ATE147754T1 - Reinigung und verwendung von pertactin, eines bordetella pertussis aussenmembranproteins - Google Patents

Reinigung und verwendung von pertactin, eines bordetella pertussis aussenmembranproteins

Info

Publication number
ATE147754T1
ATE147754T1 AT91906730T AT91906730T ATE147754T1 AT E147754 T1 ATE147754 T1 AT E147754T1 AT 91906730 T AT91906730 T AT 91906730T AT 91906730 T AT91906730 T AT 91906730T AT E147754 T1 ATE147754 T1 AT E147754T1
Authority
AT
Austria
Prior art keywords
pertactin
purification
purified
bordetella pertussis
membrane protein
Prior art date
Application number
AT91906730T
Other languages
English (en)
Inventor
Gail Jackson
Raafat Fahim
Larry Tan
Pele Chong
John Vose
Michel Klein
Original Assignee
Connaught Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10673904&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE147754(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Connaught Lab filed Critical Connaught Lab
Application granted granted Critical
Publication of ATE147754T1 publication Critical patent/ATE147754T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • Y10S530/825Bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT91906730T 1990-04-04 1991-04-03 Reinigung und verwendung von pertactin, eines bordetella pertussis aussenmembranproteins ATE147754T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909007657A GB9007657D0 (en) 1990-04-04 1990-04-04 Purification of a pertussis outer membrane protein(omp69)

Publications (1)

Publication Number Publication Date
ATE147754T1 true ATE147754T1 (de) 1997-02-15

Family

ID=10673904

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91906730T ATE147754T1 (de) 1990-04-04 1991-04-03 Reinigung und verwendung von pertactin, eines bordetella pertussis aussenmembranproteins

Country Status (11)

Country Link
US (2) US5444159A (de)
EP (2) EP0527753B2 (de)
JP (1) JP2549225B2 (de)
AT (1) ATE147754T1 (de)
CA (1) CA2079887C (de)
DE (3) DE527753T1 (de)
DK (1) DK0527753T4 (de)
ES (2) ES2088374T5 (de)
GB (1) GB9007657D0 (de)
GR (2) GR3022769T3 (de)
WO (1) WO1991015505A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8412207D0 (en) * 1984-05-12 1984-06-20 Wellcome Found Antigenic preparations
GB8910570D0 (en) 1989-05-08 1989-06-21 Wellcome Found Acellular vaccine
US6197548B1 (en) 1990-04-02 2001-03-06 Medeva Pharma Limited Transformed Pichia expressing the pertactin antigen
NL9002092A (nl) * 1990-09-25 1992-04-16 Nederlanden Staat Vaccin, geschikt voor de bestrijding van bordetella pertussis.
US6444211B2 (en) * 1991-04-03 2002-09-03 Connaught Laboratories, Inc. Purification of a pertussis outer membrane protein
GB9304399D0 (en) * 1993-03-04 1993-04-21 Smithkline Beecham Biolog Novel process
ATE183194T1 (de) * 1994-04-28 1999-08-15 Takeda Chemical Industries Ltd Verfahren zur trennung von protektiven verbindungen aus bordetella pertussis
EP1234579A1 (de) * 1995-05-04 2002-08-28 Aventis Pasteur Limited Azelluläre Pertussis-Impfstoffe und Verfahren zu deren Herstellung
US5877298A (en) * 1995-05-04 1999-03-02 Connaught Lab Acellular pertussis vaccines and methods of preparing thereof
JP3745805B2 (ja) * 1995-10-24 2006-02-15 日本ケミカルリサーチ株式会社 トロンボモジュリンの精製方法
US5739313A (en) 1995-11-13 1998-04-14 Regents Of The University Of Minnesota Radionuclide labeling of vitamin B12 and coenzymes thereof
AU724743B2 (en) * 1996-05-31 2000-09-28 Genetics Institute, Llc IL-12 as an adjuvant for Bordetella Pertussis vaccines
TR199802783T2 (xx) 1996-07-02 1999-03-22 Connaught Laboratories Limited �ok de�erli DTP polyo a��lar.
WO2003059935A2 (en) * 2001-12-21 2003-07-24 Immunex Corporation Methods for purifying protein
WO2009016651A1 (en) * 2007-07-31 2009-02-05 Panacea Biotec Limited Simplified means for obtaining prn from bordetella pertussis
EP2430040A1 (de) 2009-05-11 2012-03-21 Novartis AG Antigenaufreinigungs­verfahren für pertactinantigen
CN102584958A (zh) * 2012-02-08 2012-07-18 北京天坛生物制品股份有限公司 百日咳杆菌69kd外膜蛋白的纯化方法
US8916173B2 (en) 2013-03-08 2014-12-23 Crucell Holland B.V. Acellular pertussis vaccine
KR102426041B1 (ko) * 2017-08-01 2022-07-29 주식회사 녹십자 냉동 및 해동 과정을 포함하는 백일해균 유래 단백질 수득 방법
CN113151081A (zh) * 2021-04-21 2021-07-23 深圳市儿童医院 一种百日咳鲍特菌培养基及其制备方法
WO2024056508A1 (en) 2022-09-15 2024-03-21 Cube Biotech Gmbh In vitro diagnostic method for detecting the presence of a target by using stabilized membrane proteins

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5237052A (en) * 1984-05-12 1993-08-17 Burroughs Wellcome Company Antigenic preparations and isolation of such preparations
GB8412207D0 (en) * 1984-05-12 1984-06-20 Wellcome Found Antigenic preparations
GB8807860D0 (en) * 1988-04-05 1988-05-05 Connaught Lab Pertussis vaccine
US5101014A (en) * 1989-02-10 1992-03-31 United States Of America Process for the purification of a 69,000 da outer membrane protein of Bordetella pertussis
US5276142A (en) * 1989-12-11 1994-01-04 American Cyanamid Company Process for purification of a 69000 dalton antigenic protein from Bordetella pertussis
GB9007416D0 (en) 1990-04-02 1990-05-30 Wellcome Found Expression of heterologous protein in yeast

Also Published As

Publication number Publication date
CA2079887A1 (en) 1991-10-05
GR970300034T1 (en) 1997-10-31
EP0527753A1 (de) 1993-02-24
DE761230T1 (de) 1997-09-25
ES2088374T3 (es) 1997-05-16
JPH05506649A (ja) 1993-09-30
GB9007657D0 (en) 1990-05-30
WO1991015505A1 (en) 1991-10-17
GR3022769T3 (en) 1997-06-30
US5444159A (en) 1995-08-22
DE527753T1 (de) 1996-11-28
JP2549225B2 (ja) 1996-10-30
DE69124235D1 (de) 1997-02-27
US5667787A (en) 1997-09-16
ES2104535T1 (es) 1997-10-16
ES2088374T5 (es) 2004-08-16
DE69124235T2 (de) 1997-05-28
DE69124235T3 (de) 2004-06-03
EP0761230A2 (de) 1997-03-12
EP0761230A3 (de) 1999-01-20
DK0527753T3 (da) 1997-04-07
DK0527753T4 (da) 2004-03-22
EP0527753B1 (de) 1997-01-15
ES2088374T1 (es) 1996-08-16
EP0527753B2 (de) 2003-12-17
CA2079887C (en) 1998-06-23

Similar Documents

Publication Publication Date Title
ATE147754T1 (de) Reinigung und verwendung von pertactin, eines bordetella pertussis aussenmembranproteins
LU91591I2 (fr) Combinaison d'antoxine diphtérique, d'anatoxine tétanique,d'anatoxine coquelucheuse, d'hémagglutinine filamenteuse, de pertactine, d'agglutinogènes fimbriaux coquelucheux 2 et 3 et de virus poliomyélitique inactivé type1, type 2 et type 3 (Triaxis Polio)
LU93036I2 (fr) Vaccin diphtérirque, tétanique, coquelucheux (composant acelluaire, et incluant fimbriae des types 2 et 3), de l'hépatite b (adnr), poliomyélitique (inactivé), et conjugué de l'haemophilus de type b (adsrobé)
ATE128628T1 (de) Faser-hemagglutinin von bordetella pertussis als träger für konjugierten impfstoff.
LU90203I2 (fr) Anatoxine diphtérique anatoxine tétanique trois antigènes coquelucheux purifiés (toxine pertussique tp hémagglutinine filamenteuse (haf) et pertactine (protéine de membrane externe 69 kd) et le principal antigène de surface du virus de l'hépatite b (vhb) purfié (infanrix hepb) et ses dérivés pharmaceutiquement acceptables
ES2359806T3 (es) Vacunas contra la tos ferina acelulares y procedimientos de preparación de las mismas.
BR9712917A (pt) Vacina pertussis acelular com toxóides diftérico e tetânico
DE3855442D1 (de) Verfahren zur Gewinnung von Schutzantigenen gegen Bordetella-Infektionen und toxische Prozesse
CA2075711C (en) Vaccine and method therefor
ATE96036T1 (de) Verfahren zum zuechten von bordetella-pertussis, ein pertussis-toxoid und ein pertussis-impfstoff.
AU635083B2 (en) Purification of b.pertussis toxin and filamentous hemagglutinin antigen
LU90378I2 (fr) Tetravac
ATE420951T1 (de) Schützende epitope von adenylate-zyklase- hämolysin(ac-hly) und ihre verwendung zur behandlung oder verhütung von bordetella- infektionen
CA2224052C (en) Pertussis outer membrane protein
GB9611501D0 (en) Vaccine compositions
Bhandari et al. Testing of adsorbed diphtheria-pertussis-tetanus (DPT) vaccine for freedom from abnormal toxicity

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
UEP Publication of translation of european patent specification

Ref document number: 0527753

Country of ref document: EP

EELA Cancelled due to lapse of time