ATE167232T1 - Protein mit knochenbildungs-eigenschaften und verfahren zu seiner herstellung - Google Patents

Protein mit knochenbildungs-eigenschaften und verfahren zu seiner herstellung

Info

Publication number
ATE167232T1
ATE167232T1 AT93104650T AT93104650T ATE167232T1 AT E167232 T1 ATE167232 T1 AT E167232T1 AT 93104650 T AT93104650 T AT 93104650T AT 93104650 T AT93104650 T AT 93104650T AT E167232 T1 ATE167232 T1 AT E167232T1
Authority
AT
Austria
Prior art keywords
production
bone
protein
forming properties
osf
Prior art date
Application number
AT93104650T
Other languages
English (en)
Inventor
Egon Dr Amann
Yoko Otawara-Hamamoto
Reiko Kikuno
Sunao Takeshita
Kenichi Tezuka
Original Assignee
Hoechst Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Japan filed Critical Hoechst Japan
Application granted granted Critical
Publication of ATE167232T1 publication Critical patent/ATE167232T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT93104650T 1992-03-27 1993-03-22 Protein mit knochenbildungs-eigenschaften und verfahren zu seiner herstellung ATE167232T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4071501A JPH05268982A (ja) 1992-03-27 1992-03-27 骨形成作用を有する新規な蛋白質およびその製造法

Publications (1)

Publication Number Publication Date
ATE167232T1 true ATE167232T1 (de) 1998-06-15

Family

ID=13462492

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93104650T ATE167232T1 (de) 1992-03-27 1993-03-22 Protein mit knochenbildungs-eigenschaften und verfahren zu seiner herstellung

Country Status (9)

Country Link
US (1) US5756664A (de)
EP (1) EP0562508B1 (de)
JP (1) JPH05268982A (de)
AT (1) ATE167232T1 (de)
CA (1) CA2092768A1 (de)
DE (1) DE69319012T2 (de)
DK (1) DK0562508T3 (de)
ES (1) ES2123582T3 (de)
GR (1) GR3027671T3 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0725799A1 (de) * 1993-10-29 1996-08-14 Dana-Farber Cancer Institute, Inc. Tumormarker und verfahren zur seiner isolierung
SE520392C2 (sv) 1996-09-27 2003-07-01 Creative Peptides Sweden Ab C Specifika peptider för behandling av diabetes mellitus
US6518063B1 (en) 1997-05-29 2003-02-11 Board Of Regents, The University Of Texas System Osf2/Cbfa1 nucleic acids and methods of use therefor
EP1524524A1 (de) * 1998-12-18 2005-04-20 Scios Inc. Methode zur Detektion und Verwendung von differentiel exprimiertem OSF-2 in der Diagnose von Herzhypertrophie
AU2001233318A1 (en) * 2000-02-03 2001-08-14 Gene Logic, Inc. Modulation of osf-2 in inflammatory and renal diseases
JP4534092B2 (ja) * 2000-09-08 2010-09-01 第一三共株式会社 心不全治療剤
JP2005500059A (ja) * 2001-08-13 2005-01-06 ダナ−ファーバー キャンサー インスティテュート インク． ペリオスチンに基づく診断アッセイ法
CN100348277C (zh) * 2005-08-09 2007-11-14 中国人民解放军第三军医大学 成骨细胞特异性转录因子－2基因修饰的组织工程化骨的构建方法
RU2008130898A (ru) 2005-12-28 2010-02-10 Асубио Фарма Ко., Лтд. (Jp) Антитело против периостина и содержащая его фармацевтическая композиция для профилактики или лечения заболевания, в развитии которого участвует периостин
US8017119B2 (en) 2005-12-28 2011-09-13 Daiichi Sankyo Company, Ltd. Antibody against periostin, and a pharmaceutical composition comprising it for preventing or treating a disease in which periostin is involved
EP2168599B1 (de) 2007-06-27 2016-08-10 Osaka University Krebsheilmittel mit einem antikörper gegen ein vom exon-17-bereich von periostin kodiertes peptid
NZ601815A (en) * 2008-03-31 2014-10-31 Genentech Inc Compositions and methods for treating and diagnosing asthma
EP2295599B1 (de) * 2008-06-05 2013-07-31 Saga University Verfahren für den nachweis von idiopathischer interstitieller pneumonie
JP2012012344A (ja) * 2010-07-01 2012-01-19 Japan Health Science Foundation 創傷治癒剤
KR101615420B1 (ko) 2010-12-16 2016-04-26 제넨테크, 인크. Th2 억제에 관한 진단 및 치료
WO2013035799A1 (ja) 2011-09-06 2013-03-14 株式会社シノテスト ペリオスチンの特定領域に結合する抗体及びこれを用いたペリオスチンの測定方法
US10227396B2 (en) 2013-03-08 2019-03-12 Osaka University Antibody against peptide encoded by Exon-21 of periostin and pharmaceutical composition for preventing or treating inflammation-associated diseases containing the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8078491A (en) * 1990-06-29 1992-01-23 Hoechst Japan Limited Novel protein capable of causing differential growth of cell and production thereof by genetic engineering technology
JPH09200324A (ja) * 1996-01-12 1997-07-31 Ricoh Co Ltd ファクシミリ装置

Also Published As

Publication number Publication date
US5756664A (en) 1998-05-26
DK0562508T3 (da) 1999-03-29
EP0562508B1 (de) 1998-06-10
DE69319012T2 (de) 1998-12-17
ES2123582T3 (es) 1999-01-16
CA2092768A1 (en) 1993-09-28
EP0562508A2 (de) 1993-09-29
JPH05268982A (ja) 1993-10-19
EP0562508A3 (en) 1994-06-22
GR3027671T3 (en) 1998-11-30
DE69319012D1 (de) 1998-07-16

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