ATE161271T1 - Peptide als lungensurfactant und therapeutisch wirksame mischungen - Google Patents

Peptide als lungensurfactant und therapeutisch wirksame mischungen

Info

Publication number
ATE161271T1
ATE161271T1 AT93916906T AT93916906T ATE161271T1 AT E161271 T1 ATE161271 T1 AT E161271T1 AT 93916906 T AT93916906 T AT 93916906T AT 93916906 T AT93916906 T AT 93916906T AT E161271 T1 ATE161271 T1 AT E161271T1
Authority
AT
Austria
Prior art keywords
peptides
therapeutically effective
lung surfactants
effective mixtures
mixtures
Prior art date
Application number
AT93916906T
Other languages
English (en)
Inventor
Larry R Mclean
J Vincent Edwards
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Application granted granted Critical
Publication of ATE161271T1 publication Critical patent/ATE161271T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1021—Tetrapeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C07K5/06095—Arg-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0819—Tripeptides with the first amino acid being acidic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
AT93916906T 1992-07-29 1993-07-01 Peptide als lungensurfactant und therapeutisch wirksame mischungen ATE161271T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92227992A 1992-07-29 1992-07-29
US7780193A 1993-06-21 1993-06-21

Publications (1)

Publication Number Publication Date
ATE161271T1 true ATE161271T1 (de) 1998-01-15

Family

ID=26759683

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93916906T ATE161271T1 (de) 1992-07-29 1993-07-01 Peptide als lungensurfactant und therapeutisch wirksame mischungen

Country Status (12)

Country Link
US (1) US5861481A (de)
EP (1) EP0656902B1 (de)
JP (1) JPH07509714A (de)
KR (1) KR100279540B1 (de)
AT (1) ATE161271T1 (de)
AU (1) AU671850B2 (de)
DE (1) DE69315849T2 (de)
ES (1) ES2114061T3 (de)
IL (1) IL106476A0 (de)
MX (1) MX9304540A (de)
NZ (1) NZ254503A (de)
WO (1) WO1994003485A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO161196A0 (en) * 1996-08-13 1996-09-05 Commonwealth Scientific And Industrial Research Organisation Novel compounds
US6660833B1 (en) * 2000-02-29 2003-12-09 Harbor-Ucla Research And Education Institute Respiratory distress syndrome therapy with peptide analogs of human SP-B
CA2654008C (en) * 2006-06-01 2015-11-24 Therapeutic Peptides, Inc. Polymeric biosurfactants
US20100284969A1 (en) * 2007-06-05 2010-11-11 Frank Guarnieri Methods and Compositions for Delivery of Medicaments to the Lungs
EP2331048B1 (de) * 2008-05-29 2019-07-10 Donald Owen Oligomere biotenside
US9289388B2 (en) 2008-12-10 2016-03-22 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of medicaments to the lungs
US10836791B2 (en) * 2016-09-15 2020-11-17 Dsm Ip Assets B.V. Compounds
CN111568853B (zh) * 2020-04-30 2023-07-28 杭州濡湜生物科技有限公司 一种新型肺部智能释药系统

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861756A (en) * 1988-03-08 1989-08-29 Merrell Dow Pharmaceuticals Inc. Synthetic pulmonary surfactant
AR245141A1 (es) * 1988-07-01 1993-12-30 Merrell Dow Pharma Procedimiento de sintesis secuencial o de bloques en fase solida para preparar polipeptidos de estructura helicoidal.
AU655831B2 (en) * 1991-08-22 1995-01-12 Merrell Pharmaceuticals Inc. Novel orally-active elastase inhibitors

Also Published As

Publication number Publication date
MX9304540A (es) 1994-02-28
WO1994003485A1 (en) 1994-02-17
AU4660793A (en) 1994-03-03
JPH07509714A (ja) 1995-10-26
NZ254503A (en) 1996-08-27
DE69315849T2 (de) 1998-05-14
EP0656902B1 (de) 1997-12-17
US5861481A (en) 1999-01-19
IL106476A0 (en) 1993-11-15
AU671850B2 (en) 1996-09-12
KR100279540B1 (ko) 2001-02-01
DE69315849D1 (de) 1998-01-29
EP0656902A1 (de) 1995-06-14
ES2114061T3 (es) 1998-05-16
KR950702574A (ko) 1995-07-29

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee