ATE175234T1 - Geflügelspezifischen immunglobulin g produzierende hybridomas - Google Patents

Geflügelspezifischen immunglobulin g produzierende hybridomas

Info

Publication number
ATE175234T1
ATE175234T1 AT91912328T AT91912328T ATE175234T1 AT E175234 T1 ATE175234 T1 AT E175234T1 AT 91912328 T AT91912328 T AT 91912328T AT 91912328 T AT91912328 T AT 91912328T AT E175234 T1 ATE175234 T1 AT E175234T1
Authority
AT
Austria
Prior art keywords
cell
avian
fused
igg
producing
Prior art date
Application number
AT91912328T
Other languages
English (en)
Inventor
Haruo Matsuda
Shigeyuki Nishinaka
Takashi Suzuki
Original Assignee
Nippon Kokan Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Kokan Kk filed Critical Nippon Kokan Kk
Application granted granted Critical
Publication of ATE175234T1 publication Critical patent/ATE175234T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT91912328T 1990-07-10 1991-07-10 Geflügelspezifischen immunglobulin g produzierende hybridomas ATE175234T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18217490 1990-07-10

Publications (1)

Publication Number Publication Date
ATE175234T1 true ATE175234T1 (de) 1999-01-15

Family

ID=16113640

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91912328T ATE175234T1 (de) 1990-07-10 1991-07-10 Geflügelspezifischen immunglobulin g produzierende hybridomas

Country Status (7)

Country Link
US (1) US5411881A (de)
EP (1) EP0491057B1 (de)
AT (1) ATE175234T1 (de)
AU (1) AU8212291A (de)
CA (1) CA2066433A1 (de)
DE (1) DE69130702T2 (de)
WO (1) WO1992001043A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0539970B1 (de) * 1991-10-30 1999-05-26 Idemitsu Kosan Company Limited Verfahren zur Herstellung von menschlichen Lymphozyten und menschlichen Antikörpern; und so hergestellte Antikörper
CA2146816A1 (en) 1994-04-22 1995-10-23 Joachim E. Klee Process and composition for preparing a dental polymer product
EP0737743A1 (de) * 1995-04-14 1996-10-16 Nkk Corporation Thymidin-Kinase-Mangeldes Oxabain-beständiges Kükenhybridoma
US6451984B1 (en) * 1995-09-08 2002-09-17 The United States Of America As Represented By The Secretary Of Agriculture Chicken monoclonal antibodies specific for coccidial antigens involved in invasion of host lymphocytes
WO1997016537A1 (en) * 1995-10-30 1997-05-09 Spectral Diagnostics, Inc. Stable chicken b-cell line and method of use thereof
US6143559A (en) 1996-11-18 2000-11-07 Arch Development Corporation Methods for the production of chicken monoclonal antibodies
CU22731A1 (es) * 1998-02-05 2002-02-28 Centro Inmunologia Molecular Anticuerpo monoclonal que reconoce el oligosacárido ácido siálico n´glicolilado-galactosa-glucosa (ngcneu-gal-glu) en tumores malignos y composiciones farmacéuticas que los contienen
WO2002012437A2 (en) 2000-08-03 2002-02-14 Schooten Wim Van Production of humanized antibodies in transgenic animals
CN1852925A (zh) 2003-07-15 2006-10-25 人类多克隆治疗公司 人源化免疫球蛋白基因座
US20090053210A1 (en) 2006-09-01 2009-02-26 Roland Buelow Enhanced expression of human or humanized immunoglobulin in non-human transgenic animals
KR102096731B1 (ko) 2007-06-01 2020-04-02 오픈 모노클로날 테크놀로지, 인코포레이티드 내생적 면역글로불린 유전자를 억제하고 트랜스제닉 인간 이디오타입 항체를 생산하기 위한 방법 및 조성물
EP3960865A1 (de) 2010-08-02 2022-03-02 Regeneron Pharmaceuticals, Inc. Mäuse, die bindeproteine mit vl-domänen produzieren
EP4269602A3 (de) 2012-12-14 2023-12-27 OmniAB, Inc. Polynukleotide zur codierung von nagerantikörpern mit menschlichen idiotypen und tiere damit
BR112016021679A2 (pt) 2014-03-21 2018-12-04 Regeneron Pharmaceuticals, Inc. proteína de ligação ao antígeno, métodos de produção de uma proteína de ligação ao antígeno e de identificação de uma ou mais proteínas de ligação ao antígeno, hibridoma, ácido nucleico, célula, e, animal não humano geneticamente modificado.
SG10201808225TA (en) 2014-03-21 2018-10-30 Regeneron Pharma Non-human animals that make single domain binding proteins
HK1250038A1 (zh) 2015-03-19 2018-11-23 瑞泽恩制药公司 选择结合抗原的轻链可变区的非人动物
SG10202109874VA (en) 2017-01-19 2021-10-28 Open Monoclonal Tech Inc Human antibodies from transgenic rodents with multiple heavy chain immunoglobulin loci
US20210000088A1 (en) 2018-03-21 2021-01-07 Crystal Bioscience Inc. Transgenic chicken that produces human antibodies
US12543710B2 (en) 2018-06-08 2026-02-10 Crystal Bioscience Inc. Transgenic animal for producing diversified antibodies that have the same light chain II
KR20210021024A (ko) 2018-06-13 2021-02-24 크리스탈 바이오사이언스 주식회사 유전자 변환에 의한 자율 중쇄 가변 도메인의 수정에 의한 항체 생산
JP7515410B2 (ja) 2018-06-13 2024-07-12 クリスタル バイオサイエンス インコーポレイテッド 複数のジスルフィド架橋によって安定化され、遺伝子変換によって多様化された長いｃｄｒ－ｈ３ｓで抗体を作製するトランスジェニックニワトリ
US12467062B2 (en) 2018-12-21 2025-11-11 Compass Therapeutics Llc Transgenic mouse expressing common human light chain
TW202430641A (zh) 2023-01-18 2024-08-01 美商基利科學股份有限公司 人類免疫球蛋白二元輕鏈轉殖基因構築體及其用途
TW202430558A (zh) 2023-01-18 2024-08-01 美商基利科學股份有限公司 人類免疫球蛋白重鏈長cdr3轉殖基因構築體及其用途
TWI897189B (zh) 2023-01-18 2025-09-11 美商基利科學股份有限公司 具有經改變重鏈基因座之嵌合基因轉殖免疫球蛋白小鼠及其製造及使用方法
WO2026019824A1 (en) 2024-07-16 2026-01-22 Gilead Sciences, Inc. Human immunoglobulin common light chain transgene constructs and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63270699A (ja) * 1987-04-28 1988-11-08 Konica Corp モノクロ−ナル抗体
JPH0722518B2 (ja) * 1987-06-04 1995-03-15 コニカ株式会社 モノクローナル抗体
JPH02186980A (ja) * 1989-01-12 1990-07-23 Nkk Corp ニワトリチミジンキナーゼ欠損ｂリンパ芽細胞株

Also Published As

Publication number Publication date
EP0491057A1 (de) 1992-06-24
AU8212291A (en) 1992-02-04
DE69130702T2 (de) 1999-05-27
CA2066433A1 (en) 1992-01-11
US5411881A (en) 1995-05-02
WO1992001043A1 (en) 1992-01-23
EP0491057A4 (en) 1993-05-26
DE69130702D1 (de) 1999-02-11
EP0491057B1 (de) 1998-12-30

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