BE902611A - Derives de 4, 5, 6, 7-tetrahydroimidazo 4, 5-c pyridine. - Google Patents

Derives de 4, 5, 6, 7-tetrahydroimidazo 4, 5-c pyridine.

Info

Publication number
BE902611A
BE902611A BE0/215149A BE215149A BE902611A BE 902611 A BE902611 A BE 902611A BE 0/215149 A BE0/215149 A BE 0/215149A BE 215149 A BE215149 A BE 215149A BE 902611 A BE902611 A BE 902611A
Authority
BE
Belgium
Prior art keywords
tetrahydroimidazo
pyridine
alkyl
derivatives
alkenyl
Prior art date
Application number
BE0/215149A
Other languages
English (en)
Inventor
U Scarponi
R De Castiglione
A Verini
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of BE902611A publication Critical patent/BE902611A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Dérivé de 4,5,6,7-tétrahydroimidazo/ 4,5-c /pyridine exerçant une activité antivirale et répondant à la formule générale (I) : où R1 = H ; alcényle en C2-C4, alkyle en C2-C4, alkyle en C1-C4 ou benzyle; R2, R3 et R4 = H, alcényle en C2-C4, alkyle en C1-C4, cyclo-alkyle en C3-C7, phényle ou benzyle ; R6 et R7 = H, alcényle en C2-C4, alkyle en C1-C4, cycloalkyle en C3-C7, phényle ou benzyle ; R5 = -C (O)-R2, -C(O)-OR2, R2 ou C (Y)-NH-R6 ; Y = O ou S.
BE0/215149A 1985-01-22 1985-06-07 Derives de 4, 5, 6, 7-tetrahydroimidazo 4, 5-c pyridine. BE902611A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858501542A GB8501542D0 (en) 1985-01-22 1985-01-22 4 5 6 7-tetrahydro-imidazo(4 5-clpyridine derivatives

Publications (1)

Publication Number Publication Date
BE902611A true BE902611A (fr) 1985-09-30

Family

ID=10573211

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/215149A BE902611A (fr) 1985-01-22 1985-06-07 Derives de 4, 5, 6, 7-tetrahydroimidazo 4, 5-c pyridine.

Country Status (4)

Country Link
JP (1) JPS61167687A (fr)
BE (1) BE902611A (fr)
DE (1) DE3521303A1 (fr)
GB (2) GB8501542D0 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4812462A (en) * 1986-04-01 1989-03-14 Warner-Lambert Company 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid analogs having antihypertensive activity
US4816463A (en) * 1986-04-01 1989-03-28 Warner-Lambert Company Substituted diimidazo [1,5-a: 4',5'-d]pyridines having antihypertensive activity

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1147092A1 (fr) 1999-01-18 2001-10-24 Novo Nordisk A/S Imidazoles substitues, leur preparation et utilisation
US6908926B1 (en) 1999-04-16 2005-06-21 Novo Nordisk A/S Substituted imidazoles, their preparation and use
AU2002214505A1 (en) * 2000-11-09 2002-05-21 Biovitrum Ab New use of 4, 5, 6, 7-tetrahydroimidazo-(4,5-c)pyridine derivatives
GB0215293D0 (en) * 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
US7365094B2 (en) 2002-12-23 2008-04-29 4Sc Ag Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents
US7247736B2 (en) 2002-12-23 2007-07-24 4Sc Ag Method of identifying inhibitors of DHODH
US7071355B2 (en) 2002-12-23 2006-07-04 4 Sc Ag Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents
EP1706403B9 (fr) * 2003-12-22 2012-07-25 K.U.Leuven Research & Development Composes d'imidazo[4,5-c]pyridine et methodes de traitement antiviral
WO2006033703A1 (fr) 2004-07-27 2006-03-30 Gilead Sciences, Inc. Imidazo[4,5-d]pyrimidines, procedes d'utilisation et de preparation correspondants
SI1841765T1 (sl) 2004-12-21 2009-08-31 Gilead Sciences Inc Imidazo(4,5-c)piridinska spojina in postopek za antivirusno zdravljenje
MX2009000235A (es) 2006-07-07 2009-01-23 Gilead Sciences Inc Compuesto de piridazina novedoso y uso del mismo.
UA99466C2 (en) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Crystalline pyridazine compound
CA2992576A1 (fr) * 2015-07-16 2017-01-19 Loma Linda University Compositions pour la prevention de cancers associes a des virus du papillome humain
US10858366B2 (en) * 2016-03-08 2020-12-08 Novartis Ag Tricyclic compounds useful to treat orthomyxovirus infections
JOP20170169A1 (ar) 2016-08-29 2019-01-30 Novartis Ag مركبات بيريدازين ثلاثية الحلقة مندمجة تفيد في علاج العدوى بفيروس أورثوميكسو
CR20200372A (es) 2018-02-28 2020-10-26 Novartis Ag Derivados de 10-(di(fenil)metil)-4-hidroxi8,9,9a,10-tetrahidro-7h-pirrolo (1`, 2`:4-5) pirazino (1,2-b) piridazina-3, 5-diona y compuestos relacionados como inhibidores de la replicación del ortomixo virus para el tratamiento de la influenza

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4812462A (en) * 1986-04-01 1989-03-14 Warner-Lambert Company 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid analogs having antihypertensive activity
US4816463A (en) * 1986-04-01 1989-03-28 Warner-Lambert Company Substituted diimidazo [1,5-a: 4',5'-d]pyridines having antihypertensive activity

Also Published As

Publication number Publication date
GB2158440A (en) 1985-11-13
DE3521303A1 (de) 1985-10-31
GB8501542D0 (en) 1985-02-20
JPS61167687A (ja) 1986-07-29
GB8514278D0 (en) 1985-07-10
GB2158440B (en) 1988-06-02

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: FARMITALIA CARLO ERBA S.P.A.

Effective date: 19920630