ATE154609T1 - Nicht-lineare peptide, die hydropatisch komplementär zu bekannten aminosäuresequenzen sind, verfahren zur herstellung und verwendung davon - Google Patents
Nicht-lineare peptide, die hydropatisch komplementär zu bekannten aminosäuresequenzen sind, verfahren zur herstellung und verwendung davonInfo
- Publication number
- ATE154609T1 ATE154609T1 AT91830428T AT91830428T ATE154609T1 AT E154609 T1 ATE154609 T1 AT E154609T1 AT 91830428 T AT91830428 T AT 91830428T AT 91830428 T AT91830428 T AT 91830428T AT E154609 T1 ATE154609 T1 AT E154609T1
- Authority
- AT
- Austria
- Prior art keywords
- hydropatic
- complementary
- production
- amino acid
- acid sequences
- Prior art date
Links
- 150000001413 amino acids Chemical group 0.000 title 1
- 230000000295 complement effect Effects 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 230000002797 proteolythic effect Effects 0.000 abstract 2
- 102000002045 Endothelin Human genes 0.000 abstract 1
- 108050009340 Endothelin Proteins 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- ZUBDGKVDJUIMQQ-UBFCDGJISA-N endothelin-1 Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(O)=O)NC(=O)[C@H]1NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@@H](CC=2C=CC(O)=CC=2)NC(=O)[C@H](C(C)C)NC(=O)[C@H]2CSSC[C@@H](C(N[C@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N2)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](N)CSSC1)C1=CNC=N1 ZUBDGKVDJUIMQQ-UBFCDGJISA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57536—Endothelin, vasoactive intestinal contractor [VIC]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT48365A IT1242076B (it) | 1990-10-15 | 1990-10-15 | Peptidi idropaticamente complementari a sequenze aminoacidiche note covalentemente legati in maniera non lineare e procedimento per la loro sintesi |
| ITRM910261A IT1244512B (it) | 1991-04-15 | 1991-04-15 | Procedimento per l'identificazione di attivita' proteolitiche o di attivita' inibitrici di attivita' proteolitiche |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE154609T1 true ATE154609T1 (de) | 1997-07-15 |
Family
ID=26329306
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91830428T ATE154609T1 (de) | 1990-10-15 | 1991-10-14 | Nicht-lineare peptide, die hydropatisch komplementär zu bekannten aminosäuresequenzen sind, verfahren zur herstellung und verwendung davon |
| AT96114931T ATE200107T1 (de) | 1990-10-15 | 1991-10-14 | Verfahren zur feststellung von proteolitischen wirkungen und/oder deren inhibitoren |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96114931T ATE200107T1 (de) | 1990-10-15 | 1991-10-14 | Verfahren zur feststellung von proteolitischen wirkungen und/oder deren inhibitoren |
Country Status (3)
| Country | Link |
|---|---|
| EP (2) | EP0481930B1 (de) |
| AT (2) | ATE154609T1 (de) |
| DE (2) | DE69126592T2 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5674977A (en) * | 1993-02-05 | 1997-10-07 | The Ontario Cancer Institute | Branched synthetic peptide conjugate |
| EP0752425B1 (de) | 1995-06-21 | 1999-09-29 | TECNOGEN Società Consortile per azioni | Peptidliganden für die konstante Region von Immunoglobulinen |
| DE19653445C1 (de) * | 1996-03-26 | 1997-12-11 | Razvan T Dr Med Radulescu | Peptide mit antineoplastischen Eigenschaften |
| GB9814527D0 (en) | 1998-07-03 | 1998-09-02 | Cyclacel Ltd | Delivery system |
| EP1958961A3 (de) | 1998-11-13 | 2008-09-03 | Cyclacel Limited | Transportvektoren |
| GB9929466D0 (en) * | 1999-12-13 | 2000-02-09 | Proteom Ltd | Complementary peptide ligands generated from microbial genome sequences |
| GB9929469D0 (en) * | 1999-12-13 | 2000-02-09 | Proteom Ltd | Complementary peptide ligands generated from plant genomes |
| GB9929464D0 (en) * | 1999-12-13 | 2000-02-09 | Proteom Ltd | Complementary peptide ligande generated from the human genome |
| TWI480070B (zh) * | 2011-04-21 | 2015-04-11 | Univ Kaohsiung Medical | 具礦質親和能力之多歧狀胜肽構型 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4563305A (en) * | 1981-01-07 | 1986-01-07 | University Of Miami | Radiolabelled substrates for assaying mammalian enzymes |
| JPS58129998A (ja) * | 1981-11-02 | 1983-08-03 | ジエ−ムス・ウオルタ−・リヤン | 標識蛋白質性阻害剤を用いるプロテア−ゼの分析法 |
| CA1254119A (en) * | 1984-07-20 | 1989-05-16 | Lloyd A. Schick | Single step protease inhibitor assay |
| DE3783966T2 (de) * | 1986-07-29 | 1993-05-27 | Sunstar Inc | Reagens zur pruefung von periodentalen erkrankungen. |
| EP0318318A1 (de) * | 1987-11-27 | 1989-05-31 | Sensititre Limited | Urintestverfahren und Testsatz |
| CA1332347C (en) * | 1988-01-20 | 1994-10-11 | Toru Eguchi | Composition for testing periodontal diseases |
| JPH03500002U (de) * | 1988-06-27 | 1991-06-06 | ||
| US5081584A (en) * | 1989-03-13 | 1992-01-14 | United States Of America | Computer-assisted design of anti-peptides based on the amino acid sequence of a target peptide |
| ATE187738T1 (de) * | 1989-07-31 | 2000-01-15 | Tecnogen Scpa | Verfahren zur identifizierung und herstellung von bindungsstellen aufeinanderwirkender proteine |
| EP0428000A1 (de) * | 1989-11-03 | 1991-05-22 | Abbott Laboratories | Fluorogene Substrate zum Nachweis von proteolytischer Enzymaktivität |
-
1991
- 1991-10-14 DE DE69126592T patent/DE69126592T2/de not_active Expired - Fee Related
- 1991-10-14 AT AT91830428T patent/ATE154609T1/de not_active IP Right Cessation
- 1991-10-14 EP EP91830428A patent/EP0481930B1/de not_active Expired - Lifetime
- 1991-10-14 DE DE69132567T patent/DE69132567D1/de not_active Expired - Lifetime
- 1991-10-14 EP EP96114931A patent/EP0751225B1/de not_active Expired - Lifetime
- 1991-10-14 AT AT96114931T patent/ATE200107T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69126592T2 (de) | 1998-01-08 |
| EP0751225A1 (de) | 1997-01-02 |
| DE69132567D1 (de) | 2001-05-03 |
| EP0481930A2 (de) | 1992-04-22 |
| EP0481930A3 (en) | 1993-06-30 |
| EP0481930B1 (de) | 1997-06-18 |
| EP0751225B1 (de) | 2001-03-28 |
| ATE200107T1 (de) | 2001-04-15 |
| DE69126592D1 (de) | 1997-07-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |