ATE14218T1 - Trijodbenzoylderivate welche sich fuer nichtionische kontrastmittelloesungen eigenen sowie amino-dioxepan-zwischenprodukte fuer die synthese dieser verbindungen. - Google Patents
Trijodbenzoylderivate welche sich fuer nichtionische kontrastmittelloesungen eigenen sowie amino-dioxepan-zwischenprodukte fuer die synthese dieser verbindungen.Info
- Publication number
- ATE14218T1 ATE14218T1 AT80304756T AT80304756T ATE14218T1 AT E14218 T1 ATE14218 T1 AT E14218T1 AT 80304756 T AT80304756 T AT 80304756T AT 80304756 T AT80304756 T AT 80304756T AT E14218 T1 ATE14218 T1 AT E14218T1
- Authority
- AT
- Austria
- Prior art keywords
- amino
- compounds
- triiodobenzoyl
- dioxepane
- synthesis
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 230000015572 biosynthetic process Effects 0.000 title 1
- REPPTOJITRHZMK-UHFFFAOYSA-N dioxepan-3-amine Chemical compound NC1CCCCOO1 REPPTOJITRHZMK-UHFFFAOYSA-N 0.000 title 1
- 239000013067 intermediate product Substances 0.000 title 1
- 239000003690 nonionic contrast media Substances 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- AGNSCOWWQUDEGE-UHFFFAOYSA-N 6-amino-1,3-dioxepan-5-ol Chemical class NC1COCOCC1O AGNSCOWWQUDEGE-UHFFFAOYSA-N 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 229940039231 contrast media Drugs 0.000 abstract 1
- 239000002872 contrast media Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 230000001766 physiological effect Effects 0.000 abstract 1
- 150000003077 polyols Chemical group 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
- C07D321/02—Seven-membered rings
- C07D321/10—Seven-membered rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
- C07D321/02—Seven-membered rings
- C07D321/04—Seven-membered rings not condensed with other rings
- C07D321/06—1,3-Dioxepines; Hydrogenated 1,3-dioxepines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11715180A | 1980-01-31 | 1980-01-31 | |
| US06/141,097 US4341756A (en) | 1980-01-31 | 1980-04-17 | Novel amino-dioxepane intermediates for the synthesis of new non-ionic contrast media |
| EP80304756A EP0033426B1 (de) | 1980-01-31 | 1980-12-30 | Trijodbenzoylderivate welche sich für nicht-ionische Kontrastmittellösungen eigenen sowie Amino-dioxepan-Zwischenprodukte für die Synthese dieser Verbindungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE14218T1 true ATE14218T1 (de) | 1985-07-15 |
Family
ID=26814974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT80304756T ATE14218T1 (de) | 1980-01-31 | 1980-12-30 | Trijodbenzoylderivate welche sich fuer nichtionische kontrastmittelloesungen eigenen sowie amino-dioxepan-zwischenprodukte fuer die synthese dieser verbindungen. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4341756A (de) |
| EP (1) | EP0033426B1 (de) |
| AT (1) | ATE14218T1 (de) |
| CA (2) | CA1161855A (de) |
| DE (1) | DE3070873D1 (de) |
| MX (1) | MX9203689A (de) |
| NL (1) | NL930068I2 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3150916A1 (de) * | 1981-12-18 | 1983-06-30 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | N-hydroxyaethylierte 2,4,6-trijodaminoisiophthalsaeure-bis- trihydroxybutylamide, deren herstellung und diese enthaltende roentgenkontrastmittel" |
| DE3150917A1 (de) * | 1981-12-18 | 1983-06-30 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | "2-amino-1-(1,3-dioxolan-4-yl)-ethanol-verbindungen, deren herstellung und verwendung zur weiterverarbeitung" |
| US4584401A (en) * | 1983-10-20 | 1986-04-22 | Biophysica Foundation | Methods and compositions involving polyhydroxylated polyiodo non-ionic contrast media |
| US5035877A (en) * | 1985-08-09 | 1991-07-30 | Cook Imaging Corporation | Non-ionic contrast media from ionic contrast media |
| DE3731542A1 (de) * | 1987-09-17 | 1989-03-30 | Schering Ag | Neue dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6-triiod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel |
| US5034499A (en) * | 1988-04-13 | 1991-07-23 | Hoechst Celanese Corp. | Acetal copolymers with backbone epoxide functional groups |
| US5698739A (en) * | 1989-07-05 | 1997-12-16 | Schering Aktiengesellschaft | Carboxamide non-ionic contrast media |
| GB8919929D0 (en) | 1989-09-04 | 1989-10-18 | Nycomed As | Compositions |
| WO1997000240A1 (en) * | 1995-06-16 | 1997-01-03 | Biophysica Foundation | Formyl derivatives as nonionic contrast media |
| US5962704A (en) * | 1995-09-26 | 1999-10-05 | Japan Tobacco Inc. | Production of amide derivatives and intermediate compounds therefor |
| WO1997011938A1 (en) * | 1995-09-26 | 1997-04-03 | Japan Tobacco Inc. | Process for producing amide derivatives and intermediate compounds |
| US6133461A (en) * | 1995-09-26 | 2000-10-17 | Japan Tobacco Inc. | Process for producing amide derivatives and intermediates therefor |
| DE19731591C2 (de) * | 1997-07-17 | 1999-09-16 | Schering Ag | Pharmazeutische Mittel enthaltend perfluoralkylgruppenhaltige Trijodaromaten und ihre Verwendung in der Tumortherapie und interventionellen Radiologie |
| US6226352B1 (en) * | 1998-09-08 | 2001-05-01 | Veritas Pharmaceuticals, Inc. | System and method for radiographic imaging of tissue |
| US20010038682A1 (en) * | 1998-09-08 | 2001-11-08 | Jesse Salb | Radiographic assessment of tissue response to compounds |
| US6723746B2 (en) * | 1998-09-08 | 2004-04-20 | Veritas Pharmaceuticals, Inc. | Functional radiographic imaging methods and agents |
| US20040170561A1 (en) * | 1998-09-08 | 2004-09-02 | Jesse Salb | Functional radiographic imaging methods and agents |
| US6751290B2 (en) | 1998-09-08 | 2004-06-15 | Veritas Pharmaceuticals, Inc. | Radiographic assessment of tissue after exposure to a compound |
| AU2002245169A1 (en) | 2000-11-10 | 2002-07-08 | Wm. Marsh Rice University | Fullerene (c60)-based x-ray contrast agent for diagnostic imaging |
| DE60220949T2 (de) | 2001-12-20 | 2008-03-06 | Bone Support Ab | Neuer knochenmineralien-ersatzstoff |
| BRPI0519754A2 (pt) | 2005-01-13 | 2009-03-10 | Cinv Ag | materiais compàsitos contendo nanopartÍculas de carbono |
| WO2010079201A1 (en) | 2009-01-09 | 2010-07-15 | Ge Healthcare As | Contrast media compositions |
| PT108524B (pt) | 2015-06-02 | 2017-12-15 | Hovione Farmaciência S A | Processo para a preparação de intermediários úteis na preparação de agentes de contraste não-iónicos |
| US10639157B2 (en) | 2017-03-14 | 2020-05-05 | Theracell, Inc. | Demineralized bone fiber composition for use in minimally invasive surgery |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4021481A (en) * | 1969-06-27 | 1977-05-03 | Nyegaard & Co. A/S | Amido derivatives of 2,4,6-triiodobenzoic acids containing at least one N-hydroxyalkyl and at least two hydroxyl groups |
| FI53066C (de) * | 1969-06-27 | 1978-02-10 | Nyegaard & Co As | |
| DE2628517C2 (de) * | 1976-06-23 | 1985-02-21 | Schering AG, 1000 Berlin und 4709 Bergkamen | Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel |
-
1980
- 1980-04-17 US US06/141,097 patent/US4341756A/en not_active Expired - Lifetime
- 1980-12-30 DE DE8080304756T patent/DE3070873D1/de not_active Expired
- 1980-12-30 EP EP80304756A patent/EP0033426B1/de not_active Expired
- 1980-12-30 AT AT80304756T patent/ATE14218T1/de active
-
1981
- 1981-01-30 CA CA000369828A patent/CA1161855A/en not_active Expired
-
1983
- 1983-10-18 CA CA000439245A patent/CA1206159A/en not_active Expired
-
1992
- 1992-06-29 MX MX9203689A patent/MX9203689A/es unknown
-
1993
- 1993-06-14 NL NL930068C patent/NL930068I2/nl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0033426B1 (de) | 1985-07-10 |
| NL930068I2 (nl) | 1994-02-16 |
| US4341756A (en) | 1982-07-27 |
| EP0033426A3 (en) | 1981-10-14 |
| DE3070873D1 (en) | 1985-08-14 |
| MX9203689A (es) | 1992-08-01 |
| CA1161855A (en) | 1984-02-07 |
| NL930068I1 (nl) | 1993-09-01 |
| EP0033426A2 (de) | 1981-08-12 |
| CA1206159A (en) | 1986-06-17 |
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