ATE166046T1 - Cyclohexanderivate als kaliumkanalaktivatoren - Google Patents

Cyclohexanderivate als kaliumkanalaktivatoren

Info

Publication number
ATE166046T1
ATE166046T1 AT94114467T AT94114467T ATE166046T1 AT E166046 T1 ATE166046 T1 AT E166046T1 AT 94114467 T AT94114467 T AT 94114467T AT 94114467 T AT94114467 T AT 94114467T AT E166046 T1 ATE166046 T1 AT E166046T1
Authority
AT
Austria
Prior art keywords
potassium channel
channel activators
cyclohexane derivatives
chem
optionally substituted
Prior art date
Application number
AT94114467T
Other languages
English (en)
Inventor
Yasuhiro Kabasawa
Fumihiro Ozaki
Keiji Ishibashi
Takashi Hasegawa
Hitoshi Oinuma
Manabu Shirato
Katsuhiro Moriya
Toshiaki Ogawa
Satoshi Katayama
Shigeru Souda
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Application granted granted Critical
Publication of ATE166046T1 publication Critical patent/ATE166046T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
AT94114467T 1993-09-21 1994-09-14 Cyclohexanderivate als kaliumkanalaktivatoren ATE166046T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP23453893 1993-09-21

Publications (1)

Publication Number Publication Date
ATE166046T1 true ATE166046T1 (de) 1998-05-15

Family

ID=16972600

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94114467T ATE166046T1 (de) 1993-09-21 1994-09-14 Cyclohexanderivate als kaliumkanalaktivatoren

Country Status (14)

Country Link
US (2) US5478839A (de)
EP (1) EP0644182B1 (de)
KR (1) KR0149066B1 (de)
CN (1) CN1100031C (de)
AT (1) ATE166046T1 (de)
AU (1) AU686642B2 (de)
CA (1) CA2131749A1 (de)
DE (1) DE69410198T2 (de)
FI (1) FI107155B (de)
HU (1) HU221198B1 (de)
NO (1) NO302234B1 (de)
NZ (1) NZ264480A (de)
RU (1) RU2129113C1 (de)
ZA (1) ZA947146B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999041246A1 (en) * 1998-02-11 1999-08-19 Du Pont Pharmaceuticals Company Novel cyclic sulfonamide derivatives as metalloproteinase inhibitors
JP4838537B2 (ja) * 2005-05-25 2011-12-14 株式会社 資生堂 不全角化抑制剤、毛穴縮小剤又は肌荒れ防止・改善剤及び皮膚外用組成物
EP2089389A2 (de) 2006-11-01 2009-08-19 Bristol-Myers Squibb Company Heterocyclische verbindungen als modulatoren der glucocorticoidrezeptor,- ap1- und/oder nf-kappa-b-aktivität

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200640A (en) * 1976-04-02 1980-04-29 Chugai Seiyaku Kabushiki Kaisha Nitric ester of N-(2-hydroxyethyl)nicotinamide and pharmaceutical use
GB9000342D0 (en) * 1990-01-08 1990-03-07 May & Baker Ltd New compositions of matter
GB9002879D0 (en) * 1990-02-08 1990-04-04 May & Baker Ltd New compositions of matter
US5444066A (en) * 1991-10-14 1995-08-22 Eisai Co., Ltd. Thioformamide derivatives having hypotensive activity

Also Published As

Publication number Publication date
AU686642B2 (en) 1998-02-12
RU94033470A (ru) 1996-08-10
AU7169694A (en) 1995-04-06
US5478839A (en) 1995-12-26
RU2129113C1 (ru) 1999-04-20
DE69410198T2 (de) 1999-03-11
HU221198B1 (en) 2002-08-28
NO943472L (no) 1995-03-22
EP0644182A1 (de) 1995-03-22
FI107155B (fi) 2001-06-15
DE69410198D1 (de) 1998-06-18
US5605907A (en) 1997-02-25
EP0644182B1 (de) 1998-05-13
FI944207A (fi) 1995-03-22
CN1106380A (zh) 1995-08-09
KR950008446A (ko) 1995-04-17
ZA947146B (en) 1996-03-15
NO943472D0 (no) 1994-09-19
NZ264480A (en) 1995-07-26
CN1100031C (zh) 2003-01-29
NO302234B1 (no) 1998-02-09
FI944207A0 (fi) 1994-09-12
CA2131749A1 (en) 1995-03-22
HU9402702D0 (en) 1994-12-28
KR0149066B1 (ko) 1998-10-15
HUT68036A (en) 1995-05-29

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties