschichtung |
US7342656B2 (en) * | 2005-10-17 | 2008-03-11 | Hewlett-Packard Development Company, L.P. | Dynamically variable separation among nanoparticles for nano-enhanced Raman spectroscopy (NERS) molecular sensing |
US7372562B2 (en) * | 2005-10-17 | 2008-05-13 | Hewlett-Packard Development Company, L.P. | Dynamic random separation among nanoparticles for nano enhanced Raman spectroscopy (NERS) molecular sensing |
US9182352B2 (en) | 2005-12-19 | 2015-11-10 | OptoTrace (SuZhou) Technologies, Inc. | System and method for detecting oil or gas underground using light scattering spectral analyses |
JP2007292598A (ja) * | 2006-04-25 | 2007-11-08 | Canon Inc | 標的物質検出用の素子及びそれを作製するための基体、ならびにそれを用いた標的物質の検出方法及び検出装置 |
US7511808B2 (en) * | 2006-04-27 | 2009-03-31 | Hewlett-Packard Development Company, L.P. | Analyte stages including tunable resonant cavities and Raman signal-enhancing structures |
US7388661B2 (en) * | 2006-10-20 | 2008-06-17 | Hewlett-Packard Development Company, L.P. | Nanoscale structures, systems, and methods for use in nano-enhanced raman spectroscopy (NERS) |
EP2092308A1 (de) * | 2006-12-05 | 2009-08-26 | Yeda Research And Development Company Limited | Vorrichtung und verfahren für optisches lokalisiertes plasmon-sensing |
US9557271B2 (en) * | 2008-09-25 | 2017-01-31 | Mohammad A. Mazed | Optical biomodule for detection of diseases |
US7391511B1 (en) | 2007-01-31 | 2008-06-24 | Hewlett-Packard Development Company, L.P. | Raman signal-enhancing structures and Raman spectroscopy systems including such structures |
US8958070B2 (en) * | 2007-05-29 | 2015-02-17 | OptoTrace (SuZhou) Technologies, Inc. | Multi-layer variable micro structure for sensing substance |
US8384892B2 (en) * | 2008-10-03 | 2013-02-26 | Board Of Trustees Of The University Of Illinois | Surface enhanced raman spectroscopy on optical resonator (e.g., photonic crystal) surfaces |
US8953159B2 (en) | 2008-10-03 | 2015-02-10 | The Board Of Trustees Of The University Of Illinois | Surface enhanced raman spectroscopy nanodome biosensors and methods of manufacturing the same |
US9272126B2 (en) | 2011-04-29 | 2016-03-01 | The Board Of Trustees Of The University Of Illinois | Photonic biosensors incorporated into tubing, methods of manufacture and instruments for analyzing the biosensors |
US9274105B2 (en) | 2011-07-13 | 2016-03-01 | Optrotrace (SuZhou) Technologies, Inc. | Analyzing chemical and biological substances using nano-structure based spectral sensing |
US8699019B2 (en) | 2011-07-13 | 2014-04-15 | OptoTrace (SuZhou) Technologies, Inc. | Assuring food safety using nano-structure based spectral sensing |
BR112014010696A2 (pt) | 2011-11-02 | 2017-04-25 | Univ Cape Town | método para identificar uma molécula de analito em uma amostra biológica, sensor para capturar um analito de interesse de uma amostra biológica, e, detector |
US9823246B2 (en) | 2011-12-28 | 2017-11-21 | The Board Of Trustees Of The Leland Stanford Junior University | Fluorescence enhancing plasmonic nanoscopic gold films and assays based thereon |
JP6146898B2 (ja) | 2012-06-29 | 2017-06-14 | 国立研究開発法人物質・材料研究機構 | 表面増強ラマン分光分析用(sers)基板、その製造方法、それを用いたバイオセンサおよびそれを用いたマイクロ流路デバイス |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3926564A (en) * | 1974-02-25 | 1975-12-16 | Gen Electric | Substrate for immunological tests and method of fabrication thereof |
DE2638250C2 (de) * | 1975-08-27 | 1985-11-28 | General Electric Co., Schenectady, N.Y. | Diagnostisches Verfahren zum Bestimmen der Anwesenheit oder Abwesenheit eines spezifischen Proteins in einer biologischen Probe, sowie Vorrichtung zur Durchführung des Verfahrens |
US4267234A (en) * | 1978-03-17 | 1981-05-12 | California Institute Of Technology | Polyglutaraldehyde synthesis and protein bonding substrates |
NL7807532A (nl) * | 1978-07-13 | 1980-01-15 | Akzo Nv | Metaal-immunotest. |
US4267235A (en) * | 1979-03-19 | 1981-05-12 | California Institute Of Technology | Polyglutaraldehyde microspheres |
US4369226A (en) * | 1979-03-19 | 1983-01-18 | California Institute Of Technology | Polyglutaraldehyde synthesis and protein bonding substrates |
US4438239A (en) * | 1981-03-30 | 1984-03-20 | California Institute Of Technology | Microsphere coated substrate containing reactive aldehyde groups |
EP0167834A3 (de) * | 1984-06-08 | 1988-03-09 | Yeda Research And Development Company, Ltd. | Metall enthaltende Polyaldehydmikrokugeln |
DE3568874D1 (en) * | 1984-06-13 | 1989-04-20 | Ares Serono Inc | Photometric instruments, their use in methods of optical analysis, and ancillary devices therefor |
GB8618133D0 (en) * | 1986-07-24 | 1986-09-03 | Pa Consulting Services | Biosensors |
-
1992
- 1992-07-21 JP JP5503029A patent/JPH07500413A/ja active Pending
- 1992-07-21 EP EP92917226A patent/EP0598003B1/de not_active Expired - Lifetime
- 1992-07-21 WO PCT/US1992/006070 patent/WO1993002362A1/en active IP Right Grant
- 1992-07-21 DE DE69228421T patent/DE69228421D1/de not_active Expired - Lifetime
- 1992-07-21 AT AT92917226T patent/ATE176728T1/de not_active IP Right Cessation
-
1995
- 1995-05-30 US US08/453,443 patent/US5527712A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5527712A (en) | 1996-06-18 |
JPH07500413A (ja) | 1995-01-12 |
EP0598003B1 (de) | 1999-02-10 |
EP0598003A1 (de) | 1994-05-25 |
WO1993002362A1 (en) | 1993-02-04 |
DE69228421D1 (de) | 1999-03-25 |
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Legal Events
Date | Code | Title | Description |
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |