DE69304420T2 - N-Iodopropargyl-Hydantoin-Verbindungen, Zusammensetzungen, Herstellung und Verwendung als Mikrobizide - Google Patents
N-Iodopropargyl-Hydantoin-Verbindungen, Zusammensetzungen, Herstellung und Verwendung als MikrobizideInfo
- Publication number
- DE69304420T2 DE69304420T2 DE69304420T DE69304420T DE69304420T2 DE 69304420 T2 DE69304420 T2 DE 69304420T2 DE 69304420 T DE69304420 T DE 69304420T DE 69304420 T DE69304420 T DE 69304420T DE 69304420 T2 DE69304420 T2 DE 69304420T2
- Authority
- DE
- Germany
- Prior art keywords
- iodopropargyl
- alkyl
- halogen
- optionally substituted
- microbicides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Zoology (AREA)
- Pest Control & Pesticides (AREA)
- Environmental Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Fodder In General (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/888,572 US5346913A (en) | 1992-05-26 | 1992-05-26 | N-iodopropargyl hydantoin compounds, compositions, preparation, and use as antimicrobial agents |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69304420D1 DE69304420D1 (de) | 1996-10-10 |
DE69304420T2 true DE69304420T2 (de) | 1997-03-13 |
Family
ID=25393441
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69304420T Expired - Fee Related DE69304420T2 (de) | 1992-05-26 | 1993-05-21 | N-Iodopropargyl-Hydantoin-Verbindungen, Zusammensetzungen, Herstellung und Verwendung als Mikrobizide |
Country Status (8)
Country | Link |
---|---|
US (1) | US5346913A (de) |
EP (1) | EP0572191B1 (de) |
JP (1) | JPH0656796A (de) |
AT (1) | ATE142203T1 (de) |
BR (1) | BR9302068A (de) |
CA (1) | CA2096395A1 (de) |
DE (1) | DE69304420T2 (de) |
MX (1) | MX9302944A (de) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2216765A1 (en) * | 1996-10-11 | 1998-04-11 | Rohm And Haas Company | Halopropargyl compounds as marine antifouling agents |
US6143204A (en) * | 1998-06-19 | 2000-11-07 | Lonza Inc. | Stabilization of iodopropynl compounds |
US20030039580A1 (en) * | 2001-02-26 | 2003-02-27 | Lonza Inc. | Stable preservative formulations comprising halopropynyl compounds and butoxydiglycol solvent |
AU2002322720B2 (en) | 2001-07-25 | 2008-11-13 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
CA2462112A1 (en) | 2001-10-01 | 2003-04-10 | Bristol-Myers Squibb Company | Spiro-hydantoin compounds useful as anti-inflammatory agents |
JP2005104835A (ja) * | 2001-10-10 | 2005-04-21 | Kaneka Corp | 新規5−置換ヒダントイン誘導体及びその製造方法 |
US7718684B2 (en) | 2004-02-24 | 2010-05-18 | The Regents Of The University Of California | Methods and materials for assessing prostate cancer therapies and compounds |
US20050203156A1 (en) * | 2004-03-12 | 2005-09-15 | Wyeth | Hydantoins having RNase modulatory activity |
TW200616634A (en) * | 2004-10-01 | 2006-06-01 | Bristol Myers Squibb Co | Crystalline forms and process for preparing spiro-hydantoin compounds |
US20060142319A1 (en) * | 2004-12-14 | 2006-06-29 | Bang-Chi Chen | Pyridyl-substituted spiro-hydantoin crystalline forms and process |
US7186727B2 (en) * | 2004-12-14 | 2007-03-06 | Bristol-Myers Squibb Company | Pyridyl-substituted spiro-hydantoin compounds and use thereof |
JP2008539047A (ja) | 2005-04-28 | 2008-11-13 | プロテウス バイオメディカル インコーポレイテッド | ファーマインフォーマティックスシステム |
US7709517B2 (en) | 2005-05-13 | 2010-05-04 | The Regents Of The University Of California | Diarylhydantoin compounds |
CN100397998C (zh) * | 2006-03-16 | 2008-07-02 | 上海交通大学 | 复合型霉菌毒素吸附剂 |
PL2368550T3 (pl) | 2006-03-27 | 2014-01-31 | Univ California | Modulator receptorów androgenowych do leczenia raka gruczołu krokowego i chorób związanych z receptorami androgenów |
EP2439196A1 (de) | 2006-03-29 | 2012-04-11 | The Regents of The University of California | Diarylthiohydantoin-Verbindungen zur Anwendung in einem Verfahren zur Behandlung einer hyperproliferativen Erkrankung |
US8168667B2 (en) | 2006-05-31 | 2012-05-01 | Galapagos Nv | Imidazolidine derivatives, uses therefor, preparation thereof and compositions comprising such |
WO2008027466A1 (en) * | 2006-08-31 | 2008-03-06 | Schering Corporation | Hydantoin derivatives useful as antibacterial agents |
JP2010503710A (ja) | 2006-09-18 | 2010-02-04 | ラプトール ファーマシューティカル インコーポレイテッド | 受容体関連タンパク質(rap)結合体の投与による肝障害の処置 |
CA2966280A1 (en) | 2007-10-26 | 2009-04-30 | The Regents Of The University Of California | Diarylhydantoin compounds |
GB2463514C (en) | 2008-09-11 | 2018-09-26 | Galapagos Nv | Imidazolidine compounds and uses therefor |
ES2919563T3 (es) | 2009-02-20 | 2022-07-27 | Enhanx Biopharm Inc | Sistema de administración de medicamentos a base de glutatión |
ES2942923T3 (es) | 2009-05-06 | 2023-06-07 | Laboratory Skin Care Inc | Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas |
EP3124481B1 (de) | 2010-02-16 | 2018-03-28 | Aragon Pharmaceuticals, Inc. | Androgenrezeptormodulatoren und verwendungen davon |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
CA2885415C (en) | 2012-09-26 | 2021-06-29 | Aragon Pharmaceuticals, Inc. | Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer |
JOP20200097A1 (ar) | 2013-01-15 | 2017-06-16 | Aragon Pharmaceuticals Inc | معدل مستقبل أندروجين واستخداماته |
CN105399681A (zh) * | 2014-08-22 | 2016-03-16 | 中国航天科工集团第六研究院四十六所 | 1,3-双(丙炔基)-5,5-二甲基海因及其合成方法和应用 |
TWI726969B (zh) | 2016-01-11 | 2021-05-11 | 比利時商健生藥品公司 | 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物 |
EP3697398A1 (de) | 2017-10-16 | 2020-08-26 | Aragon Pharmaceuticals, Inc. | Antiandrogene zur behandlung von nichtmetastatischem kastrationsresistentem prostatakrebs |
CN111533694B (zh) * | 2020-06-05 | 2023-03-14 | 河南牧业经济学院 | 一种2-亚胺基乙内酰脲化合物的合成方法 |
RU2763731C1 (ru) * | 2021-06-17 | 2021-12-30 | Федеральное государственное автономное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет" (ПГНИУ) | Применение 9-ароил-8-гидрокси-6-(2-гидроксиалкил)-1,3-диалкил-2-тиоксо-1,3,6-триазаспиро[4.4]нон-8-ен-4,7-дионов в качестве средств, обладающих противомикробной активностью |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57197268A (en) * | 1981-05-29 | 1982-12-03 | Sumitomo Chem Co Ltd | Substituted phenylhydantoin derivative, its preparation, and herbicide containing the same as active ingredient |
US4753957A (en) * | 1981-09-28 | 1988-06-28 | Rohm And Haas Company | Substituted 2,4-imidazolidinediones and fungicidal compositions |
DE3241265A1 (de) * | 1982-11-09 | 1984-05-10 | Bayer Ag, 5090 Leverkusen | 3-(3-jodpropargyl)-benzo-1,2,3-triazin-4-one, verfahren zu ihrer herstellung und ihre verwendung in mikrobiziden mitteln |
US4616004A (en) * | 1984-09-27 | 1986-10-07 | Chevron Research Company | 1-iodopropargyl-3,4-disubstituted-Δ2 -1,2,4-triazolidin-5-one fungicides |
US4639460A (en) * | 1985-08-05 | 1987-01-27 | Chevron Research Company | Fungicidal substituted N-(1-iodopropargyl)thiazolidinones |
US4827020A (en) * | 1987-03-24 | 1989-05-02 | Sumitomo Chemical Company, Limited | Propargyl amide precursor to 1-propargyl-2,4-dioxoimidazolidine |
CA2019162A1 (en) * | 1989-06-22 | 1990-12-22 | Adam Chi-Tung Hsu | Halopropargyl compounds, compositions, uses and processes of preparation |
IT1268325B1 (it) * | 1994-08-05 | 1997-02-27 | Sasib Spa | Macchina impacchettatrice per oggetti astiformi delicati, in particolare per sigarette, o simili. |
-
1992
- 1992-05-26 US US07/888,572 patent/US5346913A/en not_active Expired - Fee Related
-
1993
- 1993-05-17 CA CA002096395A patent/CA2096395A1/en not_active Abandoned
- 1993-05-20 MX MX9302944A patent/MX9302944A/es not_active Application Discontinuation
- 1993-05-21 EP EP93303988A patent/EP0572191B1/de not_active Expired - Lifetime
- 1993-05-21 DE DE69304420T patent/DE69304420T2/de not_active Expired - Fee Related
- 1993-05-21 AT AT93303988T patent/ATE142203T1/de not_active IP Right Cessation
- 1993-05-26 BR BR9302068A patent/BR9302068A/pt not_active Application Discontinuation
- 1993-05-26 JP JP5146979A patent/JPH0656796A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
BR9302068A (pt) | 1993-11-30 |
CA2096395A1 (en) | 1993-11-27 |
US5346913A (en) | 1994-09-13 |
EP0572191B1 (de) | 1996-09-04 |
MX9302944A (es) | 1994-05-31 |
EP0572191A1 (de) | 1993-12-01 |
ATE142203T1 (de) | 1996-09-15 |
DE69304420D1 (de) | 1996-10-10 |
JPH0656796A (ja) | 1994-03-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |