ATE142203T1 - N-iodopropargyl-hydantoin-verbindungen, zusammensetzungen, herstellung und verwendung als mikrobizide - Google Patents

N-iodopropargyl-hydantoin-verbindungen, zusammensetzungen, herstellung und verwendung als mikrobizide

Info

Publication number
ATE142203T1
ATE142203T1 AT93303988T AT93303988T ATE142203T1 AT E142203 T1 ATE142203 T1 AT E142203T1 AT 93303988 T AT93303988 T AT 93303988T AT 93303988 T AT93303988 T AT 93303988T AT E142203 T1 ATE142203 T1 AT E142203T1
Authority
AT
Austria
Prior art keywords
alkyl
iodopropargyl
halogen
optionally substituted
microbicides
Prior art date
Application number
AT93303988T
Other languages
English (en)
Inventor
Adam Chi-Tung Hsu
Steven Howard Shaber
Enrique Luis Michelotti
Original Assignee
Rohm & Haas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rohm & Haas filed Critical Rohm & Haas
Application granted granted Critical
Publication of ATE142203T1 publication Critical patent/ATE142203T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Environmental Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Cosmetics (AREA)
  • Fodder In General (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
AT93303988T 1992-05-26 1993-05-21 N-iodopropargyl-hydantoin-verbindungen, zusammensetzungen, herstellung und verwendung als mikrobizide ATE142203T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/888,572 US5346913A (en) 1992-05-26 1992-05-26 N-iodopropargyl hydantoin compounds, compositions, preparation, and use as antimicrobial agents

Publications (1)

Publication Number Publication Date
ATE142203T1 true ATE142203T1 (de) 1996-09-15

Family

ID=25393441

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93303988T ATE142203T1 (de) 1992-05-26 1993-05-21 N-iodopropargyl-hydantoin-verbindungen, zusammensetzungen, herstellung und verwendung als mikrobizide

Country Status (8)

Country Link
US (1) US5346913A (de)
EP (1) EP0572191B1 (de)
JP (1) JPH0656796A (de)
AT (1) ATE142203T1 (de)
BR (1) BR9302068A (de)
CA (1) CA2096395A1 (de)
DE (1) DE69304420T2 (de)
MX (1) MX9302944A (de)

Families Citing this family (32)

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CA2216765A1 (en) * 1996-10-11 1998-04-11 Rohm And Haas Company Halopropargyl compounds as marine antifouling agents
US6143204A (en) * 1998-06-19 2000-11-07 Lonza Inc. Stabilization of iodopropynl compounds
WO2002067685A1 (en) * 2001-02-26 2002-09-06 Lonza Inc. Stable preservative formulations comprising halopropynyl compounds and butoxydiglycol solvent
EP1554572B1 (de) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
PL369337A1 (en) * 2001-10-01 2005-04-18 Bristol-Myers Squibb Company Spiro-hydantoin compounds useful as anti-inflammatory agents
JP2005104835A (ja) * 2001-10-10 2005-04-21 Kaneka Corp 新規５−置換ヒダントイン誘導体及びその製造方法
AU2005232526B2 (en) 2004-02-24 2011-06-23 The Regents Of The University Of California Methods and materials for assessing prostate cancer therapies and compounds
WO2005090316A1 (en) * 2004-03-12 2005-09-29 Wyeth HYDANTOINS HAVING RNase MODULATORY ACTIVITY
TW200616634A (en) * 2004-10-01 2006-06-01 Bristol Myers Squibb Co Crystalline forms and process for preparing spiro-hydantoin compounds
US7186727B2 (en) * 2004-12-14 2007-03-06 Bristol-Myers Squibb Company Pyridyl-substituted spiro-hydantoin compounds and use thereof
US20060142319A1 (en) * 2004-12-14 2006-06-29 Bang-Chi Chen Pyridyl-substituted spiro-hydantoin crystalline forms and process
EP3827747A1 (de) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharmainformatiksystem
US7709517B2 (en) 2005-05-13 2010-05-04 The Regents Of The University Of California Diarylhydantoin compounds
CN100397998C (zh) * 2006-03-16 2008-07-02 上海交通大学 复合型霉菌毒素吸附剂
EP2656842B1 (de) 2006-03-27 2016-08-10 The Regents of The University of California Androgenrezeptor-modulator zur behandlung von prostatakrebs und androgenrezeptor-assoziierte erkrankungen
EP3020706A1 (de) 2006-03-29 2016-05-18 The Regents Of The University Of California Diarylthiohydantoinverbindungen zur behandlung hyperproliferativer erkrankungen
US8168667B2 (en) 2006-05-31 2012-05-01 Galapagos Nv Imidazolidine derivatives, uses therefor, preparation thereof and compositions comprising such
CA2661605A1 (en) * 2006-08-31 2008-03-06 Schering Corporation Hydantoin derivatives useful as antibacterial agents
EP2063905B1 (de) 2006-09-18 2014-07-30 Raptor Pharmaceutical Inc Behandlungen von lebererkrankungen durch verabreichung von konjugaten aus rezeptor-assoziierten proteinen
CA2966280A1 (en) 2007-10-26 2009-04-30 The Regents Of The University Of California Diarylhydantoin compounds
GB2463514C (en) 2008-09-11 2018-09-26 Galapagos Nv Imidazolidine compounds and uses therefor
NZ616673A (en) 2009-02-20 2014-08-29 To Bbb Holding B V Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
PT3124481T (pt) 2010-02-16 2018-06-18 Aragon Pharmaceuticals Inc Moduladores do receptor de androgénios e suas utilizações
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
EA030128B1 (ru) 2012-09-26 2018-06-29 Арагон Фармасьютикалз, Инк. Способ лечения неметастатического кастрационно-резистентного рака простаты
JOP20200097A1 (ar) 2013-01-15 2017-06-16 Aragon Pharmaceuticals Inc معدل مستقبل أندروجين واستخداماته
CN105399681A (zh) * 2014-08-22 2016-03-16 中国航天科工集团第六研究院四十六所 1,3-双(丙炔基)-5,5-二甲基海因及其合成方法和应用
TWI726969B (zh) 2016-01-11 2021-05-11 比利時商健生藥品公司 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
US10702508B2 (en) 2017-10-16 2020-07-07 Aragon Pharmaceuticals, Inc. Anti-androgens for the treatment of non-metastatic castration-resistant prostate cancer
CN111533694B (zh) * 2020-06-05 2023-03-14 河南牧业经济学院 一种2-亚胺基乙内酰脲化合物的合成方法
RU2763731C1 (ru) * 2021-06-17 2021-12-30 Федеральное государственное автономное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет" (ПГНИУ) Применение 9-ароил-8-гидрокси-6-(2-гидроксиалкил)-1,3-диалкил-2-тиоксо-1,3,6-триазаспиро[4.4]нон-8-ен-4,7-дионов в качестве средств, обладающих противомикробной активностью

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57197268A (en) * 1981-05-29 1982-12-03 Sumitomo Chem Co Ltd Substituted phenylhydantoin derivative, its preparation, and herbicide containing the same as active ingredient
US4753957A (en) * 1981-09-28 1988-06-28 Rohm And Haas Company Substituted 2,4-imidazolidinediones and fungicidal compositions
DE3241265A1 (de) * 1982-11-09 1984-05-10 Bayer Ag, 5090 Leverkusen 3-(3-jodpropargyl)-benzo-1,2,3-triazin-4-one, verfahren zu ihrer herstellung und ihre verwendung in mikrobiziden mitteln
US4616004A (en) * 1984-09-27 1986-10-07 Chevron Research Company 1-iodopropargyl-3,4-disubstituted-Δ2 -1,2,4-triazolidin-5-one fungicides
US4639460A (en) * 1985-08-05 1987-01-27 Chevron Research Company Fungicidal substituted N-(1-iodopropargyl)thiazolidinones
US4827020A (en) * 1987-03-24 1989-05-02 Sumitomo Chemical Company, Limited Propargyl amide precursor to 1-propargyl-2,4-dioxoimidazolidine
CA2019162A1 (en) * 1989-06-22 1990-12-22 Adam Chi-Tung Hsu Halopropargyl compounds, compositions, uses and processes of preparation
IT1268325B1 (it) * 1994-08-05 1997-02-27 Sasib Spa Macchina impacchettatrice per oggetti astiformi delicati, in particolare per sigarette, o simili.

Also Published As

Publication number Publication date
JPH0656796A (ja) 1994-03-01
CA2096395A1 (en) 1993-11-27
DE69304420T2 (de) 1997-03-13
US5346913A (en) 1994-09-13
EP0572191A1 (de) 1993-12-01
MX9302944A (es) 1994-05-31
EP0572191B1 (de) 1996-09-04
BR9302068A (pt) 1993-11-30
DE69304420D1 (de) 1996-10-10

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Legal Events

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