ATE154758T1 - Levobupivacain nützlich zur behandlung von chronischen schmerzen - Google Patents
Levobupivacain nützlich zur behandlung von chronischen schmerzenInfo
- Publication number
- ATE154758T1 ATE154758T1 AT94929595T AT94929595T ATE154758T1 AT E154758 T1 ATE154758 T1 AT E154758T1 AT 94929595 T AT94929595 T AT 94929595T AT 94929595 T AT94929595 T AT 94929595T AT E154758 T1 ATE154758 T1 AT E154758T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- chronic pain
- levobupivacain
- useful
- treating chronic
- Prior art date
Links
- 208000002193 Pain Diseases 0.000 title abstract 3
- 208000000094 Chronic Pain Diseases 0.000 title abstract 2
- LEBVLXFERQHONN-INIZCTEOSA-N levobupivacaine Chemical compound CCCCN1CCCC[C@H]1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-INIZCTEOSA-N 0.000 abstract 2
- 229960004288 levobupivacaine Drugs 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 230000001010 compromised effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939321061A GB9321061D0 (en) | 1993-10-13 | 1993-10-13 | Analgestic agent and its use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE154758T1 true ATE154758T1 (de) | 1997-07-15 |
Family
ID=10743430
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94929595T ATE154758T1 (de) | 1993-10-13 | 1994-10-13 | Levobupivacain nützlich zur behandlung von chronischen schmerzen |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5955479A (de) |
| EP (1) | EP0723444B1 (de) |
| JP (1) | JPH09503777A (de) |
| KR (1) | KR100343314B1 (de) |
| CN (1) | CN1074919C (de) |
| AT (1) | ATE154758T1 (de) |
| AU (1) | AU692477B2 (de) |
| CA (1) | CA2173208C (de) |
| DE (1) | DE69403969T2 (de) |
| DK (1) | DK0723444T3 (de) |
| ES (1) | ES2105766T3 (de) |
| GB (1) | GB9321061D0 (de) |
| GR (1) | GR3024787T3 (de) |
| HK (1) | HK1006421A1 (de) |
| NO (1) | NO309304B1 (de) |
| WO (1) | WO1995010276A1 (de) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2201179T3 (es) * | 1995-04-13 | 2004-03-16 | Darwin Discovery Limited | Levobupivacaina y su utilizacion coo analgesico en mujeres embarazadas. |
| GB9704349D0 (en) * | 1997-03-03 | 1997-04-23 | Chiroscience Ltd | Levobupivacaine and its use |
| GB9704352D0 (en) * | 1997-03-03 | 1997-04-23 | Chiroscience Ltd | Levobupivacaine and its use |
| GB9704370D0 (en) * | 1997-03-03 | 1997-04-23 | Chiroscience Ltd | Levobupivacaine and its use |
| SK187899A3 (en) * | 1997-07-21 | 2000-12-11 | Astra Ab | Compositions, kits, and methods for inhibiting cerebral neurovascular disorders and muscular headaches |
| US6432986B2 (en) | 1997-07-21 | 2002-08-13 | Bruce H. Levin | Compositions, kits, and methods for inhibiting cerebral neurovascular disorders and muscular headaches |
| US7799337B2 (en) | 1997-07-21 | 2010-09-21 | Levin Bruce H | Method for directed intranasal administration of a composition |
| ES2198731T3 (es) * | 1997-07-22 | 2004-02-01 | Darwin Discovery Limited | Utilizacion de levobupivacaina. |
| NZ503513A (en) | 1997-09-18 | 2004-12-24 | Skyepharma Inc | Sustained-release liposomal anesthetic compositions |
| US20020039596A1 (en) | 1997-11-14 | 2002-04-04 | Hartoun Hartounian | Production of multivesicular liposomes |
| DK1032390T3 (da) * | 1997-11-19 | 2004-03-15 | Darwin Discovery Ltd | Anæstetisk formulering |
| AU752225B2 (en) | 1998-07-17 | 2002-09-12 | Pacira Pharmaceuticals, Inc. | Biodegradable compositions for the controlled release of encapsulated substances |
| BR0002246A (pt) | 2000-04-06 | 2003-04-15 | Cristalia Prod Quimicos Farm | Processo de obtenção dos enantiÈmeros da bupivacaìna racêmica, processo de obtenção de composições farmacêuticas a base de levobupivacaìna: composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis e utilização das composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis |
| EP1395243A2 (de) * | 2001-05-31 | 2004-03-10 | SkyePharma Inc. | Verkapselung von nanosuspensionen in liposomen und mikrosphärulen |
| JP2005519873A (ja) | 2001-11-14 | 2005-07-07 | アルザ・コーポレーション | カテーテル注入可能なデポー組成物およびそれらの使用 |
| US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
| ES2319400T3 (es) | 2002-07-31 | 2009-05-07 | Durect Corporation | Composiciones deposito inyectables y empleo de las mismas. |
| EP2030611A1 (de) | 2002-07-31 | 2009-03-04 | Alza Corporation | Injizierbare multimodale Polymerablagerungszusammensetzungen und Verwendungen damit |
| US8337883B2 (en) | 2006-11-03 | 2012-12-25 | Durect Corporation | Transdermal delivery systems |
| DE102008037682A1 (de) * | 2008-08-14 | 2010-04-08 | Strackharn, Klaus, Dr.med. | Verwendung äquipotenter Dosierungen von Lokalanästetika oder Derivaten davon zur Therapie chronischer Schmerzen |
| CN105764491A (zh) | 2013-12-09 | 2016-07-13 | 度瑞公司 | 药物活性剂复合物、聚合物复合物，以及包括其的组合物和方法 |
| JP2020503324A (ja) * | 2016-12-26 | 2020-01-30 | セリックス バイオ プライヴェート リミテッドＣｅｌｌｉｘ Ｂｉｏ Ｐｒｉｖａｔｅ Ｌｉｍｉｔｅｄ | 慢性疼痛の処置のための組成物及び方法 |
| US11357727B1 (en) | 2021-01-22 | 2022-06-14 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US11033495B1 (en) | 2021-01-22 | 2021-06-15 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US11278494B1 (en) | 2021-01-22 | 2022-03-22 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US12151024B2 (en) | 2021-01-22 | 2024-11-26 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| CN117979970A (zh) | 2021-10-14 | 2024-05-03 | 帕西拉制药有限公司 | 布比卡因多囊脂质体制剂及其用途 |
| KR20250047226A (ko) | 2022-05-05 | 2025-04-03 | 피에프오에프 엘엘씨 | 마취 신경 블록 및 방법 |
| US12070454B1 (en) | 2022-05-05 | 2024-08-27 | Pfof Llc | Anesthetic nerve block and method |
| US12251472B1 (en) | 2024-05-20 | 2025-03-18 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US12280149B1 (en) | 2024-05-20 | 2025-04-22 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US12156940B1 (en) | 2024-05-20 | 2024-12-03 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4695576A (en) * | 1984-07-09 | 1987-09-22 | Astra Lake Medel Aktiebolag | L-N-n-propylpipecolic acid-2,6-xylidide |
| ES2101578T3 (es) * | 1993-10-13 | 1997-07-01 | Chiroscience Ltd | Agente analgesico y su utilizacion. |
| ITTO20010597A1 (it) * | 2001-06-20 | 2002-12-20 | Plaset Spa | Pompa per liquidi, in particolare pompa centrifuga per apparecchi elettrodomestici. |
-
1993
- 1993-10-13 GB GB939321061A patent/GB9321061D0/en active Pending
-
1994
- 1994-10-13 KR KR1019960701863A patent/KR100343314B1/ko not_active Expired - Lifetime
- 1994-10-13 EP EP94929595A patent/EP0723444B1/de not_active Expired - Lifetime
- 1994-10-13 WO PCT/GB1994/002248 patent/WO1995010276A1/en not_active Ceased
- 1994-10-13 CA CA002173208A patent/CA2173208C/en not_active Expired - Lifetime
- 1994-10-13 AU AU78593/94A patent/AU692477B2/en not_active Expired
- 1994-10-13 JP JP7511488A patent/JPH09503777A/ja active Pending
- 1994-10-13 AT AT94929595T patent/ATE154758T1/de active
- 1994-10-13 DE DE69403969T patent/DE69403969T2/de not_active Expired - Lifetime
- 1994-10-13 US US08/628,689 patent/US5955479A/en not_active Expired - Lifetime
- 1994-10-13 ES ES94929595T patent/ES2105766T3/es not_active Expired - Lifetime
- 1994-10-13 HK HK98105742A patent/HK1006421A1/en not_active IP Right Cessation
- 1994-10-13 CN CN94193775A patent/CN1074919C/zh not_active Expired - Lifetime
- 1994-10-13 DK DK94929595.0T patent/DK0723444T3/da active
-
1996
- 1996-04-12 NO NO961478A patent/NO309304B1/no not_active IP Right Cessation
-
1997
- 1997-09-17 GR GR970402411T patent/GR3024787T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1133009A (zh) | 1996-10-09 |
| NO961478L (no) | 1996-06-11 |
| CA2173208C (en) | 2007-01-30 |
| CN1074919C (zh) | 2001-11-21 |
| ES2105766T3 (es) | 1997-10-16 |
| GB9321061D0 (en) | 1993-12-01 |
| GR3024787T3 (en) | 1998-01-30 |
| NO961478D0 (no) | 1996-04-12 |
| EP0723444A1 (de) | 1996-07-31 |
| DK0723444T3 (da) | 1997-12-29 |
| WO1995010276A1 (en) | 1995-04-20 |
| NO309304B1 (no) | 2001-01-15 |
| DE69403969D1 (de) | 1997-07-31 |
| AU7859394A (en) | 1995-05-04 |
| AU692477B2 (en) | 1998-06-11 |
| JPH09503777A (ja) | 1997-04-15 |
| US5955479A (en) | 1999-09-21 |
| EP0723444B1 (de) | 1997-06-25 |
| KR100343314B1 (ko) | 2003-02-19 |
| HK1006421A1 (en) | 1999-02-26 |
| DE69403969T2 (de) | 1997-11-20 |
| CA2173208A1 (en) | 1995-04-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EEFA | Change of the company name | ||
| EEIH | Change in the person of patent owner |