ATE149284T1 - Neue zusammensetzungen lyophilisierter und wiederhergestellter zellen - Google Patents

Neue zusammensetzungen lyophilisierter und wiederhergestellter zellen

Info

Publication number
ATE149284T1
ATE149284T1 AT91909847T AT91909847T ATE149284T1 AT E149284 T1 ATE149284 T1 AT E149284T1 AT 91909847 T AT91909847 T AT 91909847T AT 91909847 T AT91909847 T AT 91909847T AT E149284 T1 ATE149284 T1 AT E149284T1
Authority
AT
Austria
Prior art keywords
lyophilized
new compositions
cells
restored cells
matter
Prior art date
Application number
AT91909847T
Other languages
English (en)
Inventor
Raymond P Goodrich Jr
Victoria A Wong
Original Assignee
Cobe Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cobe Lab filed Critical Cobe Lab
Application granted granted Critical
Publication of ATE149284T1 publication Critical patent/ATE149284T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0205Chemical aspects
    • A01N1/021Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0215Disinfecting agents, e.g. antimicrobials for preserving living parts
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0205Chemical aspects
    • A01N1/021Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0221Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/19Platelets; Megacaryocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Hematology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AT91909847T 1990-05-17 1991-05-17 Neue zusammensetzungen lyophilisierter und wiederhergestellter zellen ATE149284T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/525,392 US5213814A (en) 1989-04-10 1990-05-17 Lyophilized and reconstituted blood platelet compositions

Publications (1)

Publication Number Publication Date
ATE149284T1 true ATE149284T1 (de) 1997-03-15

Family

ID=24093064

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91909847T ATE149284T1 (de) 1990-05-17 1991-05-17 Neue zusammensetzungen lyophilisierter und wiederhergestellter zellen

Country Status (10)

Country Link
US (1) US5213814A (de)
EP (1) EP0483329B1 (de)
JP (1) JPH05500231A (de)
AT (1) ATE149284T1 (de)
AU (1) AU7888391A (de)
CA (1) CA2064228C (de)
DE (1) DE69124915D1 (de)
IL (1) IL98182A0 (de)
WO (1) WO1991017655A1 (de)
ZA (1) ZA913774B (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL90188A0 (en) * 1988-05-18 1989-12-15 Cryopharm Corp Process and medium for the lyophilization of erythrocytes
US5045446A (en) * 1988-08-26 1991-09-03 Cryopharm Corporation Lyophilization of cells
US5428008A (en) * 1989-04-14 1995-06-27 Prp, Inc. Therapeutic composition of micellar structures capable of promoting hemotasis
US6251644B1 (en) 1990-04-16 2001-06-26 Baxter International, Inc. Method for inactivating non-enveloped viral contaminants with a photosensitizer by increasing viral permeability to the photosensitizer
US6187572B1 (en) * 1990-04-16 2001-02-13 Baxter International Inc. Method of inactivation of viral and bacterial blood contaminants
EP0484519A4 (en) * 1990-05-25 1993-12-29 Cryopharm Corporation Process for lyophilizing cells, cell-like materials and platelets in a mixture of biocompatible amphipathic polymers
US5376524A (en) * 1991-04-01 1994-12-27 Thomas Jefferson University Platelet storage medium containing acetate and phosphate
US5569579A (en) * 1991-04-01 1996-10-29 Thomas Jefferson University Synthetic-based platelet storage media
ES2194013T3 (es) * 1992-05-29 2003-11-16 Univ North Carolina Plaquetas de sangre humana de secado fijo farmaceuticamente aceptables.
US5690963A (en) * 1995-06-30 1997-11-25 The United States Of America As Represented By The Secretary Of The Navy Freeze dried red blood cells
US5736313A (en) * 1995-10-20 1998-04-07 The United States Of America As Represented By The Secretary Of The Navy Method of lyophilizing platelets by incubation with high carbohydrate concentrations and supercooling prior to freezing
EP0921814A4 (de) 1996-03-29 2001-10-04 Life Technologies Inc Verfahren zur Erhöhung der Lebensfähigkeit und der Transformationseffizienz von Bakterien während der Lagerung bei tiefen Temperaturen
DE19634313A1 (de) * 1996-08-24 1998-02-26 Behringwerke Ag Methode zur Stabilisierung von Plättchen
JP2001512310A (ja) 1997-02-12 2001-08-21 ライフ テクノロジーズ,インコーポレイテッド コンピテント細胞を凍結乾燥するための方法
AT407484B (de) * 1997-11-12 2001-03-26 Bio Prod & Bio Eng Ag Arzneimittel zur förderung der wundheilung
US6139878A (en) * 1998-04-27 2000-10-31 Aventis Behring, Llc Method for preparing a diafiltered stabilized blood product
US6413713B1 (en) 1998-10-30 2002-07-02 Hyperbaric Systems Method for preserving blood platelets
ATE389414T1 (de) * 1999-09-08 2008-04-15 Chugai Pharmaceutical Co Ltd Stabile proteinlösung abgefüllt in einem behältnis aus hydrophobem harz und eine methode zur stabilisierung derselben
AU2594001A (en) 1999-12-21 2001-07-03 Bioenergy Inc. Compositions for the storage of platelets
AU2001234978A1 (en) 2000-02-10 2001-08-20 The Regents Of The University Of California Therapeutic platelets and methods
US6770478B2 (en) 2000-02-10 2004-08-03 The Regents Of The University Of California Erythrocytic cells and method for preserving cells
WO2003000052A1 (en) * 2001-06-26 2003-01-03 Human Biosystems Preservation of blood platelets at cold temperatures
GB0230152D0 (en) * 2002-12-24 2003-02-05 Sinvent As Product
US7029839B2 (en) 2003-04-23 2006-04-18 Human Biosystems Methods and solutions for storing donor organs
US20040229205A1 (en) * 2003-05-16 2004-11-18 Ericson Daniel G. Compositions for the storage of platelets
EP1659862A2 (de) 2003-08-04 2006-05-31 Human Biosystems Konservierung von blutzellen
EP1784639B1 (de) 2004-08-12 2010-01-20 CELLPHIRE, Inc. Verfahren zur herstellung gefriergetrockneter blutplättchen, gefriergetrocknete blutplättchen enthaltende zusammensetzungen und verwendungsverfahren
KR101368924B1 (ko) 2005-11-17 2014-03-04 니뽄젠야쿠코교 가부시키가이샤 세포 보존용 수용액
US20090117057A1 (en) * 2007-11-06 2009-05-07 Shanbrom Technologies, Llc Grape Polyphenolics for Platelet and Bacterial Control
AU2013365623B2 (en) * 2012-12-20 2017-08-24 Omrix Biopharmaceuticals Ltd. Viral inactivated biological mixture
EP3151662B1 (de) 2014-06-09 2020-10-21 Terumo BCT, Inc. Lyophilisierung
JP7110360B2 (ja) 2017-10-09 2022-08-01 テルモ ビーシーティー バイオテクノロジーズ,エルエルシー 凍結乾燥方法
EP3886879A4 (de) 2018-11-30 2022-12-07 Cellphire Inc. Thrombozyten als freisetzungsmittel
US20200208110A1 (en) 2018-11-30 2020-07-02 Cellphire, Inc. PLATELETS LOADED WITH mRNA
US11604026B2 (en) 2019-03-14 2023-03-14 Terumo Bct Biotechnologies, Llc Lyophilization loading tray assembly and system
AU2020267368B2 (en) 2019-05-03 2023-05-04 Cellphire, Inc. Materials and methods for producing blood products
US11701388B2 (en) 2019-08-16 2023-07-18 Cellphire, Inc. Thrombosomes as an antiplatelet agent reversal agent
WO2021158645A1 (en) 2020-02-04 2021-08-12 Cellphire, Inc. Methods of treating congenital hemophilia with anti-fibrinolytic loaded platelets
CN114617903B (zh) * 2022-03-15 2024-05-24 中国人民解放军总医院第一医学中心 一种用于血浆冻干的组合物及其应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2786014A (en) * 1952-09-10 1957-03-19 James L Tullis Platelet preservation
US3303662A (en) * 1963-03-01 1967-02-14 Union Carbide Corp Process for cell preservation
BE643051A (de) * 1963-05-31 1964-05-15
DE2546166A1 (de) * 1975-10-15 1977-04-28 Behringwerke Ag Gegerbte thrombozyten
US4059967A (en) * 1976-02-19 1977-11-29 The Community Blood Council Of Greater New York, Inc. Process for freezing blood platelets
US4961928A (en) * 1986-03-19 1990-10-09 American Red Cross Synthetic, plasma-free, transfusible storage medium for red blood cells and platelets
US4764463A (en) * 1986-10-30 1988-08-16 The University Of Tennessee Research Corporation Platelet cyropreservation
US5153004A (en) * 1989-06-02 1992-10-06 Cryopharm Corporation Freezing and thawing of erythrocytes
US5178884A (en) * 1988-05-18 1993-01-12 Cryopharm Corporation Lyophilized and reconstituted red blood cell compositions
US4874690A (en) * 1988-08-26 1989-10-17 Cryopharm Corporation Lyophilization of red blood cells
EP0356258A3 (de) * 1988-08-26 1990-06-06 Cryopharm Corporation Gefriertrocknungsmethode für rote Blutkörperchen und Mittel dafür
US4973327A (en) * 1989-11-01 1990-11-27 Cryopharm Blood bag for lyophilization
IL97856A0 (en) * 1990-04-16 1992-06-21 Cryopharm Corp Compositions containing cellular blood matter and method and processes for the inactivation of viral and bacterial blood components
EP0484519A4 (en) * 1990-05-25 1993-12-29 Cryopharm Corporation Process for lyophilizing cells, cell-like materials and platelets in a mixture of biocompatible amphipathic polymers
WO1992014360A1 (en) * 1991-02-15 1992-09-03 Cryopharm Corporation Method of lyophilization and reconstitution of mixtures of nucleated non-mammalian cells and blood matter

Also Published As

Publication number Publication date
CA2064228A1 (en) 1991-11-18
WO1991017655A1 (en) 1991-11-28
US5213814A (en) 1993-05-25
IL98182A0 (en) 1992-06-21
AU7888391A (en) 1991-12-10
EP0483329A4 (en) 1993-08-11
EP0483329B1 (de) 1997-03-05
EP0483329A1 (de) 1992-05-06
JPH05500231A (ja) 1993-01-21
ZA913774B (en) 1992-02-26
CA2064228C (en) 1999-04-06
DE69124915D1 (de) 1997-04-10

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