ATE328276T1 - Verfahren zur identifizierung von liganden eines biologischen substrats - Google Patents
Verfahren zur identifizierung von liganden eines biologischen substratsInfo
- Publication number
- ATE328276T1 ATE328276T1 AT02705752T AT02705752T ATE328276T1 AT E328276 T1 ATE328276 T1 AT E328276T1 AT 02705752 T AT02705752 T AT 02705752T AT 02705752 T AT02705752 T AT 02705752T AT E328276 T1 ATE328276 T1 AT E328276T1
- Authority
- AT
- Austria
- Prior art keywords
- biological substrate
- identifying ligands
- binding
- compound
- binds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/807—Hapten conjugated with peptide or protein
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/758,916 US6656694B2 (en) | 2001-01-11 | 2001-01-11 | Method for identifying a ligand for a biological substrate |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE328276T1 true ATE328276T1 (de) | 2006-06-15 |
Family
ID=25053626
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02705752T ATE328276T1 (de) | 2001-01-11 | 2002-01-10 | Verfahren zur identifizierung von liganden eines biologischen substrats |
Country Status (7)
Country | Link |
---|---|
US (1) | US6656694B2 (de) |
EP (1) | EP1350108B1 (de) |
JP (1) | JP4111830B2 (de) |
AT (1) | ATE328276T1 (de) |
AU (1) | AU2002239882A1 (de) |
DE (1) | DE60211849T2 (de) |
WO (1) | WO2002056016A2 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020172967A1 (en) * | 2001-02-13 | 2002-11-21 | Gadek Thomas R. | Identification of non-covalent complexes by mass spectrometry |
WO2005007645A1 (en) * | 2003-07-11 | 2005-01-27 | Theravance, Inc. | Substituted 4-amino-1-benzylpiperidine compounds |
WO2005087735A1 (en) * | 2004-03-11 | 2005-09-22 | Theravance, Inc. | Biphenyl compounds useful as muscarinic receptor antagonists |
US7262205B2 (en) | 2004-03-11 | 2007-08-28 | Theravance, Inc. | Biphenyl compounds useful as muscarinic receptor antagonists |
TWI341836B (en) | 2004-03-11 | 2011-05-11 | Theravance Inc | Biphenyl compounds useful as muscarinic receptor antagonists |
US7524962B2 (en) * | 2004-03-11 | 2009-04-28 | Theravance, Inc. | Biphenyl compounds useful as muscarinic receptor antagonists |
WO2005087734A1 (en) * | 2004-03-11 | 2005-09-22 | Theravance, Inc. | Biphenyl compounds useful as muscarinic receptor antagonists |
TW200538095A (en) * | 2004-03-11 | 2005-12-01 | Theravance Inc | Biphenyl compounds useful as muscarinic receptor antagonists |
WO2005087733A1 (en) * | 2004-03-11 | 2005-09-22 | Theravance, Inc. | Biphenyl compounds useful as muscarinic receptor antagonists |
WO2005087737A1 (en) | 2004-03-11 | 2005-09-22 | Theravance, Inc. | Biphenyl compounds useful as muscarinic receptor antagonists |
US20060052943A1 (en) * | 2004-07-28 | 2006-03-09 | Karthik Ramani | Architectures, queries, data stores, and interfaces for proteins and drug molecules |
TW200714587A (en) * | 2005-03-10 | 2007-04-16 | Theravance Inc | Biphenyl compounds useful as muscarinic receptor antagonists |
JP2008533028A (ja) * | 2005-03-10 | 2008-08-21 | セラヴァンス, インコーポレーテッド | ムスカリン性受容体アンタゴニストとして有用なビフェニル化合物 |
WO2006099031A1 (en) * | 2005-03-10 | 2006-09-21 | Theravance, Inc. | Biphenyl compounds useful as muscarinic receptor antagonists |
US7642355B2 (en) * | 2005-03-10 | 2010-01-05 | Theravance, Inc. | Biphenyl compounds useful as muscarinic receptor antagonists |
US7659403B2 (en) * | 2005-03-10 | 2010-02-09 | Theravance, Inc. | Biphenyl compounds useful as muscarinic receptor antagonists |
EP1893577A1 (de) * | 2005-06-13 | 2008-03-05 | Theravance, Inc. | Biphenylverbindungen als muscarinrezeptor-antagonisten |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE92632T1 (de) | 1987-09-30 | 1993-08-15 | Beckman Instruments Inc | Aus zwei verzahnungen bestehendes konjugat und verfahren zu seiner verwendung. |
EP0593956B1 (de) | 1992-10-21 | 2002-02-13 | Dade Behring Inc. | Agglutinationstest unter Anwendung eines multivalenten Liganden |
US5698401A (en) | 1995-11-14 | 1997-12-16 | Abbott Laboratories | Use of nuclear magnetic resonance to identify ligands to target biomolecules |
WO1997035202A1 (en) | 1996-03-21 | 1997-09-25 | Princeton University | Carbohydrate-based ligand library, assay and method |
US6011137A (en) | 1996-04-03 | 2000-01-04 | University Of North Carolina At Chapel Hill | Identification and isolation of novel polypeptides having WW domains and methods of using same |
WO1999025384A2 (en) | 1997-11-17 | 1999-05-27 | University Of Miami | Multimeric tethered ligands and their use in receptor-ligand interactions |
WO1999042476A1 (en) | 1998-02-20 | 1999-08-26 | Advanced Medicine, Inc. | Novel antibacterial agents |
WO1999064032A1 (en) | 1998-06-08 | 1999-12-16 | Advanced Medicine, Inc. | Combinatorial synthesis of multibinding libraries |
US6335155B1 (en) | 1998-06-26 | 2002-01-01 | Sunesis Pharmaceuticals, Inc. | Methods for rapidly identifying small organic molecule ligands for binding to biological target molecules |
-
2001
- 2001-01-11 US US09/758,916 patent/US6656694B2/en not_active Expired - Lifetime
-
2002
- 2002-01-10 AU AU2002239882A patent/AU2002239882A1/en not_active Abandoned
- 2002-01-10 AT AT02705752T patent/ATE328276T1/de not_active IP Right Cessation
- 2002-01-10 JP JP2002556220A patent/JP4111830B2/ja not_active Expired - Lifetime
- 2002-01-10 DE DE60211849T patent/DE60211849T2/de not_active Expired - Lifetime
- 2002-01-10 EP EP02705752A patent/EP1350108B1/de not_active Expired - Lifetime
- 2002-01-10 WO PCT/US2002/000807 patent/WO2002056016A2/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
WO2002056016A3 (en) | 2003-02-06 |
DE60211849D1 (de) | 2006-07-06 |
JP2005501218A (ja) | 2005-01-13 |
EP1350108B1 (de) | 2006-05-31 |
EP1350108A2 (de) | 2003-10-08 |
AU2002239882A1 (en) | 2002-07-24 |
JP4111830B2 (ja) | 2008-07-02 |
DE60211849T2 (de) | 2006-11-23 |
WO2002056016A2 (en) | 2002-07-18 |
US20020090645A1 (en) | 2002-07-11 |
US6656694B2 (en) | 2003-12-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |