ATE157671T1 - Synthetische peptide als lungensurfactants mit kovalent gebundenen antioxidantien - Google Patents
Synthetische peptide als lungensurfactants mit kovalent gebundenen antioxidantienInfo
- Publication number
- ATE157671T1 ATE157671T1 AT93916889T AT93916889T ATE157671T1 AT E157671 T1 ATE157671 T1 AT E157671T1 AT 93916889 T AT93916889 T AT 93916889T AT 93916889 T AT93916889 T AT 93916889T AT E157671 T1 ATE157671 T1 AT E157671T1
- Authority
- AT
- Austria
- Prior art keywords
- covalently bonded
- synthetic peptides
- lung surfactants
- surfactants
- antioxidants
- Prior art date
Links
- 239000003580 lung surfactant Substances 0.000 title abstract 3
- 239000003963 antioxidant agent Substances 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 229940066294 lung surfactant Drugs 0.000 title 1
- 230000003078 antioxidant effect Effects 0.000 abstract 2
- 150000002632 lipids Chemical class 0.000 abstract 2
- 206010001052 Acute respiratory distress syndrome Diseases 0.000 abstract 1
- 208000013616 Respiratory Distress Syndrome Diseases 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Anti-Oxidant Or Stabilizer Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92309292A | 1992-07-31 | 1992-07-31 | |
| US7780293A | 1993-06-21 | 1993-06-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE157671T1 true ATE157671T1 (de) | 1997-09-15 |
Family
ID=26759685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93916889T ATE157671T1 (de) | 1992-07-31 | 1993-06-30 | Synthetische peptide als lungensurfactants mit kovalent gebundenen antioxidantien |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US5623052A (de) |
| EP (1) | EP0652894B1 (de) |
| JP (1) | JPH07509713A (de) |
| KR (1) | KR100279059B1 (de) |
| AT (1) | ATE157671T1 (de) |
| AU (1) | AU664112B2 (de) |
| CA (1) | CA2137348C (de) |
| DE (1) | DE69313647T2 (de) |
| ES (1) | ES2107048T3 (de) |
| IL (1) | IL106503A0 (de) |
| MX (1) | MX9304621A (de) |
| NZ (1) | NZ254496A (de) |
| WO (1) | WO1994003484A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE157671T1 (de) * | 1992-07-31 | 1997-09-15 | Merrell Pharma Inc | Synthetische peptide als lungensurfactants mit kovalent gebundenen antioxidantien |
| WO2000005250A1 (en) | 1998-07-23 | 2000-02-03 | Yeda Research And Development Co., Ltd | Treatment of autoimmune conditions with copolymer 1 and related copolymers and peptides |
| ES2527760T3 (es) | 1998-07-23 | 2015-01-29 | Yeda Research And Development Co., Ltd. | Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos |
| US6800287B2 (en) | 1998-09-25 | 2004-10-05 | Yeda Research And Development Co., Ltd. | Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use |
| ZA200206457B (en) | 2000-02-18 | 2003-08-13 | Yeda Res & Dev | Oral, nasal and pulmonary dosage formulations of copolymer 1. |
| US20020077278A1 (en) | 2000-06-05 | 2002-06-20 | Yong V. Wee | Use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders |
| WO2002076503A1 (en) * | 2000-06-20 | 2002-10-03 | Mayo Foundation For Medical Education And Research | Treatment of central nervous system diseases by antibodies against glatiramer acetate |
| AU2001283047A1 (en) | 2000-07-31 | 2002-02-13 | World Resources Corporation | Plant derived antioxidants |
| US6465432B1 (en) | 2000-08-28 | 2002-10-15 | Kraft Food Holdings, Inc. | Isolated antioxidant peptides form casein and methods for preparing, isolating, and identifying antioxidant peptides |
| KR100657048B1 (ko) | 2001-12-04 | 2006-12-12 | 테바 파마슈티컬 인더스트리즈 리미티드 | 글라티라머 아세테이트의 효능 측정 방법 |
| MXPA04010560A (es) * | 2002-04-25 | 2005-08-15 | Scripps Research Inst | Tratamiento y prevencion de condiciones pulmonares. |
| EP1809272A4 (de) * | 2004-10-18 | 2008-01-02 | Maroon Biotech Corp | Verfahren und zusammensetzungen zur behandlung von schäden durch freie radikale |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4861756A (en) * | 1988-03-08 | 1989-08-29 | Merrell Dow Pharmaceuticals Inc. | Synthetic pulmonary surfactant |
| NZ229737A (en) * | 1988-07-01 | 1991-05-28 | Merrell Dow Pharma | Polypeptides and derivatives of them with lung surfactant properties and their preparation |
| FR2676056B1 (fr) * | 1991-05-03 | 1993-07-16 | Adir | Nouveaux derives du benzopyranne leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| ZA926185B (en) * | 1991-08-22 | 1993-03-01 | Merrell Dow Pharma | Novel orally-active elastase inhibitors. |
| US5272252A (en) * | 1991-11-04 | 1993-12-21 | Merrell Dow Pharmaceuticals Inc. | Synthetic lung surfactant having antioxidant properties |
| ATE157671T1 (de) * | 1992-07-31 | 1997-09-15 | Merrell Pharma Inc | Synthetische peptide als lungensurfactants mit kovalent gebundenen antioxidantien |
-
1993
- 1993-06-30 AT AT93916889T patent/ATE157671T1/de not_active IP Right Cessation
- 1993-06-30 NZ NZ254496A patent/NZ254496A/en unknown
- 1993-06-30 KR KR1019950700355A patent/KR100279059B1/ko not_active Expired - Fee Related
- 1993-06-30 JP JP6505301A patent/JPH07509713A/ja not_active Ceased
- 1993-06-30 WO PCT/US1993/006249 patent/WO1994003484A1/en not_active Ceased
- 1993-06-30 AU AU46596/93A patent/AU664112B2/en not_active Ceased
- 1993-06-30 EP EP93916889A patent/EP0652894B1/de not_active Expired - Lifetime
- 1993-06-30 CA CA002137348A patent/CA2137348C/en not_active Expired - Fee Related
- 1993-06-30 ES ES93916889T patent/ES2107048T3/es not_active Expired - Lifetime
- 1993-06-30 DE DE69313647T patent/DE69313647T2/de not_active Expired - Fee Related
- 1993-07-28 IL IL106503A patent/IL106503A0/xx unknown
- 1993-07-30 MX MX9304621A patent/MX9304621A/es unknown
-
1995
- 1995-07-14 US US08/502,722 patent/US5623052A/en not_active Expired - Fee Related
-
1996
- 1996-12-26 US US08/772,239 patent/US5886156A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| MX9304621A (es) | 1994-02-28 |
| US5886156A (en) | 1999-03-23 |
| NZ254496A (en) | 1996-08-27 |
| KR950702573A (ko) | 1995-07-29 |
| ES2107048T3 (es) | 1997-11-16 |
| WO1994003484A1 (en) | 1994-02-17 |
| CA2137348C (en) | 2000-11-28 |
| EP0652894B1 (de) | 1997-09-03 |
| KR100279059B1 (ko) | 2001-01-15 |
| AU664112B2 (en) | 1995-11-02 |
| CA2137348A1 (en) | 1994-02-17 |
| DE69313647T2 (de) | 1998-03-12 |
| EP0652894A1 (de) | 1995-05-17 |
| JPH07509713A (ja) | 1995-10-26 |
| AU4659693A (en) | 1994-03-03 |
| DE69313647D1 (de) | 1997-10-09 |
| IL106503A0 (en) | 1993-11-15 |
| US5623052A (en) | 1997-04-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |